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slbp1

Gene
slbp1
Protein
Histone RNA hairpin-binding protein
Organism
Xenopus laevis
Length
254 amino acids
Function
Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3' end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP) (By similarity). Could play an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression.
Similarity
Belongs to the SLBP family.
Mass
29.726 kDa
Sequence
MSDHWRTISEEHRPHAPSRWSQGRKRCSDGKLRRHDDTDSTVFDTKPSEEPQARPDSFTTPESHKPVARCKDWGSAVEEDEQLREKVDQDIARYRRKLLINEFGRRERRSSSGSSDSKDSSTHGEMETDPAVITRRQKQINYGKNTIAYDRYIKAVPRHLREPNVHPRTPNKFKKYSRRSWDQQIRLWRIALHQWDPPAAEGSDLQPFMEEDMVCTETSSQENLFTGTPTKVRKVEADDAFDLEPCFIEEELLS