Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.

Belongs to the cytochrome P450 family.

503 amino acids

MALWAKARVWMAGPWLSLHRARPLGTRASAAPKAVLPFEAMPRCPGNKWMRVLQIWKEQGSENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQAESLHPQRMLLEPWLAYRQARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNARGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMFKSTVQLMFVPRRLSRWTSSSMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMTLDTIKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQALRQESLVAEARISENPQRATTELPLLRAALKETLRLYPVGITLERQVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARPESYHPQRWLDRQGSGSRFPHLAFGFGMRQCLGRRVAEVEMLLLLHHVLKNFLVETLAQEDIKMVYRFILMPSTLPLFTFRAIQ

57.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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