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udgB

Gene
udgB
Protein
Type-5 uracil-DNA glycosylase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
268 amino acids
Function
DNA glycosylase with broad substrate specificity.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
Mass
28.5 kDa
Sequence
MHPKTGRAFRSPVEPGSGWPGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREEVAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTGDRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPTPAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLAGASGTPKPRFGHGVVTELGAGVRLLGCYHPSQQNMFTGRLTPTMLDDIFREAKKLAGIE
Protein
Type-5 uracil-DNA glycosylase: udgB

Gene
udgB
Protein
Type-5 uracil-DNA glycosylase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
268 amino acids
Function
DNA glycosylase with broad substrate specificity. Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair. Can also excise ethenocytosine and hypoxanthine from double-stranded DNA.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
Mass
28.5 kDa
Sequence
MHPKTGRAFRSPVEPGSGWPGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREEVAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTGDRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPTPAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLAGASGTPKPRFGHGVVTELGAGVRLLGCYHPSQQNMFTGRLTPTMLDDIFREAKKLAGIE
Protein
Type-5 uracil-DNA glycosylase: udgB

Gene
udgB
Protein
Type-5 uracil-DNA glycosylase
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
268 amino acids
Function
DNA glycosylase with broad substrate specificity.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
Mass
28.5 kDa
Sequence
MHPKTGRAFRSPVEPGSGWPGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREEVAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTGDRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPTPAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLAGASGTPKPRFGHGVVTELGAGVRLLGCYHPSQQNMFTGRLTPTMLDDIFREAKKLAGIE
Protein
Type-5 uracil-DNA glycosylase: udgB

Gene
udgB
Protein
Type-5 uracil-DNA glycosylase
Organism
Mycobacterium leprae (strain TN)
Length
229 amino acids
Function
DNA glycosylase with broad substrate specificity.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
Mass
24.937 kDa
Sequence
MLSGGAGSIPELNAQISVCRACPRLVDWREEVAVVKRRAFADQPYWGRPVPGWGSEQPRLLIVGLAPAAHGANRTGRMFTGDRSGDQLYAALHRAGLVNLPISMDAADGLQANQIRITAPVRCAPPGNAPTQAEWVTCSPWLEAEWRLVSEYVRAIVALGGFAWQIVLRLPGVSAMRKPRFSHGVVAQLYAGVRLLGCYHPSQQNMFTGRLTPAMLDDIFRDAKKLAGI
Protein
Type-5 uracil-DNA glycosylase: udgB

Gene
udgb
Protein
Type-5 uracil-DNA glycosylase
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
219 amino acids
Function
DNA glycosylase with broad substrate specificity. Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair (PubMed:12000829, PubMed:17870091, PubMed:24838246). Can also excise hypoxanthine from double-stranded DNA containing G/I, T/I, and A/I base pairs, xanthine from both double-stranded and single stranded DNA, thymine from G/T mismatched DNA, 5'-hydroxymethyluracil and 5'-fluorouracil (PubMed:17870091, PubMed:24838246).
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
Mass
24.286 kDa
Sequence
MDREAFVQTLTACRLCPRLVAWREEVVGRKRAFRGEPYWARPVPGFGDPEARILLFGLAPGAHGSNRTGRPFTGDASGAFLYPLLHEAGLSSKPESLPGDDLRLYGVYLTAAVRCAPPKNKPTPEELRACARWTEVELGLLPEVRVYVALGRIALEALLAHFGLRKSAHPFRHGAHYPLPGGRHLLASYHVSRQNTQTGRLTREMFLEVLMEAKRLAGL
Protein
Type-5 uracil-DNA glycosylase: udgb