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ump1

Gene
UMP1
Protein
Proteasome maturation factor UMP1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
148 amino acids
Function
Short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. Required for the correct assembly and enzymatic activation of the proteasome. Also prevents premature processing of the PRE2 propeptide.
Similarity
Belongs to the POMP/UMP1 family.
Mass
16.76 kDa
Sequence
MNIVPQDTFKSQVSTDQDKSVLSSAVPSLPDTLRQQEGGAVPLSTQLNDRHPLESTLKNWETTQRQRQMEQYRQIFGIAEPMKRTMEMEIVNRTDFNPLSTNGSIHRDILLNKECSIDWEDVYPGTGLQASTMVGDDVHSKIEKQLGI

Gene
ump1
Protein
Probable proteasome maturation factor ump1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
129 amino acids
Function
Short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. Required for the correct assembly and enzymatic activation of the proteasome (By similarity).
Similarity
Belongs to the POMP/UMP1 family.
Mass
14.661 kDa
Sequence
MKIVPDVEPAAEVSGNFKVSVLEPSIPAVHRVENKHPLESRLKNWEAQQQQIRLDSMRRIYGLHEPVRREMEQKLASQSSRPLALGGSANFHLDILANREAVLDETDIYAAPIPLEMTYQNEMAIRYGL