traD

Coupling protein TraD

738 amino acids

Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell. It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations. Couples the transferosome to a type IV secretion system. Probably forms a pore through which single-stranded plasmid DNA is transferred to the secretion system. Plasmid specificity is conferred by the TraD-TraM pair (By similarity).

Belongs to the TrwB coupling protein family.

83.901 kDa

MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILIGLVLWVKISWQTFINGCIYWWCTSLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMIWCGEQLWSAFVLASVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVARMLKKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARQRGDMVVIYDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDPFWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIEKTAISIRAVLTNYVKAIRYLQGIEHNGDPFTIRDWMRGVREDQKNGWLFISSNADTHASLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCYVFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQYSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQARPKVAPEFIPRDINPEMENRLSAVLAAREAEGRQMASLFEPEVASGEDVTQAEQPQQPQQPQQPQQPQQPQQPQQPQQPQQPVSSVINDKKSDAGVSVPAGGIEQELKMKPEEEMEQQLPPGISESGEVVDMAAYEAWQQENHPDIQQHMQRREEVNINVHRERGEDVEPGDDF

traD

Coupling protein TraD

717 amino acids

Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell. It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations. Couples the transferosome to a type IV secretion system. Probably forms a pore through which single-stranded plasmid DNA is transferred to the secretion system. The last 37 residues are important for determining plasmid specificity and transfer efficiency, with additional specificity conferred by the TraD-TraM pair.

Belongs to the TrwB coupling protein family.

81.489 kDa

MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILVGLVLWIKISWQTFVNGCIYWWCTTLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMIWCSEQLWSAFVLAAVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVARMLKKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARQRGDMVVIYDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDPFWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTYLRNSPAANLVEEKIEKTAISIRAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHASLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCYVFGIQSYAQLEDIYGEKAAASLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQYSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQTRPKVAPEFIPRDINPEMENRLSAVLAAREAEGRQMASLFEPDVPEVVSGEDVTQAEQPQQPVSPAINDKKSDSGVNVPAGGIEQELKMKPEEEMEQQLPPGISESGEVVDMAAYEAWQQENHPDIQQQMQRREEVNINVHRERGEDVEPGDDF

traD

Protein TraD

129 amino acids

To plasmid IncP-alpha RP4 TraD.

13.601 kDa

MNEQTTTNTAAHDEPLAVLPPVDDDAAGREAVREKMADALTPGFQVEFDPDEAERVGAFVEDALSEQDAAASGDDLVEVDGALEPAFLDDEGPSADIPPFITTTNARELYDLRPGETVAQAAARKASEG

traD

Protein TraD

87 amino acids

To plasmid R751 TraD.

9.219 kDa

MNDPKTVQQDDFAPFDDTANAAAALREKLADAMTPGFQVEFDPEEAEKAGAFPEDALSEQDAAESDIDLVDATVPEDTTTAAANDGR

traD

Conjugal transfer protein TraD

71 amino acids

Belongs to the TraD family.

7.842 kDa

MAKSMTSNARKKDTREKIELGGLIVKAGLRYEKRALLLGLLVDGGRRLKGDEEERSRLTAIGAEAFGHDDE

traD

Conjugal transfer protein TraD

71 amino acids

Belongs to the TraD family.

7.885 kDa

MSKAMTSDARKKDTREKIELGGLIVKAGLRYEKRALLLGLLIDGERRLKGDEDERSRLTAIGVEAFGHDGE

traD

Probable conjugal transfer protein TraD

71 amino acids

Belongs to the TraD family.

7.773 kDa

MARSATSDARKKDTREKIELGGLIVKAGLRYEKRVLLLGALVDLSRRLNSDESERARLIAIGAEAFGDDGE