Protein
DNA gyrase inhibitor YacG
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
Similarity
Belongs to the DNA gyrase inhibitor YacG family.
Sequence
MSQPLTVECPTCGAPVEWKSDNKYRPFCSDRCKLIDLGAWAAEEHAIPGDTLEDDIFSADLPPREH