Description
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).
Family
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
Species
Yarrowia lipolytica (strain CLIB 122 / E 150)
Sequence
MENTKRREFSHPYTPYPIQVDFMEALYDCIESYKVGIFESPTGTGKTLSLICGSMTWLRKNKAQLAVSTASADENEPAWVLEQTIQLAREEFSRNREMLQKRLDKMRRKNMRARISYEQGFKRAKKAPEPVDDSQFLPEDYSEVIKPEVQRLLSALAPPVENDFQEPVKIIFASRTHSQLSQFVGQMQHTTFPPSSDLQDLESTKLISLGSRKQLCINPRVSHMNSVQAMNDACRDLREGKKGGCKYYKNPHDALGKVDINTFRDTTLAEILDIEDLYKLGKHTSTCPYYASRASIPASEVITVPYQILLSRSARKAIDLPVKNSIVIIDEAHNLLDTITSLHTMSITKSQVSSASSGLQKYQHKFQNRLNSGNRVNLGYLVNMLQALEVFFEKAQKFHKKETAPGTPVTTSSLFDGSTADLINVNRLEKYIDESKIVFKIESYLEHVNGETQEKSHSSSLVLSSVMEFLRQVNNPDSEGVLCFDGPTKLKYQLLDPSEPFKDIVENARCVVLAGGTMEPTGDYLEYLLPYLSQDQIKLFSCGHVIPPQNLSVQVIPNGPNYSFNFTFDKRNDEKMILDVAITLLVYSKIIPEGMVVFFPSYKYLEQVVAVWKKAKKDGKNIYEILNDQKRIFVESQHDSVEKTLSEYAEEVPKGAILLSVVGGKMSEGINFSDGLARAVFMIGLPFPNLMSAEIIAKRKYIEQSVSEKMKAKGVSAKEALEASKGAARDFYMNICLRAVNQSVGRAIRHANDYACIFLLDGRFGKPEIQKKLSKWMREGIREGSFKEALGEVQQFFASHEKN
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service