Protein
Serrate RNA effector molecule homolog B
Function
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity).
Similarity
Belongs to the ARS2 family.
Sequence
MADSDDEHDRRRRDKFRRERSDYDRSREREERRRDDWSDREWDRGRERRSRGEYRDYESRSRRDRFSPQRHDISPPQKRMRRDWDDHGSDPYHSGYEMPYSSSAGPAYGPPQPWGHPEMHVMQHHGIPIQARLGNLHDVDLGTPAPTMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESRASLHNRLNAFMFLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILDEEEEEAKREAAKKEEARVTETEKVITEEKEAPAKPEKDKEPESEEKPVKPEEEEEKKVEKEEPERETRKPGTRKRKRSGDSDDGSDSESDTETASPKPETPNQNGCEDTPKKEEETEKPKEKPKEDTVKPRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITLHRPIVRNDIKLAARLIHALDERAQLWEGEQGDQVVSAQNPILKNITDYLIDEVNAEEEELLSSAGRTPETEAPKEGNPTEITVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGPLPPNRVSHGEVTEWQKTIEEKLAPLFAVRETLSEDEAMKMGKKDPEQEAEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVEFFNNYLTDSKRPALPEVKPLQPPGGAAGQALAAGLLYPPQGPQALLPYGQPRPPVLGYGGAPQFPPNPYGAGRGNYDSFRGQGMYPGKPRNRMMRGDPRSIIEYRDLDAPDDVDFF