Protein expression services for rnf138 | E3 ubiquitin-protein ligase RNF138
Description
E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination. Recruited to sites of double-strand breaks following DNA damage and specifically promotes double-strand break repair via homologous recombination (By similarity). Together with nlk.2, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with ube2k. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway (PubMed:16714285).
Species
Xenopus laevis
Length
222 amino acids
Sequence
MAEAMSCSSEITEEFLCPVCQEILQTPVRTQTCRHVFCRKCFMLAMKSGGAYCPLCRGPVNKSERSAPVRATDIDLEMRMLSGGCMYCGKMMKLHYMKLHYKSCRKYQEEYGLSPKNVTIQTGQNSTKCQEPKYKCPLCSEHNLNQRSLLEHCNNVHYYEEVEMVCPICATLPWGDPIQTTGNVIAHLNARHQFNYQEFMNINIDEEAQFQIAVANSYKISR
Mass
25.5 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
Make rnf138 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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