Description
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
Family
Belongs to the DASH complex DUO1 family.
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Sequence
MVEHKLDASTISKMIPQIFDQMRRQTGSKNFASTPASISTQSLLKEQEQLDKIIPVIQNLNERIKDCKEGDMERIKETCHAMNTILDKFISIQSQASYVNSMMNNEEYLDYVASGKSEEEYISAKQREVEELEKRVKQYTTMHAPSVKPPASKIPVGNDTRKVTKPGQRNGRSGLYSISTRNNSNNSGANGRRPPGNGNNVGRRRVYR
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service