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tif451

Gene
tif451
Protein
Eukaryotic translation initiation factor 4E-1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
218 amino acids
Function
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Similarity
Belongs to the eukaryotic initiation factor 4E family.
Mass
24.958 kDa
Sequence
MQTEQPPKESQTENTVSEPQEKALRTVFDDKINFNLKHPLARPWTLWFLMPPTPGLEWNELQKNIITFNSVEEFWGIHNNINPASSLPIKSDYSFFREGVRPEWEDVHNKTGGKWAFQNKGRGGNALDEMWLTTVLAAIGETLDPTGQEVMGVVINMRKGFYRLAVWTKSCNNREVLMEIGTRFKQVLNLPRSETIEFSAHEDSSKSGSTRAKTRMSV