thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella oneidensis (strain MR-1)

Length

721 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

79.501 kDa

Sequence

MSSLESSSESIAVNILGQTNRRVARAQAQAFIDTLKPLQHPNSQKLYLQGSRADLRVGMRQILQTDTRIGGRAAAPNVEKNPPIPVYDCAGPYSDPAAQINVRQGLAKLRLPWIIERQDTEVLDCTTSDFTQQRLKDDGLDHLRFEAGSSAIIRPRRALPGKRVSQLHYARQGIITPEMEYVAIRENMALADVQDEILNRRGQGESFGAVIGKPITPEFVRDEIARGRAIIPLNINHPEAEPMTIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEHLTWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLSHHQENFLYTHFREICELCVAYDVSLSLGDGMRPGSIADANDEAQFAELETLGELVNIAWEYDVQTIIEGPGHIPMQLIKENMDKQLIHCAEAPFYTLGPQITDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKQDVKQGLIAYKIAAHAADIAKGHPGAQIRDNALSKARFEFRWEDQYNLGLDPDTARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQDVRDYAASLEADAKAQSLAAETDGALAPLGSVQQVKSGHSELSHIDAELNYIAVKTQDELTAAMAQKSAEFAALGAKLYLPLDNANAANELAKHKDGAKLQSKTQVAKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)

Length

712 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

78.31 kDa

Sequence

MSSSNQNLAIAANAIDITAPESTIPNKSKVPNKSAESSQSTVPKAPSRREIRAQAQAFIDTLAPLQHTNSQKVYLEGSSADIRVGMRQILQTDTLVGGTDDAPIMEKNPPIRVYDCAGPYSDPEADINVRLGLVKLRQNWILARKDTEQLPCATSDFTQQRLADDGLDHLRFEAGSSAIVRPRRALQGKRVSQLHYARQGIITPEMEYVAIRENMALAEVQDEILNRKAKGEAFGALVGEPITAEFVRAEVARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLSHHKENFLYSHFREICELCVAYDVSLSLGDGMRPGSIADANDAAQFAELETLGELVKIAWEYDVQTIIEGPGHIPMQLIKENMDKQLAHCGEAPFYTLGPQITDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKQDVKQGLIAYKIAAHAADVAKGHPSAQIRDNALAKARFEFRWEDQYNLGLDPETARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQDVRAYAAGLEAAQTKAEQVEAAAQAMQVTIKTPQELEAAMALKSAQFAASGAEIYQVIDKHVKDKLVAEAEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodopseudomonas palustris (strain BisB18)

Length

709 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

76.662 kDa

Sequence

MNIRSNPDTTLPAVTTGPLPSSRKIFATPDEAPELRVPLREIILSDGAGEPNLPVYDTTGPYTDPSVTIDVNAGLSRIRTAWVKERGGVEEYQGRDVKPEDNGNVGAAHAAKSFTAYHKPLRGLDAPAAGTANSPPPRGEGSGVGGATNTVPSSTPLPTPPPQGGREQGIAYACGPHLPPMVTQLEFARAGIITKEMIYVATRENLGRKQQLARAEAALADGESFGASVPAFVTPEFVRSEIARGRAIIPANINHGELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNAPIPIGTVPIYQALEKCEGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRLAYIHLTANRTTGIVSRGGSIMAKWCLAHHQESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPLHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHASDLAKGHPAAQLRDDALSRARFDFRWQDQFNLGLDPDTAQAFHDETLPKDAHKVAHFCSMCGPKFCSMKITQDVRDYAAGLGDNEKAALNLAGGSSLGSVGMSISGKLEDGLPADAFAKAGMAEMSEKFRTMGEQLYLDAEKVKESNKALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Psychrobacter arcticus (strain DSM 17307 / 273-4)

Length

691 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

76.921 kDa

Sequence

MTISDIGSQASTTTSSKATAKADALKTPAHRSETDARFEEDARDLHRILPASRKVYIEGSRPDIQVPMREITLDPTPIQGVPESEWEQNPPFYVYDTSGVYTDPNTTIDLTKGLPKLREEWIKERGDTEQLSGLSSDYGQARARDISTANLRFAHIDKPRRAKAVDGKVGNVTQMHYARRGIITPEMEYIAIRETQKQHELTDMRQHEGETFGAHTPAIITPEFVRSEVAAGRAIIPNNINHPESEPMIIGRNFLVKINANIGNSALGSSIDEEVSKMTWATRWGADNIMDLSTGNHIHETREWLIRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHKESFLYTHFEDICEIMKQYDVAFSLGDGLRPGCLQDANDEAQFGELRTLGELTQVAWKHDVQVMIEGPGHVAMNRIKENMDLQLETCADAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQARDNALSKARFEFRWDDQFNLALDPDTAREFHDETLPKDAHKSAHFCSMCGPKFCSMKITQNVRDYAAGLKTLADTKNSVSPQSGALNDAEHLIKKVDTQLVEQVGSASAEEIHQGMAEMTEKYHKEGRQLYKEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)

Length

686 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

76.427 kDa

Sequence

MSSRRETRASAQTFIENLKPLQHPNSEKVFLSGSRPDLRVGMRQIHQTDTLHAKTNGETLREQNPPIMVYDCAGAYSDPNADINVHAGLEKFRQSWIEERQDTELLKGVSSQFTQQRLADDGLDHLRFDALVKPRRAKAGRCVTQMHYARRGIITPEMEYIAIRENMAREHVPEGVLTQKSAGESFGACIGEPITAEFVRSEVARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLNWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKESFLYEHFREICELCAAYDVSLSLGDGMRPGCIADANDEAQFAELETLGELVKIAWEYDVQTIIEGPGHVPMHLIKVNMEKQLEHCDEAPFYTLGPQTTDIAPGYDHFTSGIGAAQMAWYGCAMLCYVTPKEHLGLPNKEDVKQGLIAYKIAAHAADIAKGHPGAQVRDNALSKARFEFRWEDQYNLGLDPDTARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQEVREYAADQEAKALLAQAPLAQANIQDVELISPDEYKARQATEADLAKAMAQKSAEFKSQGSALYHSIDSSGINDNKNDQQDASVVRVPSLEIEG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella loihica (strain ATCC BAA-1088 / PV-4)

Length

683 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

76.178 kDa

Sequence

MSTRREMRAEAQAFIDNLKPLQHPNSQKFYLNGSRPDLKVAMRQIYQSDTLIGGTAEAPVYEKNPPITVYDCAGPYSDPEADIDVRRGLVKLRSEWIAERSDTQELEQVSSGFTQQRLADEGLDHLRFEQLPKPRRALEGRVVTQMHYARRGIITPEMEYVALRENMARETVTEEVLNQRAPGESFGAKLGEPITPEFVRQELAAGRAILPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLYEHFDEICQLCAAYDVSLSLGDGMRPGSIADANDEAQFAELETLGELVKKAWQYDVQTIIEGPGHIPMQLIKENMDKQLELCDEAPFYTLGPQTTDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKEDVKQGLIAYKIAAHAGDVAKGHPGAQIRDNALSKARFEFRWEDQYNLGLDPDTARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQEVREYAAAQATDVREIEVEQIDVTASAPKADIQQGMAQMSAQFKQSGSELYHSAIRQSPGVESTSLESTSLESTVLESTSLESTALEKAKEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Yersinia pestis

Length

681 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

75.878 kDa

Sequence

MSNNTTSLPAENSSHPRKGTPIRKKQREEAQQFINTLQGVTFPNSQRIYLQGSRPDIQVPMREIQLSPTQIGGSKNEPRYEDNEAIPVYDTSGPYGDPQAKLDVHNGLPKLRAAWVADRQDTEALASVSSGFTQQRLADEGLDHLRFEHLPRPRKAATGQCVTQLHYARQGKITPEMEFIALRENMGRERIRGEVLLQQHPGQAFGAHLPENITAEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGVAENLTWEMFRDTLLEQAEQGVDYFTLHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICQICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPATARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQEQAAAQAQAATPTTAAQPIDITQPINMLQSGMEKMSAEFRSRGSELYHRPANLSAEANNEPT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Yersinia pseudotuberculosis serotype I (strain IP32953)

Length

681 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

75.878 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)

Length

667 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

74.607 kDa

Sequence

MSNRRETRAQAQQFIDNLKPLQHPNSEKVYLEGSRPDLKVGMRQIHQSDTLVAGDEANPVFEANPPLKVYDCAGAYSDPDANIDVRKGLEKFRENWIEERGDTVQLTSASSGFTQQRLADDGLDHLRFESLLPPRRAKEGKRVTQLHYARQGIITPEMEYIAIRENMAKSEVTDPILTQKDKGESFGAVIGEPITAEFVRQEIARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLNWETFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLYEHFREICEICAAYDVSLSLGDGMRPGSIADANDEAQFSELETLGKLVKVAWEYDVQTIIEGPGHIPMNLIKENMDKQLEVCDEAPFYTLGPQTTDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKDDVKQGLIAYKIAAHAGDVAKGHPSAQIRDNALSKARFEFRWEDQYNLGLDPETARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQEVRDYAAAQEREAEARVIDIKSATEYDSYTGSESDTAKRASQREQGMAQMSAEFKAKGAELYHEASHKQPDVALED

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

Length

666 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.751 kDa

Sequence

MNIRSNPETTRAAVTTGALPSSKKIYATPASAPDLRVPLREIILSEGAGEPNLPVYDTSGPYTDPTVVIDVNKGLPRPRTEWVKQRGGVEQYQGRDIKPEDNGNVGAAHAAKAFTAHHQPLRGLDSPPPRGEGSGVGGATPAAFARGADHPPMITQYEFARRGIITKEMIYVAERENLGRKQQLERAEAALADGESFGAAVPAFITPEFVRDEIARGRAIIPANINHGELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCEGDPVKLTWELYKDTLIEQAEQGVDYFTIHAGVRLQYIHLTASRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWAKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWQDQFNLGLDPDTAQAFHDETLPKDAHKVAHFCSMCGPKFCSMKITQDVRDYAAGLGDNEKAALYPVGHAGMTISGTIEDGMAQMSAKFKEMGSSVYLDAEKVKESNKALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

Length

664 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

74.141 kDa

Sequence

MSTEPLSINPLSAKPLSATQEPSTSSKPSRREQRAAAQRFIETLQGTAFPNSKRIYLTGSRDDIGVPMREIQLSPTLLGGSKDDPQYEPNEPIPVYDTSGPYGDPAAQPDVHVGLAKLRANWIAERHDTEALSGVSSDFTQQRMADAGLDHLRFEHLPRPLRAKAGKRVTQLHYARQGMITPEMEFIAIRENMGRERIRGEVLRQQHPGQSFGALLPENITPEFVRQEVAAGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGVAENLNWEMFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKESFLYEHFREICEICAAYDVALSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPQTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAKQETEAKPIEIGMAEMSQEFRSRGSELYHSATSLQAEESK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)

Length

664 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

74.154 kDa

Sequence

MSNRRETRKAAQDFIDNLKPLRRPNSEKIFIEGSRPDIQVGMRQIHQTDTRIVNTRGEETFEANPPIKVYDCAGPYSDPNADINVRRGLPKLREGWILARSDTEELNSASSNFTQQRLADDGLDHLRFDVLPKPRRAKAGKRVTQLHYARQGIITPEMEYIAIRENMARDEVTDEQLNRKKPGEAFGALVSKPITPEFVRDEVARGRAIIPANINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIVRNSPVPIGTVPIYQALEKVNGIAEDLNWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLSHHQENFLYTHFRDICELCAAYDVSLSLGDGMRPGSIADANDEAQFAELETLGELVKIAWEYDVQTIIEGPGHIPMQLIKENMDKQLEHCAEAPFYTLGPQTTDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKEDVKQGLIAYKIAAHAADVAKGHPGAQIRDNALSKARFEFRWEDQYNLGLDPDTARAYHDETLPQESAKVAHFCSMCGPKFCSMKITQDVRDYAASLENAARSEADSVQTLEVGAAESYSKAESYARAGMDKMSATFKQTGSALYSETHVEAALSTEKEPV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella halifaxensis (strain HAW-EB4)

Length

662 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

74.114 kDa

Sequence

MSNRRETRAQAQQFIDNLKPLQHPNSEKIYLQGSRADLKVGMRQIHQADTLIGGNETNPVFEANPPLKVYDCAGAYSDPDANIDVRKGLEKFREHWIEERGDTEQLAGVSSGFTQQRLADDGLDHLRFESLLPPRRAKTAKRVTQLHYARQGIITPEMEYIAIRENMALAEVNDPILTQKDKGESFGAVIGEPITPEFVRQEVARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGIAEDLNWETFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLYEHFRDICEICAAYDVSLSLGDGMRPGSIADANDEAQFSELTTLGELVKIAWQYDVQTIIEGPGHIPMNLIKENMDKQLELCDEAPFYTLGPQTTDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAGDVAKGHPSAQIRDNALSKARFEFRWEDQYNLGLDPDTARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQEVRDYAAAKERDELANNIDIKSDAEYQSCADSETTSERELGMAQMSAEFKAKGAELYHEAADKQRDAVLED

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681)

Length

658 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

74.19 kDa

Sequence

MNNSTDAVNPAKKPQTRREKREAAEAFLKNVSDQSFPNSKKVYVQGEIHDIKVGMREITLSDTLVSGSKDKPVYEKNEPLCVYDTSGFYTDENVEIDVHKGIPRLRETWIDARDDVETFTSTHSEFAQQRLDDEGVDEIRFEHLPKMRIAKKGKNVTQMHYARQGIITPEMEYIAIRENLKREEVKDATLLLQHKGQSFGASIPEQITPEFVRDEVARGRAIIPVNINHPECEPMIIGRNFLIKVNANIGNSAVTSSIEEEVEKLVWSTKWGADTVMDLSTGRNIHETREWIMRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEILKQYDVSFSLGDGLRPGSVADANDEAQFAELHTLGELTKIAWKHDVQTIIEGPGHVPLHMIKENMEEQLEHCGEAPFYTLGPLTTDIAPGYDHITSGIGAANIGWYGCAMLCYVTPKEHLGLPNKEDVKEGLMTYKIAAHAGDLAKGHPGAQIRDNAMSKARFEFRWYDQFNIGLDPERARTYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAANLDKNAIKIQLLDETITLTSDEAIERAMQEKSAEFKATGSEIYQLAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)

Length

652 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.061 kDa

Sequence

MVSRTDRSSSSTSKAVTSSPSTSSLSSAASSPSVSSSSSSSSVSAAGMTAVSTGPLTGSRKTWLVGADPDLRVPMREIVLTTGDTVVVYDTSGPYTDPGVTIDVRRGLPATRDSWIAQRGDTAPDERRTVPGTGASGPGTLGSGTPGSGTPGSGPLGLGGTDLDGRVRVPRRAVPGRPSITQLGYARRGQITREMEFVALREGLPVETVRAEIAAGRAVLPANVNHPESEPMAIGRAFLVKINANLGNSAVTSSIEEEVEKMVWATRWGADTVMDLSTGSDIALTREWIIRNAPVPVGTVPIYQALEKVGGRPEKLSWEVYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTARRRTGIVSRGGSILASWCLAHHEENFLYTHFAELCEIFAAYDVTFSLGDGLRPGSIADANDEAQLAELATLGELTQVAWEHDVQVMIEGPGHVPMNKIEENVQLQRELCHDAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWAGTAMLCYVTPKEHLGLPDRDDVKAGVIAYKIAAHAADLAKGHPGAQAWDDALSDARFEFRWADQFHLALDPDTARAFHDETLPAPAAKSAHFCSMCGPHFCSMKISHQVRAHAGGDGLDPAGHGADPAGDEAVTAGLREKAAEFNAAGNRIYLPVANS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella sediminis (strain HAW-EB3)

Length

652 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.762 kDa

Sequence

MSTRRETRAQAQQFIDNLKPLQHPNSEKVYLVGSRDDIRVGMRQIHQSETMIGGTESHPVLESNPPLKVYDCAGPYSDPNAKINVREGLDKFRANWILERNDTEQLIAASSGFTQQRLADYGLDHLRFDSLLSPRKAKQGQCVTQLHYARQGIVTPEMEYIAIRENMALSEVTDEALTQKAEGESFGAAISQPITPEFVRQEVARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHLENFLYEHFRDICELCAAYDVSLSLGDGMRPGSIADANDEAQFSELETLGELVKIAWEYDVQTIIEGPGHIPMNLIKENMDKQLEVCDEAPFYTLGPQTTDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAGDVAKGHPTAQIRDNALSKARFEFRWEDQYNLGLDPDTARAYHDESLPQESAKVAHFCSMCGPKFCSMKISQEVREYAAAQEVKLHTDTEFKAKSVKESGMAQMSAEFKAKGAALYHESGALVEDVELVETEG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shewanella woodyi (strain ATCC 51908 / MS32)

Length

652 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.479 kDa

Sequence

MSNRRQTRAQAQQFIDTLTPLQHPNSEKVYLTGSREDLRVGMRQILQSDTLVGGTEADPILESNPPLKVYDCAGPYSDPDAEINVRAGLNKFRQSWIEERADTEQLAGVSSGFTQQRLADDGLDHLRFDSLLPPRRAQSGKRVTQLHYARNGIITPEMEYIAIRENMEQAGITDPVLRQKAKGESFGASIEQVITPEFVRQEVARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLSWEVFRDTLVEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLSHHSENFLYEHFTEICELCAAYDVSLSLGDGMRPGSIADANDEAQFSELETLGELVKIAWEYDVQTIIEGPGHIPMNLIKENMDKQLALCDEAPFYTLGPQTTDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKEDVKQGLIAYKIAAHAGDVAKGHPTAQIRDNALSKARFEFRWEDQYNLGLDPETARAYHDESLPQESAKVAHFCSMCGPKFCSMKISQEVRDYAASQEVELQSHASYQAKSASEIETGMAQMSAEFKAKGAELYHETAVVDEELADAEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thiobacillus denitrificans (strain ATCC 25259)

Length

652 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.258 kDa

Sequence

MNAAIPNQAAKFLAATAHVDEAAVQPLPNSRKIYVEGSTPDIRVPMREIRQADTPLMFSGEAGTGAERSEPNPPIFVYDCSGPYTDPAAKIDIREGLPALRTKWIEARGDTEVLRDLSSEYGRQQAANPELATMRFPGLHRHPRRAKAGMNVTQMHYARQGIITPEMEFIAIRENNNRAAYLESLRASGPQGAKLAALMSRQHPGQNFGANLQGEITPEFVRDEVARGRAIIPNNINHPESEPMIIGRNFLVKINANIGNSALGSSIQEEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEMFRDTLVEQAEQGVDYFTIHAGVLLRYVPMTANRMTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICEIMKAYDVAFSLGDGLRPGSIYDANDEAQLSELRTLGELTQVAWKHDVQVMIEGPGHVPMQLIKENMDIQLESCSEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWDDQFNLGLDPDKAKSFHDETLPKESAKVAHFCSMCGPHFCSMKITQDVREFAAKEGLNEADALARGMEVKAVEFVKQGAEVYRKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudoalteromonas haloplanktis (strain TAC 125)

Length

650 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

73.314 kDa

Sequence

MSNTAKKSSRRETRAAASEYIYNLTGQPFPNSHKVYVEGTQNNIRVGMREITLSDTYIGGSDENPVYEPNEPLRVYDTSGPYTDPNFKLDVRQGLAKFREQWIESRGDTELLESVTSRFTQQRMADEGLDHLRFEHLPKIRRGKAGKNVTQMHYARQGIITPEMEYVAIRENMGRKKIHAELLAAQHKGESFGASIPDFITPEFVRDEIARGRAILPNNINHPETEPMIVGRNFLVKVNANIGNSSVSSSIEEEVEKMVWSTRWGADTVMDLSTGRYIHETREWVVRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEILKQYDICFSLGDGLRPGSIADANDEAQFSELRTLGELTKLAWKHDVQVFIEGPGHVPMHMIKANMDEQLKHCDEAPFYTLGPLTTDIAPGYDHITSGIGAAQIAWYGCAMLCYVTPKEHLGLPNKEDVKEGLITYKIAAHAADLAKGHPGAQERDNALSKARFEFRWHDQFNIGLDPERAREYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDLEARGIDPANAADTITIKMIDVEAQMKAKSDEFKKTGSEIYHKAI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio tasmaniensis (strain LGP32)

Length

649 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

73.038 kDa

Sequence

MSSRKQARLEAKNFIDSLSVQPYPNSKKAYIQGSREDIQVPVREISLADSLVGGTKKEPVFEPNVPIQVYDTSGVYTDPTHQIDLYSGLPKLREQWIDERGDTELLDDVSSVYTKERLEDETLDDLRYGNLPRIRRATDEQCVTQLHYARQGIITPEMEYIAIRENMGRQKFADEQLNHQHPGHNFGANLPKEITPEFVRKEVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSSVSSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAEDLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSIADANDEAQFSELRTLGELTKVAWEYDVQVIIEGPGHVPMHLIKENMDEQLEHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLALDPETARSFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDTEQVAADQAIEIKMLDNPLEGMRQKSQEFRDTGSELYHPAVGAKEAQLEE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)

Length

648 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.753 kDa

Sequence

MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSEYGRERAADPATAELRFPDLHRHPRRAKAGRNVTQMHYARQGIITPEMEFIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANEAGTNMLTEITPEFVRSEVACGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGMSEDDALKKGMEVKAVEFVKTGSEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Aliivibrio salmonicida (strain LFI1238)

Length

648 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.712 kDa

Sequence

MSSSRKQARLDAKSNIESLSVQPYPNSKKIYIDGSRPDIRVPMREISLADSLVGGTKENPTLIPNEPIQVYDTSGVYTDPNYDIDVYQGLPKLRERWIEDRTDTEMLKGVSSVYSQERLSDETLDELRYGNLPTIRRAKKGQCVTQLHYARQGIITPEMEYIAIRENMGRQKFADEQLNHQHPGHSFGANLPKEITPEFVRNEVAEGRAIIPANINHPEAEPMIIGRNFLIKVNANIGNSSVSSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVSLSLGDGLRPGSIADANDEAQFAELRTLGELTKVAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKIGLITYKLAAHAGDLAKGHPGAQIRDNALSKARFEFRWEDQFNLSLDPITAREFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDTEQVALDQAINIKMLDDPLEGMRQKSAEFKASGSELYHPAVDAEPVKS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio vulnificus (strain CMCP6)

Length

647 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.427 kDa

Sequence

MSNRKQARLEAKQFIDTLSVQPYPNSTKVYVEGSRSDIRVPMREISLADSLVGGTKEAPIFQPNEAVRVYDTSGVYTDPTHQIDLYNGLPKLREEWIAERADTEVLDDVSSVYTKERLEDETLDELRYGNLPRIRRAKAGYCVTQLHYARKGIITPEMEYIALRENMGRAKYQDEVLTQQHAGQSFGANLPKEITPEFVRREVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSSVTSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLTWEVMRDTLIEQAEQGVDYFTIHAGLLLRYIPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTKIAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLSLDPDTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKGQQGEAGQAIEVKLLDDPLEGMKQKSAEFKASGSELYHPAVSHEEVAEG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio vulnificus (strain YJ016)

Length

647 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.427 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodopseudomonas palustris (strain HaA2)

Length

646 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.805 kDa

Sequence

MNIRSNPDTTRPAVTTGGLPSSRKIYAVPATAPDLRVPLREIMLSEGAGEPNLPVYDTSGPYTDPGVTIDVNKGLSRARTEWVKQRGGVEQYEGRDIKPEDNGNVGAAHAAKSFTAHHQPLRGVGDAPITQYEFARKGIITKEMIYVAERENLGRKQQLERAEAALADGESFGAAVPAFITPEFVRDEIARGRAIIPANINHGELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCDGDPVKLTWELYKDTLIEQAEQGVDYFTIHAGVRLQYIHLTADRVTGIVSRGGSIMAKWCLAHHQESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWAKGCQVMIEGPGHVPLHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLGKGHPAAQLRDDALSRARFDFRWQDQFNLGLDPDTAKAFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAAGLGDNEKAALNLAGAGSFGSVGMTMSGVIEDGMAQMSEKFRDMGEKLYLDAEKVKESNKALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)

Length

646 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.097 kDa

Sequence

MNIRSNPDTTRPAVTTGALPSSRKMFSAPDAAPDLRVPLREILLSEGAGEPNLPVYDTSGPYTDPNVIIDVNAGLPRTRLAWVKERGGVEEYDGREIKPEDNGNVGASHAAAAFKAHHKPLRGIGDAPITQLEFARAGIITKEMIYVAERENLGRKKQLERAEAALADGEAFGASVPAFITPEFVREEIARGRAIIPSNINHAELEPMIIGRNFLVKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCDGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRLPYIHLTADRVTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTQIAWKKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFDFRWQDQFNLGLDPDTAVAFHDETLPKDAHKVAHFCSMCGPKFCSMKITQDVRDYAATLGDNEKAALYPDTAPKANDAAGVPEPSYRDQGMKEMSARFKEMGGNVYLDAEKVKESNRVL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio campbellii (strain ATCC BAA-1116 / BB120)

Length

646 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.596 kDa

Sequence

MSSRKQARLEAKQFIDTLSVQPYPNSSKVYVEGSRPDIRVPMREISLADSLIGGTKEAPIFEPNEPVRVYDTSGVYTDPEHTIDLYNGLPKLREGWIEERSDTELLDEVSSVYTKERLEDETLDDLRYGNLPRIRRAKDGQCVTQLHYARQGIITPEMEYIALRENMGRAQYRDEVLNQQHPGQSFGANLPKDITAEFVRKEVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSSVTSSIEEEVEKLVWATRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVAISLGDGLRPGSVADANDEAQFAELRTLGELTKVAWEYDVQVIIEGPGHVPMHMIKENMEEQLEHCHEAPFYTLGPLTTDVAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKVGMITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLSLDPDTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDTEQVAADQAISIKMLDDPLEGMRQKSQEFRDTGSELYHPAAYAEVSD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

Length

646 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.477 kDa

Sequence

MSSRKQARLEAKQFIDTLSVQPYPNSTKVYIEGSRPDIRVPMREISLADSLIGGTKEAPIFEPNEPVRVYDTSGVYTDPDYAIDLYSGLPKLREGWIEERNDTEILEDVSSVYAKERLDDETLDDLRYGNLPRIRRAKAGKCVTQLHYARKGIVTPEMEYIALRENMGRAQYRDDVLTQQHPGQSFGANLPKDITAEFVRKEVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSSVTSSIEEEVEKLVWATRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGIAENLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSVADANDEAQFAELRTLGELTKIAWEYDVQVIIEGPGHIPMHMIKENMDQQLEHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKTGMITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLALDPDTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDTEQVAADQAISIKMLDDPLEGMRKKSEEFRATGSELYHPAVHAEADE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)

Length

645 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.476 kDa

Sequence

MSHNTVIPTTDISPKPDPARPRKAQRDAAQEFINSIQGVTFPNSRRIYLQGSRDDIQVPMREIQLSPTLIGGTKEEPQYEENEAIPVYDTSGAYGDPDAKLDVHVGLTQLRQPWIDERQDTEPVAALSSDFTQQRLTDAGLDHLRFNHRPHPLKARKDKRVTQLHYARQGIITPEMEFIALRENMGRERIRGDVLRQQHPGQSFGAQLPENITPEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSSVTSSIEEEVEKLIWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGGAENLTWEIFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHIPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPDTARAYHDETLPQASGKIAHFCSMCGPKFCSMKISQEVRDYAAGMEQMSEAFRAHGSELYHSVEDVSHEQSA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

Length

645 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.634 kDa

Sequence

MSNRKQARLEAKRFIDTLSVEPYPNSQKSYLLGSRPDIRVPVREITLSDTLVGGSKDAPIFEPNEPICVYDTSGVYTDPSHDIDLYKGLPKLREEWIEERRDTHILPSMSSHFARERLADETLDELRYGHLPRIRRAMGQHRVTQLHYARQGIITPEMEFVAIRENSRRLAHQDPSLLQQHAGQNFGAHLPDLITPEFVRREIAEGRAIIPCNINHPESEPMIIGRNFLVKVNANIGNSSVSSSIEEEVEKLVWATRWGADTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLTWEVMRDTLLEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLSHHQENFLYTHFREICEICAQYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTQIAWEYDVQVMIEGPGHVPMHLIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLALDPVTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYANNQTLDTTVIDLVMPAESIQLAMQDKSREFLASGAELYHPLVKEPIEE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

Length

645 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.634 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vibrio cholerae serotype O1 (strain M66-2)

Length

645 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.634 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Aliivibrio fischeri (strain ATCC 700601 / ES114)

Length

644 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.38 kDa

Sequence

MSSSRKQARLDAKTNIESLSVQPYPNSNKVYIEGSRPDIRVPMREISLADSLVGGTKESPIFEPNEPIQVYDTSGVYTDPSYDIDVYKGLPKLRQEWIEERNDTELLDGVSSVYSQERLADETLDELRYGNLPTIRRAKQGQCVTQLHYARQGIITPEMEYIAIRENMGRQKFADEQLNHQHPGHSFGANLPKEITPEFVRREVAEGRAIIPSNINHPEAEPMIIGRNFLIKVNANIGNSSVSSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSVADANDEAQFAELRTLGELTKVAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKTGLITYKLAAHAGDLAKGHPGAQIRDNALSKARFEFRWEDQFNLSLDPITAREYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDSEQVALDQAIEIKMIDDPLEGMRQKSEEFKASGSELYHPVVEAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Aliivibrio fischeri (strain MJ11)

Length

644 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.352 kDa

Sequence

MSSSRKQARLDAKTNIESLSVQPYPNSNKVYIEGSRPDIRVPMREISLADSLVGGTKESPIFEPNEPIQVYDTSGVYTDPSYDIDVYRGLPKLRQEWIEERNDTELLDGVSSVYSQERLADETLDELRYGNLPTIRRAKQGQCVTQLHYARQGIITPEMEYIAIRENMGRQKFADEQLNHQHPGHSFGANLPKEITPEFVRKEVAEGRAIIPSNINHPEAEPMIIGRNFLIKVNANIGNSSVSSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSVADANDEAQFAELRTLGELTKVAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKTGLITYKLAAHAGDLAKGHPGAQIRDNALSKARFEFRWEDQFNLSLDPITAREYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDSEQVALDQAIEIKMIDDPLEGMRQKSEEFKASGSELYHPAVEAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

THIC

Protein

Phosphomethylpyrimidine synthase, chloroplastic

Organism

Arabidopsis thaliana

Length

644 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.987 kDa

Sequence

MAASVHCTLMSVVCNNKNHSARPKLPNSSLLPGFDVVVQAAATRFKKETTTTRATLTFDPPTTNSERAKQRKHTIDPSSPDFQPIPSFEECFPKSTKEHKEVVHEESGHVLKVPFRRVHLSGGEPAFDNYDTSGPQNVNAHIGLAKLRKEWIDRREKLGTPRYTQMYYAKQGIITEEMLYCATREKLDPEFVRSEVARGRAIIPSNKKHLELEPMIVGRKFLVKVNANIGNSAVASSIEEEVYKVQWATMWGADTIMDLSTGRHIHETREWILRNSAVPVGTVPIYQALEKVDGIAENLNWEVFRETLIEQAEQGVDYFTIHAGVLLRYIPLTAKRLTGIVSRGGSIHAKWCLAYHKENFAYEHWDDILDICNQYDVALSIGDGLRPGSIYDANDTAQFAELLTQGELTRRAWEKDVQVMNEGPGHVPMHKIPENMQKQLEWCNEAPFYTLGPLTTDIAPGYDHITSAIGAANIGALGTALLCYVTPKEHLGLPNRDDVKAGVIAYKIAAHAADLAKQHPHAQAWDDALSKARFEFRWMDQFALSLDPMTAMSFHDETLPADGAKVAHFCSMCGPKFCSMKITEDIRKYAEENGYGSAEEAIRQGMDAMSEEFNIAKKTISGEQHGEVGGEIYLPESYVKAAQK

Protein

Phosphomethylpyrimidine synthase, chloroplastic: THIC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.662 kDa

Sequence

MNIRSNPDTTRPAVTTGALPSSRKIFSVPEAAPDLLVPLREIVLSEGAGEPNLPVYDTSGPYTDPDVTIDVNAGLPRTRLAWVKERGGVEEYDGRVIKPEDNGNVGASHAATAFKAHHKPLRGVGDAPITQLEFARAGIITKEMIYVAERENIGRKQQLERAEAALADGESFGAAVPTFITPEFVREEIARGRAIIPANINHAELEPMIIGRNFLVKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCDGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRLPYIHLTADRVTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTQIAWNKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNRDDVKTGVITYRVAAHAADLAKGHPAAQLRDDALSRARFDFRWQDQFNLGLDPETAVAFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLGDNEKAALYPEGSKLASGMTMKGVIEDGMTQMSEKFKEMGGQVYVEAEAVKESNKVL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.784 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPEAKIDIRAGLAALRQGWIDARGDTEVLGGLSSEYGLERAADPATADLRFPGLHRNPRRAQAGKNVSQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHPGQAFGAAAFGANAPAEITPEFVRSEVACGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia multivorans (strain ATCC 17616 / 249)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.075 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTETLPGLSSQYGRERAADPATADLRFPGLHRNPRRARAGKNVTQMHYARQGIITPEMEFIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHPGQAFGAAAFGGNAPSEITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSEADALQKGMEVKAVEFVKSGSEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia mallei (strain NCTC 10247)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.14 kDa

Sequence

MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLSGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia mallei (strain NCTC 10229)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.14 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia mallei (strain ATCC 23344)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.14 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia mallei (strain SAVP1)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.14 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia pseudomallei (strain 1106a)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.124 kDa

Sequence

MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia pseudomallei (strain 1710b)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.124 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia pseudomallei (strain 668)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.124 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia pseudomallei (strain K96243)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.124 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia vietnamiensis (strain G4 / LMG 22486)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.077 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTEVLDGLSSGYGRERAADPATADLRFPGLHRNPRRAQAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLENLKASGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALQKGMEVKAVEFVKTGAEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia ambifaria (strain MC40-6)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.021 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQGWIEARGDTEVLDGLSSQYGLERAADPATADLRFPGLHRNPRRAQPGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia cenocepacia (strain AU 1054)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.13 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTEVLPGLSSQYGLERAADPATAELRFPGLHRNPRRAQPGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEIARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia cenocepacia (strain MC0-3)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.026 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQGWIEARGDTEVLPGLSSQYGLERAADPATADLRFPGLHRHPRRAQPGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia cenocepacia (strain HI2424)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.13 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.09 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTEVLPGLSSQYGLERAADPATAELRFPGLHRNPRRAQAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.035 kDa

Sequence

MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQGWIEARGDTEVLDGLSSQYGLERAADPATADLRFPGLHRNPRRAQPGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEIARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.205 kDa

Sequence

MNANPKFISANAHVDEAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTESLQGLSSEYGRERAADPATAELRFPGLHRTPRRAQPGKNVSQMHYAKQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHPGQAFGATAFGPNGLQEITPEFVREEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLEWCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKTGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVRDYAAKEGMSDADALKKGMEVKAVEFIKSGAEIYQRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.306 kDa

Sequence

MNANPKFLSADAHVDEAAVAPLPNSRKVYVTGSRADIRVPMREISQADTPDSFGGEKNPPVYVYDTSGPYSDPEAKIDIRAGLPALRQAWIEERGDTEALTGLSSDFSRERAADTATADLRFKGLHRTPRRAIAGKNVSQMHYARKGIITPEMEYIAIRENQRRAEYLESLKTSGPNGEKLAAMMGRQHPGQAFGASAFGPNGLTAITPEFVREEVARGRAIIPNNINHPESEPMIIGRNFLVKVNANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVAFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQTMIEGPGHVPMQLIKENMDLQLEWCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKTGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVTDDEALKKGMEVKSIEFMKKGAEIYQRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Paraburkholderia xenovorans (strain LB400)

Length

643 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.372 kDa

Sequence

MNANPKFLSADAHVDEAAVAPLPNSRKVYVTGSRPDIRVPMREISQADTPDSFGGEKNPPVFVYDTSGPYSDPEARIDIRAGLPALRQAWIEERGDTEALTGLSSDFGRERAADTATADLRFQGLHRTPRRAIAGKNVSQMHYARKGIITPEMEYIAIRENQRRAEYLESLKTSGPNGEKLAAMMGRQHPGQAFGASAFGPNGLTEITPEFVREEVARGRAIIPNNINHPESEPMIIGRNFLVKVNANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVAFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQTMIEGPGHVPMQLIKENMDLQLEWCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKTGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVTDDEALKKGMEVKSIEFMKKGAEIYQRQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

Length

642 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

72.006 kDa

Sequence

MSNRREQRQQAQQFINELAGEAYPNSTRHYESGSRDDIRVAMRLIHQHDSLVGGTEDNPILEPNPPIPVYDTSGPYGDPKENIDVHKGLSPLRKTWIEERSDTRELDGVSSSFAKERENDIFTEDFRFIRSRKPLKAKAGKNVTQLHYARQGVITPEMEYIAIRENMGRQAIKDAELTQQHKGEHFGANLPETITPEFVRQEVAAGRAIIPCNINHPELEPMIIGRNFLVKINANIGNSAVTSSIEEEVEKLVWSTRWGADTIMDLSTGRNIHETREWLLRNSPVPLGTVPIYQALEKVNGVAEDLTWEMFKDTLIEQAEQGVDYFTIHAGVLLEYVHLTAKRVTGIVSRGGSIMAKWCLSHHQQSFLYEHFNDICEICAKYDVALSLGDGLRPGSVADANDDAQFSELRTLGELTKIAWEYDVQVMIEGPGHVPMHMIKENMEEQLKHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPHTARAYHDETLPQASGKVAHFCSMCGPKFCSMKISQEVRDVAKQAENLAPAQAAEKEKEKGMKDMANAFNKSGAELYHTADSKVELP

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodopseudomonas palustris (strain BisA53)

Length

641 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.625 kDa

Sequence

MNIRSNPDTTRPAVTTGALPSSQKIYVTPDAAPDLRVPLREIILSKEAAEPNLPVYDTTGPYTDPAITIDVNAGLKRPRTQWVLERGGVEQYQGREIKPIDNGNVSGEHAAAAFKAYHQPLRGVGDSPITQYEFARKGIITKEMIYVATRENLGRKQQLERAEAALADGESFGAAIPAFITPEFVRDEIARGRAIIPANINHGELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNAPIPIGTVPIYQALEKCDGDPVKLTWELYKDTLIEQCEQGVDYFTIHAGVRLAYIHLTANRVTGIVSRGGSIMAKWCLAHHQESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPLHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHASDLAKGHPAAQLRDDAVSRARFDFRWQDQFNLGLDPDTAKAFHDETLPKDAHKVAHFCSMCGPKFCSMKITQDVRDYAAGLGDNEKAALYPAGHVGMTISGVIEDGMAQMSAKFRDMGEELYLDAEKVKESNRALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodopseudomonas palustris (strain BisB5)

Length

641 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.368 kDa

Sequence

MNIRSNPDTTRPAVTTGGLPSSKKIYATPAAAPDLRVPLREIILSEGAGEPNLPIYDTSGPYTDPSVTIDVNAGLSRARTQWVKERGGVEEYQGRDVKPEDNGNVGAAHAAKSFTAYHKPLRGIGDAPITQYEFARRGIITKEMIYVAERENLGRKQQLERAEAALADGESFGASVPAFITPEFVRDEIARGRAIIPANINHGELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCEGDPVKLTWELYKDTLIEQCEQGVDYFTIHAGVRLQYIHLTANRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWAKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHAADLAKGHPAAQLRDDAVSRARFDFRWQDQFNLGLDPDTAQAFHDETLPKDAHKVAHFCSMCGPKFCSMKITQDVRDYAAGLGDNEKAALYPAGSVGMSISGVIEDGMAQMSAKFRDMGEHLYLDAEKVKESNKALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodopseudomonas palustris (strain TIE-1)

Length

641 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.366 kDa

Sequence

MNIRSNPETTRAAVTTGALPSSKKIYATPASAPDLRVPLREIILSEGAGEPNLPVYDTSGPYTDPTVVIDVNKGLPRPRTEWVKQRGGVEQYEGRDIKPEDNGNVGAAHAAKAFTAHHQPLRGISDAPITQYEFARRGIITKEMIYVAERENLGRKQQLERAEAALADGESFGAAVPAFITPEFVRDEIARGRAIIPANINHGELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCEGDPVKLTWELYKDTLIEQAEQGVDYFTIHAGVRLQYIHLTASRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWAKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWQDQFNLGLDPDTAQAFHDETLPKDAHKVAHFCSMCGPKFCSMKITQDVRDYAAGLGDNEKAALYPVGHAGMTISGTIEDGMAQMSAKFKEMGSSVYLDADKVKESNKALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Corynebacterium jeikeium (strain K411)

Length

641 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.023 kDa

Sequence

MTDTSTQNTATPTDEYGAEIHPKHSFSPIEKTVESFGKTFTLEVPETEIQLDDSPTGPNEPVRIYRTRGPWAEPTKGLEGLRSEWIEARDDVEAYEGRRRNLLDDGNRAVKRGEASEEWKGSTRPTLRAKEGKRVTQMHYARQGIITPEMEYVALREHCDVEKVREQVASGKAIIPNNINHPESEPMIIGNAFTTKINANIGNSAVTSSIREEVDKLRWATRWGADTVMDLSTGNDIHTTREWILRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVRLPFVPLTTKRVTGIVSRGGSIMAGWCLAHHKESFLYENFDELCEIFAKYDVAFSLGDGLRPGSIADANDAAQFAELKTIGELTHRAWEYDVQVMVEGPGHVPLNMVQVNNEKEQEWCGGAPFYTLGPLVTDIAPGYDHITSAIGAANIAMGGTAMLCYVTPKEHLGLPNKDDVKTGVITYKVSAHAADVAKGHPGAHEWDDAMSKARFEFRWHDQFALSLDPDTAQAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDAFGDEIDEALATDQKQSLVKDLGLPGFGRQSVDGIDSLSAAGEEEMAEEFRRAGSQLYLNRDEAKEVAEDLQKEAAAHGER

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Photobacterium profundum (strain SS9)

Length

640 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.849 kDa

Sequence

MSIRKQARLEAKQFIDSLTVQPFPNSQKVYVQGSRADIQVPMREISLADSLVGGSKKAPILEPNEPIRVYDTSGFYTDPNQPVNIYDGLEKVRSGWIEERGDTVLLEQSNSVYTKERLSDETLDELRFDARIQARQAVEGHCVTQLHYARKGIVTPEMEYIAIRENMGRAKYADEELNQQHPGINFGANLPPEITPEFVRKEVAEGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVSSSIEEEVEKLVWSIRWGGDTVMDLSTGRNIHETREWIIRNSPVPIGTVPMYQALEKVNGVAENLNWDVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLAHHEESFLYMHFREICEICAQYDISLSLGDGLRPGSVADANDEAQFSELRTLGELTKIAWEYDVQVMIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAIIGWYGCAMLCYVTPKEHLGLPNKDDVKVGLITYKLCAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLGLDPDTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAKGLEENGDIAIKLLDNPLEGMQQKSDEFRSRGSELYHPVQEEI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Teredinibacter turnerae (strain ATCC 39867 / T7901)

Length

639 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.103 kDa

Sequence

MAANEKTYLSETAKVDQSSVQPFPNSSKIYVEGSRSDIRVPMREISLADTPTDFGGEQNRPVRVYDTSGPYTDPEVQIDLRTGLPDVRSRWINERGDTEALAEKSSLFATQRLNDPALASLRFQHLRTPRRAKSGANVSQMHYARQGIITPEMEYIAIRENMSLQQAREQGVLQEQHAGQAFGAAIPDEITPEFVRSEVARGRAIIPANINHPELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGTRWGADTIMDLSTGKNIHETREWIIRNASVPIGTVPIYQALEKVDGIAEDLTWDIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDEAQFGELETLGELTKIAWQHDVQTMIEGPGHVPMQMIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKEGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAYHDETLPKESAKVAHFCSMCGPKFCSMKITQEVRDYAAEHGTEITPRAPGEAEEVVRMVDVEAEMQKKSDEFRAQGSEIYSKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)

Length

638 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.443 kDa

Sequence

MTTDTLEKPRLSDTAQVDSQSIAPFPNSKKIYVQGSRPDIRVPMREINLSITPTEFGGEQNPPVRVYDTSGVYTDPNVKIDVRQGLPDVRSAWIAERGDTEVLQQKSSSFTQQRLHDASLDTLRFNHQRQPLKAKPRANVTQMHYARCGIITPEMEYIAIRENMSWQQAKEQGVLDQQHAGEHFGANIPDEITPEFVRSEVACGRAIIPANINHPELEPMIIGRNFLVKINGNIGNSAVTSSIEEEVAKLTWGTRWGADTIMDLSTGKNIHETREWIIRNSSVPIGTVPIYQALEKVDGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHRENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDEAQFGELETLGELTKIAWKHDVQVMIEGPGHVPMHMIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKEGIITYKIAAHAADLAKGHPGAQLRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAAEHGTDITPIAEDEVVRMIDVEAEMRKKSEEFREKGSEIYGKI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Hahella chejuensis (strain KCTC 2396)

Length

638 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.366 kDa

Sequence

MGGTIDINKISKLSESAQVDALSTQPFPASKKIYAEGSRPDIRVAMREITLTPTPLQDGATEENAPLRVYDTSGPYTDPAVEIDVRRGLPRMREAWINDRADTEHLTGATSFYAKSREQNLSLDNLRFEHRHAPRKALAGGNVSQLHYARKGIITPEMEYIAIRENLALEQAEIENAMRSQHPGMNFGANTPRYITPEFVRQEVAAGRAVIPCNINHPEAEPMIIGRNFHVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAEDLNWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLAHHQENFLYTHFEEICEIMKAYDVSFSLGDGLRPGCIADANDEAQFSELRTLGELTEIAWKHDVQTIIEGPGHVPMHMIKENMEEQLKHCKEAPFYTLGPLITDISPGYDHFSSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKQGLIAYKIAAHAADLAKGHPGAQLRDNAMSKARFEFRWEDQFNIALDPDTARAYHDETLPKEGHKLAHFCSMCGPKFCSMKITQDVRDYSAKLEAEKAQAEGASQQEAEQGMQEMSQKYKDAGRRLYHEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Polaromonas naphthalenivorans (strain CJ2)

Length

638 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.723 kDa

Sequence

MAKTNLSVDAADLTSRITRTPFPGSRKIYIEGSRPDIRVPFREVTLTDTLVAEGSETRREANPPLRLFDSSGVYTDPAASIDITRGLSPLRGAWINERQDTEALPGISSAYGRERLNDPALSALRMAHAPVPRRAKAGANVSQMHYARQGIITPEMEYIAIRENLVRAQLAERLATERVPKTGHSFGASIPKDITAEFVRDEVARGRAVIPNNINHPETEPMIIGRNFLIKVNANIGNSAVTSSIEEEVDKLAWSIRWGADTVMDLSTGENIHETREWILRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYVPLTANRLTGIVSRGGSIMAKWCLSHHKESFLYEHFEEICEIMKAYDVCFSLGDGLRPGSIADANDEAQFAELHTLGELTQIAWKHDVQVMIEGPGHVPLQLVKENVEKQLEACFEAPFYTLGPLITDISPGYDHISSAMGAANIGWYGTAMLCYVTPKEHLGLPNRDDVKQGLIAYKIAAHAGDLAKGYPGAQMWDNAVSKARFEFRWEDQFRLAIDPDTAMAYHDETLPKENAKVAHFCSMCGPKFCSMKISQEVREFARLNPSTTTLAKAPGVIPIQQVSSGFEEKAEEFRKGGNEIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Polaromonas sp. (strain JS666 / ATCC BAA-500)

Length

638 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.743 kDa

Sequence

MAKTRLTVDTNDLASRITRAPFPGSAKIYIEGSRPDIRVPFREVTLTDTMVHEGAGEPRREANPPLRLYDASGVYTDPASPIDITRGLPPLRGAWINERADTEALPGISSAYGRERLNDPALAALRMAHAPVPRRAKAGANVSQMHYARKGIITPEMEYIAVRENLVRAQLAERLATERMPKKGHSFNASIPEQITAEFVRDEVARGRAVIPNNINHPESEPMIIGRNFLIKVNANIGNSAVTSSIEEEVDKLVWSIRWGADTVMDLSTGENIHETREWILRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYVPLTANRLTGIVSRGGSIMAKWCLSHHKESFLYERFDEICEIMKAYDVCFSLGDGLRPGSIADANDEAQFAELHTLGELTQIAWKHDVQVMIEGPGHVPLQLVKENVDKQLEACFEAPFYTLGPLITDISPGYDHISSAMGAANIGWYGTAMLCYVTPKEHLGLPNRDDVKQGLIAYKIAAHAGDLAKGYPGAQMWDNAVSKARFEFRWEDQFRLAIDPDTAMAYHDETLPKENAKVAHFCSMCGPKFCSMKISQEVREFARLNPASTTLAAPGVIAIKQIDSGFEEKAKEFREGGSEIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Dechloromonas aromatica (strain RCB)

Length

638 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.951 kDa

Sequence

MNATEQFLAANAHVDEAAVQPLPNSRKIYVEGSRPDIRVPMREVSQDDTPTAFGGEKNPPIYVYDCSGPYSDPAAKIDIRSGLPALRAQWIAERGDVEALADLSSEFGRQRAADPKLDELRFPGLHRKPLRAKAGQNVSQMHYARRGIITPEMEYVAIRENNNRRAYIESLKATGPMGNRMADILGRQHKGQDFGASIPEEITPEFVRSEIARGRAIIPNNINHPESEPMIIGRNFLVKINANIGNSALGSSIQEEVEKMTWSIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICEIMKAYDVAFSLGDGLRPGSIYDANDEAQLGELETLGELTKIAWKHDVQVIIEGPGHVPMHMIKENMDLQLKHCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWDDQFNLGLDPDKAREFHDETLPKESAKVAHFCSMCGPHFCSMKITQEVREFAAQQGLDEAAALEKGMEVKSVEFVKAGAEVYSKI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Aromatoleum aromaticum (strain EbN1)

Length

638 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.811 kDa

Sequence

MNASEKFIAAKAHVDEAAVAPLPNSRKIHVEGSRPDIRVPMREISQADTPASMGAEPNPPIFVYDCSGPYTDPTAKIDIRSGLVALRQQWIEERGDTEVLADLSSEFGRSRAADKALDELRFPGLHRHPRRAKAGMNVSQMHYARRGLITPEMEYVAIRENMNRAAYVESLRTAGPTGEKMAKLLTRQHPGQSFGASIPEEITPEFVRSEVARGRAIIPNNINHPESEPMIIGRNFLVKINANIGNSALGSSISEEVDKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRMTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICDIMKAYDVAFSLGDGLRPGSIYDANDDAQLGELKTLGELTDIAWKHDVQTIIEGPGHVPMHLIKENMDLQLEHCKEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKQDVKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDKAKEFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVRDFAAKEGLKEDEALAKGMEVKAVEFVKSGAEVYRQV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Azoarcus sp. (strain BH72)

Length

638 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.854 kDa

Sequence

MNAKEHFIATEAKVDEAAIAPLPNSRKIYVEGSRPDIRVPMREIRQSDTPASFGAEPNPPIFVYDCSGPYTDPAAKIDIRSGLPALRAGWIAERGDTEQLADLSSEYGRQRAADPRLDELRFPGLHRKPLRARAGANVTQMHYARRGIVTPEMEYIAIRENLRRKDYLESLLAAGPTGQKMAALLTRQHPGQNFGAAIPNEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSALGSSIAEEVDKMTWSIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYIPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICEIMKAYDVAFSLGDGLRPGSIYDANDEAQLGELKTLGELTDIAWKHDVQVMIEGPGHVPLHMIKENMDLQLEQCKEAPFYTLGPLTTDIAPGYDHITSGIGAATIGWYGTAMLCYVTPKEHLGLPNKQDVKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDKAKEFHDETLPKESAKVAHFCSMCGPHFCSMKITQDVRDFAAQQGVDEAEALQKGMEVKAVEFVKSGAEVYRNV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Herminiimonas arsenicoxydans

Length

637 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.308 kDa

Sequence

MNANPKFLSATATVDEAAIQPLPNSTKIYIQGSRPDIRVPMRKITQSDTAASFGFEKNPAIYVYDTSGPYTDPEAKIDIRSGLDTPRLPWILERQDTEELPGPTSEYGIERLNDPKLAELRFNLHRKPRRALAGKNVSQMHYARQGIITPEMEFVAIRENMNRRAYLEELKQSGPKGEKLAELMGRQHPGQSFGAAIPQEITAEFVRSEIARGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKVDVKDGIITYKIAAHAADLAKGHIGAQIRDNALSKARFEFRWDDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVREYAAKQGITEIQALKKGMEVKAIEFVKSGSEIYQKQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bordetella avium (strain 197N)

Length

637 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.112 kDa

Sequence

MNANPKFLAATAEVDAAAVAPLPKSRKIYETGSRPDIRVPFREIEQQDTPTMFGGERNPPLTVYDTSGPYTDPQAHIDIRRGLPELRRAWIEERGDVELLAGPTSDYGRARLQDPQLTAMRFDLRRPPRRAKDGANVTQMHYARRGIVTPEMEYVAIRESLRREHYIESLRASGPEGEKMARRLLRQHPGQSFGAAIPAAITPEFVRDEIARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVSSGIGEEVEKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEALTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTADRMTGIVSRGGSIMAKWCLAHHKESFLYERFEEICEIMKAYDVSFSLGDGLRPGSGYDANDEAQFAELKTLGELTQVAWKHDVQVMIEGPGHVPMQMIKENMELQLEHCHEAPFYTLGPLTTDIAPGYDHITSGIGAALIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAAVRDNALSKARFEFRWDDQFNLGLDPDTAKEFHDETLPKDSMKVAHFCSMCGPHFCSMKITQDVREYAASQGVSAQQALTQGMQEKAIEFVKKGAEVYHRS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)

Length

637 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.996 kDa

Sequence

MNANPKFLAATAEVDAAAVAPLPKSRKVYETGSRPDIRVPFREIEQADTPTMFGGEKNPPLTVYDTSGPYTDPQASIDIRRGLPALRRAWIEERGDTEVLDGPTSDYGKERLTDPKLTAMRFDLQRPPRRARAGANVTQMHYARRGIVTPEMEFIALRENLRREHYLETLRASGPDGEKLAKRLLRQHPGQSFGAALPSAITPEFVREEVARGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSAVSSGIGEEVEKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTADRMTGIVSRGGSIMAKWCLAHHKESFLYERFEEICEIMKAYDVSFSLGDGLRPGSGYDANDEAQFAELKTLGELTQVAWKHDVQVMIEGPGHVPMQMIKENMELQLKHCDEAPFYTLGPLTTDIAPGYDHITSGIGAALIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAAIRDNALSKARFEFRWDDQFNLGLDPDTAKEFHDETLPKDSMKVAHFCSMCGPHFCSMKITQDVRDYAAAQGVSEKDALQQGMQEKAVEFVKKGAEVYHRT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)

Length

637 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.996 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)

Length

637 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.969 kDa

Sequence

MNANPKFLAATAEVDAAAVAPLPKSRKVYETGSRPDIRVPFREISQDDTPTMFGGERNPPLTVYDTSGPYTDPDVRIDIRQGLPALRKAWIEERGDTELLAGPTSEYGKSRLTDPKLTAMRFDLQRPPRRAKAGANVSQMHYARRGIVTPEMEFVAIRENLRREQYLETLRASGPDGEKLARRLQRQHPGQSFGAAIPTIITPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFLVKINANIGNSAVSSGIGEEVEKMTWAIRWGGDTVMDLSTGKHIHETREWIVRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTADRMTGIVSRGGSIMAKWCLAHHKESFLYERFEEICEIMKAYDVSFSLGDGLRPGSGYDANDEAQFAELKTLGELTQVAWKHDVQVMIEGPGHVPMQMIKENMELQLEHCHEAPFYTLGPLTTDIAPGYDHITSGIGAALIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAAIRDNALSKARFEFRWDDQFNLGLDPDTAKEFHDETLPKDSMKVAHFCSMCGPHFCSMKITQDVRDYAASQGVAEQEALQKGMQEKAVEFVKKGAEIYHQT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)

Length

637 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.969 kDa

Sequence

MNANPTFLAATAEVDAAAVAPLPKSRKVYETGSRPDIRVPFREIEQADTPTMFGGEKNPPLTVYDTSGPYTDPQASIDIRRGLPALRRAWIEERGDTEVLDGPTSDYGKERLTDPKLTAMRFDLQRPPRRARAGANVTQMHYARRGIVTPEMEFIALRENLRREHYLETLRASGPDGEKLAKRLLRQHPGQSFGAALPSAITPEFVREEVARGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSAVSSGIGEEVEKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTADRMTGIVSRGGSIMAKWCLAHHKESFLYERFEEICEIMKAYDVSFSLGDGLRPGSGYDANDEAQFAELKTLGELTQVAWKHDVQVMIEGPGHVPMQMIKENMELQLKHCDEAPFYTLGPLTTDIAPGYDHITSGIGAALIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAAIRDNALSKARFEFRWDDQFNLGLDPDTAKEFHDETLPKDSMKVAHFCSMCGPHFCSMKITQDVRDYAAAQGVSEKDALQQGMQEKAVEFVKKGAEVYHRT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Janthinobacterium sp. (strain Marseille)

Length

637 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.278 kDa

Sequence

MNANPKFLSATATVDEASIQPLPNSRKIYIEGSRPDIRVPMREITQSDTAASFGFEKNPPIYVYDTSGPYTDPAAKIDIRSGLDTPRLPWILERNDTEELPGPTSEYGIERLNDPKLAELRFNLHRKPRRALAGKNVSQMHYARQGIITPEMEFVAIRENMNRRAYLEELKKSGPKGEKLAELMGRQHPGQSFGAAIPQEITAEFVRSEIARGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKVDVKDGIITYKIAAHAADLAKGHIGAQIRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAKQGITEIQALKAGMEVKAIEFVKSGSEIYQKQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cellvibrio japonicus (strain Ueda107)

Length

636 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.98 kDa

Sequence

MNTSVDKILSQTAEVDQASVQPFTGSQKIYVQGSRNDIRVPMREISLDDTPTDFGGEKNPPVRVYDTSGPYTDPEVAIDLRAGLPDIRSAWIEERGDTEILSDSQSIFTRERLDDPKLAHLRFNLTRKARRAKPGMNVSQMHYAKKGIITPEMEYIAIRENMALAQVRELGVLNQQHPGMSFGANIPGEITPEFVRSEVARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVEKLTWGARWGADTVMDLSTGKNIHETREWIIRNSHVPIGTVPIYQALEKVNGIAENLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHRENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTEIAWKHDVQTMIEGPGHVPMHMIKENMDKQLEVCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKKDVKEGIITYKIAAHAADLAKGHPGAQLRDNALSKARFEFRWEDQFNLGLDPDTARAYHDETLPKESAKVAHFCSMCGPKFCSMKITQEVRDYAAQQGVNVEGISEDQLVKMIDVEAEMQEKAREFIEQGAELYHKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)

Length

635 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.808 kDa

Sequence

MNATVSSAVQSSLPFSGKTAQVDEGTVKPLPRSQKTYLSGSRPDIRVPMREISQSDTPASMGAEKNPPIYVYDTSGPYTDPAIKIDIRAGLAPLREKWIDERGDTEILSGPASIYGRQRLNDPRLAELRFDLKRSPRRARAGANVTQMHYARGGIVTPEMEFIAIRENQRCEHLADQQREMLARQHPGQDFGAFLPRHITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSALSSSIQEEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYVPMTAKRLTGIVSRGGSIMAKWCLAHHKESFLYTQFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFAELKTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDMQLKYCAEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKDGIITYKIAAHAADLAKGHPGAQLRDNALSKARFEFRWEDQFNLGLDPDKARQFHDETLPQEGAKLAHFCSMCGPHFCSMKITQDVRDFAASKGVSDQEALEKGMEEKASEFVARGTEIYSKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)

Length

633 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.367 kDa

Sequence

MTTPKKTAKISGNEARELSDLSEDIGIRFKYQNSERVYLQGSRDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGAYGDPAAHIDLKQGLPHIRTAWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPEMEFAAIRERMKLDELFRRPEYAKLLKQHTGQSFGANIPTRPDQITPEFVRQEIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQTLEKTGGIAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Neisseria meningitidis serogroup C (strain 053442)

Length

633 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.151 kDa

Sequence

MTTPKKTAKTSGNEARELADLSEDIGIRFKYPNSERVYLQGSRDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGVYGDPAAHIDLKQGLPHIRTAWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPEMEFVAIRERLKLDELSQKPEYAKLLKQHAGQSFGANIPTHPDQITPEFVRREIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTSKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)

Length

633 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.177 kDa

Sequence

MTTPKKTAKTSGNEARELADLSEDIGIRFKYPNSERVYLQGSRDDIRVPLREIRQDDTYTAQGAEANPPIPVYDTSGVYGDPAAHIDLKQGLPHIRTVWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPEMEFVAIRERLKLDELSQKPEYAKLLKQHAGQSFGANIPTHPDQITPEFVRREIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Neisseria meningitidis serogroup B (strain MC58)

Length

633 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.045 kDa

Sequence

MTTPKKTAKTSGNEARELADLSEDIGICFKYPNSERVYLQGSRDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGVYGDPAAHIDLKQGLPHIRTAWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKSGSNVTQLHYARQGIITPEMEFVAIRERLKLDELSQKPEYAKLLEQHAGQSFGANIPTHPDQITPEFVRQEIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)

Length

633 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.056 kDa

Sequence

MTTPKKTAKTSGNEARELADLSEDIGIRFKYPNSERVYLQGSRDDIRVPLREIRQDDTYTAQGAEANPPIPVYDTSGVYGDPAAHIDLKQGLPHIRTAWLNERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKSGGNVTQLHYARRGIITPEMEFVAIRERLKLDELSQKSEYAKLLKQHAGQSFGANIPTHPDQITPEFVRREIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTADRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTSKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)

Length

633 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.599 kDa

Sequence

MNIRSNPDTTLPAVTTGPLPSSRKIYAAPDSAPDLRVPLREIILSEAAGEPNLPVYDTSGPYTDPSVTIDVNAGLPRNRTAWVLERGGVEEYEGRDIKPEDNGNVGADKAAKAFIAHHKPLRGLDGHKITQLEFARAGIITKEMIYVAERENLGRKQQLERAEAALADGESFGAEVPAFITPEFVRSEIARGRAIIPCNINHAELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCNGDPVKLTWELYKDTLIEQCEQGVDYFTIHAGVRLQYIHLTASRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDIMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWTDQFNLGLDPDTAKSFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLNDPTTVGVTISGTIEDGMAQMSAKFKEMGGSVYLDADKVKESNKALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bradyrhizobium sp. (strain ORS 278)

Length

633 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.529 kDa

Sequence

MNIRSNPDTTLPAVTTGPLPSSRKIYAVPDSAPDLRVPLREIILSEAASEPNLPVYDTSGPYTDPSVTIDVNAGLPRNRIAWVLERGGVEEYVGRDIKPEDNGNVGADKAAKAFTAHHKPLRGLDGHKITQLEFARAGIVTKEMIYVAERENLGRKVQLERAEAALADGESFGASVPAFITPEFVRDEIARGRAIIPCNINHAELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCNGDPVALTWELYKDTLIEQCEQGVDYFTIHAGVRLQYIHLTASRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDIMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWTDQFNLGLDPDTAKSFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLNDPATVGMTISGTIEDGMAQMSAKFKEMGGSVYLDAEKVKESNKALS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)

Length

632 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.644 kDa

Sequence

MNAPVNKQMVVDAAAIQPLPNSRKIYVEGSRPDIQVPMREIRQADTPTQFGGEKNPPIFVYDTSGPYSDPAARIDIQSGLAPLRAAWIAQRGDCEQLPGLSSEYGRAREADPKLAELRFNLQRKPRRAKAGRNVTQMHYARRGIVTPEMEFVAIRENLNRRAYVESLQAAGNRRLLDLMTRQHQGQSFGAHLPEEITPEFVREEIAAGRAIIPANINHPESEPMIIGRNFLVKINGNIGNSAVTSSISEEVDKMTWGIRWGADTIMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVNGKAEDLSWEIFRDTLIEQAEQGVDYFTIHAGVRLAYVPMTANRMTGIVSRGGSIMAKWCLAHHRENFLYTHFEDICEIMKAYDVAFSLGDGLRPGSAWDANDEAQLSELKTLGELTEIAWKHDVQVMIEGPGHVPMQLIKENMDKELEWCREAPFYTLGPLTTDIAPGYDHITSAIGAAQIGWYGTAMLCYVTQKEHLGLPNKHDVKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDKARDFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREYAASQGVGEQDALRLGMREKAIEFVKGGGKLYDKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nitrosomonas eutropha (strain DSM 101675 / C91)

Length

632 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.052 kDa

Sequence

MKIPVSRLEKFTSDNARVDTAAIQSLPNSRKIYIQGSRADIRVPMREISQSDTNTSQGIEKNPPICVYDTSGPYSDPDTNIDIRHGLLPLREKWIEEREDTEVLSGLSSSYSLKRLQDPALTAMRFNLTRPVRRAKGGSNVTQMHYARRGIITPEMEFIAIRENQRRERVTDLAKSELLTRQHPGQSFGAAIQEWITPEFVRDEVARGRAIIPANINHPEAEPMIIGRNFLVKINANIGNSALGSSIQDEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFVPMTAKRMTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFAELKTLGELTKIAWKHDIQTMIEGPGHVPMHLIRENMDLQLEHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWNDQFNLSLDPDKARQFHDETLPQEGAKLAHFCSMCGPNFCSMKITQDVRDYAAQQGISENEALQEGMAKKADEFIEKGGEIYRKL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)

Length

632 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

71.042 kDa

Sequence

MKTPVSKLEKFTNDNARVDTAAVQPLPNSRKIYIQGSRADIQVPMREITQSDTATGRGAEKNPPIYVYDTSGPYTDPDTRIDIRHGLPPLREKWIDERGDTEILTGLSSSYSLKRLQDPALTKMRFNLMRPVRHARNGANVTQMHYARRGIITPEMEFIALRENQRRERVADLASNELLNRQHPGQSFGAIIQEWITPEFVRDEVACGRAIIPANINHPETEPMIIGRNFLVKINANIGNSALGSSIQDEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTAKRMTGIVSRGGSIMAKWCLAHHQESFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFAELKTLGELTEIAWKHDVQVMIEGPGHVPMHLIRENMDLQLKYCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWNDQFNLSLDPDKAREFHDETLPQEGAKLAHFCSMCGPNFCSMKITQDVRDYAAQQGISETVALQEGMARKANEFIEKGGELYSKQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

Length

632 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.76 kDa

Sequence

MNIRSNPQQTVPAVTTGPLSSSRKIFASPDAAPDLRVPLREIILSEGAGEPNLPVYDTSGPYTDPSVTIDVNAGLARSRKQWVLERGGVEEYEGRQVKPEDNGNLSTDKAARAFSAYHKPLRGLDGHKITQLEFARAGIITKEMIYVAARENLGRKEQLERAEAALADGESFGAEVPAFITPEFVRSEIARGRAIIPCNINHSELEPMIIGRNFLTKINANIGNSAVTSSVEEEVEKMVWAIRWGADTVMDLSTGRNIHTTREWILRNAPVPIGTVPIYQALEKCNGDPVKLTWELYKDTLIEQCEQGVDYFTIHAGVRLSYIHLTANRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPMHKIKINMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHASDLAKGHPAAQLRDDALSRARFDFRWSDQFNLGLDPDTAKNFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLNDPNSIGMSLSGTAEDGMKQMSAKFKEMGSSVYLDAEKVKESNRVL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5)

Length

632 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.555 kDa

Sequence

MNIRSNPDTTLPAVTTGPLPSSRKIFSTPEAAPDLRVPLREIILTEGAGEPNLPVYDTSGPYTDPAVVIDVNAGLPRTRMAWVKERGGIEEYEGREIKPEDNGNVGASHAAAAFKAHHKPVRGVGDAPITQLEFARAGIITKEMIYVAERENIGRKQQLERAEAALKDGESFGADIPAFITPEFVRSEIARGRAIIPCNINHAELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNAPIPIGTVPIYQALEKCEGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRLPYIHLTANRVTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTQIAWKKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNRNDVKTGVITYKISAHASDLAKGHPAAQLRDDALSRARFDFRWEDQFNLGLDPDTAMAFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLNDPEAVGLPHAGTAEEGMAQMSKKFMDMGGNVYVEADSVKESNKAL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.618 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGSQPDIRIPMREIQLSPTLIGGGKDNPQYEENEAIPVYDTSGPYGDPDVAINVQQGLAKLRQPWIEARADSEELTDRSSAYTKERLADDGLDELRFTGLLTPKRAKAGKCVTQLHYARQGIVTPEMEFIAIRENMGRERIRGDVLRQQHPGVGFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRAKGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella agona (strain SL483)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.75 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIEARADVETLADRSSAYTRERLTDEGLDALRFTGLLTPKRAKAGHRVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMANMSENFRAKGGEIYLKREEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.774 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLISGTKDHPQYEENEAIPVYDTSGPYGDPNIAINIQQGLAKLRQPWIEARADVETLSNRSSAYTRERLTDEGLNALRFTGLLTPKRAKAGHCVTQLHYARNGIVTPEMAFIAIRENMGRERIRSEVLRHQHPGENFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDDAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAWHDETLPHESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMANMSESFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella choleraesuis (strain SC-B67)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.775 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKCVTQLHYARKGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella dublin (strain CT_02021853)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.728 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQGVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella enteritidis PT4 (strain P125109)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.765 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNQQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRITQLHYARQGIVTPEMEFIAIRENMGRERICSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella gallinarum (strain 287/91 / NCTC 13346)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.722 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNQQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRITQLHYARQGIVTPEMEFIAIRENMGRERICSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFPVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSESFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella heidelberg (strain SL476)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.803 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARKGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella newport (strain SL254)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.845 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARKGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEIGMADMSEDFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella paratyphi A (strain ATCC 9150 / SARB42)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.812 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGHRVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSESFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.793 kDa

Sequence

MNQLTNLSPADLSAQHEQDAKDLTRILPASTKVYIQGSRPDIQVPMRQIALTDTPTGLGGEKNPPVMVYDTSGVYTDPEVAIDLNKGLPHVRQAWIEERQDTDVLDTLSSSFGQERLKDIRTADIRFAHIQKPRRAKTGQNVTQMHYAKKGMITPEMEYIAIRENQRQRDEVDMRQHAGQNFGAKNLTEITPEFVRQEVAAGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSALGSSIDEEVSKMTWATRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFKDTLIEQAEQGVDYFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHEENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIQDANDEAQFGELRTLGELTHRAWEHDVQVMIEGPGHVPMHMIKENMDLQLEVCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFNLSLDPDTARSMHDETLPKEAHKSAHFCSMCGPKFCSMKITQNVRNYAQNQETAKDFNPSTEEVEQGLKSMKQAYHDNGQKLYQKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.807 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARRGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ralstonia solanacearum (strain GMI1000)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.091 kDa

Sequence

MPQAKNAPAASFDSLQTELDQKFAYPASSKTYIAGSRPDLRVPMRTIKQTATRTDQGEMLNPPIPVYDTSGPYSDPDVHIDLKAGLAPLRAKWIDERGDTVVLPSLSSEYGQARAHDPATAHLRFAQLTNPRRAKPGANVSQMHYARRGIITPEMEYVALRESLNLQALQDKPEYRKLLKQHPGFSYGANLPQRPEDITPEFVRQEIAAGRAIIPANINHVELEPMAIGRNFRVKINGNLGNSAVTSSLAEEVEKMVWSIRWGADTIMDLSTGKHIHETREWILRNSPVPIGTVPIYQALDKTGGVAEDLTWEMFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTADRITGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADSNDAAQFGELYTLGELTKKAWEHDVQVMIEGPGHVPLQRVQANMDEELKHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVREGIITYKIAAHAADLAKGWPGAQLRDNALSKARFEFRWEDQFNLGLDPEKARAFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYAASLDANATAAEHGMEEKSIEFRKAGAKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O139:H28 (strain E24377A / ETEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.849 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTKELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O127:H6 (strain E2348/69 / EPEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.756 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shigella sonnei (strain Ss046)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.918 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTRTRLADDGLDELRFSGLLTPKRAKTGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAVHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O45:K1 (strain S88 / ExPEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.793 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGHRVTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQRFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli (strain 55989 / EAEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.869 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O157:H7

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.814 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGIADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O157:H7 (strain EC4115 / EHEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.814 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O7:K1 (strain IAI39 / ExPEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.851 kDa

Sequence

MSATKLTRREQRTQAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQFEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGLLTPKRAKTGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSVQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMRISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O81 (strain ED1a)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.764 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGHRVTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLSQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O8 (strain IAI1)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.85 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli (strain K12 / MC4100 / BW2952)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.85 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli (strain K12 / DH10B)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.85 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O9:H4 (strain HS)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.85 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O1:K1 / APEC

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.793 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O6:K15:H31 (strain 536 / UPEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.774 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGHRVTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.798 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITATQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.869 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli (strain K12)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.85 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.782 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQFEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGLLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSVQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli (strain SE11)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.85 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Escherichia coli (strain SMS-3-5 / SECEC)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.745 kDa

Sequence

MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDASGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARRGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSVQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEQCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.8 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella paratyphi C (strain RKS4594)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.803 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKCVTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDISLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella paratyphi A (strain AKU_12601)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.812 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella schwarzengrund (strain CVM19633)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.874 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARNGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAWHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRAKGGEIYLKREEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella typhi

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.802 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICSAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTNIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.845 kDa

Sequence

MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARKGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEIGMADMSEDFRAKGGEIYLKREEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.889 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYLTGTHSGVRVPMREIQLSPTLIGGSKEQPQFEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSMRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGASMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shigella boydii serotype 4 (strain Sb227)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.843 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYLTGTHSGVRVPMREIQLSPTLIGGSKEQPQFEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shigella dysenteriae serotype 1 (strain Sd197)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.806 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLAYDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHSGMSFGARLPENITAESVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARTYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shigella flexneri serotype 5b (strain 8401)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.885 kDa

Sequence

MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARADTEELTVRSSDYTRTRLADDGLDELRFSGLLTPKRAKTGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLHKEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Shigella flexneri

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.885 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Klebsiella pneumoniae (strain 342)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.778 kDa

Sequence

MSTTKLTRREQREHAQRFIDTLAGTAFPNSRRIYVHGSQADIRVPMREIELSPTLVGGDKDNPRYEANEPIPVYDTSGPYGDPDIGIDVRQGLAKLRQPWIDARNDCAPLSERSSAYTKARLADDGLDELRFSGLLTPKRAVAGKCVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRQQHAGEGFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAENLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELRTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKITQEVRDYAAKQNIEAGMADMSHHFRARGGEIYLKQEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)

Length

631 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.785 kDa

Sequence

MSTTKLTRREQREHAQRFIDTLAGTAFPNSRRIYVHGSQADIRVPMREIQLSPTLVGGDKDKPRYETNEPIPVYDTSGPYGDPDISIDVRQGLAKLRQPWIDARNDCAPLSERSSAYTKARLADDGLDELRFSGLLTPKRAVAGKCVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRQQHAGEGFGAHLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAENLTWQVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELRTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEQLEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKITQEVRDYAAKQSIEAGMADMSNNFRARGGEIYLKQEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)

Length

630 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.436 kDa

Sequence

MADIDSRLDTTQATPIGVTTGPIRGSRKIHVASPTGSGIRVAMREILLEPSSGEPPVRVYDTSGPYTDPDATIDIAQGLPELRASWIRARGDVEEVAQREVRPEDNGQLGPDRSGGVPAFPNVRKKVLRAKPGANVSQMHYARRGIITPEMEYVATRENLGRERLAEYVRDGQDWGASIPDYVTPEFVRDEVARGRAIIPSNINHPESEPMAIGRNFLVKINANIGNSAVASDVAAEVDKMVWSIRWGADTVMDLSTGRNIHDTREWILRNSPVPIGTVPIYQALEKVGGIAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPYVPLAAKRVTGIVSRGGSIMAKWCLAHHRESFLYDHFDEITEIMKAYDIAYSLGDGLRPGSIADANDEAQFAELYTLGELTRRAWAQDVQVMIEGPGHVPMHKIKENMDKQLEACGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGTAMLCYVTPKEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPAAQVRDDALSKARFEFRWRDQFNLSLDPDTAEQYHDQTLPAEGAKTAHFCSMCGPKFCSMKISQEVREFAKLQNQDSAGFIAAEEAEKGMAEMSQVYEDTGRELYMGAGGREHD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Hydrogenovibrio crunogenus (strain XCL-2)

Length

630 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.34 kDa

Sequence

MSTFKNALPASNDILTRDPLPASHKTYISGEIHPEIKVPMRAITLTNGETVTVYDTSGPYTDPNIEIDVAQGIPTVRKDWIANRNDVEAYEGRIIDPKDNGYKNRTQMETAIAGASSLMRQPLRAKAGQNVTQLHYARQGIITPEMEFIAIRENQRRDMTRRYLNDPEREARLKGENFGANLLEDITPEFVRKEVAEGRAVIPANINHPESEPMIIGRNFLVKVNANIGNSATTSSIGEEVEKMVWATRWGADTVMDLSTGQNIHTTRDWILRNAPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCIAHHKENFLYTHFEDICEILKQYDVSFSLGDGLRPGSVADANDEAQISELKTLGELTQIAWKHDVQVIIEGPGHVPMHMIKENMDKQLEYCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNRDDVKEGLITYKLAAHAADIAKGHPGARSRDDALSQARFEFRWEDQFNLGLDPEKARAFHDETLPRDSAKVAHFCSMCGPKFCSMKISQEVRDYADKQGLSTEDAVNKGMEEMSQTFKNQGSEVYVNVEDITKTGS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Erythrobacter litoralis (strain HTCC2594)

Length

629 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.371 kDa

Sequence

MADINSPLEIGVTTGPIRGSKKIYVGARTGSGVRVAMREIQLEGGEEPVRVYDTSGPYTDPEVSIDIQAGLPALRREWIMGRGDVEEYAARAVKPEDNGQLGPDRSGGVPAFPNVARTVLRAKPGQNVSQMHYARKGIITPEMEYVAERENVGRAKLETAPDGQAWGAEIPQEITPEFVRDEVARGRAIIPNNINHPETEPMAIGRNFLVKINANIGNSAVASDVAAEVDKMVWSIRWGADTVMDLSTGRNIHDTREWIIRNSPVPIGTVPIYQALEKVGGIAEDLTWDIFRDTLIEQAEQGVDYFTIHAGVRLPYVPMTAKRVTGIVSRGGSIMAKWCLAHHKESFLYERFDEITEIMKAYDIAYSLGDGLRPGSIADANDEAQFAELYTLGELTKRAWEQDVQVMIEGPGHVPMHKIKENMDKQLEACGEAPFYTLGPLVTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPAAKVRDDALSKARFEFRWRDQFNLSLDPDTAEQYHDQTLPAEGAKTAHFCSMCGPKFCSMKITQEVRDFAAKQNSDSYLASENIKRETSAEEAEEAREGMSDMAELYKAKGERLYLPESEAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas fluorescens (strain Pf0-1)

Length

629 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.811 kDa

Sequence

MTTKSKNAINLSDSAKVDEQSVQPFTRSQKVYVQGSRPDIRVPMREITLDVTPTDFGGEINAPVTVYDTSGPYTDPNVVIDVRKGLGDVRSAWIDDRGDTERLPGLSSNFGQERLADPELTKLRFAHVNNPRRAKAGANVSQMHYARKGIITAEMEYVAIRENMKLQEARAAGLLKQQHAGHSFGASIPKEITPEFVREEIARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDEAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIDAVDVDVAQGLAEQAERFKKEGSQLYKKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)

Length

629 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.627 kDa

Sequence

MSTKPKNAAHLSESAQVDSGSVQPFTRSQKIYVQGSRPDIRVPMREVTLDVTPTDFGGEINAPVTVYDTSGPYTDPNVIIDVRKGLADVRSPWIDSRNDTERLPGLSSHFGQQRLSDAELTALRFAHVRNPRRAKAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLLTQQHAGHSFGASIPKEITAEFVREEIARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGAAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDLQTMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIEAVDVDVARGLAEQAERFKQEGSQLYKKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas syringae pv. syringae (strain B728a)

Length

629 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.631 kDa

Sequence

MSIKAKNAAHLRESAQVDSGSVQPFTRSQKIYVQGSRPDIRVPMREITLDVTPTDFGGEINAPVTVYDTSGPYTDPNVIIDVRKGLADVRSPWIDSRNDTERLPGLSSNFGQQRLSDAELTALRFAHVRNPRRAKAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLLTQQHAGHSFGASIPKEITAEFVREEIARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGAAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQTMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIEAVDVDVAKGLAEQAERFKQEGSQLYKKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)

Length

629 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.545 kDa

Sequence

MSTTLKNAAHLSESAQVDSGSVQPFTRSQKIYVQGSRPDIRVPMREITLDVTPTDFGGEINAPVTVYDTSGPYTDPNVIIDVRKGLADVRSPWIDSRNDTERLAGLSSNFGQQRLSDAELTALRFAHVRNPRRANAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLRTQQNAGHSFGASIPKEITAEFVREEIARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGAAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQTMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIEAVDVDVAKGLAEQAERFKQEGSQLYKKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

Length

629 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.825 kDa

Sequence

MTTKLKNASNLSESAQVDQQSVQPFTRSQKVYVQGSRPDIRVPMREITLDVTPTDFGGEINAPVTVYDTSGPYTDPNVVIDVRKGLGDVRSAWIEDRGDTERLAGLSSNFGQQRLADPELTKLRFAHVNNPRRAKAGANVSQMHYARKGIITAEMEYVAIRENMKLQEARAAGLLKQQHAGHSFGASIPKEITPEFVREEIARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDEAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIEAVDVDVAKGLAEQAERFKQEGSQLYKKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas putida (strain W619)

Length

628 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.87 kDa

Sequence

MSKQEKTINLSESAQVDQQSVQPFPRSRKIYVEGSRPDIRVPMREISLHDTPTDFGGEANAPVLVYDTSGPYTDPDVIIDVRKGLADVRSAWIDARGDTERLGGLSSNFGQQRLNDAELAKLRFNHVRNPRRAKAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLLKQQHAGHSFGANIPKEITAEFVREEIARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAANLRIDAVDVSVEEGMREQAERFRQEGSQLYHKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Psychrobacter cryohalolentis (strain K5)

Length

628 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.879 kDa

Sequence

MTISDIGSQATTHTPVKASKADALKTPAHRSETDARFEEDARDLHRILPASRKVYIEGSRPDIQVPMREITLDPTPIQGVSESEWEQNPPFYVYDTSGVYTDPNAAIDLTKGLPKLREGWIDERGDTEQLAGLSSSYGLARARDISTANLRFAHIDKPRRAKAVDGKVGNVTQLHYARRGIITPEMEYIAIRETQKQHELTDMRQHEGETFGAHTPAIITPEFVRSEVAAGRAIIPNNINHPESEPMIIGRNFLVKINANIGNSALGSSIDEEVSKMTWATRWGADNIMDLSTGNHIHETREWLIRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLEYVPLTAGRLTGIVSRGGSIMAQWCMFHNKESFLYTHFEDICEIMKQYDVAFSLGDGLRPGCLQDANDEAQFGELRTLGELTQVAWKHDVQVMIEGPGHVAMNRIKENMDLQLEVCADAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQARDNALSKARFEFRWDDQFNLALDPDTAREFHDETLPKDAHKTAHFCSMCGPKFCSMKITQNVREYAKGLNAQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1)

Length

628 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.812 kDa

Sequence

MNAPDKLATLLSLTREPFPASRKSYLQGSRSDLRVPMREVTLTNGETVSLYDTSGPYTEPGVAIDVRRGLPSVRTPWLDERADTEVYAGRLHQALDDGAKHEDREAERIEQLRLDAAALQRPPRRARAGANVTQMHYARRGIVTPEMEYVALRENGKREWMREYLGDAPREQRLRGNPMGAQIPAIVTPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFLVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGRNIHTTRDWILRNSPVPIGTVPIYQALEKVGGVAEDLTWAIFRDTLIEQAEQGVDYFTIHAGVRLPFIHLTADRRTGIVSRGGSIMAKWCISHHRESFIYEHFEDICDIMKAYDVSFSLGDGLRPGSAADANDEAQFAELRTLGELTQVAWKHDVQTMIEGPGHVPMHMIQANMDEQLKHCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWFGTAMLCYVTPKEHLGLPDREDVKQGIVAYKIAAHAADVAKGHPGARARDDALSKARFEFRWMDQFNLSLDPDTARDFHDETLPKDASKVAHFCSMCGPKFCSMKITQEVRDYAAQRGVSEAQALGAGMAEKSSQFRQAGGEIYIPLAVDKG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6)

Length

628 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.352 kDa

Sequence

MNAPDKLQDLLSLTREPFPASRKVYAEGSEGVRVPMREIALTNGERVTVYDTSGPYTDPLATIDAKLGLPSVRTGWIEARGDTETYAGRNRVALDDGGKHEETARIEALRAQAAALQRTPRRAKAGGNVTQMHYARRGIVTPEMEYVAIRENGKREWMREYLGDAEREARLAGNAKGARIPEIYTPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFGVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGRNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWAIYRDTLIEQAEQGVDYFTIHAGVRLPFIHLTANRRTGIVSRGGSILAKWCITHHKENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSASDANDAAQFAELKTLGELTQVAWKHDVQTMIEGPGHVPMHLIQANMDEQIKHCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADIAKGHPGARARDDAMSKARFEFRWHDQFNLGLDPDTARDYHDETLPKDSSKEAHFCSMCGPKFCSMKITQDVRDYAAAKGLSEEQALADVEQGMAAKSAEFKAQGGELYIPITPVQA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Variovorax paradoxus (strain S110)

Length

628 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.5 kDa

Sequence

MNAPDKFTSLLSLTREPFPASHKCLIPGSRPDLNVPVRDVLLTNGETVSLYDTSGPYTDAKVEIDVRRGLPGVRGAWITERNDTESYEGRSHQALDEGLKHAHDHDAQRLAELRAGASALQRTPRRAKAGANVTQMHYARRGIVTPEMEYVALRENGKREWMAEYLANEERAKRVAGNPMGASIPRIITPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFKVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGKNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGVAEDLTWEIFRDTLIEQAEQGIDYFTIHAGVRLPFIHLTADRMTGIVSRGGSIMAKWCIAHHKESFLYERFEDICDIMKAYDVSFSLGDGLRPGSGADANDEAQFAELRTLGELTQIAWKHDVQTMIEGPGHVPMHMIQANMDEQLKHCHEAPFYTLGPLTIDIAPGYDHISSAIGAAMIGWAGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADVAKGHPGARSRDDALSKARFEFRWQDQFNLGLDPDTAREFHDETLPKDSSKVAHFCSMCGPKFCSMKITQEVREYAAKKGVAEAEAMAEGMAQKSREFMAGGGEIYIPIQPAS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.263 kDa

Sequence

MATRPTDMVNTMQDAAVTCGPIPGSHKRYLGGVRFPELRIPLREIRQSDSRKRDGSLEVNPAIPVYDCSGPYTDPDVVIDIHAGLPAMRWQWSPTDTAIESRPEPGSAYGRARLADVRTADLRFHHRREIRRAANGGNVSQMHYARRGIITPEMEFVAIRENQGLEHLRASHPALFRAHRGESFGAQIPDTITPEFVRDEIARGRAIIPANINHPELEPMIIGRNFLVKINANIGNSAVTSSIAEEVEKMVWSIRWGADTVMDLSTGRHIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYIPLTANRLTGIVSRGGSIMAKWCLAHHQESFLYTHFEEICEIMKAYDVSFSLGDGLRPGSLADANDEAQFAELHTLGELTRIAWKHDVQVMIEGPGHVPMQLIKANMEEELQHCFEAPFYTLGPLTTDIAPGYDHITSAIGAAQIGWYGTAMLCYVTPKEHLGLPDKNDVREGAITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFHLGLDPEKAREYHDETLPQEGAKAAHFCSMCGPHFCSMKISQDLQEYAQSKGEDIETARLEGLQEKAEDFKRLGKNIYLR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acidithiobacillus ferrooxidans (strain ATCC 53993)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.263 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas mendocina (strain ymp)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.55 kDa

Sequence

MSAQQQKNLSESAQVDQQSVQPFPRSQKVYVQGSRPDIRVPMREISLDVTPTDFGGEINAPVTVYDTSGPYTDPNVTIDVRKGLSDVRSAWIEDRGDTEKLPGLSSEFGQRRLNDAELSAMRFAHVRNPRRARAGHNVSQMHYAKKGIITPEMEFVAIRENMKLAEAREAGLLNEQHAGHSFGASIPKEITPEFVRSEVARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGIAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKEQRIDAVDLDAEQGMQAKAAEFKAQGSQLYQKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas stutzeri (strain A1501)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.585 kDa

Sequence

MSVQSNKNLSESAQVDQQSIQPFPRSQKIYVQGSRPDIRVPMREISLDVTPTDFGGEINAPVTVYDTSGPYTDPNVTIDVRKGLADVRSAWIEDRGDTEKLPGLTSEFGQRRLNDAELSAMRFAHVRNPRRAKAEHNVSQMHYAKKGIITPEMEYVAIRENMKLAEAREAGLLVEQHAGQSFGAAIPKEITPEFVRSEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMHMIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAAEHGLTDEQKAIEAGFAEQSSRFKDGGSVIYKQV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas aeruginosa (strain PA7)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.756 kDa

Sequence

MSATQKNNITRLEQLDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDPEVRIDLRKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKPGANVSQMHYAKKGIITPEMEYIAIRENMKLQEARAAGLLDQQHPGHSFGANIPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAAQFGELETLGELTKIAWKHDVQVMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDESKAIEAGFQEQAARFKDEGSVIYKQV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas aeruginosa (strain LESB58)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.784 kDa

Sequence

MSATQKNNITRLEQLDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDPEVRIDLRKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKPGANVSQMHYAKKGIITPEMEYIAIRENMKLQEARAAGLLDQQHPGHSFGANIPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAAQFGELETLGELTKIAWKHDVQVMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDESKAIEAGFQEQAARFKDEGSVIYRQV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas aeruginosa (strain UCBPP-PA14)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.772 kDa

Sequence

MSATQKNNITRLEQLDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDPEVRIDLRKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKPGANVSQMHYAKKGIITPEMEYIAIRENMKLQEARAAGLLDQQHPGHSFGANTPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAAQFGELETLGELTKIAWKHDVQVMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDESKAIEAGFQEQAARFKDEGSVIYRQV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

Length

627 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.784 kDa

Sequence

MSATQKNNITRLEQLDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDPEVRIDLRKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKPGANVSQMHYAKKGIITPEMEYIAIRENMKLQEARAAGLLDQQHPGHSFGANIPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAAQFGELETLGELTKIAWKHDVQVMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDESKAIEAGFQEQAARFKDEGSVIYRQV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.701 kDa

Sequence

MTKQEKAINLSESAQVDQQSVQPFPRSRKVYVEGSRPDIRVPMREISLDDTPTDFGGESNAPVLVYDTSGPYTDPDVIIDVRKGLADVRSAWIEARGDTERLEGLSSDFGQQRLNDAELAKLRFAHVRNPRRAKAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLLNEQHAGHSFGANIPKEITPEFVRQEIARGRAIIPANINHPEVEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAAKIEAVDVTVEQGMREQAERFRQEGSQLYHKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas putida (strain GB-1)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.741 kDa

Sequence

MTKQEKAINLSESAQVDQQSVQPFPRSRKVYVEGSRPDIRVPMREISLDDTPTDFGGETNAPVLVYDTSGPYTDPNVIIDVRKGLADVRSAWIDARGDTERLDGLSSDFGQQRLNDAELAKLRFAHVRNPRRAKAGANVSQMHYARRGIITAEMEYVAIRENMKLQEARAAGLLKEQHAGHSFGANIPKEITPEFVRQEIARGRAIIPANINHPEVEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLIWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAAKIEAVDVTVEEGMREQAERFRQEGSQLYHKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.727 kDa

Sequence

MTKQEKAINLSESAQVDQQSVQPFPRSRKVYVEGSRPDIRVPMREISLDDTPTDFGGESNAPVLVYDTSGPYTDPDVIIDVRKGLPDVRSAWIEARGDTERLEGLSSDFGQQRLNDAELAKLRFAHVRNPRRAKAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLLNEQHAGHSFGANIPKEITPEFVRQEIARGRAIIPANINHPEVEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAAKIEAVDVTVEQGMREQAERFRQEGSQLYHKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudomonas entomophila (strain L48)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.633 kDa

Sequence

MSKQEKAISLSESAQVDQQSVQPLPNSRKVYVEGSRPDIRVPMREISLHDTPTDFGGEKNAPVLVYDTSGPYTDPNVVIDVRKGLGDVRSAWIDARGDTERLEGLSSNFGLQRLNDAELAKLRFAHVRNPRRAKAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLLDQQHAGHSFGASIPKEITPEFVREEIARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAAKIETVDVTVEQGMREQSERFRQEGSQLYQKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.212 kDa

Sequence

MADINSKLEIGVTTGPIRGSRKIHVESARFPGLTVAMREIQLEPSSGEPPVRVYDTSGPYTDPKVTIDIAAGLPTLRRDWIMARGDVEEYDAREVKPEDNGLKGPDRSAGVPPFPNVVKRPLRAKAGQNVSQMHYARRGIITPEMEYVAIRENLGRKQAKEAMIRDGQDWGASIPDYVTPEFVRDEVARGRAIIPSNINHPESEPMAIGRNFLVKINANIGNSAVASDVASEVDKMVWSIRWGADTVMDLSTGRNIHDTREWILRNSPVPIGTVPIYQALEKVGGVAEDLTWEVFRDTLIEQAEQGVDYFTIHAGVRLPYIPLAAKRMTGIVSRGGSIMAKWCLAHHKESFLYENFDEITEIMKAYDVAYSLGDGLRPGSIYDANDEAQFAELYTLGELTKRAWEQDVQVMIEGPGHVPMHKIKENMTKQLEACGEAPFYTLGPLVTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPAAQARDDALSKARFEFRWRDQFNLSLDPETAEQYHDQTLPAEGAKTAHFCSMCGPKFCSMKISQEVRDFAAKQNAGIETFVANEAEAEAGMKAMSDKYDEMGRELYIGAGGREHD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.511 kDa

Sequence

MARTAPAASFESLESDLDQKFAYPASSKTYLTGSRPDIRVPLRTILQTSTRTDKGEMQNPPIPVYDTSGPYSDPDVHIDLKAGLPAVRAKWIEERGDTEVLPGLSSEYGRDRANDPATAHLRFAQLTNPRRAKAGANVSQMHYARKGIITPEMEYVALRESLNLQALYDKPDYKALLRQHPGNALGAGLPLRPEDITPEFVRQEIASGRAIIPANINHTELEPMAIGRNFRVKINGNLGNSAVTSSLAEEVEKMVWSIRWGADTIMDLSTGKHIHETREWILRNSPVPIGTVPIYQALDKTGGIAEDLTWEMFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTADRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADSNDDAQFGELRTLGELTAKAWKHDVQVMIEGPGHVPLQRIQANMDEELKHCYEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWMGTAMLCYVTPKEHLGLPDKEDVREGIITYKIAAHAADLAKGWPGAQLRDNALSKARFEFRWEDQFNLGLDPERARSYHDATLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYAASLPKEAQQGMEEKSIEFLKKGSKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cupriavidus necator (strain JMP 134 / LMG 1197)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.536 kDa

Sequence

MARTAPAASFESLESDLDQKFAYPASSKTYIPGSRPDIRVPMRTILQTSTRTEKGEMPNPPIPVYDTSGPYSDPDVHIDLKAGLPALREKWIAERGDTEVLPGLSSEYGRDRANDPATAHLRFAQLTNPRRAKAGANVSQMHYARKGIITPEMEYVALRESLNLQALYDKPEYKALLRQHPGNALGAGLPLRPEDITPEFVRNEIATGRAIIPANINHTELEPMAIGRNFRVKINGNLGNSAVTSSLAEEVEKMVWSIRWGADTIMDLSTGKHIHETREWILRNSPVPIGTVPIYQALDKTGGIAEDLTWEMFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTADRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADSNDDAQFGELRTLGELTAKAWKHDVQVMIEGPGHVPLQRIQANMDEELKHCYEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWMGTAMLCYVTPKEHLGLPDKEDVREGIITYKIAAHAADLAKGWPGAQLRDNALSKARFEFRWEDQFNLGLDPERARSYHDATLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYAASLPKEAQQGMEEKSIEFLKKGSKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1)

Length

626 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.534 kDa

Sequence

MARTAPAASFESLESDLDQKFAYPASSKTYLTGSRPDIRVPLRTILQTSTRTEKGEMPNPPIPVYDTSGPYSDPDVHIDLKAGLPPVRAKWIEERGDTEVLPGLSSEYGRDRANDPATAHLRFAQLTNPRRAKAGANVSQMHYARKGIITPEMEYVALRESLNLQALYDKPEYKALLRQHPGNALGAGLPLRPEDITPEFVRQEIASGRAIIPANINHTELEPMAIGRNFRVKINGNLGNSAVTSSLAEEVEKMVWSIRWGADTIMDLSTGKHIHETREWILRNSPVPIGTVPIYQALDKTGGIAEDLTWEMFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTADRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADSNDDAQFGELRTLGELTAKAWKHDVQVMIEGPGHVPLQRIQANMDEELKHCYEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWMGTAMLCYVTPKEHLGLPDKEDVREGIITYKIAAHAADLAKGWPGAQLRDNALSKARFEFRWEDQFNLGLDPERARSYHDATLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYAASLPKEAQQGMEEKSIEFLKKGSKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acinetobacter baumannii (strain AB307-0294)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.172 kDa

Sequence

MNQLTNLSSAEISAQHEQDAKDLTRILPASKKVYIEGSRPDIQVPMREISLTDTPTGLGGEHNPPIMVYDTSGVYTDPNVQIDLNKGLPSVRQKWIEERNDTDVLSGLTSKFGQERLKDIRTADIRFAHIQNPRRAKAGKNVTQMHYAKQGIITPEMEYIAIRENQRQREAVDMRQHPGQNFGAKNLKEITPEFVRQEVAEGRAIIPANINHPELEPMIIGRNFLVKINANIGNSALGSSIDEEVAKMTWATRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAENLTWEIFKDTLIEQAEQGVDYFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHEENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIQDANDEAQFSELKTLGELTHRAWEHDVQVMIEGPGHVPMHMIKENMDLQLEVCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFNLSLDPDTARSMHDETLPKEAHKSAHFCSMCGPKFCSMKITQNVRDYANNLTNSDSEVEEGLKAMKEVYQEQGQKLYHKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acinetobacter baumannii (strain AB0057)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.172 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acinetobacter baumannii (strain ACICU)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.172 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acinetobacter baumannii (strain SDF)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.144 kDa

Sequence

MNQLTNLSSAEISAQHEQDAKDLTRILPASKKVYIEGSRPDIQVPMREISLTDTPTGLGGEHNPPIMVYDTSGVYTDPNVQIDLNKGLPSVRQKWIEERNDTDVLSGLTSKFGQERLKDIRTADIRFAHIQNPRRAKAGKNVTQMHYAKQGIITPEMEYIAIRENQRQHEAVDMRQHPGQNFGAKNLKEITPEFVRQEVAEGRAIIPANINHPELEPMIIGRNFLVKINANIGNSALGSSIDEEVAKMTWATRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAENLTWEIFKDTLIEQAEQGVDYFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHEENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIQDANDEAQFSELKTLGELTHRAWERDVQVMIEGPGHVPMHMIKENMDLQLEVCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQARDNALSKARFEFRWDDQFNLSLDPDTARSMHDETLPKEAHKSAHFCSMCGPKFCSMKITQNVRDYANNLTNSDSEVEEGLKAMKEVYQEQGQKLYHKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.172 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acinetobacter baumannii (strain AYE)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.172 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.358 kDa

Sequence

MARTAPAASFESLESDLDQKFAYPASSKTYITGSRPDIRVPLRTILQTATRTEKGEMANPPIPVYDTSGPYSDPDVHIDLKAGLPPVRAKWIEERNDTEVLTGLSSEYGLARANDPATAHLRFAQLTNPRRAKAGANVSQMHYARKGIITPEMEYVALRESLNLQALYDKPEYKALLRQHPGNALGAALPLRPEDMTPEFVRREVAAGRAIIPANINHTELEPMAIGRNFRVKINGNLGNSAVTSSLAEEVEKMVWSIRWGADTIMDLSTGKHIHETREWILRNSPVPIGTVPIYQALDKTGGIAEDLTWEMFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTADRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADSNDDAQFGELRTLGELTAKAWEHDVQVMIEGPGHVPLQRIQANMDEELKHCYEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWMGTAMLCYVTPKEHLGLPDKEDVREGIITYKIAAHAADLAKGWPGAQLRDNALSKARFEFRWEDQFNLGLDPERARSFHDATLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYAASLPEAERGMQEKSIEFVKTGSKIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas campestris pv. campestris (strain B100)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.174 kDa

Sequence

MNAAPTVLLQQTQTLSAAVTQPIPGSRKIFVQGSRADLQVPMREIVLTRTPTLFGGQDNPPLSVYDTSGPYTDPQAAIDLAAGLAPLRADWIAERGDTLPLEALSSSFGRGREHDARLDAVRFPSRRLPRVARSGANVTQMHYARRGIITPEMEFVAIRENQRLEAVTDAVLRKQHPGEAFGAAIQQRITPEFVREEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWSIRWGGDTVMDLSTGKHIHETRDWIIRNSPVPIGTVPIYQALEKVDGRAEELTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTARRVTGIVSRGGSILAKWCLAHHKENFLYTHFEDICEIMKAYDVAFSLGDGLRPGCIADANDAAQFGELETLGELTKLAWKHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYKIAAHAADLAKGHPGVQVRDNALSKARFEFRWDDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYAAEHGISEDHALEAGMQEKSGEFVAQGAQVYRAS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.174 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas oryzae pv. oryzae (strain MAFF 311018)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.227 kDa

Sequence

MNAAPTVLQQQAQSLSEAVTQPIPGSRKIFVQGSRADLQVPMREIALTRTPTLFGGEENPPLSVYDTSGPYTDPQVAIDLAVGLAPLRAHWIAERGDTVALDGLSSSFGRGREHDARLDAVRFPARRLPRVAREGANVTQMHYARRGIITPEMEYVAIRENQRLEAVTDASLRKQHPGEAFGASIQQRITPEFVREEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWSIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGRAEALTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICQIMKAYDVAFSLGDGLRPGCIADANDAAQFGELETLGELTKLAWKHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYAAEHGMDDAQALSTGMQEKSAQFLAQGAQVYRPM

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas oryzae pv. oryzae (strain PXO99A)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.227 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.227 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas axonopodis pv. citri (strain 306)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.229 kDa

Sequence

MNAAPTVLQQQAQSLSEAVTQPIPGSRKIFVRGSRADLQVPMREIALTRTPTLFGGEENPPLSVYDTSGPYTDPRVAIDLAAGLAPLRAQWIAERGDTLALDGLSSSFGRGREHDARLDAVRFPARRLPRVARQGANVTQMHYARRGIITPEMEYVAIRENQRLEAVTDASLRKQHPGQAFGASIQQRITPEFVREEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWSIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGRAEELTWDIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICQIMKAYDVAFSLGDGLRPGCIADANDAAQFGELETLGELTKLAWQHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYANEHGVSEAQALSTGMQEKSAQFVAQGAQVYRAT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas campestris pv. vesicatoria (strain 85-10)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.187 kDa

Sequence

MNAAPTVLQQQAQSLSEAVTQPIPGSRKIFVQGSRADLQVPMREIALTRTPTLFGGEENPPLSVYDTSGPYTDPRVAIDLAAGLAPLRAQWIAERGDTVALDGLSSSFGRGREHDVRLDAVRFPARRLPRVARQGANVTQMHYARRGIITPEMEYVAIRENQRLEAVTDASLRRQHPGQAFGASIQQRITPEFVREEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWSIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGRAEALTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAQRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICQIMKAYDVAFSLGDGLRPGCIADANDAAQFGELETLGELTKLAWKHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFHLGLDPEKAKEFHDQTLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYAAEHGMSEAQALSTGMQEKSAQFVAQGAQVYRAT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xanthomonas campestris pv. campestris (strain 8004)

Length

625 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.174 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118)

Length

624 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.04 kDa

Sequence

MNAPDKFSQLMSLTREPLPASRKIYVPGTQADIQVPMREIMQSNGEAVVVYDTSGPYTDPNANIDVRQGLPSVRSPWIESRGDTESYTGRTPFALDDGLKNGDSESLASLRVQAAGLQRTPRRAKAGANVSQMHYARSGIITPEMEYVAIRENQKLAWMEQYLGNAEREARLAGNSFGANIPKIMTPEFVRDEVARGRAIIPANINHPEVEPMVIGRNFLVKINANIGNSAVTSSIEEEVEKLVWSMRWGADTVMDLSTGRNIHTTRDWILRNSPVPIGTVPIYQALEKVGGVAEDLTWAIFRDTLIEQAEQGVDYFTVHAGVRLAFIHLTANRMTGIVSRGGSIMAKWCIAHHKENFIYSHFDEMTEILKAYDVSYSLGDGLRPGSGADANDEAQFAELRTLGELTQQAWQQDVQVMIEGPGHVPMHMVQANMTEQLKACHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKVGIITYKIAAHVADVAKGHPGVRARDDALSKARFEFRWMDQFNLSLDPDTARNFHDETLPKDSSKVAHFCSMCGPKFCSMKISQEVRDYAKTRGVSEEQALQSGMQTKSEEFRLAGGEMYIPISPA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Myxococcus xanthus (strain DK 1622)

Length

624 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.784 kDa

Sequence

MSGASRSLKVDGKVLEGISRGPLPASRKVYVPGVLHPDLRVPLREISQTPTRLGHGPDAKETANPPVHVYDSSGPYTDPAAELDLRQGLPALRESWILGRNDTEALSGVSSEYGRAREADPRLAGLRFAHRRSPRVAKSGANVTQLHYARKGIITPEMEYVALRENLQVEASLAAQHPGQSWGAAIPRVITPEFVRDEIARGRAIIPANINHPELEPMIIGRNFLVKINANIGNSAVTSSIEEEVEKMVWSIRWGADTVMDLSTGRNIHETREWILRNAPVPIGTVPIYQALEKVGGKAEDLTWELYRDTLIEQCEQGVDYFTIHAGVLLRYVPWTAKRLTGIVSRGGSIMAKWCLAHHRENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTQIAWKHDVQVMIEGPGHVPMHLIQENMTKQLAVCGEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKEGVITYKIAAHAADLAKGHPGAQARDNALSKARFEFRWEDQFNLSLDPERARAFHDETLPAEGAKVAHFCSMCGPQFCSMKITQEVRDFAAKQGVSDDTALQSALDEKSAEFKKAGSQLYR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)

Length

624 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.033 kDa

Sequence

MSAIPEEFLSTQAQVDEQAIQPFPNSRKIHVAGSRPDIRVPMREITLSDTHTSQGREKNPPLTVYDTSGPYTDPEAKIDIRQGLSELRRNWIEERADTEILSDLSSQYGRQRNADSKLDSLRFAHLRPPRRAKAGHNVSQMHYARQGIITPEMEFIAIRENQRLEQYREQLAQHHPGQSFGAHLPSRLTPEFVRSEVARGRAIIPANINHTELEPMIIGRNFLVKINANIGNSAVTSSIAEEVDKMTWAIRWGADTVMDLSTGKNIHETREWIVRNSPVPIGTVPIYQALEKVGGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYVPLTAKRLTGIVSRGGSIMAKWCLAHHTESFLYTHFEEICEIMKAYDVSFSLGDGLRPGSLADANDAAQFAELETLGELTEIAWKHDVQTMIEGPGHVPMHLIKENMDKQLACCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGTAMLCYVTPKEHLGLPNKNDVKEGIITYKIAAHAADLAKGHPSAQIRDNAMSKARFEFRWEDQFNIGLDPDQAREYHDETLPKDSAKVAHFCSMCGPQFCSMKISQDVREYAKQKGLKHHTALEQGMAEKAQEFREKGAEIYHET

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

Length

624 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.719 kDa

Sequence

MSAIPQEILHEAVTAKKASIQPFAASEKVYLQGSRPDLRVPMRKISQSDTPTNTGREKNPPVYVYDTSGPYTDPTVSVDLRLGLPPLREPWIEERGDTELLKGPSSSYGLQRQRDPALASLRFEHIRAPRRAKGGANVTQMHYARQGIITPEMEFVAIRENQKLEALAETYKFQHPGEAFGAAIPQVITPEFVRDEVARGRAIIPSNINHPESEPMIIGRNFLVKINCNLGNSAVSSSIEEEVEKMLWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGIRLPFIPLTAKRTTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICEIMKAYDVAFSLGDGLRPGSIADANDEAQFAELRTLGELTRIAWKHDVQVMIEGPGHVPMHMIKANMEEQLKHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKQDVRDGIIAYKIAAHAADLAKGHPGAQARDNALSKARFEFRWQDQFNLSLDPEKALEFHDETLPQEGAKQAHFCSMCGPHFCSMKITQDVRDYAREHGLDEAQALAKGMEEKSDEFVRSGAEVYQRT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)

Length

623 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.552 kDa

Sequence

MNVHTPRKDEALTVTTGPLPASTKIFTAPEGFPGLKVPFREIALHPSAKEPPVRVYDTSGPYTDPTAQIDLERGLPRTREAWLEARGGTELYEGRDVKPEDNGNVGEKHLARAFPVRNLPRRGLPGHPVTQYEFAKAGIVTAEMAYIAERENMGRKQAAANAAHRIAEGESFGADIPEFITPEFVRDEVAAGRAIIPSNINHPELEPMIIGRNFLVKINANIGNSAVASSVAEEVDKMVWAIRWGADNVMDLSTGRNIHNTREWIIRNSPVPIGTVPIYQALEKVDGIAENLTWEVYRDTLIEQAEQGVDYFTIHAGVRLAYVPLTAKRVTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICDIMRQYDVSFSLGDGLRPGSIADANDEAQFAELETLGELTQIAWAKGCQVMIEGPGHVPMHKIKVNMDKQLKHCGGAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRADVKEGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWEDQFNLALDPERAKEFHDRTLPKEAHKVAHFCSMCGPKFCSMKITQEVRDYAESGMADMASEFRNSGGEIYLEEADAAVKASNRALGGKAAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ruthia magnifica subsp. Calyptogena magnifica

Length

622 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.88 kDa

Sequence

MSQSSKTLKNMSKVNEAFIKPFPSSNKIYVQGSCKDIQVPMREIILTDTIGELAEKNAPIHVYDTSGVYTDPNVKIDLRKGLGSIRSTWIEQRNDTEILTKLSSNFSNERRDDAELDVLRFEHLQVPRRAKNTKNVSQMYYAKQGIITSEMEYIAIRENCKWQEYKDQIGQNEGESFGANIPDVITSEFVRDEVSKGRAVIPANINHPETEPMIIGRNFMVKINGNIGNSALGSSIEQEVDKMVWGIRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQTLEKVNGIAEDLTWEVFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTINRIIGIVSRGGSIMAKWCLAHHTESFIYTHFEDICEIMKQYDVTFSLGDGLRPGCIADANDAAQFGELETLGELTKIAWKHDVQTFIEGPGHVPMQMIKENMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSAIGAAQIGWYGCAMLCYVTPKEHLGLPNQDDVKQGIIAYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARKYHDETMPKQAAKTSHFCSMCGPKFCSMKITQEIKTIDAGEIAKIKAIQIEMDKKSAEFLKNDSEIYMKEGA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata

Length

622 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

69.776 kDa

Sequence

MSRSSIPASRRVSRAKAQAFMDSLTGSSYFPNSRRIYLQGKTPSVHVPMREIKLHPTLIGKNGEHYEDNQPIPVYDTSGPYGDPTIAINVRTGLNRLREIWILARQDSEPISNNNNDRQSSDKQLSFTTNYNPRRASYGRCITQLHYARAGIITPEMEFIALRENMGRERISSNVLHQQHLGSNFGAKKADHITAEFVRQEVAAGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGSYIHETREWILRNSPVPIGTVPIYQALEKVNGVIENLNWDIFYETLLEQANQGVDYFTIHAGVLKRYVLLTASRLTGIVSRGGSIMAQWSLVHNQENFLYEHFSEICKLCAAYDIALSLGDGLRPGSVQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHIPLHMIERNMTDQLKYCHEAPFYTLGPLTTDIAPGYDHFTSGIGAALIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLIAYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARMYHDETIPQTAGKLANFCSMCGPKFCSMKLSKKIRNYTNMKNIKTISNSFMNKLDNSGIKNADR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)

Length

622 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

70.071 kDa

Sequence

MNQSNSTFKNMSNVNEALIKPFPNSNKIYVQGSRKDIQVPMREITLTDTIGELAEKNAPIHVYDTSGVYTDSNVNIDLRKGLGNIRVSWIKERNDTEILTEFSSNFSNERRDDVQLNALRFEHLQVPRRAKDTKNVSQMHYAKQGVITPEMEYIAIRENCKWQEYKDQIGQKKGESFDANIPDLITSEFICSEVAKGRAVIPANINHPEVEPMIIGRNFMVKINGNIGNSVLGSSIEEEVSKMIWGIRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGIVENLNWEIFRDTLIEQAEQGVDYFTIHAGVRLKHVPLTIDRVTGIVSRGGSIMAKWCLAHHTESFIYTHFEDICEIMKQYDVTFSLGDGLRPGCIADANDVAQFGELETLGGLVKIAWKHDVQTFIEGPGHVPMQMIKENMDKQLEECGEAPFYTLGPLTTDIAPGYDHITSAIGAAQIGWYGCAMLCYVTPKEHLGLPNKDDVKQGVIAYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARKYHDETMPKQAAKTSHFCSMCGPKFCSMKITQEIKTMNVDEIAKINSIQIEMDKKSAEFLKNNSEIYMKKNT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

Length

621 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.602 kDa

Sequence

MTAPFLSSLSPTSPLASATAPFPGSRKVYARPADAPHLRVPFREIILSDPGEAPVRVADPSGPYSDPEATIDLRQGLARHRASWASARGNSTVTAGRPAPSEGDFEAFPLTYAPLRRRDETPFTQLEYARAGVITDEMIYVATRENLGRDSAVAGACARLAGGEAFGAALPAHVTPEFVRAEIAAGRAIIPANINHPELEPTIIGRNFLVKVNANIGNSALGSSIEDEVAKLVWAIRWGADTVMDLSTGKAIHATREWILRNSPVPIGTVPLYQALEKVGGDATRLDWAVFEDTLIEQCEQGVDYFTIHAGVRLAHIPLTASRTTGIVSRGGSILAKWCLSHHRENFLYERFADICAILRRYDVAFSLGDGLRPGSVADANDAAQFAELDTLGALTAVAWEHGCQVMVEGPGHVPMHKIKANMDRQLATCGEAPFYTLGPLTTDIAPGHDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRADVKAGVIAYKLAAHAADIAKGHPAAQLRDDAISRARFDFRWSDQFNLGLDPEGARAFHDETLPHAAHKTAHFCSMCGPKFCSMKISHDIRDGALEGADALTQAGLDQMSATFRASGGEVHLDAQALDALAWEGKPAR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)

Length

619 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.301 kDa

Sequence

MHEQRSLTMNALTPAVSTGPLPASRKIHKSGVLHPQIRVPMREISVHPTAGEPPVIVYDPSGPYTDPTVETSIEKGLARLRHEWITARGDVEAYDGRHVRPEDNGFAVGERLTPEFPVRNRPLRARSGKAVTQLAYARAGIITPEMEFVAIRENLGREMLRGTLQRDGEAFGASIPDLVTPEFVRDEVAHGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMDLSTGRNIHNIRDWIVRNAPVPIGTVPLYQALEKVGGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVRLHYIPLTVDRVTGIVSRGGSIMAKWCLHHHRESFLYEHFAEVCDICRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKANMDKQLAVCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKIGVITYKIAAHAADLAKGHPAAKVRDDALSRARFEFRWEDQFNLSLDPETARSFHDQTLPKEAHKLAHFCSMCGPKFCSMRISHDIRAEAQKEGMAAMAAKYREGGDLYVPAEESGAPLMPEAHELS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

Length

619 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.116 kDa

Sequence

MADIPARTEMKVTTGPIRGSRKIHVEGPQGVRVAMREIALEPSSGEPPVRVYDCSGPYTDPNAHIDIMAGLPALRRDWILGRGDVEDYEGRAIKPEDNGLKGPDRSGGVTPFPNVVRRPLRAKAGQNVSQMHYARRGIITPEMEYVAIRENVGRAALKEKLLRDGEDFGAAIPDFVTPEFVRDEVARGRAIIPSNINHPESEPMAIGRNFLVKINANIGNSAVASDVAAEVDKMVWSIRWGADTVMDLSTGRNIHDTREWILRNSPVPIGTVPIYQALEKVGGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTAKRVTGIVSRGGSIMAKWCLAHHRESFLYERFDEICEIMKAYDVAFSLGDGLRPGSIADANDEAQFSELKTLGELTQIAWQHDVQVMIEGPGHVPMHKIKANMDKQLEACGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPAAKLRDDALSRARFEFRWRDQFNLSLDPDTAEQYHDQTLPAEGAKTAHFCSMCGPKFCSMKITQEVRDFAATRNAPADQFIAAGDAEAGMRAMSDVFREKGGEIYLPAAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acidovorax citrulli (strain AAC00-1)

Length

617 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.393 kDa

Sequence

MNAPDKFAQLLALTREPFPASTKNYLIGSRPDVRVPVRDIALTNGEQVSVYDTSGPYTDPAAEIDVRRGLPSVRGAWIEGRGDTERYEGRQRVALDDGSKSEDAARLAQLRAEAAALQRAPLRAKSGASHTGNVTQMHYAKKGIVTPEMEYVALRENGRREWMAQYQQDAAREQRLAGNPMGASIPKIITPEFVRDEVARGRAIIPANINHPEVEPMAIGRTFKVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGKNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWEIFRDTLVEQAEQGVDYFTIHAGVRLAFIHLTAQRRTGIVSRGGSIMAKWCMAHHRESFLYEHFEDICDIMKQYDVSFSLGDGLRPGCASDANDEAQFAELRTLGELTRTAWKHDVQTMIEGPGHVPMHMIQANMTEQLRTCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADVAKGHPGARARDDALSQARFDFRWQDQFNLGLDPETAQQYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREFAAQGMQEKAREFRGTGGELYVPIQPA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acidovorax ebreus (strain TPSY)

Length

614 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.909 kDa

Sequence

MNAPDKFASLLALTREPFPASTKSYLAGSQPGLRVPVRDIQLTNGEVVSVYDTSGPYTDPAVQIDVRKGLASVRGEWIAARGDTEGYEGRVRKALDDGQKAEDGDRLAQLRAEAAALQRQPLRARSGANVTQMHYAKKGIVTPEMEYVALRENGRREWMQQYMQDAAREQRLAGNPLGASIPKIITPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFKVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGKNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYIQLTAARRTGIVSRGGSIMAKWCMAHHKESFLYTHFEDICDIMKAYDVAFSLGDGLRPGCASDANDEAQFAELHTLGELTQIAWKHDVQTMIEGPGHVPMHMIQANMTEQLKTCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADVAKGHPGARARDDALSQARFDFRWQDQFNLGLDPDTAKEYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREFAQQGLQSKAEEFNRTGGELYVPIHRAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acidovorax sp. (strain JS42)

Length

614 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.955 kDa

Sequence

MNAPDKFASLLALTREPFPASTKSYLAGSQPGLRVPVRDIQLTNGEVVSVYDTSGPYTDPAVQIDVRKGLASVRGEWIAARGDTEGYEGRVRKALDDGQKAEDGDRLAQLRAEAAALQRQPLRARSGANVTQMHYAKKGIVTPEMEYVALRENGRREWMQQYMQDTAREQRLAGNPLGASIPKIITPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFKVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGKNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYIQLTAARRTGIVSRGGSIMAKWCMAHHKESFLYTHFEDICDIMKAYDVSFSLGDGLRPGCASDANDEAQFAELHTLGELTQIAWKHDVQTMIEGPGHVPMHMIQANMTEQLKTCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADVAKGHPGARARDDALSQARFDFRWQDQFNLGLDPDTAKEYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREFAQQGLQSKAEEFNRTGGELYVPIHRAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Stenotrophomonas maltophilia (strain R551-3)

Length

614 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.337 kDa

Sequence

MNAQLSALQQQAQQLSESVTRPIPGSRKIHVPGSRPDLQVPMREIALTRTPTLFGGEENAPVTVYDTSGPYTDPEVRIDLSAGLPALRRGWVEERGDTERLEGLSSSFGRDREHDPKLDAVRFPARSLPRRARAGANVTQMHYARRGIITPEMEFVAIRENQRLEAIRDAGLLQQHPGEAFGASIQKIITPEFVRDEIARGRAVLPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVAIGTVPIYQALEKVDGRAEALTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEIMKAYDVTFSLGDGLRPGCIADANDAAQFGELETLGELTKIAWKHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYRIAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVREYAESGMKERSEAFRAAGAEVYHQG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Stenotrophomonas maltophilia (strain K279a)

Length

614 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.226 kDa

Sequence

MNAQLSALQQQAQQLSASVTRPIPGSRKIHVPGSRPDLQVPMREIALTRTPTLFGGEENAPVTVYDTSGPYTDPEVRIDLSAGLPALRRGWVEERGDTEQLEGLSSSFGRDREHDPKLDAVRFPARSLPRRARAGANVTQMHYARRGIITPEMEFVAIRENQRLDAIRDAGLLQQHPGEAFGASIQKVITPEFVRDEIARGRAVLPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVAIGTVPIYQALEKVDGRAEALTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEIMKAYDVTFSLGDGLRPGCIADANDAAQFGELETLGELTKIAWKHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYRIAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYAEAGMKEKSQEFRAGGAEVYRQG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

Length

613 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.463 kDa

Sequence

MSETTLKITTGPLPGSRKIYVEGSRPDVRVAMREIDLTPGSGEAPVRVYDCSGPYTDPSMQVDITKGVPRLREQWILERGDVEHYEGRAHKPEDDGLKPGETIGVPVFDRAGAGLRPLRAKPGKAPTQLAYARAGIITPEMEYVAIRENMKRAEMKAAVVRDGEDFGADIPDEVTPEFVRAEIARGRAVLPANVNHPEAEPMIIGRNFLTKINANIGNSAVASSVDEEVEKMVWATRWGADTVMDLSTGRHIHATREWIIRNSPVPIGTVPIYQALEKVDGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYIPLTAKRTTGIVSRGGSIMAKWCLAHHKENFLYTHFEEICELLKAYDVGFSLGDGLRPGSIADANDAAQFGELETLGELTHKAWAHDCQVIIEGPGHVPMHKIKKNVEKQIELCGEAPFYTLGPLVTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDKQDVREGVVTYKLAAHAADLAKGHPGAQVRDNALSRARFEFRWKDQFNLSLDPEKALAFHDQHLPAEGAKLAHFCSMCGPKFCSMKISQEVRDFAAAEQGMAEMSEKFVNDGAEIYHTEPAQAQQAKPAAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Caulobacter vibrioides (strain ATCC 19089 / CB15)

Length

612 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.968 kDa

Sequence

MNIQSTIKAVAETISTGPIPGSRKVYQAGELFPELRVPFREVAVHPSANEPPVTIYDPSGPYSDPAIQIDIEKGLPRTREALVVARGDVEEVADPRQVKPEDNGFAQGKHLAPEFPDTGRKIYRAKPGKLVTQLEYARAGIITAEMEYVAIRENLRREQDRPCVRDGEDFGASIPDFVTPEFVRQEIARGRAIIPANINHGELEPMAIGRNFLVKINANIGNSAVLSTVADEVDKLVWATRWGADTVMDLSTGRNIHNIRDWIIRNSSVPIGTVPIYQALEKVNGVAEDLNWEVFRDTLIEQCEQGVDYFTIHAGVRLPFIPMTAKRVTGIVSRGGSIMAKWCLAHHKENFLYERFDEICEIMRAYDVSFSLGDGLRPGSTADANDEAQFSELRTLGELTKVAWKHGVQVMIEGPGHVAMHKIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKTGVITYKLAAHAADLAKGHPGAAMWDDAISRARFEFRWEDQFNLGLDPETARKFHDETLPKEAHKTAHFCSMCGPKFCSMKISQEVRDFAAGKAPNSAELGMAEMSEKFREQGSEIYLKTE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Caulobacter vibrioides (strain NA1000 / CB15N)

Length

612 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.968 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

Length

612 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.372 kDa

Sequence

MTIKDARTPASTQNTAQADTAENTDTAEDTEAGKSIGWHKAYVEGSRPDLRVPVRQVHLTNGQSVTLYDTSGPYTDPLVDTDVRRGLAPLRENWIIARGDTEEYAGRPVRPEDDGIKHTSPRGGLRNLDAVFPGRPRQPRRGRDGNAVTQLAYARRGEITPEMEYVAVRENVSPEVVREEIAAGRAVLPANINHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVDKMTWATRWGADTVMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGRAEELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTANRKTGIVSRGGSIMAAWCLAHHKESFLYENFEELCEILAAYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNRIAKRCSVQTMIEGPGHVPMHKIKENIDLQQEICDEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMKISQSITEQFGGTAAAGATAEEVAAGMLQKSKEFAESGNRVYLPLAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Caulobacter sp. (strain K31)

Length

611 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.868 kDa

Sequence

MNVQLPIKDAIGAIPTGERPGSRKVYQAGSLFPDIRVPFREVAVHPSANEPPVTIYDPSGPYTDPHAKIDIEQGLERSREPWIIARGDCELVATPREVKPEDNGFAQGKHLAPQFTAKRPIFKGAQGKLVTQLEYARAGIVTAEMEYVAIRENLRREQDRPCVRDGEDFGASIPDFVTPEFVRQEVARGRAIIPANINHGELEPMAIGRNFLVKINANIGNSAVLSTVADEVDKLVWATRWGADTVMDLSTGRNIHNIRDWIIRNSPVPIGTVPIYQALEKVNGVAEDLNWEVFRDTLIEQAEQGVDYFTIHAGVRLPFIPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYERFEDICEIMRSYDVSFSLGDGLRPGSTADANDEAQFAELRTLGELTKVAWKHGVQVMIEGPGHVAMHKIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKTGVITYKLAAHAADLAKGHPGAAMWDDAISRARFEFRWEDQFNLGLDPETARAFHDETLPKEAHKTAHFCSMCGPKFCSMKISQEVREFAAGMAPNSIEQGMAEMSDKFREQGSEIYLKTE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhizobium meliloti (strain 1021)

Length

611 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.354 kDa

Sequence

MNLVKPLAAAPSVTQGPLPASRKVYKPGDIHPDIRVPMREIALHPTSGEPPVTVYDSSGPYTIENADIRIDAGLPRLRSDWVLKRGDVESYDGRAVKAEDNGFATGERLTPEFPVRNRPLRAKPGKAVTQLAYARAGIVTPEMEFIAIRENLGRKAAKEALARDGESFGASVPDFVTPEFVRQEVAAGRAIIPANINHPEAEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWATRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVNGIAEDLSWEVFRDTLIEQAEQGVDYFTIHAGVRLHYIPLTVDRVTGIVSRGGSIMAKWCLHHHRESFLYEHFEDICDICRAYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKENMDKQLAVCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAARTRDDALSRARFEFRWEDQFNLSLDPETARNFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGLEAMAAKYRDGGDLYMPLDQSNAAPAGE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bartonella bacilliformis (strain ATCC 35685 / NCTC 12138 / KC583)

Length

611 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.453 kDa

Sequence

MQKHTPSVSCSPFPSSHKFYQQSLLFPNVRVPLRKILLTDGSGESPFNVYDTSGPYTDENVIIDITKGLPAIRIPWLSERADTESYPARLVKPEDNGFTHGKDLTPVFEKKRPILRSKNGKSITQMTYARAGIITAEMEYVAIRENEGLIEKNKQHTTSSKAFDASIPEVYTAEFVRNEIACGRAIIPQNINHPECEPMIIGRNFRVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPIYQALEKVHGIAENLTWDIFRDTLIEQAEQGVDYFTIHAGLKLAFIPLTIDRTTGIVSRGGSIIAKWCLHHHKENFLYEHFDEICDIAHTYDVSLSLGDGLRPGSIADANDEAQFAELKTLGELTQIAWEKNVQTMIEGPGHVPMHKIKENMDQQLALCNEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDKNDVKTGVITYKIAAHAADLAKGLPRAQLRDNTLSRARFDFRWHDQFNLSLDPDTARAFHDETMPKEAHKLAHFCSMCGPKFCSMRISHDIRDAVAIKKTRDEGMAAMAEKYQQNGDLYMKVMPSIKETVDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Agrobacterium vitis (strain S4 / ATCC BAA-846)

Length

610 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.13 kDa

Sequence

MNIAPQFPTPEVTTGTLPASAKVHIAGEIHPQIRVPMRQITLHPTSGEPPVNVYDSSGPYTDPNATIAIDAGLPRIRAEWVVARGDVEPYAGRHVKPEDNGFASGEKLTPEFPVRNAPLRAKPGQAVTQLAYARAGIVTPEMEFIAIRENIGRKAAKDALIRDGESFGASIPDYVTPEFVRQEVAMGRAIIPANINHPEAEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMDLSTGRNIHNIRDWIIRNSPVPIGTVPLYQALEKVHGIAENLTWDVFRDTLIEQAEQGVDYFTIHAGVRLSYIHLTVNRVTGIVSRGGSIMAKWCLHHHKESFLYEHFDEICDICRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKENMDKQLKTCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGTAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQVRDDALSRARFEFRWEDQFNLSLDPDTARSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGLEAMAAKYRDGGDLYMPVSDEEKPSVGE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhizobium etli (strain CFN 42 / ATCC 51251)

Length

610 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.12 kDa

Sequence

MNIVAPQLTPVVTTGSLPASTKIVKPGTLYPDLRVPMREISLHPTSGEPPVTVYDSSGPYTDPAHVISIDAGLPRLRESWIKARGDVESYDGRIVKPEDNGFATGERLTPEFPVRNTPLKAKAGRAVTQLAYARAGIVTPEMEFIAIRENLGRQAAKEALARDGESFGAHVPDFVTPEFVRREVAEGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVRLAYIPLTVNRVTGIVSRGGSIMAKWCLHHHKESFLYEHFEEICDICRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKENMDKQLEVCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRSDVKTGVITYKIAAHAADLAKGHPAARIRDDALSRARFEFRWEDQFNLSLDPDTARSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGLEAMAAKYRDGGDLYMPVAEVAKTPAGE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)

Length

610 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.244 kDa

Sequence

MQKNIPSISCSPFPASRKIYQQSPLFSDVQVPLREISLTDGSAEKSLNIYDTSGPYTDNDIIIDITNGLPAISLPWLSKRADTEPYPARPVKPEDNGLLYDKTPPPAFKQKRPILRAKNGKAITQMAYARAGIITAEMEYVAIRENEGLTVKDQPKAQPDKICNGSIPEIYTAEFVRNEIACGRAIIPHNINHPECEPMIIGRNFRVKINANIGNSAVTSSMAEEVDKMVWAIRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVQGIAENLTWDIFRDTLIEQAEQGVDYFTIHAGLRLPFIPLTIDRITGIVSRGGSIMAKWCLHHHKESFLYEHFDEICDIARTYDISLSLGDGLRPGSIADANDEAQFAELKTLGELTKVAWAKDVQVMIEGPGHVPMHKIKENMEQQLDLCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDKNDVKTGVITYKIAAHAADLAKGLPRAQLRDNALSRARFDFRWYDQFNLSLDPETACAFHDETMPKEAHKLVHFCSMCGPKFCSMRISHDIRDTVHRKIKDEGMVAMAEKYQKNGDLYIDVSPPQKKIVNH

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Deinococcus geothermalis (strain DSM 11300)

Length

609 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.341 kDa

Sequence

MSAPTAPQTTLSTAPFPNSEKRYLIGTLYPQVRVPVRAIRQSATLEMIGGLTRQRPNPDVLVPDTSGPYTDPRIHIDLRRGLPHARPWLAADARLEVQAERLSAPLDGAGPLPFPAVPLSRRARSGQAITQMQAARRGEITPEMEFVALRENLRQAEAFELAQQHPGQSFGAAIPREITPEFVRAEVARGRAVIPANVNHPELEPTIIGRNFRVKVNANLGTSIVTSSIEEEVEKMVWATRWGADTVMDLSTGRHIHQTREWILRNSPVPVGTVPIYQALEKVGGVAEELTWEVYRDTLIEQAEQGVDYFTVHAGVRLAHIPLTARRRTGIVSRGGSILAKWCLAHHRENFLYTHFREICEILSAYDITFSLGDGLRPGSIEDANDAAQFAELDTLGELTRVAWEHGVQTMIEGPGHVPMQLIRENMTRQLQVCQEAPFYTLGPLTTDIAPGYDHITSAIGAAQIAWYGTAMLCYVTPKEHLGLPDRQDVRDGVIAYRIAAHAADLAKGHPGAQARDNALSQARFEFRWEDQFNLALDPERARALHDATLPADAAKTAHFCSMCGPHFCSMKLSHDLRADDILNGMAEKAREFRAAGGELYLDRPEGTP

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ruegeria sp. (strain TM1040)

Length

608 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.29 kDa

Sequence

MNTPTRHPTPNVTTGALPASRKIYVAGEMHEGIRVPMREIATHPTAGEAPLPVYDSSGPYTDPDVSTDIREGLAPLRAAWIKARCDVEAYSGRDVTAADNGFVEGDRLVPEFPVKPAPLRGRQRAAPTQLAYARAGIITPEMEFVAIRENQLRDLSPCHCARDGEDFGANIPDYVTPEFVRAEIAAGRAIIPANINHPELEPMIIGRNFKVKINANMGTSSVTSSMEEEVDKLVWAIRWGADTVMDLSTGRNIHNTREWIIRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLIEQAEQGVDYFTIHAGVRLHMVPMTVERVTGIVSRGGSIMAKWCLHHHRESFLYEHFEEICDICRQYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVAMHKIKENMDKQLECCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRDDVKTGVITYKIAAHAADLAKGLPGAQRRDDALSRARFEFRWEDQFNLSLDPETAQSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGFEAMAAKFREGGELYVPLKDTAPEEA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Agrobacterium radiobacter (strain K84 / ATCC BAA-868)

Length

608 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.196 kDa

Sequence

MNIAAKNITPTVTTGPLPASRKIYIPGDIHPDIRVPMREIGLHPTSGEPPVIVYDSSGPYTIEGADIRIEQGLLDLRRNWVLARGDVEAYQGRHVRPEDNGFASGERLTPEFPTLRQPLRAKDGKAVTQLAYARAGIITPEMEFIAIRENLGRKAQAEAMVRDGESFGAHIPDHVTAEFVRQEVAAGRAIIPANINHPEAEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAARWGADTVMDLSTGRNIHNIREWIIRNSPLPIGTVPLYQALEKVEGIAENLTWEVYRDTLIEQAEQGVDYFTIHAGVRLHYIPLTVNRVTGIVSRGGSIMAKWCLHHHRESFLYEHFEEICDICRTYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKENMDKQLAVCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWEDQFNLSLDPETARSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGLEAMAAKYREGGDLYMPVDAVEPSAG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Agrobacterium fabrum (strain C58 / ATCC 33970)

Length

607 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.074 kDa

Sequence

MNIVAKTIPLVVTTGPHAASTKIHKPGILHPHIRVPMREIAVHPTAGEPPVTVYDSSGPYTDPSHPVLIENGLPRLRHDWVVARGDVEAYEGRHVKPEDNGFATGERLTPEFSVRHQPLKATAGKAVTQLAYARAGIITPEMEFIAIRENLGREAAKEKPTRDGESFGAHIPDYVTAEFVRQEVASGRAIIPANINHPELEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVNGIAEDLNWEVFRDTLIEQAEQGVDYFTIHAGVRLHYIPLTVNRVTGIVSRGGSIMAKWCLHHHKESFLYEHFEEICDICRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTQIAWARDCQVMIEGPGHVPMHKIKENMDKQLKTCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHAADLAKGHPAAQVRDDALSRARFEFRWEDQFNLSLDPDTARSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGLEAMAARFKEGGELYMPLPTPASAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

Length

607 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.045 kDa

Sequence

MSIDHSRISTQPFPASEKRYLGGSLFPEVRVPVRAITLSPTVEAFSGVTRTLPNPPLLVPDTSGAYTDPAVATDLQRGLPHARPWLARSERTEETARFSALADMDGPLPYPHVLTPRRARSESRGGQGITQMQAARRGEITPEMEFVALRENLRQQEQAELAHQHPGESFGASLPRLYTPEFVRDEVARGRAVIPANVNHPELEPTIIGRNFRVKINANLGTSIVTSSIEEEVEKMVWATRWGADTVMDLSTGRHIHQTREWIVRNSPVPIGTVPIYQALEKVDGKAEELTWEVYRDTLIEQAEQGVDYFTIHAGVRLAHVPLTARRRTGIVSRGGSILAKWCLAHHQENFLYTRFAEICEIMAAYDVTFSLGDGLRPGSIEDANDAAQFAELGTLGELTRVAWDHGVQTMIEGPGHVPMQLIRENMTRQLDVCQEAPFYTLGPLTTDIAPGYDHITSAIGAAQIAWYGTAMLCYVTPKEHLGLPDKQDVRDGVITYKIAAHAADLAKGHPGAQARDNAISKARFEFRWQDQFNLALDPEKARALHDETLPADAAKTAHFCSMCGPAFCSMKLSHDIRAGDVLAGLEAKAREFRELGGEIYVEGSDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bartonella tribocorum (strain CIP 105476 / IBS 506)

Length

606 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

67.268 kDa

Sequence

MSKNIPLISCSPFPASRKIYQQSPLFSDVRVPLREISLTDGSGEKPLNVYDTSGPYTDKEAIIDLTKGLPAIGSSWLSKRADTEPYPARSVKPEDNGLTSSPIPAFEKKRPILRAKSGKAITQMAYARAGIITAEMEYVAIRENEGLAIKDQQTVQSSPLGGEIPEIYTAEFVRNEIANGRAIIPQNINHPECEPMIIGRNFRVKINANIGNSAVTSSMAEEVDKMVWAIRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVQGIAENLTWDIFRDTLIEQAEQGVDYFTIHAGLRLPFIPMTIDRITGIVSRGGSIMAKWCLHHHKESFLYENFDEICDIASTYDISLSLGDGLRPGSIADANDEAQFAELKTLGELTKTAWEKNVQVMIEGPGHVPMHKIKENMEQQLDLCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDKNDVKTGVITYKIAAHAADLAKGLPRAQLRDNALSRARFDFRWHDQFNLSLDPETACAFHDETMPKDAHKLVHFCSMCGPKFCSMRISHDIRDAAALKKAKGEGMVAMAEKYQERGDIYVEAPQKKRVNS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

Length

606 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.987 kDa

Sequence

MTTADARTPASKQNDGTPDGTTPDAGTPNDGAGKSIGWHKGYVQGSRPDLRVPVRQVHLTNGKHVTLYDTSGPYTDASVDTDVRRGLAPLRENWIIARGDTEEYAGRPVRPEDDGLKHTSPRGGLRNLDAVFPGRPRQPRRSRDGRPVTQLAYARRGEVTPEMEYVAIRENVEAEVVREEIAAGRAVLPANVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVDKMTWATQWGADTVMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGRAEELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTARRKTGIVSRGGSIMAAWCLAHHKESFLYEHFEELCEILATYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNTVAKRFGVQTMIEGPGHVPMHKIKENIDLQQEICEEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMKISQDIRRQHGGSREEIEEGMAEKSKEFAAAGNRVYLPIAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)

Length

604 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.886 kDa

Sequence

MADISDQNIPGHVTTGPIRGSRKIYVEGKNGVRVAMREIDLEPSANEQPVRVYDCSGPYTDPNIKIDIAAGLKPLRREWILARGDVESYEGREIKPEDNGQLGPDRSGGVPPFPNVNHHPLRAKAGANVTQMHYAKKGIVTSEMEYIAIRENCGRAQMKEAMIRDGESFGANIPDFITPEFVRDEIAEGRAVIAANINHPEAEPMIIGRNFLVKINANIGNSAVASDVAAEVEKMVWAIRWGADTVMDLSTGRNIHDTREWILRNSPVPIGTVPIYQALEKVNGIAENLTWEVFRDTLIEQAEQGVDYFTIHAGVRLAYIPLTANRITGIVSRGGSIMAKWCLAHHQENFLYTHFEDICEILKRYDIAFSLGDGLRPGCIADANDRAQFAELETLGELTKIAWKHDVQVMIEGPGHVPMHKIKPNMDKELVACHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPTAHFRDNALSRARFEFRWKDQFNLSLDPDTAESFHDQTLPAEGAKAAHFCSMCGPKFCSMKITQEVREFAAQGMEEMSDQFKEKGGEIYLPAAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Wigglesworthia glossinidia brevipalpis

Length

604 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

68.889 kDa

Sequence

MSSSKKESRNNAKNFIKNFSENLYPNSNRVYLNNSDKSIKVPVRSVELNRTEIIDNNNKIKYEENSPVMIYDTSGPYGDPKSLIDMKSGLNKLRNKWIIDRKDVELISKNLNLENKNNNFKKNIDHYISKKNRCITQLYYAKSGIITKEMEFVSIRENMNYEYSESEAKNNKKITPEFVRKEVASGRAIIPSNINHPESEPMVIGRNFFVKINANIGNSSISSSIEEEVQKLIWSVKWGADTVMDLSTGRNIHETREWILRNSPVPIGTVPIYQALEKANGIVENLNWKIFKKTLLEQAEQGVDYFTIHAGLLLRYIPMTSNRLTGIVSRGGSIIAKWCLFHHKENFIYENFEEICKICSCYDISLSLGDGLRPGSIKDANDEAQFAELYTLGKLTKVAWNYNVQVMIEGPGHVPINMIKENMTKQLKYCHEAPFYTLGPLTTDIAPGYDHFTSGIGAALIGWYGCAMLCYVTPKEHLGLPNKEDVKQGLIAYKIAAHAADIAKGHHISQIRDDAISKARFEFRWEDQFNLSIDPNTARSFHDETLPKSSGKNFHFCSMCGPKFCSMKISQEVRDFAKNKKIIDGMNKMSEIFKKNNNKMSLKK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xylella fastidiosa (strain Temecula1 / ATCC 700964)

Length

603 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.342 kDa

Sequence

MNITTALPLPTHLLSEKVTAPLLGARKIYVTGSRQDIRVPMREIALTPSSARYGGNENLSLVLYDTSGIYTDPQATIDLACGLPRLRTAWIDERADTVEAKLHFKVPESVSVTAPPFPTPPQPLRARDNVAVTQLEYARRGLVTPEMEFVAIREQQRREQTVENLRGQRHAGDAWGALVGTPITPEFVRDEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGTSALSSSIAEEVEKLVWAIRWGADTIMDLSTGRDIHATREWILRNSPVPVGTVPIYQALEKVDGHVDALSWDVFRDTLIEQAEQGVDYVTVHAGVLRDFIPLTASRLTGIVSRGGSIMARWCQAHRSENFLYTHFEELCEIMRAYDVAFSLGDGLRPGCIADANDAAQFAELEILGKLTHIAWNHQVQVMVEGPGHVPMQLIKANMDKQLAACGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNLQDVHDGIIAYKIAAHAADLAKGHPAAQARDDALSKARFEFRWQDQFHLSLDPEKALALHDESLPKEAHKRAAFCSMCGPQFCSMKISQEVRDASSSELSDANTDINTSDGI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Xylella fastidiosa (strain 9a5c)

Length

601 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.06 kDa

Sequence

MNITTALPLPTHLLSEKVTAPLLGARKIYITGSRQDIRVPMREIALTPSSARYGGNENLSLALYDTSGIYTDPQATIDLACGLPRLRAAWIDERADTVEAALYFKVPESVSVTAPPFPTAPRPRRARDNVAVTQLEYARRGLVTPEMEFVAIREQQRREQTVENLRGQRHAGDAWGALVGTPITPEFVRDEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGTSALSSSIAEEVEKLVWAIRWGADTIMDLSTGRDIHATREWILRNSPVPVGTVPIYQALEKVGGHVEALSWAVFRDTLIEQAEQGVDYVTVHAGVLRDFIPLTASRLTGIVSRGGSIMARWCQAHRSENFLYTHFEELCEIMRAYDVAFSLGDGLRPGCIADANDAAQFAELEILGELTHIAWNHQVQVMVEGPGHVPMHLIKANMDKQLAACGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNLQDVHDGIIAYKIAAHAADLAKGHPAAQARDDALSKARFEFRWQDQFHLSLDPEKALALHDESLPKEAHKRAAFCSMCGPQFCSMKISQEVRDASSNELSDGNTNTNDAI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

Length

601 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.486 kDa

Sequence

MTNKDARTPASSQTGEALASPQGDQEAGKSIGWHKAYVAGSRPDLRVPVRQVHLTNGESVTLYDTSGPYTDPSVDTDVRRGLAPLRENWIIARGDTEEYAGRPVRPEDDGIKHTSPRGGLRNLDAVFPGRPRQPRRGRDGQAVTQLAYARRGEITPEMEFVAVRENVSAEVVREEIAAGRAVMPVNVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVEKMTWATRWGADTVMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGRAEELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTANRKTGIVSRGGSIMAAWCLAHHKESFLYENFEELCEILAAYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNRIAKRFNVQTMIEGPGHVPMHKIKENIDLQQEICDEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMKISQDIRREHGGTRTEVEEGMAQKSKEFAAAGNRVYLPLAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)

Length

599 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.203 kDa

Sequence

MSAASANSVTNPSAWENSEIHPKHSYSPIVSGDLEVPETEIQLDDSPTGPNDPVRIYRTRGPECDPTVGLKPLRAQWIDSREDTEEYAGRERNLADDGRSAQRRGAASLEWKGVKPTPRRAKQGKRVTQMHYARQGIITKEMEFVALREHMDPEFVRSEIARGRAIIPNNINHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLRWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTKRITGIVSRGGSIMAGWCLAHHKESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSVADANDAAQFAELKTIGELARRAWEYDVQVMIEGPGHVPLNMVQENNELEQKWAHDAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWHDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFADKIADLGIPQVGGDAEAGMAAKSEEFVAQGSQLYSEVRDNAAHA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Paracoccus denitrificans (strain Pd 1222)

Length

599 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.872 kDa

Sequence

MSQTIPQITTGPLPGSRKIHVPGSLHDIRVPMREIAVSNEPPLVVYDSSGPYTDAAVQADIARGLPDLRGDWQLRRGDVAPYPGRQVTAADNGFAEGARLTPAFPLRRDPLRAAAGRAVTQLAYARAGIVTPEMEFAAIRENEGRLVAHARDGAPMGAELPDLVTPEFVRAEIAAGRAIIPANINHRELEPMIIGRNFKVKINANIGNSAVTSSMEEEVEKMVWAIRWGADTVMDLSTGRNIHNIRDWIIRNAPVPIGTVPLYQALEKVGGVAEDLSWEVFRDTLVEQAEQGVDYFTIHAGVRLHMIPLTARRVTGIVSRGGSIMAKWCLHHHRESFLYERFDEICEIMQAYDVSFSLGDGLRPGSIADANDEAQCAELRTLGELTKIAWARDCQVMIEGPGHVPMHKIKANMEEQLRHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKTGVITYKLAAHAADLAKGHPGAQRRDDALSRARFEFRWQDQFNLGLDPDTAQAMHDETLPKEAHKLAHFCSMCGPKFCSMRISHDIRAEAEKQAGMARMAEKFREGGALYLPVAESVAEAAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Gluconobacter oxydans (strain 621H)

Length

597 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.271 kDa

Sequence

MNASIPAITTGPLPASSKVHVQGTLHDIKVPMRQIEISDECPLNVYDSSGPYTDTAISIDIAKGLADSRGIWLRSRGDVEEYDGRTITAVDNGFAEGERLTPAFPNQRRPLRAVGDRAVTQMAYARAGIITPEMEFVAIRENIGRTQALKEERDGEDFGASIPDFVTPEFVRQEIASGRAIIPANINHRELEPMIIGRNFLVKINANIGNSAVTSSMEEEVEKMVWSIRWGADTVMDLSTGRNIHNIRDWIIRNAPVPIGTVPLYQALEKVGGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLHMIPLTARRVTGIVSRGGSIMAKWCLHHHRESFLYEHFEEICDICRRYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKTNMDKQLEHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKTGVITYKLAAHAADLAKGHPGAQMRDDALSRARFEFRWEDQFNLGLDPDTARAMHDETLPKQAHKVSHFCSMCGPKFCSMKISHDIRAAAEKQDGMEQMAEKFREGGQLYVPVTEPAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)

Length

595 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.849 kDa

Sequence

MSKSTIDLKQLSIQSSFPNSQKRYVTGSRSDIRVPFREISQHPTVTDSGEAENEPILVYDSSGPYTDESYEVNIEKGLPAIRKSWILERGDCEKYEGRDVRPEDNGFTKDDDPRAAREVFPRTSSHKPLRAKKGANVTQMHYAKKGIVTPEMEFVAIRENVSPEFVRDELARGRAILPSNINHPESEPMIIGRNFHVKINANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNSPVPVGTVPIYQALEKVNGVAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPLTAKRVTGIVSRGGSIMAQWCLYHHKENFLYTHFEEICEIMKTYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTKIAWEHDVQVMVEGPGHVPMHQIKENMDKQLDICQEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHPGAQKRDDALSKARFEFRWRDQFNLSLDPERAMEFHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRTYAKEQGLDTEEAIEKGLEEKADEFKQAGGNLYR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)

Length

591 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.286 kDa

Sequence

MKQESVQQKNISIMSSFSGSRKVYVEGSRPDIQVPMREISLSPTTGSFGDEENQPVRVYDTSGPYTDANADVDILKGLKPLRATWIRERGDTEEYEGREIRPEDNGYKGKEKASHSYTGLKRKPLRAKKGQNVTQLHYARKGIITPEMEFIAIREHVSPEFVRDEVASGRAIIPSNINHPESEPMIIGRNFHVKINANIGNSAVTSSIEEEVEKMTWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGVAEDLTWDIYRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGAIMAQWCLAHHEESFLYTHFEEICEIMKTYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMHKIKENVDKQMEICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHPGAQIRDDALSKARFEFRWRDQFNLSLDPERALEYHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRDYAKENNLDEEKAIQKGLEEKAKEFKKAGGSIYS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus subtilis (strain 168)

Length

590 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.932 kDa

Sequence

MQNNSVQQANISIMSSFSGSKKVYVEGSSSDIQVPMREIALSPTTGSFGEEENAPVRVYDTSGPYTDPEVTINIQEGLKPLRQKWITERGDVEEYEGRAIKPEDNGYKKAKPNVSYPGLKRKPLRAKAGQNVTQMHYAKKGIITPEMEFIAIREHVSPEFVRDEVASGRAIIPSNINHPESEPMIIGRNFHVKINANIGNSAVTSSIEEEVEKMTWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGVAEDLTWEIYRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRTTGIVSRGGAIMAQWCLAHHQESFLYTHFEEICEIMKMYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTQIAWKHDVQVMIEGPGHVPMHKIKENVDKQMDICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNRDDVREGVITYKIAAHAADLAKGHPGAQIRDDALSKARFEFRWRDQFNLSLDPERALEYHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRDYAKKNDLSEAEAINKGLKEKAKEFVDTGSNLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42)

Length

590 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.944 kDa

Sequence

MQNQSVQQANISIMSSFSGSKKVYAEGSSPDIRVPMREISLSATTGAFGEEENAPVRVYDTSGPYTDPDVQIDIHEGLGALRTKWITGRGDVEEYNGRIVKPEDNGYKKEDHAAEYPGLQRKPLRAKPGKNVTQLHYARKGIITPEMEFIAIREHVSPEFVREEVASGRAIIPSNVNHPESEPMIIGRNFHVKINANIGNSAVTSSIEEEVEKMTWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGIAEDLTWDIYRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRTTGIVSRGGAIMAQWCLAHHQESFLYTHFEEICEIMKTYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMHKIKENMDKQLEICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNRDDVREGVITYKIAAHAADLAKGHPGAQIRDDALSKARFEFRWRDQFHLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRDYAKENGLTEDEAVNEGLKEKAKEFAEKGSRLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bartonella quintana (strain Toulouse)

Length

588 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.498 kDa

Sequence

MQKKTLSISCNPFPASRKIYQQSLLFSDVRVPLREISLTDGSNEKPLKVYDTSGPYTDKDTIIDFTKGLPAISLPWLSKRADTESYSARSVKPEDNGLAYDTKTVPAFKQKRPILRAKNGKAITQMAYARAGIITAEMEYVAIRENEGLEIKNQQKAQSDETCNGSIPEIYTAEFVRNEIACGRAIIPKNINHPECEPMIIGRNFRVKINANIGNSAVTSSMAEEIDKMVWAIHWGADTVMDLSTGRNIHNIREWILRNSPVPIGTVPLYQALEKVQGIAENLTWDIFRDTLIEQAEQGVDYFTIHAGLRLPFIPLTANRVTGIVSRGGSIMAKWCLHHHTESFLYEHFNEICDIARTYDISLSLGDGLRPGSIADANDEAQFAELKTLGELTKIAWAKDVQVMIEGPGHIPMHKIKENMEQQLDLCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDKNDVKTGVITYKIAAHAADLAKGLPRAQLRDNALSRARFDFRWHDQFNLSLDPETACAFHDETMPKEAHKLVHFCSMCGPKFCSMRISHDIREAAAINKPKGDGIGCQV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Corynebacterium glutamicum (strain R)

Length

587 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

64.765 kDa

Sequence

MTPTQNEIHPKHSYSPIRKDGLEVPETEIRLDDSPSGPNEPFRIYRTRGPETDPKQGLPRLRESWITARGDVATYQGRERLLIDDGRSAMRRGQASAEWKGQKPAPLKALPGKRVTQMAYARAGVITREMEFVALREHVDAEFVRSEVARGRAIIPNNVNHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLQWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAADLTWEVFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTRRVTGIVSRGGSIMAGWCLAHHRESFLYEHFDELCKIFAQYDVAFSLGDGLRPGSLADANDAAQFAELKTIGELTQRAWEYDVQVMVEGPGHVPLNMIQENNELEQKWAADAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWNDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFGDQIAELGMPGVGDSSSAVASSGAQEGMAEKSREFIAGGAEVYRR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)

Length

587 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

64.82 kDa

Sequence

MTPTQNEIHPKHSYSPIRKDGLEVPETEIRLDDSPSGPNEPFRIYRTRGPETNPKQGLPRLRESWITARGDVATYQGRERLLIDDGRSAMRRGQASAEWKGQKPAPLKALPGKRVTQMAYARAGVITREMEFVALREHVDAEFVRSEVARGRAIIPNNVNHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLQWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAADLNWEVFRDTIIEQCEQGVDYMTIHAGVLLAYIPLTTRRVTGIVSRGGSIMAGWCLAHHRESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSLADANDAAQFAELKTIGELTQRAWEYDVQVMVEGPGHVPLNMIQENNELEQKWAADAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWNDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFGDQIAELGMPGVGDSSSAVASSGAREGMAEKSREFIAGGAEVYRR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)

Length

587 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.795 kDa

Sequence

MKEFKVTTGPLPGSEKIYVEGERFPFLRVPMRRIRMSDTILENGEREKNEDVVVYDTSGPYTDTSYEVNLHRGVPKIREQWIEDRGDTLRLEGLSSEYGRMRQSDASLEELRYEHVCTRPRAAKDGCATQLYYARQGIVTPEMEFVAIRENQLIDQVRTRYRAEEGEPLGAVIPRKITPEFVRDEIAAGRAILPANINHPESEPMIIGRNFLVKINANIGNSPISSTIEEEVEKAVWAIRWGADTVMDLSTGDHIHETREWIIRNSPVPIGTVPLYQTLEKVQGDVTKLNWEIFRDTLIEQAEQGVDYFTIHAGLRWHHVPLTLRRLTGIVSRGGSIIANWCTTHKRESFIYEHFEEICRILAHYDVAISLGDGLRPGCIHDANDAAQIAELKTLGELTEIAWKYNVQTIIEGPGHVPMHKIRENMEIQLEACHGAPFYTLGPLVSDVASGYDHITSAIGAAQIGWFGTAMLCYVTQKEHLGLPNREDVREGVVTYKLAAHAADLAKGHPTAYWRDYMMSKARFEFRWKDQFHLSLDPEKAIQFHDATLPDEGHKEAHFCSMCGEHFCSMRANKNFRKLLNEEAVSK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Porphyromonas gingivalis (strain ATCC BAA-308 / W83)

Length

587 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

66.781 kDa

Sequence

MKEFKVTTGPLPGSEKIYVEGERFPFLRVPMRRIRMSDTILENGEREKNEDVVVYDTSGPYTDTSYEVNLHRGVPKIREQWIEDRGDTVRLEGLSSEYGRIRQSDASLEKLRYEHVCTRPRAAKDGCATQLYYARQGIVTPEMEFVAIRENQLIDQVRTRYRAEEGEPLGAVIPRKITPEFVRDEIAAGRAILPANINHPESEPMIIGRNFLVKINANIGNSPISSTIEEEVEKAVWAIRWGADTVMDLSTGDHIHETREWIIRNSPVPIGTVPLYQTLEKVQGDVTKLNWEIFRDTLIEQAEQGVDYFTIHAGLRWHHVPLTLRRLTGIVSRGGSIIANWCTTHKRESFIYEHFEEICQILARYDVAISLGDGLRPGCIHDANDAAQIAELKTLGELTEIAWKYNVQTIIEGPGHVPMHKIRENMEIQLEACHGAPFYTLGPLVSDVASGYDHITSAIGAAQIGWFGTAMLCYVTQKEHLGLPNREDVREGVVTYRLAAHAADLAKGHPTAYWRDYMMSKARFEFRWKDQFHLSLDPEKAIQFHDATLPDEGHKEAHFCSMCGEHFCSMRANKNFRKLLNEEAVSK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus weihenstephanensis (strain KBAB4)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.796 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGTREGMKVPMREIEQSDTNGVQNPPIRVYDTSGPYTDPEYKVELEKGLQAPRHSWTLGRGDVEAYEGREIKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVSQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRMTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAVEFKETGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus anthracis

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.798 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIIKSEMEYVAIREGVDPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain AH820)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.771 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVDPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain ATCC 10987 / NRS 248)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.844 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPEYKVELEKGLQAPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain G9842)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.674 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSETNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWIMGRGDVDAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVRTGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAEEFKEAGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain 03BB102)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.771 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain B4264)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.746 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSETNGVPNPPIRVYDTSGPYTDPEYKVELEKGIPTPRHSWIMGRGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRQPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVRTGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAEEFKEAGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain AH187)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.771 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKDTGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.872 kDa

Sequence

MEQSVSAEQIELKSSLPGSKKVYVEGSREGMKVPMREIELSDTNGVPNSPIRVYDTSGPYTDPEYKVELEKGIPTPRRNWIIERGDVEEYEGREIKPEDDGVKAASNHTPVFPQMDRKPLRAKKGANVTQMHYARKGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVQGIAENLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPLTAKRMTGIVSRGGSIMAQWCLYHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFAELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKEIDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAQQRDDALSKARFEFRWRDQFNLSLDPERAMEFHDETLPAEGAKTAHFCSMCGPKFCSMKISHDIREYAKENNLETTEAIEKGMKEKAKEFKEAGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain Q1)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.771 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKDTGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.728 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSETNGVPNPPIRVYDTSGPYTDPEYKVELEKGIPTPRHSWILGRGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVRTGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAEEFKEAGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus cereus (strain ZK / E33L)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.771 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus thuringiensis subsp. konkukian (strain 97-27)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.771 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus anthracis (strain A0248)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.798 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus anthracis (strain CDC 684 / NRRL 3495)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.798 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus thuringiensis (strain Al Hakam)

Length

586 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.787 kDa

Sequence

MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVDPEFVRKEIAEGRAILPANINHPEAELMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacillus pumilus (strain SAFR-032)

Length

585 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

65.693 kDa

Sequence

MKEKKNIPTTQSLLSSFDGSRKVYEKGSRPDILVPKREIALTQTVTQAGMIQNEPIRVYDTSGPYTDEHAHIDVTKGLNRLRAAWVEERGDTESYEGRHVKPEDNGYRSRNGSHQHIHTDFHHKPLRAKQGACVTQMHYAKKGIVTPEMEFIALREGLSPEFVREEVASGRAVIPANINHPESEPMIIGRNFHVKINANIGNSAVTSSIDEEVEKMTWAIRWGTDTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGVAEDLTWDVYRDTLIEQAEQGVDYFTIHAGVRLRYIPLTVDRVTGIVSRGGAIMARWCLAHHQENFLYTHFEDICEIMKTYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMDKIKENVDKQMEICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKEDVREGVIAYKIAAHAADLAKGHPAAQKRDDALSKARFEFRWRDQFNLSLDPERAMAFHDETLPAEGAKTAHFCSMCGPKFCSMKISHDIRNQSEEVKKEMEKKAKEFISGGSQIYSS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)

Length

580 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

64.128 kDa

Sequence

MTPTQNEIHPKHSYSPIRKHGLEVPETEIALDDSPSGPNEPFRIYRTRGPETDPTLGLPRLRTPWITARGDVTEYTGRERLLIDDGRSAMRRGQASAEWKGQKPAPLKALPGKRVTQMAYARAGEITREMEFVALREHVDPEFVRSEVARGRAIIPNNVNHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLQWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAADLSWEVFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTRRVTGIVSRGGSIMAGWCLAHHRESFLFEHFDELCEIFAQYDVAFSLGDGLRPGSLADANDAAQFAELKTIGELTQRAWEYDVQVMVEGPGHVPLNMIQENNELEQKWAADAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRNDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWNDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFGEQIAELGMPGVGASDSTEGMKEKSREFVAGGGEVYRE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Geobacillus sp. (strain WCH70)

Length

573 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

64.393 kDa

Sequence

MQNIKSFMQFPASKKVYVEGSRPDIRVPMREITLSPTKTETGIIENEPVRVYDTSGPYTDPDFQPDIQKGLPPLRKRWILERGDVEEYEGRPVKPEDNGFRNGKQSEITLPFERKPLRAKKGKTVTQMHYAKRGIITPEMEFVAIRENIDPEIVRQEVAAGRAIIPSNINHPESEPMIIGSRFHVKINANIGNSAVTSSIEEEVEKMLWAVRWGADTIMDLSTGKHIHATREYIIRNSPVPVGTVPIYQALEKVNGVVEDLTWEIYRDTLIEQAEQGVDYFTIHAGVLLRYIPMTVNRTTGIVSRGGSIMAQWCLAHHEENFLYTHFEEICEILKTYDIAVSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMHKIKENVDKQIEICKGAPFYTLGPLTTDIAPGYDHITSAIGAAIIGAYGTAMLCYVTPKEHLGLPNKDDVREGVIAYKIAAHAADLAKGHPGAQRRDDALSKARFEFRWNDQFNLSLDPDRAREYHDETLPAEGAKVAHFCSMCGPKFCSMKISHELQKTVREEGMKQKAKEFVENGSSLYR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chlorobium phaeovibrioides (strain DSM 265 / 1930)

Length

571 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.74 kDa

Sequence

MSTNTTHTSCPKESREDRAFQKTYAEGTLWPVKVGMQTLNLSGTYSCNGVPFSSLPLYDTSGPHSDPSLQVNPAEGLAPVRDSWNFIKSISVPCAAPVNTESMTERHPRMAEDGIALTQMHFARKGVITPEMEYVAIRENQQLEEWIRANGRGGTPSEPITAEFVMSEVAAGRAIIPANINHPELEPMIIGRNFRVKINANIGNSALSSSIAEEVEKAVWACRWGADTVMDLSTGANIHKTREWILRNSPVPIGTVPIYQALEKVNGVAENLTWELYRDTLLEQAEQGVDYFTIHAGILEKHLPLADKRRTGIVSRGGSIMAKWCRANKQENFLYTHFEEICAILKCYDIAVSLGDALRPGSISDANDEAQFGELKVLGELTTLAWKHEVQVMIEGPGHVPLNMIEENMQKQLEYCHEAPFYTLGPLVTDIAAGYDHVNSAIGGTLIASYGCSMLCYVTPKEHLGLPDRNDVREGVVVHKIAAHAADLAKGSPIARLRDELMSSARFAFNWEDQFNLSLDPPKTREVHAASMKAAGHEGEKADFCTMCGPDFCSMKKSKEASAASAIEPGR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)

Length

568 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

63.394 kDa

Sequence

MSTAPSNNRLNRQQAESFLSSLSGHYYPNSSREFISGSNKDIQVPFRRIHLSETLHQPTPGVKLPPNEPVDVYDTSSVYGDPDATIDVKAGLKKVRENWIQERHSENQQYNHGITQLAYARRGVITPEMEFIALRENMGRGHLKNPITPEFVRDEVASGRAIIPVNTHHPESEPMIIGRNFLVKVNANIGNSSVSSSIEEEVEKLVWATRWGADTVMDLSTGRNIHQTREWILRNSPVPIGTVPIYQALERVNGVAEDLSWPVFKDVLLEQAEQGVDYFTIHAGVLHDFIKLTAKRVTGIVSRGGSIMAKWCMAHQQESFLYQHFRDICKICAKYDVSLSLGDGLRPGSIADANDEAQFAELRVLGELTQIAWEYDVQVMIEGPGHVPMHKIQENMDEQLKHCHGAPFYTLGPLTTDIAPGYDHITSCIGAAMIGAFGCAMLCYVTPKEHLGLPNKEDVKQGMIAYKIAAHAADLAKGHPGAQARDDAMSKARFEFRWEDQFNLALDPVTARSYHDETLPQDSNKTAQFCSMCGPKFCSMKISHEVRQYNPDTRIDVKVKDAATEGAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chlorobium luteolum (strain DSM 273 / 2530)

Length

565 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.609 kDa

Sequence

MAHSNQDPHCPEHRLYGNSSRKIHVDGTLWPLRVGMREITLSRPYLSGGQEFTSFPIYDTSGPYSDPSVTFDPEKGIPPVRDGWGFIARESDRAAATAPEGSMTTRIPRKAKEGSGITQMHFAKKGVITPEMEYVAIRENQRLEEWTLSHGRGAVHATPVTPEFVRSEIARGRAIIPANINHPELEPMIIGRNFRVKINANIGNSALSSSIAEEVEKSVWACRWGADTVMDLSTGKNIHTTREWILRNSPVPIGTVPIYQALEKVGGIAEALTWELYRDTLIEQALQGVDYFTIHAGILRRHLPPAEKRLTGIVSRGGSIMAKWCKANGKENFLYEHFEEICEILETYDIAVSLGDALRPGSISDANDEAQFGELKVLGELTTAAWQHDVQVMIEGPGHVPFHMIEENMQKQLEYCHEAPFYTLGPLVTDIAAGYDHVNSSIGGTLIAFHGCSMLCYVTPKEHLGLPDRDDVREGVVVHRIAAHAADIAKGSPAAWLHDELMSQARYAFAWEDQFNLSLDPEKARKLHTESLKAAGHTGADPDFCTMCGPDFCSMKKSKEAKTLH

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Length

565 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

63.833 kDa

Sequence

MEQKIKFPRSQKVYLPGKLYPNIRVAMRKVEQVPSVSFEGEEKIATPNPEVYVYDTSGPFSDPSMSIDLKKGLPRLREEWIVGRGDVEQLPEITSEYGQMRRDDKSLDHLRFEHIALPYRAKKGEAITQMAYAKRGIITPEMEYVAIRENMNCEELGIETHITPEFVRKEIAEGHAVLPANINHPEAEPMIIGRNFLVKINTNIGNSATTSSIDEEVEKALWSCKWGGDTLMDLSTGENIHETREWIIRNCPVPVGTVPIYQALEKVNGVVEDLNWEIYRDTLIEQCEQGVDYFTIHAGIRRHNVHLADKRLCGIVSRGGSIMSKWCLVHDQESFLYEHFDDICDILAQYDVAVSLGDGLRPGSIHDANDEAQFAELDTMGELVLRAWEKNVQAFIEGPGHVPMHKIKENMERQIEKCHDAPFYTLGPLVTDIAPGYDHITSAIGAAQIGWLGTAMLCYVTPKEHLALPDKEDVRVGVITYKIAAHAADLAKGHPGAQVRDNALSKARYEFRWKDQFDLSLDPERAQGYFRAGHHIDGEYCTMCGPNFCAMRLSRDLKKNAKSDK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ehrlichia canis (strain Jake)

Length

565 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

63.663 kDa

Sequence

MILYNIFLVKMKVDFINTVFPSSTKEYIPGTIYNNIKVGMRKIHFNDNTESILVYDTGGLHTDQNVEVDINHGITKLRLNWIIDRQDVEYYERQPVLNSEHIFTSQSNKVLRANSTKPVTQIFYARNNIITPEMEYIAIRENSLRQKILSYKPTVMSPEITPEFVRQEVASGRAIIPANINHPESEPMIIGKNFLVKINANIGNSVVSSNIEEEVQKMIHAITYGADTVMDLSTGNNIHDIREWIIRNSPVPIGTVPIYQALNKVNGVVGDLNFNVFKETLIEQAEQGVDYFTIHAGVLKNYISHTDNRLTGIVSRGGAIMAHWCTIHNKENFLYTNFEEICDIMKRYDIAFSLGDGLRPGSIADANDTAQFLELKTLGELTDIAWQHDCQAMIEGPGHVPMHLIKENMEKQIHFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAITGWYGTSMLCYVTPKEHLGLPNIQDVKDGVIAYKIAAHAADLAKGNPSAYIRDYALSYARFNFKWHDQFNLSLDPETARSLHDESLPSEHAKSAHFCSMCGPKFCSMKLTHHLKEHSTG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)

Length

564 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

64.065 kDa

Sequence

MEQRIKFPRSEKVYLSGKLFPEIRVGMRKVEQVPSTTFEGEKKVITPNPHVYIYDTSGPFSDPDIEIDLKKGLPRLREEWILNRGDVEQLPEISSEYGRMRRDDGSLDHLRFEHIALPYRAKAGRHITQMAYAKQGIVTPEMEYVAIRENMNCEELGIETHITPEFVRQEIAEGRAVLPANINHPEAEPMIIGRNFLVKINTNIGNSATTSSIDEEVEKAMWSCKWGGDTLMDLSTGENIHETREWIIRNCPVPVGTVPIYQALEKVNGKVEDLTWELYRDTLIEQCEQGVDYFTIHAGIRRHNVHLAEKRLCGIVSRGGSIMSKWCLVHDRESFLYEHFDDICDILAQYDVAVSLGDGLRPGSTHDANDEAQFAELDTMGELVVRAWEKNVQAFIEGPGHVPMHKIRENMERQIEKCHNAPFYTLGPLVTDIAPGYDHITSAIGAAQIGWLGTAMLCYVTPKEHLALPDKEDVRVGVITYKIAAHAADLAKGHPGAQVRDNALSKARYEFRWKDQFDLSLDPERAFSYFHAGRHTDGEYCTMCGPNFCAMRLSRDLKKTQKQK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Bacteroides fragilis (strain YCH46)

Length

564 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

64.065 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chlorobium phaeobacteroides (strain BS1)

Length

563 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.635 kDa

Sequence

MSTSPDNLFCPEQNFYGPDSEKIYIDGSLHPVKVGMRRIKLSKTYTLHGTDFSSFPLYDTSGPYSDPSVTIDLHKGLPSTRDFWQKNRTDIEVCPGKNPSPMNNRTPVRAKQGKSVTQMHYARKGIITPEMEYVAIRENQQLEEWIERFSSNGSSVKPVTPEFVRDEIAKGRAIIPANINHPELEPMAIGRNFRVKINANIGNSALASSISEEVEKSVWACRWGADTVMDLSTGKNIHQTREWILRNSPVPIGTVPIYQALEKVGGKAEELNWNIYRDTLIEQAEQGVDYFTIHSGILLDFLPAAQRRTTGIVSRGGSIIAKWCRAHKQENFLYSHFDDICDILRSYDIAISIGDALRPGSIADANDEAQFSELKTLGELTLKAWKYDVQVMIEGPGHVPLNLVEENMRKQLEYCHEAPFYTLGPLVTDIAAGYDHVNSAIGGTLLASLGCAMLCYVTPKEHLGLPDKNDVREGVIVHKLAAHAADIAKGSPSALLHDKLMSSARYSFAWNDQFNLSLDPVKTRQVHAESSQQNTGDGTDDHFCTMCGPDFCSMKKSQEVTGK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Geobacillus thermodenitrificans (strain NG80-2)

Length

563 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

63.051 kDa

Sequence

MENIRSFMSFPASRKVYVEGSRPDVRVPMREIALSPTKTPQGEVENKPVRVYDTTGPYTDPDFEPNVEKGLPLLRRNWIVERGDVEETEPQSTAGRAASLPFARRPLRAKPGKVVTQMHYAKKGIITPEMEFVAIREQIDPEIVRQEVAAGRAIIPSNINHPESEPMIIGRRFHVKINANIGNSAVSSSIENEVEKLLWAVRWGADTVMDLSTGKQIHETREYIIRNSPVPIGTVPIYQALEKVGGVPEKLTWDVYRETLIEQAEQGVDYMTIHAGVRLHYIPLTVNRTTGIVSRGGSIIAQWCLAHHEENFLYTHFEEICEILKQYDVAISLGDGLRPGSIADANDEAQFAELETLGELTKIAWEHDVQVMIEGPGHIPMQKIRENVEREQELCHGAPFYTLGPLVTDIAPGYDHITSAIGAAIIGAYGTSMLCYVTPKEHLGLPNKEDVRVGVVTYKIAAHAADLAKGHPAAQQRDDALSKARFEFRWNDQFNLSLDPERAREYHDETLPAEAAKTAHFCSMCGPKFCSMNISHELQRKIKEEGMKEKANEFVRGGSSLYR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Geobacillus kaustophilus (strain HTA426)

Length

562 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

63.253 kDa

Sequence

MENIRSFMSFPESRKVYIEGSRPDVRVPMREIALSPTKTPQGMVENKPVRVYDTTGPYTDPDFEPDVEKGLPPLRRRWIVERGDVEEMERSSVAIQRSLPFVRRPLRAKPGKTVTQMHYAKRGIITPEMEFVAIREQIDPEIVRQEVAAGRAIIPANINHPESEPMIIGRRFHVKINANIGNSAVSSSIEDEVEKLLWAVRWGADTVMDLSTGKHIHETREYIIRNSPVPVGTVPIYQALEKVGGVPEKLTWDVYRETLIEQAEQGVDYMTIHAGVRLHYIPLTANRTTGIVSRGGSIIAQWCLAHHEENFLYTHFEEICEILKQYDVAISLGDGLRPGSIADANDEAQFAELKTLGELTKIAWKHDVQVMIEGPGHIPMHKIRENVEREQEICHGAPFYTLGPLVTDIAPGYDHITSAIGAAIIGAYGTAMLCYVTPKEHLGLPNKEDVRAGVVAYKIAAHAADLAKGHPAAQQRDDALSKARFEFRWNDQFNLSLDPERAREYHDETLPAEAAKTAHFCSMCGPKFCSMNISHELQRKIKEEGMKEKAQQFIRQGSSLYQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prosthecochloris aestuarii (strain DSM 271 / SK 413)

Length

562 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.598 kDa

Sequence

MTTSSDNLFCPEQNFYGPASKKIYVDGSLYPLKVGMRKITLSKTYTLQESSFSELPMYDTSGPYSDPSAKIDLQKGLPCIRDTWQTQQKETRPSNQSSHKPLNGRTPIRAAEGGSVTQMHLARKGIVTPEMEYVAIRENQMLEEWIERFSIGGNTFSPVTAEFVRDEVARGRAIIPANINHPELEPMVIGKNFRVKINANIGNSALGSSIQEEVEKAVWACRWGADTVMDLSTGSNIHQTREWILRNAPVPIGTVPIYQALEKVGGVAEELTWEIYRDTLLEQAEQGVDYFTIHSGILKDFLPVAARRMTGIVSRGGSIIAKWCRAHKRENFLYTHFDEICEILRAYDIAISIGDALRPGSIADANDEAQFAELKTLGDLTLKAWEYDVQVMIEGPGHVPLNLVAENMTRQLEYCHEAPFYTLGPLVTDIGAGYDHINSAIGGTLLASLGCAMLCYVTPKEHLGLPGKEDVREGVIVHKLAAHAADLAKGNPTAWLHDNIMSTARYSFAWEDQFNLSLDPVKARKWRKESSPEQGENIEEERFCTMCGPDFCSMKKSQEATE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)

Length

560 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

61.94 kDa

Sequence

MNTFSDNIFCPEHRMYGNASKKTHTKGCIHPIEVGMRTLSLTKTYTCRGIEFSSIPLYDTSGPYSDPSVIINPEKGLNPLRDKWKFNSENTEPVSEQGNETAAARVPLRAKKGCSVTQLAFARKGIITPEMEYVAIRENQQLEEWIASFPIGGKTAEPFTAEFVRQEVAAGRAIIPANINHPELEPMIIGRNFRVKINANIGNSAMGSSIEEEVEKAVWACRWGADTVMDLSTGTNIHQTREWILRNSPVPIGTVPMYQALEKAGGVAENLTWELYRDTLVEQAEQGVDYFTIHAGILQEHLPAAGRRMTGIVSRGGAIMAKWCKTNNRENFLYTHFDEICEILRSYDIAISLGDALRPGCIADANDEAQFGELKVLGELTLLAWEHDVQVMIEGPGHVPLNLVEENMRKQLELCHGAPFYTLGPLITDIAAGYDHINSAIGGTLIAAYGCSMLCYVTPKEHLGLPDKNDVREGVVVHKVAAHAADIAKGNPTAWLQDELMSRARYAFAWEDQFNLSLDPVKARVLYAESRAASGQTDGNPDFCTMCGPDFCSMKRSQEK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Anaplasma phagocytophilum (strain HZ)

Length

557 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

61.561 kDa

Sequence

MHMNISEIYPSSNKIYINCTLYPDVKVGMRQINIRNSSQRFLLYDTAGPYTDCDIKVNLTEGISSIRRDWIARRNDTYPIRKAKTNSDARGVKALSGDDRVILKGIAGGAPVTQLFYAKKGIITPEMEYVAVRENALLEQAEAIPGLLLPTKTRKITPEFVREEVACGRAVIPSNINHPESEPMIIGRNFLVKINANIGNSAVLSNIEDEVKKMVLAVTYGADTVMDLSTGHDIHNIRELIVRNSPVPIGTVPIYQALNKVNGIVGDLSFEVFKETIIEQAEQGVDYFTIHAGVLKSYIEHTRSRTTGIVSRGGAIMAQWCLLHNKENFLYENFEEICEIMRSYDVTFSLGDGLRPGSINDANDVAQFLELRTLGELVKIARAHDCQVIVEGPGHVPMHLIEENVKKQLDFCDEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNAEDVKAGVISYKIAAHAADLAKGNPASFARDYALSQARYDFRWEDQFNLSIDPATAKKLHDESLPGKGGKTAHFCSMCGPKFCSMKLSKALND

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)

Length

556 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

61.332 kDa

Sequence

MNQENASCPKKHFFGPASSRITVKGTIYPIEVGMRRVALTRSYECKGERFDAMPLYDTSGPFGDAEREHDVRKGLEPVRDRWGFDRGTVESVGGELSMTGRKPRVAKAGEAVTQMHFARKGIVTPEMEYVAIRENQALEAWIEKCGGKPVTPEMVRSEVARGRAIIPANINHPEIEPMIIGRNFRVKINANIGNSALGSSIDEEVEKAVWSCRWGADTVMDLSTGKNIHQTREWILRNSPVPIGTVPLYQALEKVGGKAEELSWEVYRDTLVEQAEQGVDYFTIHSGILAATLPDAEARQTGIVSRGGSIMARWCRAHKQENFLFTRFDDICDILRSYDVAISLGDALRPGSIGDANDAAQFGELKTLGELTLRAWKRDVQVMIEGPGHVPLHMIRENMEMQLKHCHEAPFYTLGPLVTDVAAGYDHVNSAIGGTLIASLGCSMLCYVTPKEHLGLPNRDDVREGVIVHRVAAHAADIAKGSATAWLRDELMSKARYAFAWEDQFSLALDPLKTRQIHAQNIAATGDTSATAKYCTMCGPDFCSMKRSQETTAAGL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chlorobaculum parvum (strain NCIB 8327)

Length

555 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

61.268 kDa

Sequence

MNPESASCPDRHFFGPASSRMTVNGTIYPIEVGMRKVALKRTYECKGEPFNSMPLYDTSGPFGDPNGEHDVRKGLEPVRDRWGFDNGSAESTKGELSMSERKPRVAKSGEAVTQMHFARKGVITPEMEYVAIRENQALEEWIEKCGGKPVTPEMVRDEVAKGRAIIPANINHPEIEPMIIGRNFRVKINANIGNSALGSSIDEEVEKAVWACRWGADTVMDLSTGKNIHQTREWILRNSPVPIGTVPLYQALEKVGGKAEELSWEVYRDTLVEQAEQGVDYFTIHSGILAATLPDAEARQTGIVSRGGSIMARWCRAHNQENFLFTHFDDICDILRSYDVAVSLGDALRPGSIGDANDAAQFGELKTLGELTLRAWERDVQVMIEGPGHVPLHMIRENMELQLKHCHEAPFYTLGPLVTDVAAGYDHINSAIGGTLIASLGCSMLCYVTPKEHLGLPDRDDVREGVIVHRVAAHAADLAKGSHTAWLRDELMSKARYAFEWEDQFSLALDPLKTRQIHAQNIAATGDTAATAKFCTMCGPDFCSMKRSQETTAGM

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ehrlichia ruminantium (strain Gardel)

Length

555 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.384 kDa

Sequence

MKIDLNTIFPSSCKEYIPGKIYKNIKIGMRKVSFNNDTESILIYDTGGPHSDQDIQTNINNGIKKLRVNWITDRQDVEYYDRHTINTNSSTAFPLQNNKALKSKNDKPVTQMFYAKNNIITPEMEYVAIRENSLIQKLLSHTPNTIIPEITPELVRQEVAAGRAIIPANINHPESEPMIIGKNFLVKINANIGNSAVSSDINNEVYKMIYAIIYGADTVMDLSTGSHIHNTREWIIRNSPVPIGTVPIYQALNKVNGIVGELNFNIFKETLIEQAEQGVDYFTIHAGVLKKYIQYTTNRLTGIVSRGGAIIAQWCSIHNKENFLYTNFEEICDIMKSYDIAFSLGDGLRPGSIADANDKAQFLELKTLGELTDIAWKHDCQVMIEGPGHVPMHLIKENVEKQMYFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTSMLCYVTPKEHLGLPNLNDVKNGVITYKIAAHAADLAKGNPSAYIRDYALSYARFNFRWYDQFNLSLDPETAKSFHDESLPSEHAKSAHFCSMCGPKFCSMKLTHQLQLNSTE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ehrlichia ruminantium (strain Welgevonden)

Length

555 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.389 kDa

Sequence

MKIDLNTIFPSSRKEYIPGKIYKNIKIGMRKVSFNNDTESIFIYDTGGPHSDQDIQTNINNGIKKLRLNWITDRQDVEYYDRHTINTNSSTAFPLQNNKALKSKSDKPVTQMFYAKNNIITPEMEYVAIRENSLIQKLLSHTPNTIIPEITPELVRQEVAAGRAIIPANINHPESEPMIIGKNFLVKINANIGNSAVSSDINNEVHKMIYAIIYGADTVMDLSTGSHIHNTREWIIRNSPVPIGTVPIYQALNKVNGIVGELDFNIFKETLIEQAEQGVDYFTIHAGVLKKYIQYTTNRLTGIVSRGGAIIAQWCSIHNKENFLYTNFEEICDIMKSYDIAFSLGDGLRPGSIADANDKAQFLELKTLGELTDIAWKHDCQVMIEGPGHVPMHLIKENVEKQIYFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTSMLCYVTPKEHLGLPNLNDVKNGVITYKIAAHAADLAKGNPSAYIRDYALSHARFNFRWYDQFNLSLDPETAKSFHDESLPSEHAKSAHFCSMCGPKFCSMKLTHQLQLNSTE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Coxiella burnetii (strain CbuK_Q154)

Length

554 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.516 kDa

Sequence

MRREGTTRLHRTFLLRVYLKESAVITYPASKKIYCQGKIFPTIRVGMREIQLTNGDSLTLYDTSGPYSDPNISIKSPQGLPRLREPWIKVRPRKTQLAFAKEGVITPEMEYAAIRENQKRELKKNTDQERERRLQGNSLSARIPNPITPEFIRNEIACGRAILPANINHPESEPMIIGRHFLVKVNANIGNSSLTSSVEEEVEKLIWALRWGADTVMDLSTGKKIKEIRETILRHSPVPIGTVPLYEALEKVDGDVKALTWEIFRDTLISQAEQGVDYFTIHAGVLNRFIPLTQKRVTGIVSRGGSLMAKWCLLHREENFLYTHFTEICEIMRAYDVSFSLGDGLRPGSIADANDEAQFAELKIQGELNRIAWKYGVQVMNEGPGHIPLNLIEENMTKQLAYCREAPFYTLGPLTTDIAPGYDHIGSAIGAAFIAWQGCALLCYVTPKEHLGLPNKQDVKEGLIAYKIAAHAADLAKGHPAARQRDDLLSQARFEFRWHDQFNLALDAETARLFHDETLPKEAAKHAHFCSLCGPKFCAYKTSHEVRDTLQKVT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Coxiella burnetii (strain CbuG_Q212)

Length

554 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.516 kDa

Sequence

MRREGTMRLHRTFLLRVYLKESAVITYPASKKIYCQGKIFPTIRVGMREIQLTNGDSLTLYDTSGPYSDPNISIKSPQGLPRLREPWIKVRPRKTQLAFAKEGVITPEMEYAAIRENQKRELKKNTDQERERRLQGNSLSARIPNPITPEFIRNEIACGRAILPANINHPESEPMIIGRHFLVKVNANIGNSSLTSSVEEEVEKLIWALRWGADTVMDLSTGKKIKEIRETILRHSPVPIGTVPLYEALEKVDGDVKALTWEIFRDTLISQAEQGVDYFTIHAGVLNRFIPLAQKRVTGIVSRGGSLMAKWCLLHREENFLYTHFTEICEIMRAYDVSFSLGDGLRPGSIADANDEAQFAELKIQGELNRIAWKYGVQVMNEGPGHIPLNLIEENMTKQLAYCREAPFYTLGPLTTDIAPGYDHIGSAIGAAFIAWQGCALLCYVTPKEHLGLPNKQDVKEGLIAYKIAAHAADLAKGHPAARQRDDLLSQARFEFRWHDQFNLALDAETARLFHDETLPKEAAKHAHFCSLCGPKFCAYKTSHEVRDTLQKVT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Coxiella burnetii (strain Dugway 5J108-111)

Length

554 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.562 kDa

Sequence

MRREGTMRLHRTFLLRVYLKESAVITYPASKKIYCQGKIFPTIRVGMREIQLTNGDSLTLYDTSGPYSDPNISIKSPQGLPRLREPWIKVRPRKTQLAFAKEGVITPEMEYAAIRENQKRELKKNTDQERERRLQGNSLSARIPNPITPEFIRNEIACGRAILPANINHPESEPMIIGRHFLVKVNANIGNSSLTSSVEEEVEKLIWALRWGADTVMDLSTGKKIKEIRETILRHSPVPIGTVPLYEALEKVDGDVKALTWEIFRDTLISQAEQGVDYFTIHAGVLNRFIPLTQKRVTGIVSRGGSLMAKWCLLHREENFLYTHFTEICEIMRAYDVSFSLGDGLRPGSIADANDEAQFAELKIQGELNRIAWKYGVQVMNEGPGHIPLNLIEENMTKQLAYCREAPFYTLGPLTTDIAPGYDHIGSAIGAAFIAWQGCALLCYVTPKEHLGLPNKQDVKEGLIAYKIAAHAADLAKGHPAARQRDDLLSQARFEFRWHDQFNLALDAETARLFHDETLPKESAKHAHFCSLCGPKFCAYKTSHEVRDTLQKVT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

Length

554 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.594 kDa

Sequence

MRREGTMRLHRTFLLRVYLKESAVITYPASKKIYCQGKIFPTIRVGMREIQLTNGDSLTLYDTSGPYSDPNISIKSPQGLPRLREPWIKVRPRKTQLAFAKEGVITPEMEYAAIRENQKRELKKNTDQERERRLQGNSLSARIPNPITPEFIRNEIACGRAILPANINHPESEPMIIGRHFLVKVNANIGNSSLTSSVEEEVEKLIWALRWGADTVMDLSTGKKIKEIRETILRHSPVPIGTVPLYEALEKVDGDVKALTWEIFRDTLISQAEQGVDYFTIHAGVLNRFIPLTQKRVTGIVSRGGSLMAKWCLLHREENFLYTHFTEICEIMRAYDVSFSLGDGLRPGSIADANDEAQFAELKIQGELNRIAWKYGVQVMNEGPGHIPLNLIEENMTKQLAYCREAPFYTLGPLTTDIAPGYDHIGSAIGAAFIAWQGCALLCYVTPKEHLGLPNKQDVKEGLIAYKIAAHAADLAKGHPAARQRDYLLSQARFEFRWHDQFNLALDAETARLFHDETLPKEAAKHAHFCSLCGPKFCAYKTSHEVRDTLQKVT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)

Length

554 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

62.44 kDa

Sequence

MKIDFNTLFPSSTKEYISGTIYNNIKVGMRRIHINDNSESILTYDTGGPHTDQKIKIDINQGIEKIRLNWIVDRQDVEYHKRQEVNTNSEYAFPLQSNNILKANSNKPITQMYYARNNIITPEMEYVAIRENALRQKILSYKPTVMAPEITPEFVRQEIASGRAIIPANVNHPESEPMIIGKNFLVKINANIGNSVVSSSIEDELQKMIYAIIYGADTVMDLSTGNNIHNIREWIIRNSPVPIGTVPIYQALNKVNGVVGDLDFNIFKKTLIEQAEQGVDYFTIHAGVLKNYIDYTDNRLTGIVSRGGAIMAHWCTIHNKENFLYTNFEEICDIMKHYDITFSLGDGLRPGSIADANDTAQFLELKTLGELTDIAWKHDCQVMIEGPGHVPMHLIKENVEKQVHFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAIIGWYGTSMLCYVTPKEHLGLPNIQDVKDGVIAYKIAAHAADLAKGNPSAYIRDYALSYARFNFKWYDQFNLSLDPETAKSLHDESLPSENAKSAHFCSMCGPKFCSMKLTHQIKSIEE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Anaplasma marginale (strain St. Maries)

Length

553 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

60.759 kDa

Sequence

MDYSGVYPSSSKVYVRGNLYSDVNVGMRKVAIKNGTSEFLVYDTGGPYTDREAKLDIKSGIRKLRSTWIENRRDTSPVQRSFVPSGSSCTRYQKAAENVLRKIAGGSPVTQLFYAQNGIITPEMEYVAIRENALRMQVGSSETGAAAHQEITPEFVRQEIAAGRAIIPANINHPESEPMVIGRNFLVKINANIGNSAVLSGIEEEVKKMALAVAYGADTVMDLSTGSDIHNIREWIIRNSPVPIGTVPIYQALNKVKGVVENLSFEVFKETIIEQAEQGVDYFTIHAGVLKDYIKHARGRVTGIVSRGGAIMAQWCLAHNKENFLYTHFDEICEIMGSYDVAFSLGDGLRPGSIDDANDEAQFLELKTLGELVKVAWHHGCQVMVEGPGHVPMHLIKENMEKQLHLCSEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNIDDVKAGVISYKIAAHAADLAKGNPSAYARDYALSQARFDFRWYDQFNLSLDPLTAKSLHDESLPGKGGKTANFCSMCGPKFCSMKLSKELVDQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.898 kDa

Sequence

MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPITQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.898 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nocardia farcinica (strain IFM 10152)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.777 kDa

Sequence

MASADRVTAPVDTVTTGPIEGSVKHYREVDGLRIPVRRINLTNGETFDVYDTSGPYTDENATIDLEAGLPKLRDSWDKPTVAGPRTQLAWARAGIVTPEMRFIAAREGVEPELVRAEVAAGRAVIPANHNHPELEPTIIGKKFLVKINANIGNSAVSSSIAEEVEKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVNGDPAALTWEIYRDTVIEQAEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILARYDVTFSLGDGLRPGSVADANDEAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPHAQQRDDALSKARFEFRWRDQFALSLDPDTAREYHDETMPAEPAKTAHFCSMCGPKFCSMRISADVREYAEANNLTDVAAIEAGMAAKSAEFAESGGKVYLPVVS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.898 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium bovis (strain BCG / Pasteur 1173P2)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.898 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.898 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium leprae (strain Br4923)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.84 kDa

Sequence

MTETLSKTTEPSVTTGPIPGSSKAYREVANPDGGPSLRVPFRRVHLSTGAHFDLYDTSGPYTDPDAVINLTAGLPPRPGVIRDRGTQLQRARAGEITAEMAFIADREGMPAELVRVEVALGRAVIPANHNHPEIEPMIIGKAFAVKVNANIGNSAVTSSIAEEIDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTKLTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVLLTAKRVTGIVSRGGSIMASWCLANHRESFLYTNFAELCDIFARYDVTFSLGDGLRPGSIADANDTAQFAELRTLGELSKIAKVHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAVIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGYPRAQERDDALSTARFEFRWNDQFALSLDPPTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITADIRVYAAKHGLDTEEAIEMGMTEKSAEFAEHGNRVYLPLTQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium leprae (strain TN)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.84 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)

Length

547 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.898 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium ulcerans (strain Agy99)

Length

546 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.446 kDa

Sequence

MTVTVEPSITTGPIAGSSKAYREVAGPDGVTLRVPLRRVHLSTGADFDLYDTSGPYTDPNAVIDLAVGLPARPGLVRDRGTQLQRARAGEITAEMAFIAAREGMSAELVRDEVALGRAVIPANHNHPESEPMVIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWELYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDILARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEPAKTAHFCSMCGPKFCSMRITRDVRDYAAKHGLDSEEAIEAALEAGMAEKSAEFADHGNRVYLPITQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)

Length

546 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.945 kDa

Sequence

MSTPSSRSQAPETVTTGPIQGSEKIYQELPNGLRVPQRRVNLTNGEYLDLYDTSGPYTDTNAVIDLHKGLPPRAGIVTDRGTQLQRARAGEITAEMEFIAVREGVPAELVRTEVAAGRAVIPANHKHPESEPMIIGKAFGVKINANIGNSAVTSSIAEEVEKMVWAIRWGADNIMDLSTGKDIHQTREWILRNSPVPVGTVPIYQALEKTNGDPAALTWELYRDTVIEQAEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILARYDVTFSLGDGLRPGSIADANDEAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVKLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHSADLAKGHPRAQLRDNALSKARFEFRWEDQFNLSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITADIREFAAENGLETQEDIDAMLARGMEEKSAEFAEHGNRVYLPIA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M)

Length

546 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.418 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)

Length

544 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

60.84 kDa

Sequence

MTNVTENITCPVKRIECIPPEKIYSKGTIFPLEVGMKRVKLSKTYFCNGQEFSSLPLYDTGGPYSDPSVSIDPEKGLPPIRKSWGFQRDEKAASSITQMHFARKGIITPEMEYVSIRENQQLEEWISSFSRGGAKVSPITPEFVRQEIAEGRAIIPANINHPELEPMIIGRKFRVKINANIGNSALGSSIEEEVEKAVWSCRWGADTVMDLSTGANIHQTREWILRNSPVPIGTVPMYQALEKAGGKAEALTWELYRDTLIEQAEQGVDYFTIHAGILLEHLPFAEKRLTGIVSRGGSIMAKWCKYHKEENFLYTRFEEICKILQRYDIAVSLGDALRPGSIIDANDEAQFGELKVLGELTKVAWKYEVQVMIEGPGHVPLHMIRENMDKELAYCHEAPFYTLGPLITDIAAGYDHINSAIGGALIASFGCSMLCYVTPKEHLGLPDRNDVREGVIAHKVAAHGADLAKGNPVSWLQDELMSRARYSFAWEDQFNLSLDPEKIRAVHAQSMAARGHTEKNPHFCTMCGPDFCSMKKSKEAAEQE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium avium (strain 104)

Length

540 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.251 kDa

Sequence

MTAIVEPSVTTGPIAGSSKVYRELDGVPGARVPFRRVHLSTGDHFDLYDTSGPYTDPDATIDLTAGLPARPGRVRDRGTQLQRARAGEITAEMAFIAAREGMPAELVRDEVARGRAVIPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEWCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAAMADKSREFAEHGNRVYLPLAQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)

Length

540 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.25 kDa

Sequence

MTAIVEPSVTTGPIAGSSKVYRELDGVPGARVPFRRVHLSTGDHFDLYDTSGPYTDPDATIDLTAGLPARPGRVRDRGTQLQRARAGEITAEMAFIAAREGMPAELVRDEVARGRAVIPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEWCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAGDLAKGHPHAQQRDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAAMADKSREFAEHGNRVYLPLAQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Chlorobium chlorochromatii (strain CaD3)

Length

531 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

59.332 kDa

Sequence

MSKAPLFEKISVKGTLFPIEVSMKRLHLSHPYTCNGQEFSSLPMYDTSGLHGDCRTQVDPHVGLPPLRSSWNFPRTVQLGVAQTQMHYARKGVITPEMEYVAIRENQQLEEWIRSFNRHGKKVEPITPEFVRQEIAAGRAIIPANLKHPELEPMIIGRHFRVKINSNIGNSAMGSSIEEEVEKAVWSCRWGADTVMDLSTGANIHQTREWILRNSPVPIGTVPVYQALEKAGGKAENLTWELYRDTLIEQAEQGVDYFTIHAGILQEHLPYAERRLTGIVSRGGSIMATWCRHHQQENFLYTHFNDICEILKSYDIAVSLGDALRPGSILDANDEAQFGELKVLGELTKQAWQHEVQVMIEGPGHVPLNLIEENMQKELELCYEAPFYTLGPLITDIAAGYDHINSAIGGALLASLGCSMLCYVTPKEHLGLPDRNDVREGVIAHKVAAHGADIARGNPTAWLRDTLMSQARYSFAWEDQFNLSLDPEKTRAVHSQSIAASGYSAPNPDFCTMCGPDFCSMKRTQKMGKGN

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)

Length

511 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

57.751 kDa

Sequence

MESTQEFQVPLKTIRLTDGTEYQSYHTEGSLSDKKPSDYKNGIPKIRKEWIRTRLDRGDTNHSQMYYAKKGIITEEMRYVALRENMNPEFVRLEIACGRAILPSNRNHPELEPMIIGRNFLVKINANIGNSALGSSIEEEVEKLHWAVKWGADTVMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVKGKAENLNIQVFLDTLEERAEQGVDYFTIHAGVLLHYIPFTANRVTGIVSRGGSILAKWCLAHHKENFLYTHFDEIIKVMKKYGVSFSLGDGLRPGSIADANDKAQFGELETLGELTKRAWEEDIQVMIEGPGHVPMHLIKENVDLQMKLCQEAPFYTLGPLVTDIAPGYDHITSAIGAAMIGWFGMAMLCYVTPKEHLGLPDKEDVKQGVIAYKIAAHAADLAKGHPGAIKRDNLLSKARFEFRWEDQFALSLDPETAKSFHDETLPQDRMKTAHFCSMCGPHFCSMNLTQELRKFAQEKGMEEKSEVTICNRKKESGK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)

Length

511 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

57.698 kDa

Sequence

MESTQEFQVPLKTIRLTDGTEYQSYHTEGSLSDKKPSDYKNGIPKIRKEWIRTRLDRGDTNHSQMYYAKKGIITEEMRYVALRENMNPEFVRLEIACGRAILPSNRNHPELEPMIIGRNFLVKINANIGNSALGSSIEEEVEKLHWAVKWGADTVMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVKGKAGNLNIQVFLDTLEERAEQGVDYFTIHAGVLLRYIPFTANRVTGIVSRGGSILAKWCLAHHKENFLYTHFDEIIKVMKKYGVSFSLGDGLRPGSIADANDKAQFGELETLGELTKRAWEEDIQVMIEGPGHVPMHLIKENVDLQMKLCQEAPFYTLGPLVTDIAPGYDHITSAIGAAMIGWFGMAMLCYVTPKEHLGLPDKEDVKQGVIAYKIAAHAADLAKGHPGAIKRDNLLSKARFEFRWEDQFALSLDPETAKSFHDETLPQDRMKTAHFCSMCGPHFCSMNLTQELRKFAQEKGMEEKSEVTICNRKKESGK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)

Length

495 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

55.975 kDa

Sequence

MEPVQKLQIPYKSIRLSDGTEYQSYHTEGALSGKQPADYKNGIPAFRKEWIQKRFNHSNHSQMYFAKKGIITEEMRYAAFRENMEPEFVRSEIACGRAILPSNRNHPELEPMVIGKNFLVKINANIGNSTFSSSIEEEVEKLHWAIKWGADTVMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVKGKTENLNIQIFLETLEEQAEQGVDYFTIHAGVLLRYIPLTTNRITGIVSRGGSILAKWCQAHHKENFLYTHFDEILKVMKKYGVSISLGDGLRPGSIADANDKAQFSELETLGELTQLAWKEDIQVMIEGPGHVPMNLIKENVDLQTKICQEAPFYTLGPIVTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKEDVKQGVIAYKIAAHAADLAKGHPGAIDRDNLLSKARFEFRWEDQFSLSLDPETAKTFHDEMLPQDRMKTAHFCSMCGPHFCSMNLTQELRKFAQEKEIQES

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)

Length

495 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

55.989 kDa

Sequence

MEPVQKLQIPYKSIRLSDGTEYQSYHTEGALSGKQPADYKNGIPAFRKEWIQKRFNHSNHSQMYFAKKGIITEEMRYAAFRENMEPEFVRSEIACGRAILPSNRNHPELEPMIIGKNFLVKINANIGNSTFSSSIEEEVEKLHWAIKWGADTVMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVKGKTENLNIQIFLETLEEQAEQGVDYFTIHAGVLLRYIPLTTNRITGIVSRGGSILAKWCQAHHKENFLYTHFDEILKVMKKYGVSISLGDGLRPGSIADANDKAQFSELETLGELTQLAWKEDIQVMIEGPGHVPMNLIKENVDLQTKICQEAPFYTLGPIVTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKEDVKQGVIAYKIAAHAADLAKGHPGAIDRDNLLSKARFEFRWEDQFSLSLDPETAKTFHDEMLPQDRMKTAHFCSMCGPHFCSMNLTQELRKFAQEKEIQES

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Trichodesmium erythraeum (strain IMS101)

Length

486 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

53.897 kDa

Sequence

MRTEWIAKRSGHKNVSQMHYGRQGIITEEMNFVAQRENLPAELIRAEVARGRMIIPANINHTNLEPMCIGIASRCKVNANIGASPNTSDITKEVDKLKLSIKYGADTVMDLSTGGGNLDEIRTAIINASPVPIGTVPVYQAVESVHGRIENLTADDFLHVIEKHAQQGVDYQTIHAGILIEHLPLVRSRITGIVSRGGGIIAKWMLHHHKQNPLYTHFDDIIEIFKKYDVSFSLGDSLRPGCTHDASDEAQLAELKTLGQLTRRAWGHEVQVMVEGPGHVPMDQIEFNVKKQMEECSSPPLNALDLDPLASNANEQMEKFNVLGPAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIGRHRQGARDRDDELSAARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKEKEVVTQS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain CC9605)

Length

484 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

53.363 kDa

Sequence

MIHGQTSTPGLSVAPQIMRASWVESRKGQANVSQMHYARQGVVTEEMAHVAKRENLPESLVMEEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNASDAAEEVKKLKLAVKYGADTVMDLSTGGVNLDEVRTAIIGASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLYHHRQNPLYTRFDDICEIFKRYDCTFSLGDSLRPGCQHDASDAAQLAELHTLGELTRRAWKHDVQVMVEGPGHVPLDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNADDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDEDLEGLEKVLEANTGAAELTPVKLDKAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain WH8102)

Length

483 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

53.489 kDa

Sequence

MIEQAVADLWLPIAVLIMRASWVSPRKGQANVSQMHYARQGVVTEEMAYVAKRENLPESLVMEEVARGRMIIPANINHTGLEPMAIGIASKCKVNANIGASPNASDAAEEVNKLKLAVKYGADTVMDLSTGGVNLDEVRTAIIDASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHRQNPLYTRFDDICEIFKRYDCTFSLGDSLRPGCQHDASDAAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPLDQIEFNVKKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITEEDIEGLEKVLEARGAAELTPVKLDKAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Length

480 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

52.09 kDa

Sequence

MTQMAAARNGTVTEEMERVAEREGVDPAFVRQQVADGQAVIPANVGHDSLDPMIIGREFATKVNANIGNSEETSDIEGELEKLHTAVHYGADTVMDLSTGRNLDEIRSANVTHSPVPVGTVPIYEAVKRASDPSEITHELLLDVIEKQAKQGVDYMTIHAGVRMEHLPLTDGRKTGIVSRGGSILAKWIEENGMENPLYTKFEAICEIFREYDVTFSLGDGLRPGCLADAGDDAQFAELDTLGELTRTAWKHDVQVMVEGPGHVPMDQVAEQVERQQEVCDGAPFYVLGPLVTDVAPGYDHITSAIGATEAGRAGAAMLCYVTPKEHLGLPEKSDVRDGLAAYRIAAHAADVANGREGARDWDDALSEARYAFDWREQFDLALDPDRAREYHDQTLPGDNYKEARFCSMCGVEFCSMRIDQDARSDGDMESIEADADDRTPLEDSSAAAVNRPPVGTHDGADIPGPDADMPADTEGSADD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)

Length

477 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.518 kDa

Sequence

MTTQLQHARGGTVTDAMERVAERENRDAEFVRQQVADGQAVIPANHGHDALDPMIIGREFATKVNANIGNSEPASGPEAELQKLHTAVHYGADTVMDLSTGGDLDTIRTENIAYSPVPVGTVPIYEAVTRVDDASDLTPELLLDVVEKQAEQGVDYMTLHAGVLAEHLPLTDGRTTGIVSRGGSILARWMEEHGEQNPLYERFDDLCEILAAYDVTVSLGDGLRPGSLADASDAAQFAELDTLGELTRRAWDHGVQVMVEGPGHVPMDEIADNVERQQDVCDGAPFYVLGPLVTDVAPGYDHITSAIGATEAARAGAAMLCYVTPKEHLGLPDAEDVRDGLAAYRIAAHSADVANGRPGARDWDDAVSEARYAFDWRRQFELALDPGRARNYHDQTLPEDNYKEARFCSMCGVEFCSMRIDQDAREAGDGMDGLESRTDLDSSAAAAVNRPPTGVHRAEKLDDIPCPVAEDDVAADD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)

Length

476 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.384 kDa

Sequence

MSTQLQHARDGTVTDAMRRVADREGRDPEVVREAVADGHAVIPANHHHDALDPMIIGRDFATKVNANIGNSDTTGDIDDELEKLHTAVHYGADTVMDLSTGENLDGIRTANIDNSPVPVGTVPIYEAVTRVEDVTDITPDLLIDVVEKQAKQGVDYMTLHAGVLAEHLPLTDDRTTGIVSRGGSILSQWMTEHGEQNPLYTHYDELCEILQAHDVTISLGDGLRPGSVADASDDAQFAELDTLGELTRRAWDHGVQAMVEGPGHVPMDQIRANVDRQQEVCDGAPFYVLGPLVTDIAPGYDHITSAIGATEAARAGAAMLCYVTPKEHLGLPDAEDVRDGMAAYRIAAHAGDVAAGKPGARDWDDALSEARYNFDWNRQFDLALDPERAQAFHDQTLPGDNYKDARFCSMCGVDFCSMRIDQDARDAGDDADDMTELTTETDLSESAAAEVNRPPTGTHDAPAAEQAPSPGDDDDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)

Length

476 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.384 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)

Length

468 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

52.246 kDa

Sequence

MIMRTSWVASRKGQSNVSQMYFARREVITEEMSFVAKKENLPESLIMEEVARGRMIIPANINHLNLEPMAIGIASSCKVNANIGASPNASDVNEELKKLHLAVKYGADTVMDLSTGGVNLDEVRTAIIQASPVPIGTVPVYQALESVHGSIEKLSEEDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHKQNPLFTRFDDICEIFKRYDCSFSLGDSLRPGCLHDASDEAQLAELKTLGELTQRAWKHDVQVMVEGPGHVPMDQIEFNVRKQMEDCLEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADIARHRSGARDRDDELSRARYAFDWNKQFELSLDPERAREYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDKDLENLESILSSKGAKEINTMKLDKEV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Anaeromyxobacter sp. (strain Fw109-5)

Length

468 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.626 kDa

Sequence

MRAQWIARRHGQPNVTQMHHARRGSVTEEMAHVAAREKLDPELVRQEVARGRMVIPANLKHPELEPIAIGIAATCKINANIGNSAVTSDVDEELRKLSVCLRHGADTVMDLSTGGDIPLIRENILRHSPIPVGTVPIYECLAHVKDVVDLTPRGLLEIIEAQAAQGVDYMTIHAGVLRDIVPMAAGRITGIVSRGGALLARWMAANGQENPLYTHFDEICEIFKRYDVTFSLGDGLRPGCLADASDEAQFAELKVLGELTRKAWAHDVQVMVEGPGHVPLDQIPMNMQKERELCDEAPFYVLGPLVTDIAPGYDHITSAIGAAVAAQHGASMLCYVTPAEHLGLPDAEDVRQGIVAYKIAAHAADVARQRPGARDRDDALSRARYAFDWKRQFELSLDPDAARTKHDATLPQEAAKSAEFCSMCGPKFCSMRIHSHLGDGAAPGAALPCADAAPSQPTRAGGPLPIAR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain WH7803)

Length

467 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.609 kDa

Sequence

MRASWVESRRGQANVSQMHFARQGVVTEEMAYVAKRENLPESLVMEEVARGRMIIPANINHTGLEPMAIGIASKCKVNANIGASPNASDAAEEVNKLKLAVKYGADTVMDLSTGGVNLDEVRTAIIDASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHRQNPLFTRFDDICEIFKRYDCTFSLGDSLRPGCQHDASDAAQLAELKTLGELTRRAWAHDVQVMVEGPGHVPLDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDEDLEGLEKVLETKSGAADLAGVKMEKES

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain RCC307)

Length

466 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.652 kDa

Sequence

MRSAWIEKRRGSANVSQLHYARQGVVTEEMAYVAKRENLPESLVMEEVARGRMIIPANINHANLEPMAIGIASKCKVNANIGASPNASDASEEVKKLELAVKYGADTVMDLSTGGVNLDEVRTAIINASPVPIGTVPVYQALESVHGSIERLSEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHKQNPLYTRFEDICEIFKRYDCTFSLGDSLRPGCQHDASDDAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNADDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYAFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDKDLESLEEVLKAKGGAELSTAKLDRAD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain CC9902)

Length

466 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.517 kDa

Sequence

MRTQWVSARKGQANVSQMHYARKGVVTEEMAYVAKRENLPESLIMEEVARGRMIIPANINHTNLEPMAIGIASSCKVNANIGASPNASDAAEEVNKLKLAVKYGADTVMDLSTGGVNLDEVRTAIIGASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLYHHRQNPLFTRFDDICEIFKRYDCTFSLGDSLRPGCQHDASDAAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPLDQIEFNVKKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYAFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDEDLEGLQKVLESQGAAELASVKLDKAE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain NATL1A)

Length

466 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

52.069 kDa

Sequence

MRNSWVASRKGKTNVSQMHFARKGEITEEMRYVAKRENLPESLVMEEVARGRMIIPANINHINLEPMAIGIASTCKVNANIGASPNASDISEELKKLDLAVKYGADTLMDLSTGGVNLDEVRTEIINASPIPIGTVPVYQALESVHGSISRLNEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLYHYKQNPLFTRFDDICEIFKRYDCTFSLGDSLRPGCLHDASDEAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADVARHRSGARDRDDELSKARKEFDWNKQFELSLDPEKAKQYHDETLPEEIFKKAEFCSMCGPNHCPMNTKITDEDLDQLNDQIQSKGAAELTPVKLNKEN

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain NATL2A)

Length

466 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

52.101 kDa

Sequence

MRNSWVASRKGKTNVSQMHFARKGEITEEMRYVAKRENLPESLVMEEVARGRMVIPANINHMNLEPMAIGIASTCKVNANIGASPNASDISEELKKLDLAVKYGADTLMDLSTGGVNLDEVRTEIINASPIPIGTVPVYQALESVHGSISRLNEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLYHYKQNPLFTRFDDICEIFKRYDCTFSLGDSLRPGCLHDASDEAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADVARHRSGARDRDDELSKARKEFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPNHCPMNTKITDEDLDKLNDQIQSKGAAELTPVKLNKEN

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain CC9311)

Length

465 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.333 kDa

Sequence

MRTEWVSARKGQANVSQMHYARKGVVTEEMAYVAKIENLPESLVMEEVARGRMIIPANVNHTNLEPMAIGIASKCKVNANIGASPNASDAAEEVNKLKLAVKYGADTVMDLSTGGVNLDEVRTSIIGASSVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHRQNPLFTRFDDICEIFKRYDCTFSLGDSLRPGCQHDASDAAQLAELKTLGDLTRRAWKHDVQVMVEGPGHVPLDQIEFNVKKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYAFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDADLDGLEQVLKSQGAAELVGVKQDKL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)

Length

463 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.212 kDa

Sequence

MRADWIAKRRGQANVSQMHYARSGVVTEEMAFVAARERLEPELVRAEVARGRMVIPANVRHPELEPLAIGITACCKINANIGNSAVTSNIDEELAKLRVCLKYGADTVMDLSTGGDIPQIREAILRASPIPVGTVPIYECLAHVKDVADLTPELMLEIIEAQAAQGVDYMTIHAGVLRDFIPLAAHRITGIVSRGGALMAQWMLANKAENPFFTHFEQICEIFKRYDVTFSLGDGLRPGCLADASDAAQFAELKALGDLTRKAWEHGVQVMVEGPGHVPLDQIPMNMEKERELCSEAPFYVLGPLVTDIAPGYDHITSAIGAAVAAQHGAAMLCYVTPAEHLGLPDIDDVREGIVAYKIAAHAADVARHRPGARDRDDALSRARYAFDWNKQFELSLDPDTARAKHDETLPHEAFKSAEFCSMCGPKFCSMKIHGHLAEAAAAQDAAANGEAEKPAGGLQVLP

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Anaeromyxobacter dehalogenans (strain 2CP-C)

Length

463 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.21 kDa

Sequence

MRADWIAKRRGQANVSQMHYARDGVVTEEMAFVAARERLEPELVRAEVARGRMVIPANVRHPELEPLAIGIEACCKINANIGNSAVTSNIDEELAKLRVCLKYGADTVMDLSTGGDIPQIREAILRASPIPVGTVPIYECLAHVKDVADLTPELMLEIIEAQAAQGVDYMTIHAGVLRDFIPLAAHRITGIVSRGGALMAQWMLANKAENPFFTHFEQICEIFKRYDVTFSLGDGLRPGCLADASDAAQFAELKALGDLTRKAWEHGVQVMVEGPGHVPLDQIPMNMEKERELCSEAPFYVLGPLVTDIAPGYDHITSAIGAAVAAQHGAAMLCYVTPAEHLGLPDIDDVREGIVAYKIAAHAADVARHRPGARDRDDALSRARYAFDWNKQFELSLDPDTARAKHDETLPHEAFKSAEFCSMCGPKFCSMKIHGHLAEAAAAQDEAANGAAAKPAGGLQVLP

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Anaeromyxobacter sp. (strain K)

Length

463 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.082 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)

Length

461 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.297 kDa

Sequence

MRADWVAKRQGQSNVSQMHYARQGVITEEMDYVAKRENLPVDLIRDEVARGRMIIPANINHTNLEPMCIGIASKCKVNANIGASPNSSEINEELAKLQQAVKYGADTVMDLSTGGGNLDEIRTAIIKASPVPIGTVPIYQALESVHGNMENLTANDFLHIIEKHAQQGVDYMTIHAGILIEHLPLVKNRITGIVSRGGGILARWMLHHHKQNPLYTHFDDIIEIFKRYDVSFSLGDSLRPGCTHDASDEAQLAELKTLGQLTRRAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPDAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSHARYNFDWEKQFELSLDPERAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKYLASTAAKEELAKA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermosynechococcus elongatus (strain BP-1)

Length

461 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.298 kDa

Sequence

MVRSEWIAARKGHDNVTQMHYARQGIITEEMHYVAQRENLPPELIRDEVARGRMIIPANINHPNLEPMAIGIAAKCKVNANIGASPNSSNLEEELAKLRLAVKYGADTVMDLSTGGGDLDAIRTAIINASPVPIGTVPVYQALESVHGSVERLTPDDFLHVIEKHAQQGVDYMTIHAGLLIEYLPLVKNRITGIVSRGGGILAKWMLYHHKQNPLYTHFRDIIEIFKKYDVSFSLGDSLRPGCLHDASDEAQLAELKTLGQLTRKAWEHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAALAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNRQFELALDPERAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDAEALAELEKFLAKDKDQVSASA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH)

Length

461 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

52.197 kDa

Sequence

MRTEWIKKRMNDKTRTQMYYAKKGIITEEMEYVAKEENLDPELVRSEVARGRLIIPANINHKHLKPMAIGRVSKTKVNSNIGASALASDIEEEVRKLETSVKYGADTVMDLSAGAKNMDEIREAIIAASPVPIGTVPMYQIIDEIGDVLELTYDDILRVLEKQAKQGVSYFTIHAGLLLRHMPEIAKRKMGIVSRGGSLTASWMLKHHKENPFYTIFDDILDICKEYDVSLSLGDSLRPGCLYDASDKAQLEELKVLGELTLRAWDKDVQVMIEGPGHVPINEIERNVRLEQIYCHEAPFYVLGPLVLDIGAGYDHIGSAIGAAMAAWYGVSMLCYVTPKEHLGLPNEEDVREGMLAYKIAAHSADIARKIPGARDKDDEMSDARYKFDWKKQFELALDPERAKEYHDETLPQEVFKEAEFCSMCGPKFCSYKVTQDAMENFDWDEFKKEAEEKMKAEANN

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Solibacter usitatus (strain Ellin6076)

Length

461 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.798 kDa

Sequence

MRTDWVAKRKNDPIRTQMHYARKGIITEEMHYIAKRESISPELIRSEVARGRMIIPANVNHANLEPMCIGVASKCKINSNIGNSSVVSDIAGELEKLEYSVKYGADTVMDLSTGGDIPAIRKAIIGASPIPIGTVPIYEALSRVRRVEDLSAQVMLEVIEEQAEQGVDYMTIHAGILVQHIPLTTKRVTGIVSRGGSILAEWMVKNHKQNFLYECFEDICKILQKHDVSFSLGDGLRPGSIADASDAAQFAELKTLGELTQVAWKHDVQTMIEGPGHIPMDQIEMQVIKEKELCFEAPFYTLGPLVTDIAPGYDHITSAIGAAMIGWYGASMLCYVTPKEHLGLPNREDVKAGIIAYKIAAHAADIARHRPGVRDRDDALSRARYRFDWKEQFALSLDPETARSMHDETLPEDGFKDAHFCSMCGPKFCSMNISAKVESFTADDAAAVLSGAAPESLVNIE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Microcystis aeruginosa (strain NIES-843)

Length

460 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.097 kDa

Sequence

MRQEWVAPRRGQANVSQMHYARQGIITEEMTYVAKRENLSPELIRSEIARGRLIIPANINHLNLEPMAIGIASKCKVNANIGASPNSSNINEELEKLHLAVKYGADTVMDLSTGGGNLDEIRTAIINASPVPIGTVPIYQAVESVHGNIEKLTPEDFLHIIEKHAGQGVDYMTIHAGILIEHLPLVKTRLTGIVSRGGGIIAKWMLHHHKQNPLYTHFDEIIEIFKRYDVSFSLGDSLRPGCTHDASDAAQLAELKTLGQLTRRAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAALAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSIARYNFDWNRQFQLSLDPDRAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADAITELEKFLASQNQDNLTPV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cyanothece sp. (strain PCC 8801)

Length

460 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.317 kDa

Sequence

MRSQWVAKRRGQSNVSQMHYARQGMITEEMDYVAKRENLPPDLIRQEVARGRMIIPANINHLNLEPMAIGIASKCKVNANIGASPNSSNLEEEVAKLNLAVKYGADTVMDLSTGGGDLDTIRTAIINASPVPIGTVPIYQAVESVHGNIEKLTPDDFLHIIEKHAQQGVDYMTIHAGLLIEYLPLVRSRLTGIVSRGGGIIAKWMLHHHKQNPLYTHFDEIIEIFKKYDVSFSLGDSLRPGCTHDASDEAQLSELKTLGQLTRRAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPDAEDVRNGLIAYKIAAHAADIARQRPGARDRDDELSKARYNFDWNRQFELSLDPDRAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAEQKNKEAIAH

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251)

Length

460 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.246 kDa

Sequence

MRSLWVEKRKDDPVKTQMYYAKQGIITQEMEYVAKIEKLSPELIRSEIARGRLIIPANVNHTTLEPMAIGIAATCKINANIGSSAIASDVQGEVEKMQVSQHYKADTAMDLSTGGDLDEIRKAVIASSKIPIGTVPIYQILHDVGNKIEDLSIEVMLEVLERQAKQGVSYFTIHAGFLLETMPKIAKRKMGIVSRGGSLMAAWMMHYHRENPFYTAYDEILDICARYDVALSLGDSLRPGCLADASDDAQLGELKVLGELTLRAWEKNVQVMIEGPGHVPLNQIERNMKLQRELCHEAPFYILGPLVTDIAAGYDHISSAIGAAVGGWHGASMLCYVTPKEHLGLPNANDVREGIIAYKIAAHAADIARGRKGARDIDDEMSDARYRFDWNRQFELALDSERAREYHDETLPQDVFKEAEFCSMCGPKFCSYKITQSIMDNPEAIEQIAREVKEREALGA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)

Length

459 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.648 kDa

Sequence

MLRTEWIARRHGHANVSQMYYARQGLITEEVAYVAHRENLEPELVRSEVARGRLIIPANTNHPNLEPMGIGIATRCKVNANIGASPNASNLGEEVAKLELAVKYGADTVMDLSTGGGDLDAIRSAIIQASPVPIGTVPMYQALEAVHGNVEKLTPEHILDVIEKHAKQGVDYMTIHAGILIEHLPLTQGRLTGIVSRGGGILARWMLAHHKQNPLYTHFDEIINIFKKYDVSFSLGDSLRPGCQHDASDAAQFAELKTLGELTRRAWTHDVQVMVEGPGHVPMHQIEMNVRKQMQECSEAPFYVLGPLVTDIAPGYDHITSAIGAALAGWYGTAMLCYVTPKEHLGLPNAEDVRTGLIAYKIAAHAADIARGRPGARDRDDELSRARYNFDWNRQFELSLDPERAREYHDETLPADIYKSAEFCSMCGPKFCPMQTKIDSQALSELEAALKPQPVAAQE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Length

459 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.137 kDa

Sequence

MRTAWVAKRQGQTNVSQMHYARKGVITEEMDYVAKRENLPVELIKDEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNSSNIDEEVEKLLLSVKYGADTVMDLSTGGGDLDVIRTAIINASPVPIGTVPIYQALESVHGSIENLTPDDFLHIIEKHAQQGVDYMTIHAGLLIEYLPLVKSRITGIVSRGGGIIAKWMLHHHKQNPLYTHFDEIIEIFKKYDVSFSLGDSLRPGCTHDASDDAQLSELKTLGQLTRRAWEHDVQVMVEGPGHVPIDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAIAGWHGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSKARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDAEMLEELEVFLAKDKEMVSQR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain MIT 9303)

Length

459 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.834 kDa

Sequence

MRASWVAARKGQANVSQLHFARQGVVTQEMDYVARRENLPESLVMEEVARGRMIIPANINHANLEPMAIGIASSCKVNANIGASPNASDVAEELKKLELAVKYGADTVMDLSTGGVNLDEVRTAIINASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPLVKGRLTGIVSRGGGILAQWMLYHHRQNPLFTRFDDICEIFKRYDCSFSLGDSLRPGCQHDASDAAQLAELKTLGELTKRAWAHDVQVMVEGPGHVPMDQIEFNVRKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKQYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDEDLEGLEKSLKSKGKAELPA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain MIT 9211)

Length

459 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.961 kDa

Sequence

MRASWVANRQGKSNVSQLHFARQGMITEEMAYVANRENLPESLVMEEVARGRMIIPANINHLNLEPMAIGIASKCKVNANIGASPNASDVGEELKKLELAVKYGADTVMDLSTGGVNLDEVRTAIINASPVPIGTVPVYQALESVHGSIEKLSEEDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHKQNPLFSRFDDICEIFKRYDCSFSLGDSLRPGCLHDASDEAQLAELKTLGQLTKRAWAHDIQVMVEGPGHVPMDQIEFNVRKQMEDCSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADIARHRSGARDRDDELSKARYAFDWNKQFELSLDPERARQYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDKDLDDLEDVIKSKDASKINL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain MIT 9313)

Length

459 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.853 kDa

Sequence

MRASWVAARKGQANVSQLHFARQGVVTQEMDYVAKRENLPESLVMEEVARGRMIIPANINHENLEPMAIGIASSCKVNANIGASPNASDVAEELKKLELAVKYGADTVMDLSTGGVNLDEVRTAIINASPVPIGTVPVYQALESVHGSIEQLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPLVKGRLTGIVSRGGGILAQWMLYHHRQNPLFTRFDDICEIFKRYDCSFSLGDSLRPGCQHDASDAAQLAELKTLGELTKRAWAHDVQVMVEGPGHVPMDQIEFNVRKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKQYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDEDLEGLEKSLKSKGKAKLSA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cyanothece sp. (strain ATCC 51142)

Length

459 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.22 kDa

Sequence

MRTQWVAKRRGQNNVSQMYYARQGVMTEEMDYVAKRENLPPELIREEVARGRMIIPANINHTNLEPMCIGIASKCKVNANIGASPNSSNLDEEVAKLNLAVKYGADTVMDLSTGGGDLDAIRSAVIKASPVPIGTVPIYQALESVHGNIENLTPDDFLHIIEKHAQQGVDYMTIHAGILIEHLPLVRSRLTGIVSRGGGIIARWMLHHHQQNPLYTHFDEIIEIFKKYDVSFSLGDSLRPGCTHDASDEAQLAELKTLGQLTRRAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPDAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSKARYNFDWNRQFELSLDPDRAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAQKDKEKVAQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cyanothece sp. (strain PCC 7424)

Length

459 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.364 kDa

Sequence

MRAEWIAKRRGQSNVSQMHYARQGVITEEMHYVANRENLPVDLIRDEVARGRMIIPANINHVNLEPMCIGIASQCKVNANIGASPNSSDINEELEKLRLAVKYGADTVMDLSTGGGDLDTIRTAIINDSPVPIGTVPIYQALESVHGRIENLTPDDFLHIIEKHAQQGVDYMTIHAGILMEYLPLVRNRLTGIVSRGGGIIAKWMLHHHKQNPLYTHFDDIIEIFKKYDVSFSLGDSLRPGCLHDASDEAQLSELKTLGQLTRRAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADVARHRQGARDRDDQLSNARYNFDWNRQFELSLDPDRAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKDKETVSQS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Acaryochloris marina (strain MBIC 11017)

Length

458 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.137 kDa

Sequence

MRHQWVANRRGQSNVSQMHYARQGQITEEMDYVAKRENLPADLIREEVARGRMIIPANVNHVNLEPMAIGIASKCKVNANIGASPNSSNIEEELDKLRLAVKYGADTVMDLSTGGGNLDEIRTAIINESSVPIGTVPIYQALESVHGNIENLTADDFLHIIDKHAQQGVDYQTIHAGILIEHLPLVRDRITGIVSRGGGILARWMLHHHKQNPLYTRFNDVIEIFKKHDVSFSLGDSLRPGCTHDASDDAQLAELKTLGQLTRRAWEHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPDAEDVRNGLIAYKIAAHAADIARHRPGARDRDDQLSEARYNFDWNRQFELSLDPERAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKDQVGSAR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Cyanothece sp. (strain PCC 7425 / ATCC 29141)

Length

458 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.054 kDa

Sequence

MRREWVAKRQGHANVSQMHYARQGIITEEMDYVAKRENLPAELIRDEVARGRMIIPANINHLNLEPMAIGIASKCKVNANIGASPNSSNLEEEVAKLNLAVKYGADTVMDLSTGGGNLDQIRTAIINASPVPIGTVPIYQALESVHGTIEKLTPDDFLHVIEKHAQQGVDYMTIHAGILIEYLPLVRNRITGIVSRGGGIIARWMLHHHKQNPLYTHFRDIIEIFKKYDVSFSLGDSLRPGCQHDASDEAQLSELKTLGQLTRKAWEHNVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAALAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSKARYNFDWNRQFELALDPDRAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKQPTGTSV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Helicobacter hepaticus (strain ATCC 51449 / 3B1)

Length

457 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.083 kDa

Sequence

MRTQWVQQRADDKIRTQLHYAKKGIITKEMEYVANIENISAELIRQEIERGRLIIPANINHTNLKPMGIGIATRTKINSNIGSSSLASSIDEEVEKVKVSIKYGADTIMDLSTGGDLDEIRTAVIQASSVPIGTVPIYQILYDVKNDILQLDIDTMLSVLKKQAKQGVSYFTIHCGFLLSHMPFVAKRKMGIVSRGGSLMASWMMHYHKENPFYEYFDEILKICQEYDVSLSLGDSLRPGCLADASDEAQFAELKVLGELAKRAWKADVQVMIEGPGHVPLNQIERNVELQKQYCNHAPFYVLGPLVTDIAAGYDHIASAIGACVAAWKGVAMLCYVTPKEHLGLPNAKDVREGILAYKIAAHAADIARGRIGARDRDDAMSDARYSFDWNRQFELALDPDRAREYHDEALPQEVFKDAEFCSMCGPKFCSYKISQDIFKAHNAKESEDTQPLASNQ

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium tetani (strain Massachusetts / E88)

Length

457 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.403 kDa

Sequence

MRESLKLSLFYFNKKERNKMNYTTQMDAAKRGIVTKEMETIAKKEGIDVKKIIECVAKGSVAIPANKNHKSLSAEGVGQGLRTKINVNLGISKDCCNVDRELEKVKKAIDMKAEAIMDLSCFGKTQEFRKRLIEMSPAMIGTVPMYDAIGFYDKELKDITAEELLDVIETHAKDGVDFMTIHAGLNREAVEIFKRNERLTNIVSRGGSLLYAWMELNNKENPFYEHFDKVLDICEKYDVTISLGDACRPGSIHDSTDASQIKELMTLGELTKRAWERNVQIIIEGPGHMSLDEIETNMKLEKKLCYNAPFYVLGPIVTDIAPGYDHITSAIGGAIAATYGADFLCYVTPAEHLRLPDLDDMKEGIIATKIAAHAADIAKGIKGAREWDNKMSVARKELDWEKMFDLAIDNEKARKYRKNSTPEVNDSCTMCGKMCAVRNMNKVMQGKDINILRNEDK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nostoc punctiforme (strain ATCC 29133 / PCC 73102)

Length

457 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.974 kDa

Sequence

MRTEWVAKRRGQVNVSQMHYARQGVITEEMHYVAQRENLPTDLIRDEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNSSNLQEEVDKLNLAVKYGADTVMDLSTGGGNLDEIRTAIIKASPVPIGTVPVYQALESVHGTIENLTADDFLHIIEKHAQQGVDYQTIHAGILIEHLPLVRNRITGIVSRGGGILARWMLHHHKQNPLYTHFQDIIEIFKRYDVSFSLGDSLRPGCTHDASDEAQLAELKTLGQLTRKAWEDDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSKARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKEPVTQS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)

Length

457 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.813 kDa

Sequence

MRTEWVAKRRGQGNVTQMHYARQGVITEEMQYVARRENLPADLIREEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNSSNLQEEVDKLNLAVKYGADTVMDLSTGGGNLDEIRTAIINASPVPIGTVPVYQALESVHGTIENLTPDDFLHIIEKHAQQGVDYQTIHAGILIEHLPLVRSRITGIVSRGGGILARWMLHHHKQNPLYTHFGDIIEIFKRYDVSFSLGDSLRPGCTHDASDDAQLAELKTLGQLTRKAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSKARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKEPVTQG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937)

Length

457 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.016 kDa

Sequence

MRTEWVAKRRGQGNVTQMHYARQGVITEEMQYVAQRENLPADLIREEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNSSNLQEEVDKLNLAVKYGADTVMDLSTGGGNLDEIRTAIINASPVPIGTVPVYQALESVHGTIENLTPEDFLHIIEKHAQQGVDYQTIHAGILIEHLPLVRSRITGIVSRGGGILARWMLHHHKQNPLYTHFRDIIEIFKRYDVSFSLGDSLRPGCTHDASDDAQLAELKTLGQLTRKAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSKARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKEKEVMI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Aquifex aeolicus (strain VF5)

Length

457 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.049 kDa

Sequence

MLRAEWVEKRKRFKNKTQMHLARQGIITEEMEYVAKREGLHPEFVRQEVARGRMIIPANINHLHLEPMCIGINSKVKVNANIGNSGLASDIPTEVEKAKVAIKYGADTIMDLSTGEAIKETREAIINVSTVPVGTVPIYEAWKIAKGNVKELTVDLILDVIEEQARQGVSYMTIHAGILREHLPLVQHRVMGIVSRGGAILAQWMAEHGKQNPLYEHFDKICEIFKKYDVSFSLGDALRPGCIEDATDDAQLAELKVLGELVEKAWKHDVQAMVEGPGHVPLHQVEFNMKIQQEWCHEAPFYVLGPLVLDVAPGYDHIGSAIGGALAGWAGAAMLCYITPKEHLGLPNVEDVKQGVIAYKIAAHAADIAKHWPGARDWDLAMSIARYNFDWNKQFELAMDPETARAYHDETLPQEGYKTAKFCSMCGPEFCSYKISQKVQEKVSPEELIENGNWVAP

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.83 kDa

Sequence

MRSDWIAPRRGQANVTQMHYARQGVITEEMDFVARRENLPADLIRDEVARGRMVIPANINHTNLEPMAIGIASKCKVNANIGASPNASNIDEEVEKLKLAVKYGADTVMDLSTGGGNLDEIRTAIINASPVPIGTVPVYQALESVHGRIEKHSADDFLHVIEKHCEQGVDYQTIHAGLLIEHLPKVKSRITGIVSRGGGIIAQWVLYHHKQNPLYTHFRDIIEIFKRYDCSFGLGDSLRPGCLHDASDDAQLSELKTLGQLTRVAWEHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSRARYAFDWNKQFDLSLDPERAREYHDETLPADIYKTAEFCSMCGPKHCPMQTKITEEDLTELEKFLEKDSALA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain MIT 9215)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.028 kDa

Sequence

MRSSWIKPRLGKNNVTQMNFARNGYLTEEMDFVAKKENLPSSLIMEEVARGRLIIPANINHLNLEPMSIGIASRCKVNANIGASPNASDINEEVEKLKLAVKYGADTVMDLSTGGVNLDEVRQAIIQESPVPIGTVPVYQALESVHGSIDRLTEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLHHFKQNPLYTRFDDICEIFKKYDCTFSLGDSLRPGCLHDASDDAQLAELKTLGELTRRAWEHNVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTSMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRAGARDRDDELSYARYNFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPKHCPMNSKISDESLDQLKDKLEECNTSA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain MIT 9515)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.889 kDa

Sequence

MRNSWIKPRLGQKNITQMNFAKNGIITEEMNYVAQKENLPSSLIMEEVARGRLIIPANINHVNLEPMAIGIASKCKVNANIGASPNASDINEEVEKLRLAVKYGADTVMDLSTGGVNLDEVRQAIIKESSVPIGTVPVYQALESVHGSIDRLTEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLHHFKQNPLYTRFDDICEIFKKYDCTFSLGDSLRPGCLHDASDDAQLAELKTLGELTRRAWAHNVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRAGARDRDDELSHARYTFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPKHCPMNSKISDETLDQLNNKLAKCDIKV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain MIT 9312)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.992 kDa

Sequence

MRSSWIKPRLGKDNVTQINFARNGYITEEMDFVAKKENLPASLIMEEVARGRLIIPANINHLNLEPMSIGIASRCKVNANIGASPNASDINEEVEKLKLAVKYGADTVMDLSTGGVNLDEVRKAIIHESPVPIGTVPVYQALESVHGSIDRLTEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLHHFKQNPLYTRFDDICEIFKKYDCTFSLGDSLRPGCLHDASDDAQLAELKTLGELTRRAWEHNVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTSMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRAGARDRDDELSHARYNFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPKHCPMNSKISDESLDQLKDKLEECNSSV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.874 kDa

Sequence

MRNSWIQPRIGQKNITQMNFAKNGHITEEMNYVAKKENLPPSLIMEEVARGRLIIPANVNHVNLEPMAIGIASKCKVNANIGASPNASDINEEVEKLKLAVKYGADTVMDLSTGGVNLDEVRQAIIKESSVPIGTVPVYQALESAHGSIERLTEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLHHFKQNPLYTRFDDICEIFKKYDCTFSLGDSLRPGCLHDASDDAQLAELKTLGELTRRAWTHNVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRAGARDRDDELSHARYNFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPNHCPMNSKISDETLDELNNKLTKCDTSV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain AS9601)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

51.031 kDa

Sequence

MRSSWIKPRLGKDNVTQMNFARNGYITEEMDFVAKKENLPSSLIMEEVARGRLIIPANINHLNLEPMSIGIASRCKVNANIGASPNASDINEEVEKLKLAVKYGADTVMDLSTGGVNLDEVRQAIIQESPVPIGTVPVYQALESVHGSIDRLTEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLHHFKQNPLYTRFDDICEIFKKYDCTFSLGDSLRPGCLHDASDDAQLAELKTLGELTRRAWEHNVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTSMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRAGARDRDDELSHARYNFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPKHCPMNSKISDESLDQLKDKLEECNTSV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Prochlorococcus marinus (strain MIT 9301)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.972 kDa

Sequence

MRSSWIKPRLGKDNVTQMNFARNGYITEEMDFVAKKENLPPSLIMEEVARGRLIIPANINHLNLEPMSIGVASRCKVNANIGASPNASDINEEVEKLKLAVKYGADTVMDLSTGGVNLDEVRQAIIQESPVPIGTVPVYQALESVHGSIDRLTEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLHHFKQNPLYTRFDDICEIFKKYDCTFSLGDSLRPGCLHDASDDAQLAELKTLGELTRRAWEHNVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTSMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRAGARDRDDELSHARYNFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPKHCPMNSKISDESLDQLKDKLEECSTSA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus elongatus (strain PCC 7942)

Length

456 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.882 kDa

Sequence

MRSDWIAPRRGQANVTQMHYARQGVITEEMDFVARRENLPADLIRDEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNASNIDEEVEKLKLAVKYGADTVMDLSTGGGNLDEIRTAIINASPVPIGTVPVYQALESVHGRIEKLSADDFLHVIEKHCEQGVDYQTIHAGLLIEHLPKVKSRITGIVSRGGGIIAQWMLYHHKQNPLYTHFRDIIEIFKRYDCSFSLGDSLRPGCLHDASDDAQLSELKTLGQLTRVAWEHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSRARYAFDWNKQFDLSLDPERAREYHDETLPADIYKTAEFCSMCGPKHCPMQTKITEEDLTELEKFLEKDSALA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain JA-3-3Ab)

Length

455 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.738 kDa

Sequence

MRSEWVARRRGQANVTQMHFARQGVITEEMDYVARRENLPPELIRSEVARGRMIIPANINHTNLEPMCIGIASRCKVNANIGASPSSSGLAEELEKLKLAIKYGADTVMDLSTGGGDLDEIRTAIIQASPVPIGTVPIYQALESVHGNVEKLSAEDILHIIEKQAQQGVDYMTIHAGILIEYLPLVRNRLTGIVSRGGGILARWMLAHHKQNPLYTHFRDIIEIFKKYDVSFSLGDALRPGCLHDASDEAQMAELKTLGQLTRMAWEHDVQVMVEGPGHVPMDQIEFNVRKQMEECDEAPFYVLGPLVTDIAAGYDHISSAIGAALAGWYGAAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDEMSRARYNFDWNRQFELSLDPERAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKMDAEALSELERFLAKQPTA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Synechococcus sp. (strain JA-2-3B'a(2-13))

Length

455 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.66 kDa

Sequence

MRSEWVARRRGQANVTQMHFARQGVITEEMEYVAQRENLPPELIRSEVARGRMIIPANINHTNLEPMCIGIASRCKVNANIGASPTSSGLAEELEKLKLAIKYGADTVMDLSTGGGDLDEIRTAIIQASPVPIGTVPIYQALESVHGKVEKLSAEDILHVIEKQAQQGVDYMTIHAGILIEYLPLVRHRLTGIVSRGGGILARWMLAHHKQNPLYTHFRDIIEIFKKYDVSFSLGDSLRPGCLHDASDEAQLAELKTLGQLTRMAWEHDVQVMVEGPGHVPMDQIEFNVRKQMEECDEAPFYVLGPLVTDIAAGYDHISSAIGAALAGWYGAAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDEMSRARYNFDWNRQFELSLDPERAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKMDAEALSELEQFLAAQPTG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Campylobacter fetus subsp. fetus (strain 82-40)

Length

450 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

50.172 kDa

Sequence

MRKDWCEARKNDPTPTQMYYAKNGVITPEMEYVAKVEMLKPEYIRQLVAEGKLIIPANINHTNQIPMAIGRAVKCKINANIGSSALASDINEEIEKLKVCLKYGADTVMDLSTGGDLDEIRRAIIANSTVPIGTVPIYQIIHDIKDLDNLTPQIMLECIEKQAKQGVSYFTIHAGFLLKFMPLVAKRKMGIVSRGGSLMASWMMKHHKENPFYEAFDEICDICAKYDASLSLGDSLRPGCLHDASDEAQMSELAVLGELTKRAWEKNVQVMVEGPGHVPFNQIEFNMKEEKRLCHDAPFYILGPLPTDIGAGYDHITSAIGGTMAAFHGASMLCYVTPKEHLGLPNAKDVRDGIISHKIAAHAADIALGRVGAIERDHAMSDARYKFDWNKQFELALDPDKARELHDESLPQDVFKEAEFCSMCGPKFCAYKISQEIAKIECSDYPKEKK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A)

Length

449 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

49.885 kDa

Sequence

MRSQWLKNRKNDKTPTQMYYAKNGIITEEMRYVAKIEQMDAEILRSEVARGKTIIPANINHTNLVPMGIGRSLKCKINSNIGSSSVSSGVEEEVEKLKISIKYGADTVMDLSTGGDLNEIRTQIIKNSTVPIGTVPIYQIIHDVGSIENLTISQMLKTIENQAIQGVSYFTIHAGFLLEFMPLVAKRKMGIVSRGGSLMATWMMKNHKENPFFTAFDEILEICAKYDVSLSLGDSLRPGCIYDASDAAQISELKILGDLARRAWTKNVQVMIEGPGHVPFNEIASNMQLERVLCDDAPFYVLGPLPTDIGAGYDHITSAIGGTMAAFSGASMLCYVTPKEHLGLPNAKDVREGIVAHKIAAHIADVALGKKGAIERDHAMSDARYNFDWNKQFELSLDPDRAKEYHDETLPQEVFKEAEFCSMCGPKFCAYKISREISKNSCEFYKECK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)

Length

449 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

49.657 kDa

Sequence

MRQSWIEKRKNDSVRTQLHYARAGIITEEMQAVANVEGLSEELIRSEVARGRLVIPANIHHLSLSPMGIGVAARTKINANIGSSSLASCIEEEIEKTLVSIKYGADTIMDLSTGGDLDAIRCAVIEHSSVPIGTVPIYQILHDVQGDIKNLTIDSMLEVMERQARQGVSYFTIHCGFLLEHLPKVAKRKMGIVSRGGSLMASYMMHYHKQNPFYEAFDEILAICREYDVTLSLGDSLRPGCLADASDEAQLAELKVLGELTLRAWEKDVQVMIEGPGHVPMNQIERNVKLQKELCHEAPFYVLGPLVTDIAAGYDHIASAIGAAIAAWKGVAMLCYVTPKEHLGLPNAKDVREGILAYKIAAHAADIARGRIGARDRDDAMSDARYAFDWNRQFELALDPDRAKEYHDESLPQEVFKEAKFCSMCGPKFCSYKISQEIVSKHASGESLT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Nitratiruptor sp. (strain SB155-2)

Length

444 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

49.72 kDa

Sequence

MRKEWVEKRKKDSVRTQMYYARQGIVTEEMEYVAKVEGLDPELIRKEVARGRMIIPANINHLHQKPMAIGIAAKCKINANIGSSALASDAAGEVEKVKVCQKYGADTIMDLSTGGDLDAIREEVIKHAEVPIGTVPIYQILHDCNNKIEDLTIDKMLEVIERQAQQGVSYFTIHAGFLLRFMPLVAKRKMGIVSRGGSLMAAWMMHYHKENPFYTAFDDILDICRKYDVSLSLGDSLRPGCLADASDDAQLEELKVLGELTLKAWDKDVQVMIEGPGHVPMNQIERNIKIERDYCHEAPFYVLGPLVTDIAAGYDHLASAIGAAMAGWYGASMLCYVTPKEHLGLPNAEDVREGIVAYKIAAHAADIARGRKGARDVDDAMSDARYKFDWNKQFELALDPDRAREYHDETLPQDVFKEAEFCSMCGPKFCSYKITQDILEKHGA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)

Length

441 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.602 kDa

Sequence

MTQLLSARAGEITPEMEYVAKREDLPVELIRDEVASGRMVIPANKVHAAGALEPMAIGIAAKCKINANIGNSAVTSNVGEELEKLHTAVHFGADTVMDLSTGKDIDNIRRQIIDKSPVPIGTVPIYQMLEELGGNIEDMNAQHFLDMVEHQAKQGVDYMTIHCGVKLEHLHLTVNRVTGIVSRGGSLIAKWMMAHNKQNPLLEAFDDLCDIMREYDVTWSLGDGLRPGSIADASDDAQFAELDVLGECTKRGWEKGTQVMVEGPGHIPLDQIQMNIERQIEVCHGAPFYVLGPLVTDIAPGYDHITSCIGAANAGMHGAAMLCYVTPKEHLGLPNEEDVKQGVIAYKIAAHTADVARKRKGAQDRDDALSKARFAFDWKEQFRLSLDPETAQRYHDETLPQDTFKSAHFCSMCGPKYCSMKITEDIRQMAKEKKLVELPTT

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)

Length

439 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.37 kDa

Sequence

MTIYKDARNGRITEEMKKIAEVEGVDPEFVRRGLAAGRIVLLRNLKRADRVKTVAVGEGMLTKVNANIGTSNTLIDVNMEVEKAKIAKKYGADTVMDLSTGGNLDVIRRKIMEAAEPLPLGTVPIYQAFMDVATRKGAGLYMTEDDILNTIEKHLKDGVDFMTLHAALTRDLAAKAVKSDRAEPIVSRGGSILAAWMLEHGKENPLLSNFDYILEMFKEYDAVISLGDSLRPGALEDAHDEYHLSELMVNARLVKRAREAGVQVMLEGPGHVPLDRVVADVKLAKRLTEGAPYYILGPLVTDIAAGYDHIAGAIGGAIAAAHGADFLCYVTPAEHLNLPNPEQVREGVIAFRIAAHAADIVKYPDRAMKVDIEMGRCRGRLDWECMIRLSLDPDKAREIRNQYGPTSIKSCNMCGSLCVFLLLDKWRRKKDEELHAPLA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium botulinum (strain ATCC 19397 / Type A)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.859 kDa

Sequence

MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIASKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium botulinum (strain 657 / Type Ba4)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.901 kDa

Sequence

MNYTTQMDAAKKGIVTKEMEIVAKKENMDVKDLMELISKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYERFDELLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIASKIAAHAADLAKGVKGARDLDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.859 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium botulinum (strain Kyoto / Type A2)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.816 kDa

Sequence

MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRTMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIEINMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIASKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium botulinum (strain Okra / Type B1)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.872 kDa

Sequence

MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMKLVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIATKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.872 kDa

Sequence

MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFNKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIATKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium botulinum (strain Loch Maree / Type A3)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

49.003 kDa

Sequence

MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHVENGADFLTIHVGMNRKTASTFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYERFDELLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWDRNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIATKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium kluyveri (strain NBRC 12016)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.725 kDa

Sequence

MNFTTQMDAAKKGIITKEMKVVSQKEGVDVEILRELVAEGKIVIPANKNHKSLDAQGVGQGLKTKINVNLGISKDCANIDMELEKVKTAIEMKAEAIMDLSSYGKTEEFRKRIVEMCSVMIGTVPIYDAVGFYDKELSDISPEEFLAVVEKHAQDGVDFMTIHAGINRETAKVFKRNKRLTNIVSRGGSLLYAWMELNNKENPFYEYYDKVLDICARYDVTISLGDACRPGSINDSTDASQIKELITLGELTKRAWEKNVQVIVEGPGHMSLNEIAANMQLEKKLCHGAPFYVLGPLVTDIAPGYDHITSAIGGAIAAANGADFLCYVTPAEHLRLPNLEDMKEGIIASKIAAHAADVSNNIKGAKEWDYKMSEARKELNWEKMFDLAIDPEKARRYRRESTPEHEDTCTMCGKMCAVRNMNKVMEGKNINILREED

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.725 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium novyi (strain NT)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.862 kDa

Sequence

MNYTTQMDAAKRGIVTKEMEIVAKKECMEISKLMNLVATGQVAIPANKNHKSLSPEGVGQDLKTKINVNLGISKDCYNIDAELEKVKKAVEMKAEAIMDLSCYGKTEEFRRKLIDMSPAMIGTVPMYDAIGFYDKELKDITAEELLAVVEKHAKDGVDFMTIHCGINRETAEVFKRNPRLMNLVSRGGSLLFAWMQLNNKENPFYEHFDKVLDICEKYDVTISLGDACRPGCIEDSTDPSQIKELITLGELTKRAWERNVQIIIEGPGHMSLSEIKTNMLLEKKLCHNAPFYVLGPIVTDVAPGYDHITSAIGGAIAASFGADFLCYVTPAEHLRLPNIDDMKEGIIATKIAAHAADIAKGIPGARDWDNKMSRARRDLDWDTMFELAIDPEKAKRYRAESIPEDEHTCTMCGKMCAVRNMNKVMDGKNINILREDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Alkaliphilus metalliredigens (strain QYMF)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.798 kDa

Sequence

MNYTTQMDAARKGLVTKEMEAVARKEGMDIEILRERVATGKIAIPANKNHHSLDAEGIGEGLRTKINVNLGISKDCPNIEVELDKVRTALEMKAEAIMDLSSFGKTEEFRKSLIEMSPAMIGTVPIYDAVGFYDKELQDITAQEFIDVVEKHAKEGVDFVTIHAGMNQETAAVFKRNPRLTNIVSRGGSLLYAWMELNKKENPFYQYYDQLLEICEKYDVTISLGDACRPGSIHDATDASQIKELMVLGELTLRAWEKNVQVMIEGPGHMAIDEIAANMVLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAASHGADFLCYVTPAEHLRLPTLEDMKEGIIASKIAAHAGDIAKKVPGARKWDNEMSRARQQLNWEKMFELAIDPEKARRYREESKPEHDDSCTMCGKMCSMRNMNKIMEGKNINILREDD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Alkaliphilus oremlandii (strain OhILAs)

Length

437 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.75 kDa

Sequence

MKYTTQMDAARKGIITKEMEIVSKKENMDIEILREKMAKGQIVIPANKNHKSLDPEGIGSGLKTKINVNLGISRDCPNVDAELEKVKIAIDMKAEAIMDLSSFGKTEEFRQKLVNMSTAMIGTVPIYDAVGFYDKELKDITEKEFLDVVRKHGEDGVDFVTIHAGLNRDTVKTFKKNTRVTNIVSRGGSLLYAWMELNNKENPFYEYYDELLEICAAYDMTISLGDALRPGSIADGTDASQIAELMVLGELTKRAWEKNVQVIIEGPGHMKLNEIEANVILEKKLCHGAPFYVLGPLVTDIAPGYDHITSAIGGAIAASHGVDFLCYVTPAEHLRLPTLEDMKEGIIASKIAAHAGDLAKGVQGADEWDLKMSKARQKLDWEEMFSLSIDDEKARRYRKESSPEHEDSCTMCGKMCSMRNMNRIMEGKDINILRSED

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)

Length

436 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.495 kDa

Sequence

MDYTTQMDAAKKNVTTKEMEVVAEKEQMEISELKMLMAEGKIVIPANKNHKSLSAEGVGQGLKTKINVNLGISKDCQNVDMEMKKVEIAIAMKAEAIMDLSSFGKTEEFRKKLINMSKAMIGTVPIYDAIGFYDKELKDITAEEMIGVVEKQAKEGVDFMTIHAGINRETAETFKRNKRAMNIVSRGGSLLYAWMELNNKENPFYEYYDKILDICEKYDVTISLGDACRPGCIDDSTDASQITELIKLGELTKRAWDRNVQVMVEGPGHMALNEIQSNMIIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAVAAASGADFLCYVTPAEHLRLPNIEDMKEGIVASKIAAHAADIAKNVKGARDWDNKMAEARQKLDWKAMFDLSIDPEKAIRYRKESTPEDPDTCTMCGKMCSVRNMNKVMAGKDVNILRED

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)

Length

436 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.004 kDa

Sequence

MATTQLEYARQGIITDKMKEAALAEGVSPEFIREGIAAGTIIICHNIKHGNGRPLAVGKGLRTKVNANIGTSADDTDITKELEKARVAVRHGADAIMDLSTGGPVDEIRRAIIAETNACIGSVPLYQAALDAVRTKKKAIVDMTVDDIFEGIIKHAEDGVDFITVHCGVTRSTVERMKNEGRLMDVVSRGGAFTVEWMAYNNCENPLFEHFDRLLEITKAYDMTLSLGDGFRPGCLADATDRAQIHELIILGELTQRAQAAGVQVMIEGPGHVPLNQIEANILLQKRLCHGAPFYVLGPLVTDIAPGYDHITCAIGGAIAASAGADFLCYVTPSEHLRLPSVEDVREGVIASRIAAHAADIAKGVKGAMEKDIAMAKCRKKLDWEGQFNLSLDPEKAQRLRAESGVAEHGACTMCGEFCAYKVMDDAMEKQRAAGH

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)

Length

436 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.718 kDa

Sequence

MNYTTQMDAAKKGIITKEMQVVSEKEGINIETLMNLMAEGKIVIPANKNHKSISAEGVGQGLRTKINVNLGISKDCANIELELEKVKKAIDMNAESIMDLSNYGKTYDFRKRLVEVSTAMIGTVPMYDVVGFYDKELKDITVDEFFEVVEKHAKDGVDFVTIHAGLNRETIETFRRNKRLTNIVSRGGSLLFAWMELNNRENPFYEYFDRLLDICEKYDLTLSLGDACRPGSIADATDAVQIKELITLGELTKRAWERNVQVIIEGPGHMAMNEIEANVLLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAMAASYGADFLCYVTPAEHLRLPNLEDVREGIVATKIAAHAADIAKGISGARDIDNKMSDARKRLDWDEMFSLAIDSEKAIRYRKESTPEHKDSCTMCGKMCSIRNMNKILEGKDINLLRED

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium perfringens (strain 13 / Type A)

Length

436 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.718 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Clostridium perfringens (strain SM101 / Type A)

Length

436 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.66 kDa

Sequence

MNYTTQMDAAKKGIITKEMQVVAEKEGINIETLMNLMAEGKIVIPANKNHKSISAEGVGQGLKTKINVNLGISKDCANIELELEKVKKAIDMNAESIMDLSNYGKTYDFRKRLVEVSTAMIGTVPMYDVVGFYDKELKDITVDEFFDVVEKHAKDGVDFVTIHAGLNRETIETFRRNKRLTNIVSRGGSLLFAWMELNNRENPFYEYFDRLLDICEKYDLTLSLGDACRPGSIADATDAVQIKELITLGELTKRAWERNVQVIIEGPGHMAMNEIEANVLLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAMAASYGADFLCYVTPAEHLRLPNLEDVREGIVATKIAAHAADIAKGISGARDIDNKMSDARKRLDWDEMFSLAIDSEKAIRYRKESTPEHKDSCTMCGKMCSIRNMNKILEGKDINLLRED

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)

Length

435 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.585 kDa

Sequence

MTQLEAARKGKITEEMAYVAEKEGVSPEFVREGVAAGRIVIPRNPNHKTLTDFKGIGEGLSVKVNANLGTSYDYVNVEEEVEKARVAIQYGADTVMDLSTGGDLKAIRKRILEVATVPLGTVPIYEAEFRAARRKNFFDMSADELFQVIEEHGKEGVDYITVHVGVTLKNLEVYRNSPRTTGIVSRGGGLMAAWMLHRGEENPLYARFDDLLDIARTYDMTLSLGDGLRPGSLADSTDRAQIAELLTIGELVERARRAGVQAMVEGPGHIPLNEVAANVQIQKKLTGHAPFYILGMLPVDTAAGFDHIAGAIGGALAGWWGADMLCYLTPAEHLGLPTPEHVKQGVIAFKIAAHAADVARGNKRALERNRRMSEARYRLDWEGQFALALFPEEARRLKEERGSKTKACSMCGPFCPMNLVEAVLKGKGRMELPVA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Length

435 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.586 kDa

Sequence

MTQLEAARKGKITEEMAYVAEKEGVSPEFVREGVAAGRIVIPRNPNHKTLTDFKGIGEGLSVKVNANLGTSYDYVDVEEEVEKARVAIQYGADTVMDLSTGGDLKAIRKRILEVATVPLGTVPIYEAEFRAARRKNFFDMSADELFQVIEEHGKEGVDYITVHVGVTLKNLEVYRNSPRTTGIVSRGGGLMAAWMLHRGEENPLYARFDDLLDIARTYDMTLSLGDGLRPGSLADSTDRAQIAELLTIGELVERARRAGVQAMVEGPGHIPLNEVAANVQIQKKLTGHAPFYILGMLPVDTAAGFDHIAGAIGGALAGWWGADMLCYLTPAEHLGLPTPEHVKQGVIAFKIAAHAADVARGNKRALERNRRMSEARYRLDWEGQFALALFPEEARRLKEERGSKTKACSMCGPFCPMNLVEAVLKGKGRMELPVA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Desulfotalea psychrophila (strain LSv54 / DSM 12343)

Length

434 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.957 kDa

Sequence

MTRNLEKKMSIREDAQQGKVTPLFEQCAAVESMSVERLMAGVSDGTIAITKNKNHAFSKVIAIGAGTSTKVNANLGSSKDINSLEEELKKLAVAIKAGADTIMDLSMGGDLQKIRQEILKNCSVPLGTVPIYQVAAEVVAAGKEIVDMTVERMFEVIEQQAKDGVDFMTIHCGINRHLQERLKNQPRTMGVVSRGGSFTLDWMNHHKRENPMYEYFDDLLAILKEHEVTLSLGDGIRPGCLADATDRNQIQELITLGELTERAWAAGVQVIVEGPGHMPLNQIKANVLLQKQMCKGAPFYVLGPLVTDIAPGYDHITGAIGGAIAASAGADYLCYVTPAEHLKLPNCSDVHEGVIASKIAAHAADIVKGLPGAIEKDNAMAKCRKELDWKGQIELSIDPAKSAQYRHEGGGDATDACSMCGEFCALKVFERSQK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Finegoldia magna (strain ATCC 29328)

Length

433 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.559 kDa

Sequence

MEYTTQLDAAKKKIITKEMKRVAQKENIDVEILREKIEKGYVVIPANKNHKSLDAHGVGEGLKTKINVNLGISKDCYNIEKEMEKVRVAIDMDAEAIMDLSNYGKTRKFREELIGYSPAMIGSVPMYDCVGMLDKELKDITEEEFLEVVEQHAKDGVDFITIHVGLTRDIAQHLKTTDRITKIVSRGGSLLFAWMIVNNKENPLVTRYDDILEICEKYDVTLSLGDALRPGCINDATDDLQIQELINLSRMAKRAYEKNVQVMIEGPGHVPIDQIEANMKIEKTICNNAPFYVLGPLVTDIAPGYDHITSAIGGAIAASTGADFLCYVTPAEHLRLPNLEDMKEGIIATKIAAHAGDIAKKIPGAKERDDEMSRARFNLDWEKMFELAIDSEKPKKYRKESQPIEEDSCTMCGKMCSMRTVKKVLNGEDVNLI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)

Length

433 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.269 kDa

Sequence

MYKTQMEAAKKGILTKEMKSIAESESIDEKVLMERVASGEITIPANKKHSSLLAKGVGTGLSTKINVNLGISKDCPNVDKELEKVKVAIDMKVDAIMDLSSFGKTEEFRKKLITMSTAMVGTVPVYDAIGFYDKELKDIKAEEFLDVVRKHAEDGVDFVTIHAGLNREAVNLFKRNERITNIVSRGGSLMYAWMELNNAENPFYENFDKLLDICEEYDMTISLGDALRPGCLNDATDACQIKELITLGELTKRAWERNVQIIIEGPGHMAIDEIEANVKLEKKLCHNAPFYVLGPLVTDIAPGYDHITSAIGGAIAAAAGVDFLCYVTPAEHLRLPDLDDMKEGIIASRIAAHAADISKKVPKAIDWDNRMAKYRTDIDWEGMFTEAIDEEKARRYRKESTPENEDTCTMCGKMCSMRTMKKMMSGEDVNILK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Peptoclostridium difficile (strain 630)

Length

433 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

48.451 kDa

Sequence

MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVIPANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSNYGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFITIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEYDVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIEANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHLRLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPEKAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sulfolobus islandicus (strain M.16.27)

Length

433 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.654 kDa

Sequence

MGIIDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKGLTTKVNVNIGTSSEVVDLDMELQKVKVANKWGDTLMDLSTGGDLDAIRRDIIKASDLPVGTVPVYQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKNALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRVAAHAGDVVKLGRKARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMDQVRKIGSSSSL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)

Length

433 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.641 kDa

Sequence

MGIIDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKGLTTKVNVNIGTSSEVVDLDMELQKVKVANKWGDTLMDLSTGGDLDAIRRDIIKASDLPVGTVPVYQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKSALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVKLGRKARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMDQVRKIGSSSSL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)

Length

433 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.641 kDa

Sequence

MGIIDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKGLTTKVNVNIGTSSEVVDLDMELQKVKVANKWGDTLMDLSTGGDLDAIRRDIIKASDLPVGTVPVYQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKSALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVKLGRKARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMDQVRKIGSSSSL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)

Length

433 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.74 kDa

Sequence

MGIIDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKRLTTKVNVNIGTSSEVVDLDMELQKVKVANKWGDTLMDLSTGGDLDAIRRDIIKASDLPVGTVPVYQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKSALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVKLGRKARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMDQVRKIGSSSSL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.801 kDa

Sequence

MTQLEYALSGIVTKEMKIVAEYEGVDEEFILEGVKKGEIVIPSNINHKNLIPKGIGRGLSTKVNANIGTSDAYPEIEKEIEKLNVAVKAGADAVMDLSTGGDINQSCRKILENSPVPVGTVPMYQAAVESISKYGSIVAMPEEFIFEVIEEQAKDGVDFITVHCGLTFESLKKLKDNGRVMDIVSRGGSFTIAWMLHNNKENPLYKHFDRLLDIAKKYDITLSLGDGLRPGCLEDATDAAQIQELIILGELVKKSREAGVQVMVEGPGHVPIDQIEANVKLQKQLCHNAPFYVLGPIVTDIAPGYDHITSAIGGAIAAASGADFLCYVTPAEHLGLPDKEDVKEGVIAAKIAAHAADIAKGVKGAKEKDLTMARARKALNWDEQIKLSIDPDKAFKYRVNKNISTAKTCSMCGKFCAMKIVSEYLGTSTMTC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermoanaerobacter sp. (strain X514)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.894 kDa

Sequence

MTQLEYALSGIVTKEMRIVAEYEGVDEEFILEGVKKGEIVIPSNINHKNLIPKGIGRGLSTKVNANIGTSDAYPEIEKEIEKLNVAVKAGADAVMDLSTGGDINQSRRKILENSPVPVGTVPMYQAAVESISKYGSIVAMPEEFIFEVIEEQAKDGVDFITVHCGLTFESLKKLKDNGRVMDIVSRGGSFTIAWMLHNDKENPLYKHFDRLLDIAKKYDITLSLGDGLRPGCLEDATDSAQIQELIILGELVKRARKAGVQVMVEGPGHVPIDQIEANVKLQKQLCHNAPFYVLGPIVTDIAPGYDHITSAIGGAIAAASGADFLCYVTPAEHLGLPDKEDVKEGVIAAKIAAHAADIAKGVKGAKEKDLTMARARKALNWDEQIKLSIDPDKAFKYRINKNISTAKTCSMCGKFCAMKIVSEYLGTSAMTC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.83 kDa

Sequence

MTQLEYALSGIITKEMKIVADYEGVSEEFILEEVKKGEIVIPANVNHINLVPKGIGKGLSTKVNANIGTSDAFPEIGKEIEKLKVAIDAGADAVMDLSTGGDVNKSRREIIKNSSVPVGTVPMYQAAVESISRYGSIVAMPEEFIFKVIEEQAKDGVDFITVHCGLTLESLKRLKDNKRIMNVVSRGGAFTIAWMIHNEKENPLYQYFDRLLDIAKKYDVTLSLGDGLRPGCLEDATDAAQIQELIILGELVKKAREAGVQVMVEGPGHVPIDQIEANVKLQKSLCHNAPFYVLGPVVTDIAPGYDHITAAIGGAIAAFAGADFLCYVTPAEHLGLPDIQDVKEGVIAAKIAAHAADIAKGIKKAREKDLAMAKARANLDWNEQIQLSIDPEKAEKYRVTKNKPNVETCSMCGKFCAMQIVSEYLGTPTTSC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.694 kDa

Sequence

MNYATQMEAARKGIITREMETVARKEMVDPAKLRELIAEGRVVIPANKNHASLDPCGIGQGLRTKINVNLGVSRDCCNIGMELEKARLAIELKADAIMDLSCYGRTEEFRRRLIEMSPAAVGTVPVYDAVGFYGKELKEISAEEFLGVVEKHAQDGVDFMTIHAGINRETAARFKKNPRLTNIVSRGGSLLFAWMELNGRENPFYEYFDELLEICRKYDVTISLGDACRPGSVKDATDASQIQELIVLGELTKRAWEKDVQVMIEGPGHMPLNEIIPNMLLEKKLCHGAPFYVLGPLVTDVAPGYDHITSAIGGAIAAASGADFLCYVTPAEHLRLPTLEDMKEGIIASRIAAHAADIAKGVPGARQWDDKMSEARRNLDWQKMFELALDPEKARRYRAESQPESEDTCTMCGKMCAVRNMNRVLSGAGPDG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Moorella thermoacetica (strain ATCC 39073 / JCM 9320)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.953 kDa

Sequence

MTQLEAAQVGQVTRAMEQVAAREKVRVEDLMAEVAAGRVVIPVNKNHHKLQPCGIGRGLRTKVNANLGTSTDYPDIAAELEKLQVALDAGADAVMDLSTGGDINECRRQVIARSPATVGTVPIYQATVEAQEKYGALVKMTVDDLFRVIEMQAEDGVDFITVHCGVTMEVVERLRREGRLADIVSRGGSFLTGWMLHNEQENPLYAHYDRLLEIARRYDVTLSLGDGLRPGCLADATDRAQIQELIILGELVDRAREAGVQAMVEGPGHVPLNQIQANILLEKRLCHEAPFYVLGPLVTDVAPGYDHLTAAIGGALAAAAGADFICYVTPAEHLGLPTLADVREGVIAARIAGHAADLAKGLPGAWEWDREMARARKALDWQRQIELALDPEKARQYRRARNDEGAVACSMCGDFCAMRLVGEYLGKPSETC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Desulforudis audaxviator (strain MP104C)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.335 kDa

Sequence

MNQMLAAWQGTVTPEMEQVARDEGYPVEPVLQGVAAGTIVIPANMRRKNLKAVGIGTGLRTKVNANIGTSPKQSALDDHRVKLRVALDAGADAVMDLSTGGDLDRCRREILASCPVPVGTVPIYQAAIEAKERYGAIVAMREDELFEVVERQAKDGVDFFTIHAGVTLESLDRLRKQGRLTDIVSRGGSFLTGWMLHNDRENPFYKEFDRLLEICLAYDVALSLGDGMRPGCQADATDRAQVQELLILGELVDRCREAGVQVFVEGPGHVPLDQIIMNVQLQKRLCKGAPFYVLGPLVTDVAPGYDHITAAIGGAVAAMAGADFLCYVTPAEHLGLPTVEDVREGVIATRIAGHAADLVKRVPGAREWDERMSRARKALDWEKQIELAIDPEKARRYHTERNPEKFAGCTMCGEFCAMKLVGEYLGKDYENC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.921 kDa

Sequence

MTQLQEARKGIITPEMVQAAELEGITGEELRQKIAIGEAVLPCNINHQGLRPMAVGKGLSTKVNANIGTSDAYPELAPELSKLEIAVAAGVHSIMDLSTGGDIDEIRRRIIQDSPVMVGTVPLYQVMVDTHKAGRGLVEMTDDEIFAGIEKHCRDGADFITVHCGVTLEVIQELREQGRVMDIVSRGGSFITAWMLHHQRQNPLFEQYDRLLNIALHYDVTLSLGDGLRPGCLADATDGPQIKELITLGSLVKRAQEAGVQVMVEGPGHVPLHQIETNMQLAKTLCHNAPFYVLGPLVTDVAPGYDHITSAIGGAIAASSGADFLCYVTPAEHLGLPTEEDVKEGVIAARIAAHAADLVKGIKGAWEWDLEMAKARKALDWPKQIQLSIDPEKAGRMRKAKNEDSQERCTMCGKFCAYQLISDYMGTPFKGC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Desulfotomaculum reducens (strain MI-1)

Length

432 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.958 kDa

Sequence

MTQMLAARAGEITTAMKRVAEKEGLSPEFIRQGVAEGSIVIPANINHRNLDPVGFGKGLKTKVNANIGTSTSFTDIEKELEKLKVVLEAGADAVMDLSTGGEIDQGRRRIIEESTIAVGTVPIYQSFLENRNKRGSMIAMTADDLFEVVERHCSDGVDFITVHCGITLEVLERIKKQSRITDIVSRGGSFLTGWMLHHGKENPLYEQFDRLLDICLKYDVTLSLGDGLRPGCLADATDRAQIQELIILGELVDKAREKGVQAMVEGPGHVPLDQIRANIEVQKTLCKGAPFYVLGPLVTDVAPGYDHITAAIGGTVAAAAGADFLCYVTPAEHLGLPTLEDVREGIMASRIAAHAADIVKGIPGALEWDKKMARARKALDWDEQIKLAIDPQRAAKIRQERNPDGHEACTMCGDFCAMKIVAQYLGKEPESC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)

Length

431 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.301 kDa

Sequence

MTQLKQARKNIITPGMKAIAKIEGLPPEFICQGVADGNIVIPANKLRKNLKLCGIGKGLSTKVNANIGTSTDFGTVESEVEKLKMAEMAGADTIMDLSTGPKINSVRQSILKNTCLPLGTVPVYQAAVEAKDRYGAMVKMTADDLFSAIESQAKEGVDFVTVHCGVTRQVIDTFKGQGRLTDIVSRGGTFTAGWMVFHQAENPLYEHFDHLLDICREYDVTLSLGDGLRPGCIADATDRAQVAELLVLGELVKRAREAEVQVMVEGPGHVPLNQIEANIRLQKSVCEDAPFYVLGPLVTDIAPGYDHITGAIGGAVAAAAGADFLCYVTPAEHLSLPDVTDVRNGVIASRIAAHAADIVKGVNGAAERDRQMAIARKKLDWDSQLNLSLDPEHAKLTRDRFKTKGKACSMCGDFCAMELAEKHLGVSVSRC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Dehalococcoides mccartyi (strain ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1)

Length

431 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.373 kDa

Sequence

MTQLKQARKGIVTPEMEAVAKTEGLQPEFILKGIADGNIVIPVNKLRKNLKLCGIGKGLSTKVNANIGTSTDFGSVASEVEKLKMAEMVGADTIMDLSTGPKINTIRKAILENTCLPLGTVPVYQAAVEAKDRYGAMVKMTADDLFGAIESQAREGVDFVTVHCGVTRQVIDTFKGQGRLTDIVSRGGTFTAGWMVFHGAENPLYEHFDRLLDICREYDVTLSLGDGLRPGCIADATDRAQVAELLVLGELVKRAREAEVQVMVEGPGHVPLNQIEANVRLQKSICEDAPFYVLGPLVTDIAPGYDHITGAIGGAIAAAAGADFLCYVTPAEHLSLPDVTDVRNGVIASRIAAHAADIVKGVNGAAERDRQMAIARKKLDWETQLKLSLDPEHARVTRDRFKTRGKACSMCGDFCAMELAEKHLGVSVSRC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Dehalococcoides mccartyi (strain CBDB1)

Length

431 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.279 kDa

Sequence

MTQLKQARKGIVTPEMEAVAKTEGLQPEFILKGIADGNIVIPANKLRKNLKLCGIGKGLSTKVNANIGTSTDFGSVASEVEKLKMAEMVGADTIMDLSTGPKINTIRKAILENTCLPLGTVPVYQAAVEAKDHYGAMVKMTADDLFGAIESQAKEGVDFVTVHCGVTRQVIDTFKGQGRLTDIVSRGGTFTAGWMVFHGAENPLYEHFDRLLDICREYDVTLSLGDGLRPGCIADATDRAQVAELLVLGELVKRAREAEVQVMVEGPGHVPLNQIEANVRLQKSICEDAPFYVLGPLVTDIAPGYDHITGAIGGAIAAAAGADFLCYVTPAEHLSLPDVTDVRNGVIASRIAAHAADIVKGVNGAAERDHQMAIARKKLDWETQLKLSLDPEHARVTRDRFKTRGKACSMCGDFCAMELAEKHLGVSVSRC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)

Length

430 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.481 kDa

Sequence

MDNTIIRRAREGRIDDEMRKIAEAEGVSPEKLRDRIAKGQVVYIRNVKWPSEKVVAIGKGLSTKINVNLGTSTEVVDLDSELKKVEVANKWGDTLMDLSVGGDLDAIRRAVISKSKLPVGTVPVYQAFIEAFNKRSGGAYFTIDDLFNTIERQLKDGVAFMTIHAAVTKEAAIRVLKSDRVIPVVSRGGDMIIGWMLHNDAENPYLTHWDYLLELFAQYDAVISIGDALRPGAVADAHDEFHVGELVEAARLAKRAIKAGVQVMIEGPGHVPLNDVIWTIKLEKRLTGGVPYYVLGPLPTDVAAPYDHIASAVGAALAAAAGADLLCYITPAEHLSLPTVEQVEQGAIAYRIAAHIGDVVKLGRKARRWDDEVSYYRGRLMWDEMIKRLVDPERAYKVYTQYGPPKVKGCTMCGGYCPMNMVIQQARRLK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828)

Length

430 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.526 kDa

Sequence

MKTQMNYAKEGVFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRTKVNVNLGVSNDCVDYSEEMKKVELAHKFDIEAIMDLSNYGKTSRFRDELVNVSKAMIGTVPVYDAVGFLEKDLKQIGAKDFLDVVYHHAKSGVDFMTIHAGINSRAAHIFKQSKRLTNIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQISELIELSLLTQRAWDVGVQVMIEGPGHMAINEIEVNMQLEKRLCKGAPFYVLGPLVTDIGAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKLPKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMNQILKGEDVSLA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)

Length

430 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.498 kDa

Sequence

MKTQMNYAKEGVFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRTKVNVNLGVSNDCVDYSEEMKKVELAHKFGIEAIMDLSNYGKTSRFRDELVNVSKAMIGTVPVYDAVGFLEKDLKQIGAKDFLDVVYHHAKSGVDFMTIHAGINSRATHIFKQSKRLTNIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQISELIELSLLTQRAWDVGVQVMIEGPGHMAINEIEANMQLEKRLCKGAPFYVLGPLVTDIGAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKLPKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMNQILKGEDVSLV

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

Length

430 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.525 kDa

Sequence

MKTQMNYAKEGIFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRTKVNVNLGVSNDCVDYSEEMKKVELAHKFGIEAIMDLSNYGKTSRFRDELVNVSKAMIGTVPVYDAVGFLEKDLKQINAKDFLDVVYHHAKSGVDFMTIHAGINSRAAHIFKQSKRLTNIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQISELIELSLLTQRAWDVGIQVMIEGPGHMAINEIEANMQLEKRLCKGAPFYVLGPLVTDIGAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKLPKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMNQILKGEDVSLA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)

Length

430 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.537 kDa

Sequence

MKTQMNYAKEGIFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRTKVNVNLGVSNDCVDYSEEMKKVELAHKFGIEAIMDLSNYGKTSRFRDELVNVSKAMIGTVPVYDAVGFLEKDLKQINAKDFLDVVYHHAKSGVDFMTIHAGINSRAAHIFKQSKRLTNIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQISELIELSLLTQRAWDVGIQVMIEGPGHMAINEIEANMQLEKRLCKGAPFYVLGPLVIDIGAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKLPKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMNQILKGEDVSLA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Campylobacter jejuni (strain RM1221)

Length

430 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.512 kDa

Sequence

MKTQMNYAKEGIFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRTKVNVNLGVSNDCVDYSEEMKKVELAHKFDIEAIMDLSNYGKTSRFRDELVNVSKAMIGTVPVYDAVGFLEKDLKQIGAKDFLDVVYHHAKSGVDFMTIHAGINSRAAHIFKQSKRLTNIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQISELIELSLLTQRAWDVGVQVMIEGPGHMAINEIEANMQLEKRLCKGAPFYVLGPLVTDIGAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKLPKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMNQILKGEDVSLA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)

Length

429 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.317 kDa

Sequence

MTQLLKAKEGVITREMEVVAAEERKSPEEIRQKVALGEVVIPANVNHQNLHPKGIGAGLKVKVNANLGTSENRCFYEDELKKVKVAIKAGADAIMDLSTGGNLDEIRRAIIKESSVPVGTVPLYQAAAETLNKYGDISRLDPELLFDVIEKQAADGVDFMTVHVGVTREILKVLDRFPRVTEVVSRGGSLTIAWMEKNGRENPLYEQFDRLLAICRKYDVTLSLGDGLRPGSIADATDQLQIMELMKLGELVKYAQNQGVQVMVEGPGHVPINQIEMNVKLMKRLCANAPFYVLGPLVTDIAPGYDHITAAIGGAWAAYFGADFLCYVTPAEHLGLPTVEDVEEGVIALKIAAHAADLARGNREAWNRDYEMSVARKELNWERQFELAINPERARKMRIERGSQDIKSCSMCGELCAMKIMNERGGKNA

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pyrococcus abyssi (strain GE5 / Orsay)

Length

429 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.608 kDa

Sequence

MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTEACSMCGDLCAIKIIQEMLTKKQTS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Length

429 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.775 kDa

Sequence

MTQMEEAKRGVITEEMKKIAKIEKIDPEKLRRSVAKGHTVIFRNVNHDWVVPVAVGQGVRVKVNANIGTSRDIVNVEEEIEKAKIAVKYGADTIMDLSTGGDLDFIRRKIMKAVNVPVGTVPIYQAAEEMLARGKAIIEMTEDDMWKAVEKHFKDGVDFVTIHAGVTKEVVEKLKRVNRVVGMVSRGGTFLAAWILHWGEENPFYKNYEYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTIGRLVKRAREFGVQTMVEGPGHVPIDQIPTHIRLMKIASDNAPVYVLGPIVTDIFPGYDHISAAIGGAIAALNGADFLCYVTPAEHLGLPTIEHVKEGVIATKIAAHAVNLTRFEEDFKIDYQMSLARGKLNWKEQFKIAFDKEKFIEIRKERPTKSEACSMCGDLCAIKIVREMLGHKARS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)

Length

429 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.567 kDa

Sequence

MAIIDDARKGIITDEMKKISLIEKISPEKVRKRIVEGKIMLIRNEKYPSKKIVAIGKGLTTKVNINIGTSSEVVNLDMELEKVKIANKWGDTLMDLSTGGDLDLIRREIIKHSELPVGTVPVYQVFIESFKHKSGGAYFTEDDLLNTIEKHLKDGVAFMTIHAGLTKDLAIRALKSNRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYILEMFKQYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKSALEKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAIASASGADLLCYLTPAEHLSLPTVEQVEEGAIAYRIAAHAGDIVKLGKKVRNWDDVVSYYRGKLEWEKMISSLIDPERAMKVYTQFGKPKVRACTMCGGYCPMMWAMEQVRKISD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)

Length

429 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.442 kDa

Sequence

MTLMEECRRTVPDTVRKIAEEEGVRPEKLARRVAEGRVVVPAHADRRDEVRPVGIGEGLRVKINANVGTSPEVCDPDLEVEKARAAVDHGADTVMDLSTGGDLREIRRRIMKAVDVPVGTVPVYEAAVEMTRRGRAVVDMDEDDMLRAIERHMEDGVDFMTVHCAVTLDALEDVLRRGRALGIVSRGGAIVAAWMIHHDAENPLYENFDYILELAREHDVTLSLGDAMRPGSVLDANDAAQHRELVVQGELVDRCREAGVQAMVEGPGHVPLDQIPAVVRLQKRVCDGAPFYVLGPVPTDVAPGYDHIAAAIGGAIAAYHGADFLCYVTPAEHLALPDVKDVILGVIATRIAAHAADTARGMKYARRENEEMAEARWNLDWDRQFELAIDPKKPRHYREERPPQAKELCSMCGEYCAIKILKDALEERR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

Length

428 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.34 kDa

Sequence

MTQLEEARKGVVTEEMKFIAEREGIDAEKLRRNVAKGYTVIFRNVRHDWVKPVAVGAGVRVKVNANIGTSRDIVDVKAEIEKAKVAVKYGADTIMDLSTGGDLDEIRKTIMHAVDVPVGTVPIYQAAEEMLAKGKAIIEMSEEDMWRAVEKHFKDGVDYTTIHVGVTKEVVEKMKRTKRAVGMVSRGGTFLAAWILHWGEENPFYKDYDYLLELAREYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVRRAREAGVQTMVEGPGHVPIDQIAAQVKLAKVATDNAPFYVLGPIVTDIFPGYDHITAAIGGAIAALNGADFLCYVTPAEHLGLPDVEHVRQGVIAAKIAAHAVNLTRFEADFKKDYLMALARGKLNWARQFELSMDKERFVEIRKERPTKTEACSMCGDLCAIKLINDMLAGERK

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)

Length

428 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.39 kDa

Sequence

MSIIEEARRGIITDEIKSISKLEKVSPEKVRKRIAEGKIMLLRNVKRPSKKLVPIGKGLTTKININIGTSSEVIDLDMELEKVKISNKWGDTLMDLSTGGDIDEIRRKIIDKSDLPVGTVPVYQAFIQSFKKKSGGAYFSEDELLSIVERQLKDGVAFMTIHAGLTRELAIRALKSDRVIPIVSRGGDMIAGWMIHNGKENPYRTNWKYLLELFKEYDATISLGDALRPGATADAHDEFQIGELIETARLVKDAINNGVQVMVEGPGHVPLNEVAWDVKLMKKLTGGVPYYVLGPLVIDVGAPYDHIASSIGAAIASAAGADLLCYLTPAEHLSLPNAKQVEEGAIAYRIAAHAGDIVKLGKKVRKWDDEVSYYRGKLEWDKMIEKLIDPEQAYKVYTQFGEPNVKACTMCGGYCPMMWAMEQVKKIG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Syntrophus aciditrophicus (strain SB)

Length

427 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.086 kDa

Sequence

MTQLEMAGQGRVTEEMKLCAEKEGVSPEFIRRGVEEGSIVVVRNNRHTGIAPLAIGKGLRTKVNANLGTSRDHVDLEMELEKVRICTKAGADALMDLSTGGEIRAIRQAIVNASTMAVGTVPIYAAAAEALNSRKSIMEMTADEMFQAIEENGEDGVDFITVHCGVTRESVGRIAAQGRLLGIVSRGGSITARWMDYNDAENPLYAQYDRLLEIARRYDMVLSLGDGLRPGCLADATDRGQVQELIILGELCRRARARDVQVMIEGPGHVPYPQIEANIALQKSLCEGAPFYVLGPLPTDIAPGYDHITAAIGGALAGAAGADFLCYVTPSEHLCLPNLDDVHEGIVASRIAAHIADIAKGYPGAMEKDILMAKYRSEFNWNGQIDLSVDPDRSRARLERSETAKEEGCTMCGDLCAIKLGKKKAPC

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.191 kDa

Sequence

MTQLEAAKRGEITEEMKFIAEREGIDPEKLRRSVAKGYTVIFRNVRHDWVKPVAVGNVVRVKVNANIGTSRDIVNVKAEIEKAKVAVKYGADTIMDLSTGGDLDSIRKAIMHAVDVPIGTVPIYQAAEEMLAKGKAIIEMSEDDMWNAVEKHFKDGVDYTTIHVGVTKEVVEKMKRVKRVVGMVSRGGTFLAAWILHWGEENPFYRDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVRRAREAGVQTMVEGPGHVPIDQIPAQIKLAKVATDNAPFYVLGPIVTDIFPGYDHITSAIGGAIAALNGADFLCYVTPAEHLGLPTVEHVREGVIAAKIAAHAVNLTRFEADFKKDYLMSLARGKLDWARQFELSQDREKFIEIRKERPTKTEACSMCGDLCAIKLINDMLRKG

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanococcus maripaludis (strain C6 / ATCC BAA-1332)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.129 kDa

Sequence

MTQMTDAKSGITTEEMKFVAKEEGMDVETLKNLIAKGYVVIPKNVNRNTKPVGIGDNLRTKVNVNLGTSPDFIDIACELKKVEISNKYGADAIMDLSTGGNLPEIRKEIIKNTNLPIGTVPIYEVGADAKAKYGRVIDMDEDLIFNVIERQAKEGVDFMTLHCGITKQTVSVLNNDPRKMGVVSRGGAFLTAYIMYHDKENPLYKEFDYLLELLKEHDVTLSLGDGMRPGCLQDNTDRAQIQELITLGELVDKCREKGVQVMVEGPGHVPYNNIEANMKIQKTVCKNAPFYVLGPIVTDLAPGYDHITAAIGGTLAAVSGANFLCYVTPAEHVRLMKEDDVKEGLIASKIAAQAADVAKGHELAWKLEKKMADARMKHDWKKQFEIALDSDKPRKMREEIPSKDEKACSVCGDYCALLMVEELGKR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.181 kDa

Sequence

MTQMTDAKSGIITEEMKFVANEEGMDVETLKNLIAKGYVVIPKNVNRNTKPVGIGDNLRTKVNVNLGTSPDFVDIACELKKVEISNKYGADAIMDLSTGGNLPEIRKEIIKNTNLPIGTVPIYEVGVDAKQKYGRVIDMDEDLIFNVIERQAKEGVDFMTLHCGITKQTVNALNNDPRKMGVVSRGGAFLTAYIMYHDRENPLYKEFDYLLELLKEHDVTLSLGDGMRPGCLQDNTDRAQIQELITLGELVDKCREQGVQVMVEGPGHVPYNNIEANMKIQKTVCKNAPFYVLGPIVTDLAPGYDHITAAIGGTLAAVSGANFLCYVTPAEHVRLMKEDDVKEGLIASKIAAQAADVAKGHSIAWKLEKEMADARIKHDWDRQFEIALDSDKPRKMREEIPSKDEKACSVCGDYCALLMVEELGKR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanococcus maripaludis (strain S2 / LL)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.166 kDa

Sequence

MTQMTDAKSGITTEEMKFVAKEEGMDVETLKNLIAKGYVVIPKNVNRNTKPVGIGDNLRTKVNVNLGTSPDFIDIACELKKVEISNKYGADAIMDLSTGGNLPEIRKEIIKNTNLPIGTVPIYEVGVDAKEKYGRVIDMDEDLIFNVIERQAKEGVDFMTLHCGITKQTVSALNNDPRKMGVVSRGGAFLTAYIMYHDKENPLYKEFDYLLELLKEHDVTLSLGDGMRPGCLQDNTDRAQIQELITLGELVDKCREKGVQVMVEGPGHVPYNNIEANMKIQKTLCKNAPFYVLGPIVTDLAPGYDHITAAIGGTLAAVSGANFLCYVTPAEHVRLMKEDDVKEGLIASKIAAQAADVAKGHPVAWKLEKEMADARIKHDWERQFEIALDSNKPRKMREEIPSKDEKACSVCGDYCALLMVEELGKR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.474 kDa

Sequence

MTQLTDAKSGIVTEEMKFVADEEKIDVNYLRKLIEKGYVVIPKNINRKTKPVGIGDNLRTKVNVNLGTSPDFIDISCELKKVEISNKYGADAIMDLSTGGNLPEIRSQIMKNTNLPIGTVPIYEVGVDSKEKYGRVIDMDEDLIFNVIERQAQEGVDFMTLHCGITKQSVDTLNKDPRKMGVVSRGGAFLTAYIMYHNKENPLYRDFDYLLEILKEHDVTLSLGDGMRPGCLQDNTDRAQIQELITLGELVDRCREKGVQVMVEGPGHVPYNNIQANMQIQKTICKNAPFYVLGPIVTDLAPGYDHITAAIGGTLAAVSGANFLCYVTPAEHVRLMKEEEVKEGLIASKIAAQAADVAKGNPVAWNKERQMADARIKHDWERQFEIALDSDKPKKMREEIPSKDEKACSVCGDYCALLMVEELGKR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Desulfococcus oleovorans (strain DSM 6200 / Hxd3)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

45.112 kDa

Sequence

MTQVARAKQGVVTEQMAAVAKSEGLSPEAVRDGVAAGRIVIPGNVNRRFAPVGIGSGLRTKVNANIGTSPEHHDVAEEERKLQTAVAAGAHSVMDLSTGGDLFAVRKMVLEKSPVMVGAVPIYEVAARLSAESRAFYEMTPDMLFDAIERQCAEGLDYITVHCGVTRQAAALAGADRRVTGIVSRGGSLLAAWMHDHRKENPLYEEFDRLLGIAAAYDVTLSLGDGLRPGAVADASDGAQLQELVVLGDLARRARDADVQVMIEGPGHVPIDQIGANVQMQKALCGGAPFYVLGPLTTDCAPGYDHITGAIGGAVAAAAGADFLCYVTPSEHLCLPDIDDVRVGVIAARIAAHSGDIAKKVPGALDRDMQMSACRKALDWRGMYQAAIDPCLPRQRREASHPEEESVCTMCGELCAVKTHNRMTNP

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.561 kDa

Sequence

MTQMTDAKNNIITKEMEFVAKEENIAVEKIRKWVAKGFVVIPKNIHRNTKPVGIGDNLKTKVNVNLGTSTDCIDIDMEIRKAIISEEYGADAIMDLSTGGELPEIRKQILKNTTLPVGTVPMYEIGIESKNKYGRVIDFDEDIIFNTIERQAKEGVDFMTLHCGITKHTIDTLNNDDRIMGVVSRGGAYITAYIMHHQKENPLYSQFDYLLEMLKEHDVTLSLGDGMRPGCLCDHTDRPQIQELIVLGELVDRCREAGVQVMVEGPGHVPLNNVETNMKIQKTLCKNAPFYVLGPLPTDLAMGYDHITSAIGGALAAYSGANFLCYVTPAEHVRLMNEDDVREGLIASKIAAQVADVAKGNKQAWAKEKEMAIARKNHDWEKQFELSIDSDKPKKMREELPPKEEDACSVCGEYCALLMVEEAGKR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.735 kDa

Sequence

MSIVEDARKGIITEEMKVVAAQEGVTEDFIRRGIASGQIVIPVSPYRKVKLCGIGGGLRTKVNCSVGTSTDIVDVDMEVEKVKAGERAGADTIMELSTGGDFVEIRRRCIEATTLSVGSVPLYQAFIEAARKDGAVIHMREDDLFRITEEQAKLGTNFMAIHTGVNRITLERLQRQGRHGGLCSRGGAFLTAWMLHNDKENPLYAEFDYLCEILKEHEVTLSTGNGMRAGAVHDATDRAQIQELIINAELGDRAHEMGIQVIVEGPGHVPLDQIETNVRLMKRMSGNKPFYMLGPIVTDIAPGYDDRVSAIGAAMSSMHGADFICYVTPAEHLALPNPEEVYEGVISSRIAAHVGDMIKLNKRDQDLAMGHARRDLDWEAQFNLAINPARARQIRNERASADADACTMCGDYCALKIANKVIKKLD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.477 kDa

Sequence

MTQMDDAKNGIITEEMKIVAEKEKIDIEKLRKLIAKGYVVILKNVNRDTNPVGIGQSLRTKVNANIGTSPDCVDIELEIKKAKIAEKYGADAVMDLSTGGNLEEIRKAIMDAVKIPIGTVPIYEVGKLAREKYGRVIDMNEDLMFKVIEKQAKEGVDFMTLHCGITKQSVERLKRSGRIMGVVSRGGAFLTAYILYHNEENPLYKNFDYLLDILKEHDVTISLGDGMRPGCLADNTDRAQIEELITLGELVERCREKGVQCMVEGPGHIPINYIETNIRLQKSLCKNAPFYVLGPIVTDIAPGYDHITAAIGGALAGYYGADFLCYVTPSEHLRLPTIEDVKEGVIATKIAAQAADVAKGNKLAWEKETEMAYARKNHDWEKQFELAIDKEKARKMREEIPSKEEKACSICGDYCALLMVEELGKR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanococcus maripaludis (strain C5 / ATCC BAA-1333)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.01 kDa

Sequence

MTQMTDAKSGITTEEMKFVAKEEGMDVETFKNLIAKGYVVIPKNVNRNTKPVGIGDNLRTKVNVNLGTSPDFIDIACELKKVEISNKYGADAIMDLSTGGNLPEIRKEIIKNTNLPIGTVPIYEVGADAKAKYGRVIDMDEDLIFNVIERQAKEGVDFMTLHCGITKQTVSALNNDPRKMGVVSRGGAFLTAYIMYHDKENPLYKEFDYLLELLKEHDVTLSLGDGMRPGCLQDNTDRAQIQELITLGELVDKCREKGVQVMVEGPGHVPYNNIEANMKIQKTLCKNAPFYVLGPIVTDLAPGYDHITAAIGGTLAAVSGANFLCYVTPAEHVRLMKEDDVKEGLIASKIAAQAADVAKGHSIAWKLEKEMADARMKHDWEKQFEIALDSDKPGKMREEIPSKDEKACSVCGDYCALLMVEELGKR

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)

Length

426 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.172 kDa

Sequence

MTRIEMAKKGIITEEVRQVAQEEGVFPEELSQNIAEGRVVITRNILRNIKPLGIGKGLRTKINANIGTSRDKTDIQEELEKLDIAVKYGADAVMDLSTGGPLTEMRRAILKHSSVSIGTVPIYEVAVRAIEKYGNIVKMTVDDIFNVIEEHAKDGVDFVTVHCGVTKKIVEMLKSGDRVLPIVSRGGSILADWICYHDKENPLYEYFDRLLELAKKYDLTLSLGDGLRPGCLADATDRYQLIELITIGKLKDIAISEGVQCIIEGPGHLPLNHVETNIKLQKSICKEAPFYVLGPLVTDCAMGYDHIAAAIGGALAGMYGADFLCYVTPSEHIRLPDKEDVKEGVIASRIAAHAADIAKGYAKAWQRDNKMAEARRNFDWQSQISLSFDPDKVHSMRSERPPLEDEKVCSMCGEFCAIKISRRAVE

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Length

425 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.341 kDa

Sequence

MTLIEDARKGVVTDFVKKAAEYEGIEAEKLIRLISHGYVVLPKNVRREEVQPRAIGMLTSTKVNANVGTSADYINVEEEVEKAIIAQKAGADAVMDLSSGGDLDAIRKRIMEVVEVPFGTVPIYQAARDCHRVVDMDEDDFFRVVEKHAKDGVDFMTIHAGVNWVSVERLRRSKRLLGVVSRGGAITIGWMLHNEKENPYYKDFDYLLEILKEYDVTISLGDAYRPGCIHDAGDRAKYTEFIMLGELVEKCREKGVQCMVEGPGHVPLDQIETSVRAMKSVTDNAPLYLLGPLVTDIAAGYDHIAAAIGAAIAGMAGADFICYVTPSEHLALPTVEDVREGVIAAKIAAHAIDLIKEGQRERARQRDYEMSLARKNLDWERQFELSIDPEKAREIYSRRKSESEACSMCGDLCAIKLVKEAFERD

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)

Length

425 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.862 kDa

Sequence

MSIIEDARHGIVTEEMKQVAKAEGVTEDFIRRSVAEGHIVIPVSPYRKVKICGIGEGLRTKVNASIGTSTDIVNIPEEIEKAKQAERAGADTLMELSTGGDFADIRRQIIANTTLSVGSVPLYQAFIEAVKKDGAVIHMKEDDLFRITAEQAKLGTNFMAIHTGINWETVKRLRNQGRHAGLVSRGGAFMTAWMLHNEKENPLYSEFDYLMEIMKEHEVTLSMGNGMRAGAIHDATDRAGIQELLINAELADKAHAKGIQVIVEGPGHVPIDEIATNVQLMKRVTNNKPFYMLGPIVTDIAPGYDDRVSAIGAAISSSLGADFICYVTPAEHLALPTPEEVYEGVISSRIAAHVGDMVKLKKVREADLEMGHARRDLDWERQFAVAMNPARARKIREERMPADTDGCTMCGDFCAIKIVNRYFKF

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)

Length

425 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.656 kDa

Sequence

MTIVEDAKKGLITEEMKVVAKSEGVTEDFIRRGIAGGHIVIPMTPYRKVKLCGIGSGLRTKVNASIGTSSDIVNVEEELEKARQAELAGADSLMELSTGGDFLDIRRRVCEQSNLSVGSVPLYQAFIEAARNKGGVVFMDEDDLFKITEQQAKLGTNFMAIHTGINYETVKRLKNQGRHGGLVSRGGAFMTAWMLHNEMENPLYRRFDYLVEILKEHEVTLSFGNGMRAGACHDATDRAAIQELLINAELADQAHNAGVQCILEGPGHIPLDEIKTNVQLEKRVTNNKPFYMLGPLVTDIAPGYDDRVAAIGASVSSAAGADFICYVTPAEHLALPTPEEVYEGVMSSRIAAHVGDMVKLPKTREADLEMGHARRDLDWERQYAVSINAEKARCIRNSRMPADSDACTMCGDFCAIKIVQKTFNF

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.644 kDa

Sequence

MNYKTQREAARKGIETPEMKKAAEKEGVELKYLQEGLAAGKIALPANRNHLSLQAAAIGAGLKTKINVNLGISRDCSNMEEEMRKVEKALEMQADAIMDLSCHGKTQEFRKALLAISPAMIGTVPVYDAMGFLEKELSEITVAEFLQVVETHARDGVDFMTIHAGIRRTTLERLRKTPRLTSIVSRGGALLCTWMERNKAENPFYQYFDEVLDICREYDVTLSLGDACRPGSINDASDACQLEELITLGDLTLRAWEKDVQVIIEGPGHMPLNEIEANVLLQKKLCHSAPFYVLGPLVSDIAPGYDHITSAIGGAIAAAAGADFLCYVTPAEHLRLPSLEDMAEGIIAARIAAHAADIAKGLPGASEWDWQMSKARAELDWESMFKLAIDPEKARRYRAESSPELEDSCTMCGQSCALRNMKNL

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.155 kDa

Sequence

MTQMEMARKGVVSDEMKKVAEYEGVDVEIVRQKLAEGRAVLPKNKLHRIERPMIVGEGFSVKVNANIGTSQGFSSLEEEKEKARVAIEYGADSLMVLSTWGDLREIRRAIVEMSPVPVGSVPIYDSAVRSYQMKKNVVDFSEKDFFDMVIAHAEDGIDFMTIHVGVTRRVLDRIKSSRRVLKIVSRGGAIIAGWMIKNNKENPFYEHFDELLDIAKDYDITLSLGDGMRPGAVVDASDAQQFEELFVMGELVERAREKGVQVMLEGPGHVPLNEVEMNVRLMKKIGKGAPIFLLGPLPTDRAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPDVEDVREGVIASKIAAIVADVARGNKKAWELEKKMALARKNFDWETMFSLSLGKDVAKKKYEERPYPDKGCSMCGPFCAIKIAEEFS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.358 kDa

Sequence

MTQMEMARKGIVSEEMKKVAEYEGVDVEEVRQKIAEGRAVLPKNKLHRVSKPMIVGEGFSVKVNANIGTSQGFSSIEEEKEKARVAIEYGADSLMVLSTWGDLREIRRTIVEMSPVPVGSVPIYDSAVKSYQMKKNVVDFSEKDFFDMVIAHAEDGIDFMTIHVGVTRRVLERVKNSKRILKIVSRGGAIIAGWMIKNNRENPFYEHFDELLDIAKEYDITLSLGDGMRPGAVVDASDSQQFEELFVMGELVERAREKEVQVMLEGPGHVPLNEVEMNVKLMKKVGKGVPIFLLGPLPTDRAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPDVEDVREGVIASKIAAVVADVARGNRKAWELEKRMALARKNFDWETMFDLSLGRDIAKKKYEERPYPDKGCSMCGPFCAIKIAEEFS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.155 kDa

Sequence

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Thermotoga sp. (strain RQ2)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.155 kDa

Sequence

MTQMEMARKGVVSDEMKKVAEYEGVDVEIVRQKLAEGRAVLPKNKLHRIERPMIVGEGFSVKVNANIGTSQGFSSLEEEKEKARVAIEYGADSLMVLSTWGDLREIRRAIVEMSPVPVGSVPIYDSAVRSYQMKKNVVDFSEKDFFDMVIAHAEDGIDFMTIHVGVTRRVLDRIKSSRRVLKIVSRGGAIIAGWMIKNNRENPFYEHFDELLDIAKDYDITLSLGDGMRPGAVVDASDAQQFEELFVMGELVEKAREKGVQVMLEGPGHVPLNEVEMNVRLMKKIGKGAPIFLLGPLPTDRAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPDVEDVREGVIASKIAAIVADVARGNKKAWELEKKMALARKNFDWETMFSLSLGKDVAKKKYEERPYPDKGCSMCGPFCAIKIAEEFS

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

47.521 kDa

Sequence

MTQMEIAQKGTSSEEMKRVAEYEEMNLEVIRQKLAYGKAVLPKNKLHKIEKPMIVGEGFTVKVNANIGTSQAFFSLEEEKEKARVAIEYGADSLMVLSTWGDLKEIRKAIIDLSAVPVGSVPIYDSAMKSYQLKKNVVDFSEKDFLNMVISHAEDGIDFMTIHAGITKKVLEHVKNSGRILKVVSRGGAIIAGWMIKNNKENPFYEYFDELLDIAKDYDITLSLGDGMRPGTVLDASDVQQFEELFVMRELVEKAREKGVQVMLEGPGHIPLNEVELNVKLMKKIGEDAPIFLLGPLPTDRAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPTIEDVREGVIASKIAAAIADLARGNRKAWWLEKQMALSRKNFNWEEMFKLSLGKDLARKKYKERPYLHEGCSMCGPFCAIKIVEEFF

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.944 kDa

Sequence

MSLIEDARRGVVTEEMRIVAAAEGVTEDFVRRGVAEGHIVIPVSPYRRVKICGIGEGLRTKVNASIGTSTDMVDVDMEVEKVRQAERAGADTLMELSTGGDFLEIRRRVVEATTLSVGSVPLYQAFIEAARKRGAVVHMEPDDLFRITAEQAKLGTNFMAIHTGINYETMKRLQNQGRHGGLVSRGGAFMTAWMLHNEKENPLYSEFDYLLEILKEHEVTLSFGNGMRAGAVHDATDRAQVQELLINAELADKAHEQGVQTIIEGPGHIPVDEIQTNVVLQKRVTNRRPFYMLGPLVTDIAPGYDDRVAAIGAALSSSYGADFICYVTPAEHLALPTPEEVYEGVMSSRIAAHVGDMIKLKKRDADLEMGHARRDLDWERQFAVAMNPERARAIRDERMPADTDGCTMCGDYCALKIVGRHFNF

Protein

Phosphomethylpyrimidine synthase: thiC

Gene

thiC

Protein

Phosphomethylpyrimidine synthase

Organism

Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)

Length

424 amino acids

Function

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

Similarity

Belongs to the ThiC family.

Mass

46.236 kDa

Sequence

MSLIKDAQRGLVTEEMKLVAAQEGVTEEFVRKGVAGGHIVIPVSPYRKVKICGIGEGLRTKVNASIGTSSDISDVSVEIEKVRQAELAGADTLMELSTGGDLADIRRQVIAATSLSVGSVPLYQAFIEAAHKKGAVVDMEADDLFRITAEQAKAGTNFMAIHTGINYETMKRLQNQGRHAGLVSRGGAFMTAWMLHNEKENPLYAEFDYLLEIMKEHEVTLSMGNGMRAGAVHDSTDRAAIQELLINAELADKAFNEGVQTIVEGPGHVPIDEIQANVILQKRVTNRKPFYMLGPLVTDIAPGYDDRVAMVGAALSSSYGADFICYVTPAEHLALPTPEEVFEGVISSRIAAHIGDMVKLNKRDDDLEMGHARKALDWDRQYAVAINPKRAKEIRDSRMPADTDGCTMCGDYCAIKIVAKHFNF

Protein

Phosphomethylpyrimidine synthase: thiC