strM

Gene

strM

Protein

dTDP-4-dehydrorhamnose 3,5-epimerase

Organism

Streptomyces griseus

Length

200 amino acids

Function

Involved in the biosynthesis of the dihydrostreptose moiety of streptomycin (PubMed:1661369). Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose (By similarity).

Similarity

Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

Mass

21.956 kDa

Sequence

MRPLSVQGAWLSETRAFADDRGEFQELYSARSLRGALGYDPGVAQVNRSVSRRGVLRGVHFAQLPPSQAKYVTCLSGAVLDVVVDIRTGSPTYRAWEAVRLDDPHRSLYVEAGLGHSFMALTDDAVVVYLTSQGYAAGREHGVHPLDPDLGIAWPDGIEPVLSEKDRQAPGIAEMERRGLLPDYEECLAFRRSLCERGTG

Protein

dTDP-4-dehydrorhamnose 3,5-epimerase: strM