tfdFII

Maleylacetate reductase 2

359 amino acids

Plays a major role in the degradation of chloroaromatic compounds by channeling maleylacetate and some of its substituted derivatives into the 3-oxoadipate pathway. This enzyme converts maleylacetate and 2-chloromaleylacetate with similar efficiencies. NADH is preferred to NADPH as the cosubstrate.

Belongs to the iron-containing alcohol dehydrogenase family.

37.504 kDa

MTGDLNEFVAHFWPVRVVFGAGSTERIPAEVKRLGARRALVLCTPDQRDLAQRVLGDLGDLGAGFHDGAVMHVPEASVTRAAQAARDADADLLVAVGGGSTIGLAKALALHHGMRFVALPTTYAGSEMTPIWGLTADGAKRTGRDPRVLPSTVLYDPHHLTSLPPEVTGPSGMNAIAHAVESMYAPDRNPITMLLAEESIRAMAQGLPVAVDSPGDLDARTRTLYAAWLAGTVLGMVSMGLHHKLCHVLGGRFNLPHAPMHAVLLPHVAAFNEVAAPAELGRVAAALGAPGPGGAGAALHALLRFTCTERSLAAIGMPAQGIYDAAEHALADAYANPRQASREDIARLLRAAFTGEMPA