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zur

Gene
zur
Protein
Zinc uptake regulation protein
Organism
Escherichia coli (strain K12)
Length
171 amino acids
Function
Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB).
Similarity
Belongs to the Fur family.
Mass
19.254 kDa
Sequence
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQHDHSVQVKKKPR

Gene
zur
Protein
Zinc uptake regulation protein
Organism
Shigella flexneri
Length
171 amino acids
Function
Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB).
Similarity
Belongs to the Fur family.
Mass
19.254 kDa
Sequence
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQHDHSVQVKKKPR

Gene
zur
Protein
Zinc-specific metallo-regulatory protein
Organism
Bacillus subtilis (strain 168)
Length
145 amino acids
Function
Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake, yciC and ycdHIyceA. Also represses the expression of rpmE2, the gene for ribosomal protein L31B, which is expressed only after the end of exponential growth.
Similarity
Belongs to the Fur family.
Mass
16.637 kDa
Sequence
MNVQEALNLLKENGYKYTNKREDMLQLFADSDRYLTAKNVLSALNDDYPGLSFDTIYRNLSLYEELGILETTELSGEKLFRFKCSFTHHHHHFICLACGKTKEIESCPMDKLCDDLDGYQVSGHKFEIYGTCPDCTAENQENTTA

Gene
zur
Protein
Zinc uptake regulation protein
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
130 amino acids
Function
Global transcriptional regulator involved in zinc homeostasis.
Similarity
Belongs to the Fur family.
Mass
14.398 kDa
Sequence
MSAAGVRSTRQRAAISTLLETLDDFRSAQELHDELRRRGENIGLTTVYRTLQSMASSGLVDTLHTDTGESVYRRCSEHHHHHLVCRSCGSTIEVGDHEVEAWAAEVATKHGFSDVSHTIEIFGTCSDCRS

Gene
zur
Protein
Zinc uptake regulation protein
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
130 amino acids
Function
Global transcriptional regulator involved in zinc homeostasis. Represses the transcription of at least 32 genes, including genes involved in zinc homeostasis, by binding to promoter sequences that contain a conserved 26 bp palindrome, in the presence of zinc.
Similarity
Belongs to the Fur family.
Mass
14.398 kDa
Sequence
MSAAGVRSTRQRAAISTLLETLDDFRSAQELHDELRRRGENIGLTTVYRTLQSMASSGLVDTLHTDTGESVYRRCSEHHHHHLVCRSCGSTIEVGDHEVEAWAAEVATKHGFSDVSHTIEIFGTCSDCRS