tgs2

Gene

tgs2

Protein

Probable diacyglycerol O-acyltransferase tgs2

Organism

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Length

454 amino acids

Function

Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity).

Similarity

Belongs to the long-chain O-acyltransferase family.

Mass

49.304 kDa

Sequence

MDLMMPNDSMFLFIESREHPMHVGGLSLFEPPQGAGPEFVREFTERLVANDEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSALPSPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHALIDGVSAMKLAQRTLSADPDDAEVRAIWNLPPRPRTRPPSDGSSLLDALFKMAGSVVGLAPSTLKLARAALLEQQLTLPFAAPHSMFNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYYLIERNALPDRPLIAMVPVSLRSKEDADAGGNLVGSVLCNLATHVDDPAQRIQTISASMDGNKKVLSELPQLQVLALSALNMAPLTLAGVPGFLSAVPPPFNIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNNAGNLDFGLVGCRRSVPHLQRLLAHLESSLKDLEQAVGI

Protein

Probable diacyglycerol O-acyltransferase tgs2: tgs2

Gene

tgs2

Protein

Probable diacyglycerol O-acyltransferase tgs2

Organism

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Length

454 amino acids

Function

Upon expression in E.coli functions as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions as a wax synthase, incorporating palmityl alcohol into wax esters in the presence of palmitoyl-CoA.

Similarity

Belongs to the long-chain O-acyltransferase family.

Mass

49.304 kDa

Sequence

Protein

Probable diacyglycerol O-acyltransferase tgs2: tgs2