Organism
Drosophila melanogaster
Function
Structural component of the gap junctions in germline cells. Required for differentiation and survival of germline cysts in females and of spermatogonia in males; gap junctional communication between spermatogonia and somatic cyst cells may be required for normal differentiation and survival of spermatogonia.
Similarity
Belongs to the pannexin family.
Sequence
MYAAVKPLSKYLQFKSVHIYDAIFTLHSKVTVALLLACTFLLSSKQYFGDPIQCFGDKDMDYVHAFCWIYGAYVSDNVTVTPLRNGAAQCRPDAVSKVVPPENRNYITYYQWVVLVLLLESFVFYMPAFLWKIWEGGRLKHLCDDFHKMAVCKDKSRTHLRVLVNYFSSDYKETHFRYFVSYVFCEILNLSISILNFLLLDVFFGGFWGRYRNALLSLYNGDYNQWNIITMAVFPKCAKCEMYKGGPSGSSNIYDYLCLLPLNILNEKIFAFLWIWFILVAMLISLKFLYRLATVLYPGMRLQLLRARARFMPKKHLQVALRNCSFGDWFVLMRVGNNISPELFRKLLEELYEAQSLIKIPPGADKI