Description
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
Family
Belongs to the WD repeat EIF2A family.
Species
Caenorhabditis elegans
Sequence
MGDNLVYAVRSSEGFYLKRGLGKDAVTVFEQNKTSRDVACNVFAYSNNGQLFAYCDNQVTRVFEIATNKEILCVELKRTRKILFSPKDNFLLTFEPWAVYGPKTAENQKPEPNVRVYSLADGKHVSTFSAPKEASWEPQFSDDESLAARMVGSEVFFYTNMSFDRYDHKLVEKGATNFALSPGPAPNHVAVYVPAVGSTPARVRVHRVSESFPVVGNRTFFKSDKAVMTWNQRGQSLLILASVEVDKTNQSYYGEQSLYLINIQSGESVVVPLEKKGPIYAAKWNPNGREFAVCYGYMPAKVTFYNPRGVPIFDTIEGPRNDVFYNAFGNIVLICGFGNIAKGKMEFWDVETKKEIISIEVPNTTLFDWAPDGQHFVTCTTAPRLRIDNSYRFWHYTGRMLAETHFESPKELWEVRWRPMTGYNKFAIKELTKTDKMAAGLPIRKKDASHPLNNVPAGAVRQAGAYIPPHLRKPLGGGGSAGPPSAAAPTPGNQNQRPAQPRANGNGNAPQPFRPQQSEQERKAFQLKKKVEEIKVLKQRVANGDQLQPNQMEKIQRENEYLSELSKLTI
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service