Protein
Toluene efflux pump periplasmic linker protein TtgA
Organism
Pseudomonas putida (strain DOT-T1E)
Function
The periplasmic linker protein component of a constitutive organic solvent efflux system. Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
Similarity
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
Sequence
MQFKPAVTALVSAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTLTSELPGRTSAYRVAEVRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAERYKQLIDEQAVSKQEYDDANAKRLQAEASLKSAQIDLRYTKVLAPISGRIGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGNNAASVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVNANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRLITEGLQYVRPGVEVKVSDATNVKKPAGPDQANAAKADAKAE