ULP1

Ubiquitin-like-specific protease 1

621 amino acids

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SMT3 to its mature form and deconjugation of SMT3 from targeted proteins. Has an essential role in the G2/M phase of the cell cycle.

Belongs to the peptidase C48 family.

72.378 kDa

MSVEVDKHRNTLQYHKKNPYSPLFSPISTYRCYPRVLNNPSESRRSASFSGIYKKRTNTSRFNYLNDRRVLSMEESMKDGSDRASKAGFIGGIRETLWNSGKYLWHTFVKNEPRNFDGSEVEASGNSDVESRSSGSRSSDVPYGLRENYSSDTRKHKFDTSTWALPNKRRRIESEGVGTPSTSPISSLASQKSNCDSDNSITFSRDPFGWNKWKTSAIGSNSENNTSDQKNSYDRRQYGTAFIRKKKVAKQNINNTKLVSRAQSEEVTYLRQIFNGEYKVPKILKEERERQLKLMDMDKEKDTGLKKSIIDLTEKIKTILIENNKNRLQTRNENDDDLVFVKEKKISSLERKHKDYLNQKLKFDRSILEFEKDFKRYNEILNERKKIQEDLKKKKEQLAKKKLVPELNEKDDDQVQKALASRENTQLMNRDNIEITVRDFKTLAPRRWLNDTIIEFFMKYIEKSTPNTVAFNSFFYTNLSERGYQGVRRWMKRKKTQIDKLDKIFTPINLNQSHWALGIIDLKKKTIGYVDSLSNGPNAMSFAILTDLQKYVMEESKHTIGEDFDLIHLDCPQQPNGYDCGIYVCMNTLYGSADAPLDFDYKDAIRMRRFIAHLILTDALK

ulp1

Ubiquitin-like-specific protease 1

568 amino acids

A cysteine protease that proteolytically removes the C-terminus of pmt3.

Belongs to the peptidase C48 family.

64.941 kDa

MIGKRNASKRTRQDDCITYEEYQRKRKKTFLNTFVNICSRTVTYAKLFLTKTPISELDRIAGEAIPSNSNSTNSKLEPSTKAPESRFSHINSKTERGYVTVESDMSSHNTLDRNSKPTVSHSYTNSSKDEKFLDPIALQNLFSPASDTHSQNIHDEALSPSSFRVSRSRYFPRPHRSSKNLSVSNRLQLAVFKETTSSTLSHGNSVEADEINSFNPTPFSSSPLHFTNSSPNPNSDIVTPDKQLDVVSEHARYKHLPFTATLRKKSPHDSTSRKASFRFVQSDQQPARNIVTSDIQNEKSLLLLIRDLKEKQTESFQDWNEVDFLQLKGLEISPPPTRPKFIPELEFPDNARKRALKYLNQSNSVSSSEPIITKFNIPITLKDLHTLRNRQWLNDEVINFYMNLISERSKIDSSLPRVHGFNTFFYTSLQRRGYAGVRRWAKKARVNIADMDAVFIPVHLDVHWCMAVINKSKKRFEYWDSLAGSPGKVFDLLRDYYIAETKGAVDVSDWENFMDDNSPRQRNGHDCGVFACKTAECVSRNVPVQFSQNDMPELRIKMAASIIDAQIY