Protein
Transmembrane protein 17A
Organism
Xenopus tropicalis
Function
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
Similarity
Belongs to the TMEM17 family.
Sequence
MAQAAGVRRQLDSLTRNIFLRDVGRTVPEKSGAPLTGDSEVAPSVSLQIFLYFNAFYFPFWWVCYVIMLQLKYVLLPDYYKFILVVLLILMSVIEVIRLYLGYSGNLQEKVPELAGFCLLSILLQLPLLLFLLCDPGLEPLPLERAVHGILTAFLLIQIPISIFALRKATRHLAGRFHLLGDLDGRA