The dimeric enzyme acts as an E1 ligase for sumo. It mediates ATP-dependent activation of sumo and formation of a thioester with a conserved cysteine residue on sae2 (By similarity).

Belongs to the ubiquitin-activating E1 family.

330 amino acids

MTNPENTPMTTTNEGGKGLTEYEAKIYDRSIRLWGVDAQAKLRQSKVLFIGINGLMSEIIKNVVLAGVDSITLVDDHIITTSDLSAHLFINEDSVGKVISTESVFAISELNPLVTIDVYDKEIETMDDQFIKNYTMVVISDKNLNNVSKVNSLCRKNNVSFIFSHSFGLKGLFFSDLNEFKYFTKTTTEPPKTETHISIFKSFKESMGYDWSKTNSRTPLPFFALSTLYQFEEKHNRVPDNISDSDLSELKSIINSSIEKFNLKNTDSNKYFEETKDLLNKMNIEISPVCAIVGGIVGAEIIKIITQNMQVLNNFFFYDGVKGTGLVEQF

37.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make sae1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here