Protein
Methanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase
Organism
Rhodococcus erythropolis
Function
Catalyzes the oxidation of methanol to yield formaldehyde. While the in vivo electron acceptor is not known, N,N-dimethyl-4-nitrosoaniline (NDMA) can serve this function in vitro and is reduced to 4-(hydroxylamino)-N,N-dimethylaniline.
Similarity
Belongs to the iron-containing alcohol dehydrogenase family.
Sequence
AIELNQIWDFPIKEFHPFPRALMGVGAHDIIGVEAKNLGFKRTLLMTTGLRGSGIIEELVGKIEYQGVEVVLYDKVESNPKDYNVMEAAALYQKEKCDSIISIGGGSSHDAAKGARVVIAHDGRNINEFEGFAKSTNKENPPHIAVSTTAGTGSETSWAYVITDTSDMNNPHKWVGFDEATIVTLAIDDPLLYYTCPQHFTAYCGFDVLAHGSEPFVSRLDFAPSLGNAIYSVELVAKNLREAVFEPRNLKAREGMMNAQYIAGQAFNSGGLGIVHSISHAVSAFFDSHHGLNNAIALPRVWEYNLPSRYERYAQLAGALGVDTRNLTTVQAADAAVEAAIRLAKDVGIPDNFGQVRTDSYAKNQMNTKKYEGRGDVIKGDEKTVRAISEHIQDDWCTPGNPREVTVESMIPVVDHAINKSYF