sir2D

Gene

sir2D

Protein

NAD-dependent deacetylase sir2D

Organism

Dictyostelium discoideum

Length

542 amino acids

Function

NAD-dependent deacetylase, which plays an important role in the regulation of transcriptional repression.

Similarity

Belongs to the sirtuin family.

Mass

62.142 kDa

Sequence

MNKRSLENNELNEIQNNQNKNNNNKINKEIPSDNTPLKKLKSINSLEQLQEVDEDEDLDVEIDTKLINKLDKKGRKYEFVGEGYSDEEQISDDYEDDESSEYEYGYENEDELLDDEDHLDNINEIKKIQKKLVNTETSTSITNTSSTTTTSTSTTTTTTTKTQINETILLDILNNNKDEVDDEIQRIGNNVGNSKEEEGEEEEENIELVARSFIYKHIQEKKSLGIDPIEFTKDIGFKLELEKDDDAWEIITAFLTRKKVAVNLFLNYLKYNTLARPYRKKIATLDLSTFEKVCQLFESSKNIVIITGAGVSVSCGIPDFRSKGGVYETIEKKYNLPRPESLFDIHYLRANPLPFFEFAKEIFPGNHKPSPTHSFIKLLDEKGKLLRNYTQNIDTLEHVAGIDREKLVNCHGSFSTATCITCKLTVDGTTIRDTIMKMEIPLCQQCNDGQSFMKPDIVFFGENLPDRFDQCVLKDVKDIDLLIVMGSSLQVQPVSLLPDIVDKQIPQILINRELVAQPHEFDYVYLGDCDQFVQDLLNKVKW

Protein

NAD-dependent deacetylase sir2D: sir2D