Protein
Probable ATP-dependent RNA helicase vasa-like
Function
Involved in translational control mechanisms operating in early stages of oogenesis. Required maternally in many stages of oogenesis, including cystocyte differentiation, oocyte differentiation, and specification of anterior-posterior polarity in the developing cysts. Essential for the formation and/or structural integrity of perinuclear nuage particles during germ cell formation.
Similarity
Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
Sequence
MSDDWDETDAAPASDWNIESFGLPTSFGSTKKTCNTGNAFNDGEGGFDEGSQSNFDDPFRSGGGGFGGRGRGGPRACFKCGDEGHMARDCPSASDSRGNRTNNRRQDNWGGGSSSKPANGEPFGFGSAFGDNQESDPFGATESSGFGFGSGSGSRGGRRNDGGRGCFKCGEEGHMSRDCPSGGGRNKGCFKCGQEGHNARDCPNPGEGSEEKKPRAPLYIPADVNEDELFVMGIEAGSNFDAYANVPANVSGAEPIQPAAESFQSMNLRPLLLENIVKAGYGCPTPVQKYTIPNVMNGRDIMACAQTGSGKTAAFLLPMLHYILDNNCPSNAFEEPAQPTGLVICPTRELAIQIMREARKFSHSSVAKCCVAYGGAAGFHQLKTIHSGCHILVATPGRLLDFLEKGKIVFSSLKYLVLDEADRMLDMGFLSSIKTVINHKTMTPTAERITLMFSATFPHEIQELASAFLNNYLFVVVGTVGAANTDVKQEVLCVPKFEKKAKLVEMCEEILISADDEKILVFVEQKRVADFVGTYLCEKKFRATTMHGDRYQAQREQALSEFRTGVHNILVATAVTARGLDIKGIGVVVNYDLPKDIDEYVHRIGRTGRLGNRGLSISFYDDETDACLTKDLVKVLSEANQTIPDWLTQKANASGHAQTYHGSGLFASSDIRSKNGGGRGWEKNQASSFLGGPSESNVDEEWD