Catalyzes the isomerization of citrate to isocitrate via cis-aconitate, a step in the citric acid cycle. Also catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.

Belongs to the aconitase/IPM isomerase family.

787 amino acids

MISTRLARAGALAPKSRLFLGTRAFATVGDSPLDKKVEMANTEKGNYINYKKMSENLDIVRRRLQRPLTYAEKVLYSHLDDPHGQEIERGKSYLKLRPDRVACQDATAQMAILQFMSAGMPSVATPTTVHCDHLIEAQVGGDKDLARANEINKEVYDFLASATAKYNIGFWKPGSGIIHQIVLENYAFPGGLMIGTDSHTPNAGGLAMAAIGVGGADAVDVMAGLPWELKAPKVIGVKLTGEMSGWTTPKDVILKVAGLLTVKGGTGAIIEYHGPGVTSLSCTGMGTICNMGAEIGATTSMFPFNDRMYDYLKATKRQHIGDFAREYAKELREDEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVETNKWPEELKVGLIGSCTNSSYEDMSRAASIARDALNHGLKAKSLFTVTPGSEQIRATIERDGQLQTLEEFGGVILANACGPCIGQWDRRDVKKGEPNSIISSYNRNFTGRNDANPATHAFVASPDLVVAMTIAGTLKFNPLTDKLKDKDGNEFLLQPPTGEGLPAKGYDPGRDTYQAPPADRSSVNVAVSPTSDRLQLLAGFEPWDGKDANGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNAENGKANSVKNKFTGEYDAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGLAIITRSFARIHETNLKKQGMLPLTFADPADYDKINPEDTVDLLCTQLEVGKPMTLRVHPKDGSAPFDISLNHTFNESQIEWFKDGSALNTMARKSGAK

85.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make acoA using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here