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sulA

Gene
sulA
Protein
Dihydropteroate synthase
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Length
314 amino acids
Function
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Similarity
Belongs to the DHPS family.
Mass
34.403 kDa
Sequence
MSSKANHAKTVICGIINVTPDSFSDGGQFFALEQALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAALAAGADLVNDITGLMGDEKMAYVVAEARAKVVIMFNPVMARPQHPSSLIFPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK

Gene
sulA
Protein
Dihydropteroate synthase
Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Length
314 amino acids
Function
Is the target for the sulfonamide group of antimicrobial drugs. Sulfonamide drugs act as pABA analogs, they inhibit the reaction by acting as alternative substrates, leading to a dead end sulfa-pterin product.
Similarity
Belongs to the DHPS family.
Mass
34.418 kDa
Sequence
MSSKANHAKTVICGIINVTPDSFSDGGQFFALEQALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAALAAGADLVNDITGLMGDEKMPHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Length
177 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.94 kDa
Sequence
MGIQSSWFYSSKHQSAKREGMVKEGKGGIVSELIYSNNQYSDNQYSDNQAVINRILLPLLRQSGNEARWLLWVSPHKKLSRQWLINSGLPLDKIIQLNRMSSITTVEAMERALASGNYSVVLGWLPTLSGKDTVRLQAAAQKGNALGFIMRPQDVSKETSRAESRSDLLKIHSIHYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella typhi
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Shigella boydii serotype 4 (strain Sb227)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.831 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHTTRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Shigella flexneri serotype 5b (strain 8401)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.861 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLTDDLTEEEHAELVDAANEGNAMGFIMRPVSASSHTTRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Shigella flexneri
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.861 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLTDDLTEEEHAELVDAANEGNAMGFIMRPVSASSHTTRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Shigella sonnei (strain Ss046)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Klebsiella aerogenes
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.18 kDa
Sequence
MFTSAHANRSPLTSASVRRPSHSVVEHSATGLISEIVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSKEWVQSSGLPLSKVMQINQMSPCNTLESMIRALRTGNYNVVIGWLTDELTEQEHERLALAAEEGHPMGFIMRPVRNTSQPGRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Klebsiella pneumoniae (strain 342)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.968 kDa
Sequence
MFTSAHANRSAQASASAGHYAHRSGEQTANGLISEIVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQSAGLPLSKVMQISQLSPCHTVDSMIRALRTGNYSVVICWLTEELTAEEHERLVNAAQEGCAMGFIMRPVRNQGTLGRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.929 kDa
Sequence
MFTSAHANRSAQASAPAGHYAHRSGEQNTNGLISEIVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQSAGLPLSKVMQISQLSPSHTIDSMIRALRTGNYSVVICWLAEELTADEHERLVNAAQVGSAMGFIMRPVRNQGTLGRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella agona (strain SL483)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.885 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARAATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRHLGQQSRWQLWLTPQQKLSREWVQSAGLPLTKVMQISQLAPPHTLESMIRALRTGNYSVVIGWLTEELTEEEHASLVEAANVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella choleraesuis (strain SC-B67)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.994 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMHPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella dublin (strain CT_02021853)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.003 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALSRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella enteritidis PT4 (strain P125109)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.003 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALSRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.96 kDa
Sequence
MYTSGYANRSSSFPTTTHNAALTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALSRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella heidelberg (strain SL476)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella newport (strain SL254)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella paratyphi C (strain RKS4594)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.994 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMHPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella paratyphi A (strain AKU_12601)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Salmonella schwarzengrund (strain CVM19633)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.013 kDa
Sequence
MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.887 kDa
Sequence
MYTSGYANRSSLFSSTAGSIARVSSENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQSAGLPLTKVMQISQLSPCHTLESMIRALRTGNYSVVIGWLADELSEEEHTRLAQAADEGNAMGFIMRPVSAHAHATRHHSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.771 kDa
Sequence
MYTSGYAHRDSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTAEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.843 kDa
Sequence
MYTAGYAHRDSSFSSTASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain 55989 / EAEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O157:H7
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O157:H7 (strain EC4115 / EHEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.813 kDa
Sequence
MYTSGYAHRASSFSSAASKIVRVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O81 (strain ED1a)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.743 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTAEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O8 (strain IAI1)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain K12 / MC4100 / BW2952)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain K12 / DH10B)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O9:H4 (strain HS)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O1:K1 / APEC
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.843 kDa
Sequence
MYTAGYAHRDSSFSSTASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.743 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTAEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.743 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTAEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain K12)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU) (PubMed:22515815).
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain SE11)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.801 kDa
Sequence
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia coli (strain UTI89 / UPEC)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.843 kDa
Sequence
MYTAGYAHRDSSFSSTASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Enterobacter sp. (strain 638)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.94 kDa
Sequence
MHTSIYANRSTSFSPSAGNDTQNTFGRVSTGMISEVVYREDQPLMTQLLLLPLLQQLGQQSRWQLWLTPKQKLSREWVQSAGLPLAKVMQISQIAPCHTVDSMIRALRTGNYSVVIGWLSEELTEDEHFRLVEAAEEGNAIGLIMRPVNPDSLGRGHLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Length
169 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.915 kDa
Sequence
MYTSGYANRSSSFSTAVNNTARVATTNTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLSKVMQINQLSPCHTVESMIRALRTGNYSVVIGWLAEELTEEEHAELVNAANEGNAMGFIMRPVSARTHATRQLSGLKIHSNLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Serratia marcescens
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.116 kDa
Sequence
MRTQSLYQPHFGHGSYTTRNVAKNTDIGKENGLISELVYNERQPAVAQLLLPLLLQLGKQSRWLLWLTPQQKLSKQWLQQSGLPVDKMVQLSQISPVNTVEAMEKALQTGNYSVVLGWLPELTEEDRLKLRRAAELGNAYGFIMRPQRDISPTHGHCSTLKIHSSLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Serratia proteamaculans (strain 568)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.96 kDa
Sequence
MRTQSLYNTHFSHTSFAVSNAAESTNDGKENGLISELVYNEHQPAVVQLLLPLLQQLGMQSRWLLWLTPQQKLSKLWLQQSGLPVGKVVQLSQINSLDTVEAMEKALLTGNYSVVLGWLPDLTEEDRLKLRRAAELGNAYGFIMRPQRDINPVHGHCSTLKIHSSLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.027 kDa
Sequence
MRTQSLKPYNANYHSLITRDAQERVDAPTDSGLISELVYSENQPAVAQLLLPLLQQLGKQSRWLLWLTPQQKLSRLWLQQSGLPMSKVVQARQINPLSTVDAMEKALLTGNYSVVLGWLPELSENDRIRLRMAAKLGNAYGFVMRPLNETKLDQGQCATLKIHSSLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.03 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pestis bv. Antiqua (strain Antiqua)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.06 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.06 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pestis
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.06 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pestis bv. Antiqua (strain Angola)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.06 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.06 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pestis (strain Pestoides F)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.06 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.03 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.03 kDa
Sequence
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.852 kDa
Sequence
MSTQSVSSHNIESSSFSANQHAAEPSVATGGIISEIVYNADQPIVTHLLLPLLQQLGTQSRWLLWLSPQQRLSRPWVQQSGLPLDKMVQLHHINPLFTVDAMERALLTGNYSAVLCWLPHELTEEEKVRLRHAAQAGNTYGFIMRPESAGDDAYRLFPSLKIHSTLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.869 kDa
Sequence
MRTQSISSHNVQSSSFSANQHAAETSISAGGIISEIVYNADQPIVTHLLLPLLQQLGTQSRWLLWLSPQQKLSRPWVQQSGLPLDKMVQLHHINPLFTVDAMERALLTGNYSAVLCWLPHELTEEEKVRLRHAAQAGNTYGFIMRPESTGGDAYRLFPSLKIHSTLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Cronobacter sakazakii (strain ATCC BAA-894)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.062 kDa
Sequence
MYSSHQNRAYGSRRLAKETAGALAQAETRGLISEVMYNEDQPWMTQLVLLPLLQQLGQQSRWQLWLTPQQRLSREWVESAGLPLTKVMQVSQMNPQVTLDSMIRALETGNYSVVIAWLHDDLTDDEHRRLTAAAEKGNAMGFLMRPVQPSLPGDRPRSALRIHSGMVH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Cronobacter turicensis (strain DSM 18703 / LMG 23827 / z3032)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
19.27 kDa
Sequence
MYFSHQNRAHGSRRLAKETADALAQAETRGLISEVMYNEDQPRMTQMVLLPLLQQLGLQSRWQLWLTPQQRLSREWVESAGLPLTKVMQVSQMNPQVTLDSMIRALETGNYSVVIAWLHDDLTDDEHRRLTEAAEKGNAMGFLMRPVQPSLPGDRPRSGLRIHSRMVH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Edwardsiella tarda (strain EIB202)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity).
Similarity
Belongs to the SulA family.
Mass
18.274 kDa
Sequence
MRTSPLHPATDSVVFSRPACQSAPTVPQSGFVSELGYGAQQPLLSLLLPPLLRQLGEQSRWQLWITAQHKPSKRWLSACGVPVHKVMQLRRAEAGEAIYAMEQALRSGNYSVVLGWLPPLTAAERLRLNRAAQAGRSIGLLMQPQEGKLAAAAPPQAHAANRGSARYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Edwardsiella tarda (strain FL6-60)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity).
Similarity
Belongs to the SulA family.
Mass
18.274 kDa
Sequence
MRTSPLHPATDSVVFSRPACQSAPTVPQSGFVSELGYGAQQPLLSLLLPPLLRQLGEQSRWQLWITAQHKPSKRWLSACGVPVHKVMQLRRAEAGEAIYAMEQALRSGNYSVVLGWLPPLTAAERLRLNRAAQAGRSIGLLMQPQEGKLAAAAPPQAHAANRGSARYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Erwinia pyrifoliae (strain DSM 12163 / CIP 106111 / Ep16/96)
Length
168 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
Similarity
Belongs to the SulA family.
Mass
18.853 kDa
Sequence
MRTHFMKNQSVKRNQHVSTPAIPASICADGLISELVHNEDHPGMTQLLLLPLLQQLGTQSRWQLWLTSQQKLSRDWLLRSGLPLDKVMQSPYCGTITTVEAMIKALQTGNYSVVLGWLADEISETERKRLQQAAKSGQALGLIMRSECNVLPSARPLHGLRIQSSLYH

Gene
sulA
Protein
Cell division inhibitor SulA
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
161 amino acids
Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity).
Similarity
Belongs to the SulA family.
Mass
17.476 kDa
Sequence
MQTSHSLPSAQLPLFQEAFWASNGAPLLDDVIDSPSSASIEEPAAFSELSLSGLPGHCLTLLAPILRELSEEQDARWLTLIAPPASLTHEWLRRAGLNRERILLLQAKDNAAALALSCEALRLGRSHTVVSWLEPLSRAARKQLSRAAQLGQAQSLNIRLG