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spdya-b

Gene
spdya-b
Protein
Speedy protein 1-B
Organism
Xenopus laevis
Length
298 amino acids
Function
Stimulates oocyte maturation by promoting meiotic G2/M progression in resting oocytes, via activation of the MAPK cascade and cdc2-cyclin B. Also activates the kinase activity of cdk2; this activation does not appear necessary for oocyte maturation. Necessary for polyadenylation in oocytes.
Similarity
Belongs to the Speedy/Ringo family.
Mass
34.554 kDa
Sequence
MRHMQSATRATLVCGSGVKQIIAKGHPNTRVFGARKARIPEREVLAAKPKITRITHLNLQPQERQAFYRLLENELIQEFLSMDSCLKISDKYLIAMVLAYFKRAGLYTGEYTTMNFFVALYLANDMEEDEEDYKYEIFPWALGDSWREFFPQFLRLRDNFWAKMNYRAVVSRRCCDEVMAKDPTHWAWLRDRPIHHSGALRGYLRNEDDFFPRGPGLTPASCALCHKASVCDSGGVAHDNSSPEQEIFHYTNREWSQELLILPPELLLDPESTYDIHIFQEPLVGLEPDGAALEWHHL