Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

Belongs to the SecA family.

1126 amino acids

MGFNEFMTKLFGNKSQRDLKEITPYVDKVKAVYPSIKALSNDELRAKTDEIKQRIQDYVAEEKAQVEELRKGIEDKELEEREAIWAEVDKIEKAITDKMEVVLEQSLPEVFAIMKDTARRFAENEEVVVTANQFDRDLAARFDFVRIEDDKAIYANHWKAGGNEITWDMIHYDVQLFGGVVLHKGKIAEMATGEGKTLVATLPVFLNALTRNGVHVVTVNDYLSKRDSEWMGPLYMFHGLSVDCIDKHQPNSEARRKAYEADITFGTNNEFGFDYLRDNMAISPKDLVQRKHNYSIVDEVDSVLIDDARTPLIISGPIPRGEEQLFEQFRPNVEVVVNAQKDLCSKLLIEAKKKMASDDQKVVEEGSILLYRSFKGYPRNKALIKFLSEQGVKAQMLKTEEYFMSENMRHMHEATDELYFVIDEKNNSIELTDKGIDLLTGKTDDPTFFVLPDITSQLSQLENMTGTEEEKQAQKDEILANYSVKSERVHTINQLLKAYTLFEKDDEYVVMDNKVMIVDEQTGRIMDGRRYSDGLHQAIEAKERVKVEAATQTFATITLQNYFRMYHKLSGMTGTAETEAGEFWDIYKLDVVVIPTNRPIARNDMNDRIYKTKREKYNAVIEEIVQLTEAGRPVLVGTTSVEISELLSRMLTMRKIQHNVLNAKLHQKEAEIVALAGQKSTVTIATNMAGRGTDIKLSKDVKDAGGLAIIGTERHESRRVDRQLRGRAGRQGDPGSSVFFVSLEDDLMRLFASEKIAGLMDKLGFKEGEVLEHNMLSKSVERAQKKVEENNFGIRKRLLEYDDVMNSQRNVIYTRRRHALMGERIGLDVLNTIYDTSTAIADQHAEDFEGFKLELFKTFAMESPFTEDEFKSMKPEQLVEKLFEEALKTYKRRMERMTQVAHPVIKQVYENQGAMYENIMIPITDGKRMYNVSCNLKEAYDTECKAIVKSFQKSIVLHMIDEGWKEHLREMDELRHSVQNASYENKDPLLIYKLESYNLFKTMVDNMNRKTAAILMRGQIPVREEPTEEQRQAMQARQAAVAQQAAQAIAEERARQRIAVQEAAPEKHEDMSRYRTEKTDLSGNNTQAEAPQPKQAPVRAEKRVGRNDPCPCGSGKKYKNCHGQGL

129 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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