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tsp-15

Gene
tsp-15
Protein
Tetraspanin-15
Organism
Caenorhabditis elegans
Length
258 amino acids
Function
Plays a role in cuticle biogenesis (PubMed:15454573, PubMed:23028364, PubMed:25480962). In complex with doxa-1 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix (PubMed:23028364).
Similarity
Belongs to the tetraspanin (TM4SF) family.
Mass
29.028 kDa
Sequence
MGALGDSAYGARGRLIKFSYIVTALISILFSISCICYGIWLLARRSQYAELVSPSLYVDVGRILVIISILSILNYLICFYAIFKEMRCFVTSCAVASIVIAVMLIIGGCIGLNFRDQLTHYTPLNLKMLTSLRELYGTHDMKGITESWDALQSNFKCCGVNGTDNAQIWKTSKWYMHQRAPKLLIPESCCIPSEIERCRSNPFDQDAPPPYYTSTCYEPLQNDLLHVMNVASWLCITNAIVQIIPSVAGCWYSKLIRK