vrdA

Versiconal hemiacetal acetate reductase

343 amino acids

Catalyzes 3 reactions: from hydroxyversicolorone (HVN) to versicolorone (VONE), from versiconal hemiacetal acetate (VHA) to versiconol acetate (VOAc) and from versiconal (VHOH) to versiconol (VOH). Probably not an aflatoxin biosynthesis gene: may be involved in the vertical branching steps connecting the main pathway from HVN to VHOH with the side pathway from VONE to VOH.

Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.

38.698 kDa

MEYARLGDSGLKVSKVILGCMGYGSPEWQGWVLNEEESLPLIEHAYNKGIRTWDTADMYSHGKSEEIVGKALKKYNIPRSRVVILTKCYFGVDDQGNFPSPLSTGRQNEGDYLNRVGLSRRHILEAVDASVERLGTYIDVLQIHRLDRETPREEIMRALNDVVESGKARYIGASSMAAWEFQTLQNIAIRNGWHKFISMQNYHNLIAREEEREMIPYCLDSGVSLIPWSPVARGALARPWASRSTLRENTDAGISILVRARESESDKAIIDRVEELADKKGISMAQVAIAWSLSHPSEYPIVGLNTKDRIDEAVASVQVKLTPEEIQYLEEPYVPKAIHPGER