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tfe

Gene
tfe
Protein
Transcription factor E
Organism
Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length
211 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
24.545 kDa
Sequence
MTVITEEQLGNPAIYQYLLKLVGEEGLELLRRWSDVSYARRWVEEKLSSEDLKAADKARFLAESRRSDEDLVEAERSDEEIAELTGINLNSVRHTLYNLYEHRLAEYRRIKNNETGWLTYLWLMRMDHMNMVLRNEMEVAAGKLAGRLRYDEANDFYQCKNCGITTTFNNAMTTNFSCPQCGTMLVHFDDELIITALKKRLAKMQTALDNA

Gene
tfe
Protein
Transcription factor E
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
195 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
22.885 kDa
Sequence
MGRDKKNTALLDIARDIGGDEAVEVVKALEKKGEATDEELAELTGVRVNTVRKILYALYDAKLATFRRVRDDETGWYYYYWRIDTKRLPEVIRTRKLQELEKLKQMLQEETSETYYHCGTPGHPKLTFDEAFEYGFQCPICGEILYEYDNSKIIEELKKRIEELEIELGLRSPPKEEKPKKATRRKKSRSGKKKK

Gene
tfe
Protein
Transcription factor E
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Length
191 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
22.469 kDa
Sequence
MSKRNKELLEIGRDIGGDEAVEIIKALEKKGEATDEELAEITGIRVNTVRKILYALYDAKLADFRRVKDDETGWYYYYWHIETKRLPEIIRARKMQELEKLKKMLQEETSEVYYHCGNPDHPKLTFDEAFEYGFVCPICGEILHQYDNSAVIEELKKRIEELEIELGLRAPPKKEKKGKKSKKRSKKSKKK

Gene
tfe
Protein
Transcription factor E
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Length
190 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
22.457 kDa
Sequence
MSRKNKALLEIAKDIGGDEAVEIVKALEKKGEATDEELAEITGIRVNTVRKILYALYDEKLADFKRIKDEETGWYYYYWHLETKRLPEIIRARKLRELERLKKMLQEETSEVYYHCGNPEHPKLTFDEAFEYGFTCPICGEILQEYDNSAVIEELKKRIEELEIELGLRPSPKKEKKKTRAKAKRKTRKK

Gene
tfe
Protein
Transcription factor E
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Length
189 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.841 kDa
Sequence
MKGKGRNRAVKSLEIYVRKLAQANGIKPEMAAHIFHLIYEETPNGGISDDDLESLTGYKQSDIRRILRLLGDKRIIVSRKGRHPRKEATRYFWRIDSDTINVSLLTLKKKVLEKLVVKEAHDSGNSYYTCPRCGSKYSFDEAFTLDFTCPRCGEVLEEADSREGLERLRRTIDALREEIARDESRIYRS

Gene
tfe
Protein
Transcription factor E
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
188 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
22.605 kDa
Sequence
MYAELGEEDLEVLRDVTLSLLDSEKGVDPEVAKRTVDVILKREAIDEEIAEELGVDPREVRKVLYKLHERGVVTFRKERREEYRYPVYSWRLNLREVLRRCLEERRRELEEVERALSNDMSHPMFHCGNDDCPRMSFEEAMEHEFRCPKCGEVLEEVDLTEERRELERLAEELKVEIRRLEELRERLG

Gene
tfe
Protein
Transcription factor E
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
185 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
22.05 kDa
Sequence
MAKRKNKELLEIAQEIGGEEAVEVVKALEKMKEATDEELAEATGIRVNTVRRILYMLNDEGLADFKRIRDPETGWYYYYWRLETKKLPEIIRSRKMAELKKLKEMLEEETSEIYYWCGTEGHPKLTFDEAMEYEFQCPICGKMLMQYDNTHIIEELKRRIEELEIELGLKKKPRKTSKKKKSRSE

Gene
tfe
Protein
Transcription factor E
Organism
Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Length
183 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.004 kDa
Sequence
MQPYIELVRRYVYRRILIEFGDDELGKLAVAIFNTLLSRGEAMTDDKLTSIVGYNAIDVRRILQALYNMRLASVVEEFNEAAGRIEQSWSIKDEDIRRFLINLIGGVLDKVGVLMQQLTNTPIYICPKCFKRYSEDDALMYDYKCPLDRTPLEYINPADYLTVLGAVEARLKKMMESVSKGSV

Gene
tfe
Protein
Transcription factor E
Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Length
179 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.533 kDa
Sequence
MAKKKVKYTFDYDSKFLNEHNVKKLAYELTHDSDTSNKILDCLFTAEVTDEQIAEATGIKLNFVRKILYKFYDVGMANYTRKKDPETQWFTYYWRFDSRKAAQILEKQYNHHNQEIKESIEYEENNMFFVCPNGCRYPFDEATEFQFICPRCNEKLEFKDNSDLIHDLKKLESAYKINE

Gene
tfe
Protein
Transcription factor E
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.164 kDa
Sequence
MIDEQVLQELIHEVITEEEEEEAIPVLECLMKGKVTDEEISEKTQLKLNIVRRILYRLYDAGVASYKRSKDPETQWYTYTWKFEPEKVTEMIKRKHSEIVRKLREALEFEENNMFFVCVNGHYRFTFDEATEENFTCPECGSKMEFMDNSEIIQEIKDELSLYENNGFDSIKTTTINS

Gene
tfe
Protein
Transcription factor E
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.173 kDa
Sequence
MVNAEDLFINLAKSLLGDDVIDVLRILLDKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKTRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTDKIKSFLEQKIRQIEEEIDKETKLGANKNH

Gene
tfe
Protein
Transcription factor E
Organism
Sulfolobus islandicus (strain M.16.27)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.146 kDa
Sequence
MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLGANKSH

Gene
tfe
Protein
Transcription factor E
Organism
Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.146 kDa
Sequence
MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLGANKSH

Gene
tfe
Protein
Transcription factor E
Organism
Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.146 kDa
Sequence
MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLGANKSH

Gene
tfe
Protein
Transcription factor E
Organism
Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.146 kDa
Sequence
MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLGANKSH

Gene
tfe
Protein
Transcription factor E
Organism
Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.146 kDa
Sequence
MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLGANKSH

Gene
tfe
Protein
Transcription factor E
Organism
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
21.416 kDa
Sequence
MSSRAEELILSLAKDLVGEDATELLKFLLRKRIEMTDDDIAKELNVKVNEIRKKLYLLSEQGFITYRKTRDKETGLFIYYWKVNIDQINELLLNRKRLVLEKLKARYEQEKDSLYYYCPQDNIQYNFDEALENEFKCPKCGSPLEYYDSEKTKKFLEYKIKQIENEIERETRHGSNSR

Gene
tfe
Protein
Transcription factor E
Organism
Thermofilum pendens (strain DSM 2475 / Hrk 5)
Length
178 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.575 kDa
Sequence
MNAHEALAEIAGKMFGDNAKKVMMVLASNVEVSDEDLAKDLKMDPPELRKLLNDLFEARLVKYRRARDENIGWYKYYWRITDEPIQQILSDRKRLTLSILEKVLSLEENSETYVCPKCGTRYTVDEAENNNYTCEVCGEVLEPFDNTHRVEKLKRAIELLGNWDPSPKQQASRAIPHA

Gene
tfe
Protein
Transcription factor E
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
177 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.373 kDa
Sequence
MKAETTTGVEELLNELVGRAAGEVGLILFSLGIEGEFTDDQLSLELGIEINEIRKALFALYEIGLADYVRRRDDETGWMEYYWRINYDKALDVLKRELEKTAKKLREKIEAETSTIYYICPNMCVKVSYNDAMELNFTCPRCGAMLDYLDCSKAIEKIEEEVRRIEEILESLDKNSG

Gene
tfe
Protein
Transcription factor E
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Length
176 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.735 kDa
Sequence
MAFEELLEDPVIQKYLHELVGPKGMPVAAAPPDGEVTDEELAEELGLELNDVRRALFILYENDLATYRRLRDEDSGWLTYLWTFQYEKIPEQLQEEMHRLLDGLEERREYERENEFYLCEHCGIRFEFGEAMEFGFECPECGNQVETMENTRLVTAMENRLEELRDELNADVDVEA

Gene
tfe
Protein
Transcription factor E
Organism
Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Length
176 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.92 kDa
Sequence
MTGNIDQLMKDMARDLLGEDVIDVLSFLLDNKTELTDEEMANKLNVKVNEVRKKLYALAEHGLVSYRRTRDKETGWYVYYWKANVDQINELLLSRKREILNKLKARLEYETNNEFYICPEDKTKYTFEEAFENEFKCPKCGVQLVYYDSAKMREFLERKIKEIEEEIARETKVGSS

Gene
tfe
Protein
Transcription factor E
Organism
Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)
Length
176 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.365 kDa
Sequence
MAFDELLNDPVIQKYLHELVGPTGMPVAAAPPDGEVTDEELAEELGLELNDVRRALFILYENDLATYRRVRDEDSGWLTYLWTFHYENIPENLQSEMYRLLDALEERLEYERSHEFYLSEPAGIRFEFSEAMELGFQCPETGAPLEPIENQEMINAMERRIDSLQSELNVGVTQTV

Gene
tfe
Protein
Transcription factor E
Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Length
175 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.847 kDa
Sequence
MLDNPLIQQVLFEVMEEDVVGFDVLNVLIDSNEVTDDEISRQLEVKLNNIRRILYKLYEARLVDYNREKDEETNWYTYTWKPSLEKLPALVVKKMKNILDELKKQLSTEENGMFFYCMGCELKFTFEDAMDMGFRCPQCGGVLHEYDNKKDMATIKEQIAYIEDEFNQNPLFFKY

Gene
tfe
Protein
Transcription factor E
Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)
Length
175 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.503 kDa
Sequence
MAFEDLLNDPVIQKYLHELVGPTGMPVAAAPPDGEVTDEELAEELGLELNDVRRALFILYENDLASYRRLRDEDSGWLTYLWTFQYENIPEQLEEEMHRLLEALENRRQYESENEFYLCGECQLRFEFDEAMEFGFECPECGGRLESMENDRLVNAMEQHIEALRDELHVETAEA

Gene
tfe
Protein
Transcription factor E
Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Length
175 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.774 kDa
Sequence
MLENPLIQQVLFEIMDEDVVGFDVLSVLINTNEVTDDEISRQLDVKLNNIRRILYKLYEARLVDYNREKDEETNWYTYTWKPSLEKVPALVAKKMKNVLNGLKEQLEMEETNMFFFCSDCEIKFTFEDAMDSGFRCPQCGGMMYEYDNKKDISLLKEQINYLEDEFTKNPLFSAY

Gene
tfe
Protein
Transcription factor E
Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Length
175 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.841 kDa
Sequence
MLENPLIQQVLFEIMDEDVVGFDVLSVLINTNEVTDDEISRQLDVKLNNIRRILYKLYEARLVDYNREKDEETNWYTYTWKPSLEKVPALVAKKMKNVLKDLKEQLELEETNMFFFCSDCEIKFTFEDAMDSGFRCPQCGGMMYEYDNKKDISILKEQINYLEDEFNKNPLFSAY

Gene
tfe
Protein
Transcription factor E
Organism
Methanococcus maripaludis (strain S2 / LL)
Length
175 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.869 kDa
Sequence
MLENPLIQQVLFEIMDEDVVGFDVLSVLINTNEVTDDEISRQLDVKLNNIRRILYKLYEARLVDYNREKDEETNWYTYTWKPSLEKVPALVAKKMKNVLNGLKEQLNVEENNMFFFCSDCEIKFTFEDAMDSGFRCPQCGEMMYEYDNKKDISLLKEQIKYLEDEFNKNPLFSTY

Gene
tfe
Protein
Transcription factor E
Organism
Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)
Length
175 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.923 kDa
Sequence
MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLWGK

Gene
tfe
Protein
Transcription factor E
Organism
Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.176 kDa
Sequence
MSSEIEKLFTFVEKLVDSDARKVFEALYEAGEELSEADIATKTGLKLNVVRRALNSMAEKGLVVYRRQKHPQKNKLVFYWRINYEGLPSIIESRKRAAHEKLRTLLEKEESVHYYVCPRDGTRYTFEEALDHEFICPRCGSMLVLDEERELRIQILKQYIKMLEDELGGAKAS

Gene
tfe
Protein
Transcription factor E
Organism
Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.697 kDa
Sequence
MAKKDPLEELLEFVRSVAGEDGVRVFKELMRYEDISEEQLTETLGMKPNDVRRALYKLERYGLVRNYKIRNENDGTYIYYWYVDRETLNRNLLKIKKSVLEKLKRRLESEEDQYFYCPACGLQFSYEEAMGYDFTCPRCGEPLELAESNPRKKLLEKIVKRLEEEIKHEESVL

Gene
tfe
Protein
Transcription factor E
Organism
Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.541 kDa
Sequence
MLNNPIIQQVLLEILGDDINGFNVLEALTELTEVTDDEISRQLDLKLNTVRKLLYKLYDARLVDYNREKDEETNWYSYTWRATFTKLPGVVKKRMEQLLIDLKEQLEVEENTLFFYCPRCEFKYSFDEAIDYGFRCSQCNGVLKEYNNKNDILMIKNQIKIIEEELALNPLFS

Gene
tfe
Protein
Transcription factor E
Organism
Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.138 kDa
Sequence
MDPVEEVLNNPATRAYIHRLIGDEGINLLERFPKDGEHSDEDLAASTGINLNSVRHTLYTLYEKRLAEYHRIKNNETGWLTYLWQLRIDLLYDAIREDMETVLSKLERRARFEEENDFYICKDCHDIYTFTVAMGGNFTCPNCGQPLSHFENETLAKALRARIEIMKKTLGHA

Gene
tfe
Protein
Transcription factor E
Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.515 kDa
Sequence
MASHEEILADKAIFAYLHRMIGDEGIELIRRFPTDKEYSDEELAEVTKINLNSVRNTLYTLYEHRLAKYRRIKNNETGWLTYLWELELDNMYDSVSKDLEIILEKLRKRYKYESENAFYNCPNCGNTITFSDAMDSQFVCQECENKMVHFDNDLLVNALQKRIARIEENLGHV

Gene
tfe
Protein
Transcription factor E
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.667 kDa
Sequence
MLNDPLVQEVLFNIFEGDEKGFEVIDVLLEKGETTEEEIAKELGVKLNVVRKLLYKLYDARLVDYKRWKDEDTNWYSYTWLPTLEKLPYVVKKKINELIKDLEKKLEFEKNNMFFFCPNCNVRFTFEEAMDYGFSCPGCGNMLQEFDNSELIKDLEEQIKFLKEELKNNPFLK

Gene
tfe
Protein
Transcription factor E
Organism
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.402 kDa
Sequence
MVSVTELLDDPAINAYILRMIGEEGIELLRRFPEGGEHSDEELAEMTGVNLNTVRHTLYTLYERRLAEYRRLKNTETGWLTYLWHLRLDRVHDVLEEQVRDALEHLDARLAYEEKNDFYMCRNCSVVYTFTDAANWNFECPNCEEMLEHFDNELIAVALRKRIDRIKESLGSA

Gene
tfe
Protein
Transcription factor E
Organism
Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)
Length
173 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.33 kDa
Sequence
MIDDPLVKSLLTNVVEDESNLPIVQALIDGVETDEAIAEKTEIKLNIVRKILYKLYDMGLATYKRSKDPETQWFTYSWKFEEQEVINHIKSDSEEYLKMLNKELEKEEDTMYFVCPQGHIRLDFETATEYDFICPECGEELEFFDNTNLIKQIKDDIKTVESNYKSFTKKVDA

Gene
tfe
Protein
Transcription factor E
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
172 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.884 kDa
Sequence
MAFEDLLDDPVVQKYLHELVGPKGMPVAAAPPDGEVTDEELAERLGLELNDVRRALFILYENDLATYRRVRDEDSGWLTYLWTFQYENVPGNLREEMDRLLEALVDRREYELENEFYLCEVCSIRFEFGEAMDLGFECPECGSAVEAMENTDLVDAMDDRIERLRSELAVEA

Gene
tfe
Protein
Transcription factor E
Organism
Cenarchaeum symbiosum (strain A)
Length
171 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.024 kDa
Sequence
MIDKYEDPFIRIAVMIGGDEYLKVARSLLKAEDATDEEIASSTGLRINMVRKVLYDLFGKSLISGVRVKDERKGWFVYRWRSRREEVESFIENQKKKIMGRLQQRLDYENSSEFYHCGNDDCQRITFEGALEEMFKCPSCGKVLNLKKNDKAKKAFGKKIDEIKKDLQQTF

Gene
tfe
Protein
Transcription factor E
Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Length
171 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.357 kDa
Sequence
MLNLAKELVGDEALGLLKYLIGKKSEITDEEIAKELNTKPNEVRKYLYLLSDHGLVTYRKTKDKDSNLYIYYWKVNVNQINEILLSRKRLILEKLRNRYEQEKDGLFYFCPQDNIKYSFDDAIENEFKCLKCGTSLSQYDSEKARSFLEQKIKQIEEEINKEIRRESSKSY

Gene
tfe
Protein
Transcription factor E
Organism
Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)
Length
171 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.184 kDa
Sequence
MSALDNKAVRGYIQKLVGDEGMAVVEKMIEKVPDQEVTDEQVAQISGINLNLVRKTLYILYENHLAMYRRERDKDSGWLTYLWKLDLDNSVHMLRNEARKLIKKLERRLEFESNEFYICQEEAPHRILFDYAMETNFVCPVDETPLMHYDNTAEKQALRNRIDDLKKSLAQ

Gene
tfe
Protein
Transcription factor E
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
170 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.858 kDa
Sequence
MKDVYLYIVEKSVAWEFDSPEYGRLARKVAEMLYERKEDLTDDRIAILLNISTAETRRILQYLMRLNLVGVKKRTTEDYRIEYTWYVDDEIIKQAIGGRARTAREKISMLIRALTEGSYYICPNCHMRYSLDEAVNKGGVCPVCGAELEYVESLEEINKLTKVLQKLEKL

Gene
tfe
Protein
Transcription factor E
Organism
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length
170 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.04 kDa
Sequence
MKDAYLYVVEKSVAWEFDSPEYGRLARKIVELLYERKEDLTDDRIAILLNISTAETRRILQYLMKLNLIGVRKKTTEDYRIEYAWYVDDEIIRQAISSRARVVREKLSMLIRSLTEGAYYICPSCFIRYSLDEAVNWGGTCPICGTQLEYVENVEEINKLTKIFEKLEKL

Gene
tfe
Protein
Transcription factor E
Organism
Pyrobaculum calidifontis (strain JCM 11548 / VA1)
Length
170 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.042 kDa
Sequence
MKDVYLYIVEKSVALEFDSAEYGRLARKTVELLYDRKEELTDDRIAILLNISTAETRRILQYLMKQNLVGVKKRSTEDYRIEYTWYVNDEVISQAVKYRAKVVREKISLMIKALTEEAFYVCPNCFMRYPVEEVMERGGVCPICGSHLEYVENVEEINKLTKVFEKLDKI

Gene
tfe
Protein
Transcription factor E
Organism
Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)
Length
170 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
20.037 kDa
Sequence
MKEAYLYIVEKSVAWEFDSPEYGRLARKVVELLYERKEDLSDDRVAIFLNISTAETRRILQYLMKQNMVGVKKRTTEDYRIEYTWYVDDEIIRQAIKNRAKVAKEKISSLIRSLTEGAYYICPTCHMRYTLDEAINYGGVCPVCGTQLEYVENTEEINKLTKVYEEVDKI

Gene
tfe
Protein
Transcription factor E
Organism
Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta)
Length
170 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.771 kDa
Sequence
MKEAYLYIVEKSVAWEFDSPEYGRLARKVVELLYDRKEDLTDDRVAILLNISTAETRRILQYLMKLGLVGVKKRTTEDYRIEYTWYVDDDVIRQAIKNRAKVAKEKISSLIKSLTEGAYYVCPTCHMRYTLDQAVNYGGVCPVCGTQLEYVENVEEIDKLTKAYESIDKI

Gene
tfe
Protein
Transcription factor E
Organism
Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)
Length
167 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.306 kDa
Sequence
MVAVENPIHRAYLLKIVGEEGLRIVEAMPEEEVTDEHLAEITGISLNTVRKSLYLLYEHRLAIYRRKRDPESGWLTYLWKICPESLDSALEAEVRKLINKLNARLRYEKDHVFYACVNGCARFVFEEASENNFTCPFCQGSLEYMENSTIVEVIEERIKELSAALCS

Gene
tfe
Protein
Transcription factor E
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
167 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.514 kDa
Sequence
MNTLVDLNDKVIRGYLISLVGEEGLRMIEEMPEGEVTDEEIAAKTGVLLNTVRRTLFILYENKFAICRRERDSNSGWLTYLWHLDFSDVEHQLMREKKKLLRNLKTRLEFEENNVFYVCPQGCVRLLFDEATETEFLCPMCGEDLVYYDNSRFVSALKKRVDALSSV

Gene
tfe
Protein
Transcription factor E
Organism
Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
Length
165 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.042 kDa
Sequence
MTDSNDPVVRGYLLQLIGEEGIEMIENMPEGEVTDEQIAEASGVMLNIVRRTLFIMNENNLAVCRRERDSSSGWLTYLWQLDLSDIESHLVKEKKRITKNLEIRYNFEVDSVFYTCPEGCVRFEFKEASKCEFMCPACGEDMMFEDNSVMVKKLRDRLDALEASS

Gene
tfe
Protein
Transcription factor E
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length
164 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.238 kDa
Sequence
MVDLNDKVIRGYLLSLVGEDGLQMIEKMPEGEVTDEEIAAKTEVLLNTVRRTLFILNENKFAICRRERDSNSGWLTYLWRLDFSDIEHQLMKEKKKLLRNLKTRLEFEENNVFYMCPQGCVRLLFDEATETEFLCPMCGEDLVFYDNSHFIDVLRKRVDALSSA

Gene
tfe
Protein
Transcription factor E
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
164 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
19.145 kDa
Sequence
MVDLNDKVIRGYLRSLVGDDGLKMIEQMPEGNVTDEEIAAKTGVLLNTVRRTLFILYENKFAIVVRERDSNSGWLTYLWHLDFSDIEHQLMREKKRLLRNLKTRLEFEENHVFYVCPQGCVRLLFDEATETEFLCPMCGEDLVYYDNSRFVGVLKKRVEALSSA

Gene
tfe
Protein
Transcription factor E
Organism
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)
Length
156 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
18.045 kDa
Sequence
MYGEKAKKVLLHIIRSGGIVAEETLGKDIGMKSNEARKILQQLADEAILRYKTGRVGDKTLHLWILNIDQIEGILIARLKKTREKLLIRLNYEKNNTFLKCPLCGRRYTFDEAFENDFLCPYDGEQLIEYDNSEEIRILEEKIKEITDELSRIGAA

Gene
tfe
Protein
Transcription factor E
Organism
Nanoarchaeum equitans (strain Kin4-M)
Length
139 amino acids
Function
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
Similarity
Belongs to the TFE family.
Mass
16.316 kDa
Sequence
MPTSKQIINKKQDEVSDIYGKEMIRVIRSLLKHKIIDTESLSKKTGYSINTVRRALYTLQKMGIVRYINKEDKTLWQLLETDYEKILDTLLEPYKKEEKAETGELLFICPKCGRKYTLDEAEMYEFRCPEDGTLLVANQ