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tnfaip8l2a

Gene
tnfaip8l2a
Protein
Tumor necrosis factor, alpha-induced protein 8-like protein 2 A
Organism
Danio rerio
Length
186 amino acids
Function
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).
Similarity
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Mass
21.355 kDa
Sequence
MEAFSSKDMAMQAQKKILSRMASKSVAQMFIDDNSSEVLDELYRVSKEHSGNRAEAQKVVKNMIKIAVKVGVLFRHEKFSAEELSIAQEFRKKLHHGAMTAISFQEVEFTFDKSVMINLLSDCRDLLLKLVEKHLTPKSLDRIRHVFNHYSNPELLTHLYDPQGNLWSNLSKICSGLNRMIEEGKL