Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.

Belongs to the radical SAM superfamily. Biotin synthase family.

335 amino acids

MANSNNQLLKEIRFDWNKEEILEILNMPLIDLMWESQTIHRKFNKYDIQLASLFSVKTGGCEENCSYCSQSIYSASEIKSHPQFQVEEVLARAQIAKKEGADRFCMGWAWREIRDGKSFNAMLEMVSGVRDLGMEACVTAGMLTEEQAARLADAGLTAYNHNLDTSPEHYKNIITTRTYQDRLDTIKRVRNAGINVCCGGIIGLGETNGDRASLLKVLSNMNPHPESVPINSLVAIEGTGLEDNQEIDSIEMIRMIATARILMPKSKIRLSAGREKLSKEAQILCFQCGANSIFYGDELLTTSNPSFQSDRKLLKEVGVSFNKDFETREKTLSSL

37.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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