About Products Protein Database Contact

Protein expression services for Ppargc1b | Peroxisome proliferator-activated receptor gamma coactivator 1-beta

Description
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be part of the pathways regulating the elevation of gluconeogenesis, beta-oxidation of fatty acids and ketogenesis during fasting. Stimulates SREBP-mediated lipogenic gene expression in the liver. Induces energy expenditure and antagonizes obesity when overexpressed. Induces also the expression of mitochondrial genes involved in oxidative metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
Species
Rattus norvegicus
Length
1010 amino acids
Sequence
MAGNDCGALLDEELSSFFLNYLSDTQGGESGEEQLCADLPELDLSQLDASDFDSATCFGELQWCPETSETEPSQYSPDDSEFFQIDSENEALLAALTKTLDDIPEDDVGLAAFPGLDEGDTPSCTPASPAPLSVPPSPALERLLSPVSEVDELSLLQKLLLATSSPTASSDALKDGATWSQTSLSSRSQRPCVKVDGTQDKKTPMLRSQSRPCTELHKHLTSVLPCPRGKACSPPPHPSPQLLSKEDEEVGEDCPSPWPAPASPQDSLGQDTANPNSAQVPKDDVRAMVQLIRYMHTYCLPQRKLPQRASEPIPQSCSSPLRKVPPRSRQTPKAFWTEFSILRELLAQDILCDVSKPYRLATPVYASLTPQSRTRPPKDSQASPAHSAMAEEVRITASPKSTGPRPSLRPLRLEVKRDVNKPARQKREEDEEEEEEEEEEEEKEDEEEEWGRKRPGRGLPWTKLGRKMDSSVCPVRRSRRLNPELGPWLTFTDEPLGALPSMCLATETHDLEEELGGLTDSSQGQQLPLGSQIPTLESPCESGCGDTDEDPSCPRPPSRDSPRCLMLALSQSDPLGKKSFEESLTVELCGTAGLTPPTTPPYKPMEEDPFKQDTKHSPGQDTAPSLPSPETLQLTATPGASHKLPKRHPERSELLSHLQHATTQPVSQAGQKRPFSCSFGDHDYCQVIRPEAALQRKVLRSWEPIKVHLEDLAHQGATLPVETKTPRREADQNCDPTPKDSMQLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLLEEEEEEGGEEDDEGEDSGVSPPCSDHCPYQSPPSKASRQLCSRSRSSSGSSSCSSWSPATRKNFRLESRGPCSDGTPSARHAKKRREKAIGEGRVVYIRNLSGDMSSRELKKRFEVFGEIVECQVLRRSKRGQKHGFITFRCSEHAALSVRNGATLRKRNEPSFHLSYGGLRHFRWPRYTDYDPTSEESLPSSGKSKYEAMDFDSLLKEAQQSLH
Mass
111.6 kDa
Simulated SDS-PAGE
Western blot of Ppargc1b recombinant protein(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make Ppargc1b using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here