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uhpB

Gene
uhpB
Protein
Signal transduction histidine-protein kinase/phosphatase UhpB
Organism
Escherichia coli (strain K12)
Length
500 amino acids
Function
Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpB functions as a membrane-associated protein kinase that autophosphorylates in response to interaction with UhpC, and subsequently transfers its phosphate group to the response regulator UhpA (PubMed:3038843, PubMed:8349544, PubMed:11053370, PubMed:11739766). Can also dephosphorylate UhpA (PubMed:11053370, PubMed:11739766).
Mass
56.306 kDa
Sequence
MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFPFGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISRYRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWHYLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALPIIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRLRELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLAADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV

Gene
uhpB
Protein
Signal transduction histidine-protein kinase/phosphatase UhpB
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
500 amino acids
Function
Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpB functions as a membrane-associated protein kinase that autophosphorylates in response to interaction with UhpC, and subsequently transfers its phosphate group to the response regulator UhpA. Can also dephosphorylate UhpA.
Mass
55.891 kDa
Sequence
MNTFFSRLITVVACFFIFSAAWFCLWSISLHLVERPELAALLFPFGLRLGLMLQCPRGYWPVLLGAEWLLVYWLAQEVALAHLPLLMIGSVLTLLPVALTSRYRHQRDWRTLLLQGAALTAAALLQSLPWLGQGEEAWNALLLTLTGGLTLAPICLVFWHYLTSTTWLPLGPSLVSQPVNWRGRHLIWYLLLFIVSLWLQLGLPAELSRFTPFCLALPIIALAWHYGWQGALIATLMNAIALIASQTWHDHPVDLLLSLLAQSLTGLLLGAGIQRLRELNQSLQKELARNHRLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLAADNGGVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLAQAIRSLLREMELESRGIVSHLDWRIDETALSESQRVTLFRVCQEGLNNIVKHANASAVTLQGWQQDERLMLVIEDDGSGLPPGSHQQGFGLTGMRERVSALGGTLTISCTHGTRVSVSLPQRYV