Protein
Tudor domain-containing protein 7A
Function
Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Probably required during spermatogenesis (By similarity). Required for structural integrity of granules in primordial germ cells (PGCs).
Similarity
Belongs to the TDRD7 family.
Sequence
MSDVELVKKMLRAVLQSSKHGVAMARLQGDYRALTGEMIPFRKFGHDTLESFLRSIPGVVRLERSITGEVMCFAGVCEETAHIAQLVARQKNVKKTGCSKLLNFQMRARTSHLFSHNVKPRLSLRQPSNMTHPGRGSVTSFYSTQRKLYSNDLPSSRAPAWQMNRKSPVPEKTSVVPSKINTNIKTPLKKTSGTAAQQKPVNRADVELVQGRIKQLLQKYSSGVWLSKIPQLYKSMFQEELHIIQEVEKWTHICTVEKPGSNNIVDRLVYPVLEPVPKASPVPVKSPCKQSPNTALLKQPTLTQKTTRTFRTLAINIPQSTPKPQTPLSPTSPNSTMIDFTLSETPKTQSLSPITPPSTPPAHQPLTTELKQKLRQLLNKYSQGLWAHGLPQLFQEAFGCAFPQYVLEDLSLLADTCMVEYPMPDNRKRAILYTLPCQVQTQPRSRPPPLVLPCTSNPHVPPLIIPTADFHSVFVIEINSTNNVVVRFAGGGYSKSLEVMEEEMQNFYNNIGAGLCLLSPKIGQLVAVASSDGAMLRAQVHQLSEDKVKVYFLDHGFFDLVSRKTLFQLRDQFMTLPFQATTCQLAGLEPFSTDPVVLKTLQSLAVGRSLLAEIVEREDTPLVVLYDTSENDDVNVTAMCLKALQDKSMENPLQVNSVYTNVCVTNVCSDGSVYCQLPSRGQAKLKDIMDKIEAHFISQLTWELLVSRPFCGKVCLAKYKGKWARAEIINLHGSHVLDILFLDLGLPASLEVSELREIPPIFLKELITIPPQAIKCLLEDLNVDRAVWPPEAVLWLRETVHNKAPSCMKIVKLDETRTVHIYLFCGNEAQDIHDSVNRQLASCPFWKQDVYANKINKASELFLPDAGEPSGSSPAPSNALTLPPQLNLPLVGQNMDVFVSVACHPGHFVLQPWQDLYKLVVLMGEMVLFYNKQEVTTVDIQKNNVYAAKIDNNWHRVLVKGLLTNGLVSVYELDYGKYELINYTQLQPLIEEFRQLPFQGISAQLADVKKEVWCEEASMVFRNHVEKKPLVAQIESVEEGEWPWERKISVYLVDTTQENKDIWIHNIMKEFLDEISRDA