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tmem33

Gene
tmem33
Protein
Transmembrane protein 33 homolog
Organism
Dictyostelium discoideum
Length
290 amino acids
Similarity
Belongs to the PER33/POM33 family.
Mass
33.485 kDa
Sequence
MSSPKFDSYDWENDPNWKEFTGTSTSINKLKEEYFKKNIDPNYKSSNNTTTQRPSTSSSSRTSSSSTSSPRATRAKPTFRRFLYGAWVIAQISVILFTLFYFISGNPYFFYKALLGATIAYSIPIFNTFEGRKPDRALAAQLVQDENAQFVFYCMIFYFFGSSSLVYLLPNFIYSFFHMLKIVIPYTSSVPFIKNLLEKVNSTNAKAIDFAISVEINIVLIAFFGIFSSFSNILLVFIYFRYLKLRYQFSQKIKSKINEYSQMVDQLSAHPSCPTFIRNIIPKIKMVLSR
Protein
Transmembrane protein 33 homolog: tmem33

Gene
TMEM33
Protein
Transmembrane protein 33
Organism
Homo sapiens
Length
247 amino acids
Function
Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules (PubMed:25612671). Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling (PubMed:26268696).
Similarity
Belongs to the PER33/POM33 family.
Mass
27.978 kDa
Sequence
MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDARGSNSLPLLRSVLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRTLFNELRIVVEHIIMKPACPLFVRRLCLQSIAFISRLAPTVP
Protein
Transmembrane protein 33: TMEM33

Gene
Tmem33
Protein
Transmembrane protein 33
Organism
Mus musculus
Length
247 amino acids
Function
Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling.
Similarity
Belongs to the PER33/POM33 family.
Mass
28.031 kDa
Sequence
MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSFLDKLSTNQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRNLFNELRIVVEHIIMKPSCPLFVRRLCLQSIAFISRLAPTVA
Protein
Transmembrane protein 33: Tmem33

Gene
Tmem33
Protein
Transmembrane protein 33
Organism
Rattus norvegicus
Length
247 amino acids
Function
Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling.
Similarity
Belongs to the PER33/POM33 family.
Mass
27.983 kDa
Sequence
MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSVLDKLSTNQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRNLFNELRIVVEHIIMKPSCPLFVRRLCLQSIAFISRLAPTVA
Protein
Transmembrane protein 33: Tmem33