ung1

Gene

UNG1

Protein

Uracil-DNA glycosylase

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

359 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Not involved in strand-directed mismatch repair.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

40.471 kDa

Sequence

MWCMRRLPTNSVMTVARKRKQTTIEDFFGTKKSTNEAPNKKGKSGATFMTITNGAAIKTETKAVAKEANTDKYPANSNAKDVYSKNLSSNLRTLLSLELETIDDSWFPHLMDEFKKPYFVKLKQFVTKEQADHTVFPPAKDIYSWTRLTPFNKVKVVIIGQDPYHNFNQAHGLAFSVKPPTPAPPSLKNIYKELKQEYPDFVEDNKVGDLTHWASQGVLLLNTSLTVRAHNANSHSKHGWETFTKRVVQLLIQDREADGKSLVFLLWGNNAIKLVESLLGSTSVGSGSKYPNIMVMKSVHPSPLSASRGFFGTNHFKMINDWLYNTRGEKMIDWSVVPGTSLREVQEANARLESESKDP

Protein

Uracil-DNA glycosylase: UNG1

Gene

ung1

Protein

Uracil-DNA glycosylase

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

322 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

36.705 kDa

Sequence

MTVLNTTDKRKADDTVNKLDGKLKQPRLDNFFKTNTSSPALKDTQVLDNKENNSVSKFNKEKWAENLTPAQRKLLQLEIDTLESSWFDALKDEFLKPYFLNLKEFLMKEWQSQRVFPPKEDIYSWSHHTPLHKTKVILLGQDPYHNIGQAHGLCFSVRPGIPCPPSLVNIYKAIKIDYPDFVIPKTGYLVPWADQGILMLNASLTVRAHQAASHSGKGWETFTSAVLQVALNRNRKGLVILAWGTPAAKRLQGLPLKAHYVLRSVHPSPLSAHRGFFECHHFKKTNEWLEEQYGPEKCINWSAVSEQKAKIKSSELESSSTE

Protein

Uracil-DNA glycosylase: ung1

Gene

ung1

Protein

Uracil-DNA glycosylase 1

Organism

Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

Length

225 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

24.41 kDa

Sequence

MAPRPLHELVEAGWAKALDPVAGRIAAMGDFLRAEVAAGRTYLPAGANVLRAFQQPFDDVRVLIVGQDPYPTPGMAIGLSFAVSPEVRSLPGSLENIFRELHTDLGLPRPSNGDLTPWTEQGVLLLNRALTTAPRKPAAHRGKGWEEVTEQAIRALVARGTPLVSVLWGRDARNLRPLLGDLPAIESAHPSPMSADRGFFGSRPFSRANELLVRQGAQPVDWRLP

Protein

Uracil-DNA glycosylase 1: ung1

Gene

ung1

Protein

Uracil-DNA glycosylase 1

Organism

Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

Length

225 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

24.456 kDa

Sequence

MAPRPLNEIVEAGWAKALEPVAGQITSMGEFLRAEIAAGRTYLPAGANVLRAFQQPFDDVRVLIVGQDPYPTPGHAVGLSFSVAPEVRPLPGSLVNIFRELNTDLNLPQPANGDLTPWTRQGVLLLNRALTTAPRKPAAHRGKGWEEVTEQAIRALAARGKPMVSILWGRDARNLRPLLGDLPALESAHPSPMSADRGFFGSRPFSRANDLLMRLGGQPVDWRLP

Protein

Uracil-DNA glycosylase 1: ung1

Gene

ung1

Protein

Uracil-DNA glycosylase 1

Organism

Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)

Length

221 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

25.047 kDa

Sequence

MVKTWDEFLEQEAKQPYFIELMKAVSEAREEGNVYPSEEDMFSCFRLCPYDKVKVVILGQDPYHGPGQAHGLSFSVQKDVRIPPSLRNIYKELKSDLDIDPANHGYLAKWAEQGVLLMNTSWSVEEGKAGSHKKLGWATFTDHVLEELNNYDKPLVFILWGNHAIKAASGITNPKHLLIKGVHPSPLAASRGFFGSKPFSKTNEFLKENNRTPIDWDLNSK

Protein

Uracil-DNA glycosylase 1: ung1

Gene

ung1

Protein

Uracil-DNA glycosylase 1

Organism

Listeria monocytogenes serotype 4b (strain F2365)

Length

221 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

25.065 kDa

Sequence

MVKTWEEFLKQEAKQPYFIELMEAVKDARAKGNVYPTEEDMFSCFRLCPYDQVKVVILGQDPYHGPGQAHGLSFSVQKGVRIPPSLRNIYKELKTDLDIEPADHGYLAKWAEQGVLLMNTSWSVEEGKAGSHKKLGWATFTDHVLEELNNYDKPLVFILWGNHAIKAASGITNPQHLLIKGVHPSPLAASRGFFESKPFSKTNAFLEEHGRKPIDWDLNEQ

Protein

Uracil-DNA glycosylase 1: ung1

Gene

ung1

Protein

Uracil-DNA glycosylase 1

Organism

Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)

Length

221 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

25.108 kDa

Sequence

MVKTWEEFLKQEAKQPYFIELMEAVKDARAKGNVYPSEEDMFSCFRLCPYNQVKVVILGQDPYHGPGQAHGLSFSVQKDVRIPPSLRNIYKELKTDLDIEPADHGYLAKWAEQGVLLMNTSWSVEEGKAGSHKKLGWATFTDHVLEELNNYDKPLVFILWGNHAIKAASGITNPQHLIIKGVHPSPLAASRGFFGSKPFSKTNAFLEEHERKPIDWDLNEQ

Protein

Uracil-DNA glycosylase 1: ung1

Gene

ung1

Protein

Uracil-DNA glycosylase 1

Organism

Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)

Length

220 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

25.126 kDa

Sequence

MNVKIESSWQQRLQEEFDKPYFEKLVNFVKNEYGKAHILPPGHQIFHVFNSCPFQNVKVVILGQDPYPNPGQYYGICFSVPDGVAIPGSLSNIFKEIHQDLGKPLPNSGNLDRWVKQGVFPMNSVLTVRAHETGSHRNIGWETFTDAVIKKLSEERENLVFMLWGSYAKEKASLIDTDKHLILTAVHPSPRSADYGFFGCKHFSKANTFLRSRGIEEIDW

Protein

Uracil-DNA glycosylase 1: ung1

Gene

ung1

Protein

Uracil-DNA glycosylase 1

Organism

Bacteroides fragilis (strain YCH46)

Length

220 amino acids

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Similarity

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Mass

25.126 kDa

Sequence

MNVKIESSWQQRLQEEFDKPYFEKLVNFVKNEYGKAHILPPGHQIFHVFNSCPFQNVKVVILGQDPYPNPGQYYGICFSVPDGVAIPGSLSNIFKEIHQDLGKPIPNSGNLDRWVKQGVFPMNSVLTVRAHETGSHRNIGWETFTDAVIKKLSEERENLVFMLWGSYAKEKASLIDTDKHLILTAVHPSPRSADYGFFGCKHFSKANTFLRSRGIEEIDW

Protein

Uracil-DNA glycosylase 1: ung1