wecB

Gene

wecB

Protein

UDP-N-acetylglucosamine 2-epimerase

Organism

Escherichia coli O157:H7

Length

376 amino acids

Function

Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.

Similarity

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

Mass

42.248 kDa

Sequence

MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLRENVADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESFGRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVEEVTRLLKDENEYQTMSRAHNPYGDGQACSRILEALKNNRISL

Protein

UDP-N-acetylglucosamine 2-epimerase: wecB

Gene

wecB

Protein

UDP-N-acetylglucosamine 2-epimerase

Organism

Escherichia coli (strain K12)

Length

376 amino acids

Function

Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. Also involved in bacteriophage N4 adsorption.

Similarity

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

Mass

42.245 kDa

Sequence

MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLRENVADSRIFITGNTVIDALLWVRDQVMSSDKLRSELAANYPFIDPDKKMILVTGHRRESFGRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVEEVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL

Protein

UDP-N-acetylglucosamine 2-epimerase: wecB

Gene

wecB

Protein

UDP-N-acetylglucosamine 2-epimerase

Organism

Salmonella typhi

Length

376 amino acids

Function

Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.

Similarity

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

Mass

42.265 kDa

Sequence

MKVLTVFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLDQVLTLFSIVPDYDLNIMQPGQGLTEITCRILERLKPILADFKPDVVLVHGDTTTTIATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLRENIPDERIFVTGNTVIDALIWVRDRVLTSDTLQAELAEQYPFLNANKKMILVTGHRRESFGQGFEHICQALAEIAAANQNVQIVYPVHLNPNVSEPVNRILGHVENVVLIEPQDYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRETTERPEAITAGTVRLIGTDSRRIVAEVMRLLHDENEYQTMSRAHNPYGDGQSCARILQALKSYRVSL

Protein

UDP-N-acetylglucosamine 2-epimerase: wecB

Gene

wecB

Protein

UDP-N-acetylglucosamine 2-epimerase

Organism

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Length

376 amino acids

Function

Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.

Similarity

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

Mass

42.165 kDa

Sequence

MKVLTVFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLDQVLTLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILADFKPDVVLVHGDTTTTIATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLRENIPDERIFVTGNTVIDALIWVRDRVLTSDTLQAELAEQYPFLNANKKMILVTGHRRESFGQGFEHICQALAEIAAANQNVQIVYPVHLNPNVSEPVNRILGHVENVVLIEPQDYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRETTERPEAITAGTVRLIGTDSRRIVAEVMRLLHDENEYQTMSRAHNPYGDGQSCARILQALKSYRVSL

Protein

UDP-N-acetylglucosamine 2-epimerase: wecB

Gene

wecB

Protein

UDP-N-acetylglucosamine 2-epimerase

Organism

Yersinia pestis

Length

376 amino acids

Function

Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.

Similarity

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

Mass

42.379 kDa

Sequence

MKVLTVFGTRPEAIKMAPLVHALAQDDAFESRVCVTAQHREMLDQVLRLFEIQPDYDLDIMRPGQGLTEITCRILEGLKPVLEEFKPDVILVHGDTTTTLSASLAGFYHRIPVGHVEAGLRTGDLYSPWPEEANRQLTGHLAMYHFAPTENSRQNLLREWVPENRIFVTGNTVIDALFWVRDRVMNTPDLRANLAQRYAFLDTNKKMILVTGHRRESFGGGFERICSALAEIARKHPEVQVVYPVHLNPNVSEPVNRILKGIDNIILIDPQDYLPFVYLMNHAYLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVDSGTVLLVGTNINKIVDAVTRLLTDETAYHQMTRAHNPYGDGYACQRILKALKNHQVTL

Protein

UDP-N-acetylglucosamine 2-epimerase: wecB

Gene

wecB

Protein

UDP-N-acetylglucosamine 2-epimerase

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

Length

366 amino acids

Function

Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.

Similarity

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

Mass

41.726 kDa

Sequence

MKLSIILGTRPEIIKLSPIIRALEKTNIDWHIIHTNQHYSENMDKIFFEELNLPNPKYNLNIGSGTHGEQTGKMLIEIEKVLLKEKPDVVVVQGDTNTVLAGALVASKLKIDVAHVEAGLRSFDRNMPEEINRVLTDHISSYLFAPTEIAKNNLLREGIEENKIFVVGNTIVDATLQNLKIAEKNENVRAFFNSVVIDDDYFLLTLHRAENVDNKERLKNIVEGIFEIIEIYDKAIIFSIHPRTKKRLKEFNLFDKLKSNKKIKIIEPVGYLEFLMLEKNAELILTDSGGVQEEACILKVPCITLRDNTERPETVEVGANILVGDNKEKLIKAVEIMLNKKRNWKNPFGNGKSGERIVRILTYGKY

Protein

UDP-N-acetylglucosamine 2-epimerase: wecB

Gene

wecB

Protein

UDP-N-acetylglucosamine 2-epimerase

Organism

Methanococcus maripaludis (strain S2 / LL)

Length

366 amino acids

Function

Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.

Similarity

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

Mass

41.356 kDa

Sequence

MYKIGIILGTRPEIIKMSPVIRELTTKKFFLIHTNQHYSENMDKIFFEELNLKKPDYNLNIGSGSHGDQTGRMLMEIEKVLLKEKPDFVLVQGDTNTVLAGALAASKLGIKIGHIEAGLRSFDRKMPEETNRVLTDHISEFLFAPTKTAANNILKEGISDEKIHIVGNTIVDATIQNLKIAEKNEKVCKFISKITKNEKYFLLTLHRAENTDNFEILSKLVTSINNISKKYEKNIIFPIHPRTHKKLNEFGLINKLENNHLIKIIEPVGYLEFLGLEKNAELIITDSGGLQEEACILNVPCVTLRENTERPETLDVNSNILAGSDPENILNCVEKMLKSNRHWNNPFGDGNSGKIIVNIVFGEKKP

Protein

UDP-N-acetylglucosamine 2-epimerase: wecB