thiN

Gene

thiN

Protein

Thiamine pyrophosphokinase

Organism

Bacillus subtilis (strain 168)

Length

214 amino acids

Function

Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate.

Similarity

Belongs to the thiamine pyrophosphokinase family.

Mass

24.099 kDa

Sequence

MKTINIVAGGPKNLIPDLTGYTDEHTLWIGVDKGTVTLLDAGIIPVEAFGDFDSITEQERRRIEKAAPALHVYQAEKDQTDLDLALDWALEKQPDIIQIFGITGGRADHFLGNIQLLYKGVKTNIKIRLIDKQNHIQMFPPGEYDIEKDENKRYISFIPFSEDIHELTLTGFKYPLNNCHITLGSTLCISNELIHSRGTFSFAKGILIMIRSTD

Protein

Thiamine pyrophosphokinase: thiN

Gene

thiN

Protein

Thiamine-phosphate synthase ThiN

Organism

Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

Length

190 amino acids

Function

Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

Similarity

Belongs to the ThiN family.

Mass

21.149 kDa

Sequence

MMIMEIENVRRALEMISSAEDFGILIPEVRSNIVMARSNPCGPEDVVAVPGRITEFQGRAFACRDPEYGASSHMARFIIALNEHLPGRRSALNIKFDESIISICEDMGLVVSSYDRSREPDSVRDTEGGSIPWGVEEALRNSESPPDVIYHRGAWGKEPMIVLTGRDAVEVAELAIKILRKYKSLKGDTR

Protein

Thiamine-phosphate synthase ThiN: thiN