Protein expression services for cldD | (12E)-labda-8(17),12,14-triene synthase
Description
Involved in the biosynthesis of the mercapturic acid derivative diterpene cyslabdan A, a potentiator of the beta-lactam antibiotic imipenem (PubMed:26507838). Catalyzes the conversion of (+)-copalyl diphosphate to yield labda-8(17),12(E),14-triene (biformene) (PubMed:26507838, PubMed:26814669).
Family
Belongs to the terpene synthase family.
Species
Streptomyces cyslabdanicus
Length
329 amino acids
Sequence
MTRTGDAVTILPQPDFTATFPGPFPTSPHGERTERQLLGWLEEYPLLPSARARSVLVNITSHGVSRTLPTADADDLVLFAELLLWLTAFDDMHGESNAARDLVALVDRTAELTLVLAGGSPPPLTNPFPAALYDLLARFRARTGPAAYLRLAASLRDTIMALVWEAHHVAEPERVALETYLEMRPHTVFVRTIFAAAEIVLDYELTDAQRALAPVRHLETAVANLAGWINDLASYEREAARGPAQPLSLPTLLRARHGGSLEEAFARAGGMCENEAAVARQGITSLAGDPPSALTAHARALEDIARSFVWHTSHARYQGPKRGAAPTSR
Mass
35.7 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make cldD using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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