About Products Protein Database Contact

tpma

Gene
tpma
Protein
Tropomyosin alpha-1 chain
Organism
Danio rerio
Length
284 amino acids
Function
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Similarity
Belongs to the tropomyosin family.
Mass
32.723 kDa
Sequence
MDAIKKKMQMLKLDKENALDRAEQAETDKKAAEERSKQLEDDLVALQKKLKATEDELDKYSEALKDAQEKLELAEKKATDAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNEGKCSELEEELKTVTNNMKSLEAQAEKYSAKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI