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sigB

Gene
SIGB
Protein
RNA polymerase sigma factor sigB
Organism
Arabidopsis thaliana
Length
572 amino acids
Function
Required for the transition of plastids into chloroplasts by coordinating nuclear and chloroplastic genomes under light conditions. Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released. Promotes the biosynthesis of plastid-encoded tRNAs (e.g. trnE-UUC and trnV-UAC).
Similarity
Belongs to the sigma-70 factor family.
Mass
64.054 kDa
Sequence
MSSCLLPQFKCPPDSFSIHFRTSFCAPKHNKGSVFFQPQCAVSTSPALLTSMLDVAKLRLPSFDTDSDSLISDRQWTYTRPDGPSTEAKYLEALASETLLTSDEAVVVAAAAEAVALARAAVKVAKDATLFKNSNNTNLLTSSTADKRSKWDQFTEKERAGILGHLAVSDNGIVSDKITASASNKESIGDLESEKQEEVELLEEQPSVSLAVRSTRQTERKARRAKGLEKTASGIPSVKTGSSPKKKRLVAQEVDHNDPLRYLRMTTSSSKLLTVREEHELSAGIQDLLKLERLQTELTERSGRQPTFAQWASAAGVDQKSLRQRIHHGTLCKDKMIKSNIRLVISIAKNYQGAGMNLQDLVQEGCRGLVRGAEKFDATKGFKFSTYAHWWIKQAVRKSLSDQSRMIRLPFHMVEATYRVKEARKQLYSETGKHPKNEEIAEATGLSMKRLMAVLLSPKPPRSLDQKIGMNQNLKPSEVIADPEAVTSEDILIKEFMRQDLDKVLDSLGTREKQVIRWRFGMEDGRMKTLQEIGEMMGVSRERVRQIESSAFRKLKNKKRNNHLQQYLVAQS

Gene
sigB
Protein
RNA polymerase sigma-B factor
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
332 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
Similarity
Belongs to the sigma-70 factor family.
Mass
38.432 kDa
Sequence
MPNSTSQVTKLKSKNNEFSYTADAVSIYLHKIGRVPLLSHEQEIFFAQQVQQMMVMFTAKEELAEKLQREPTLQEWADKMQLKEDVLLQQLSQGQIAKQKMIQANLRLVVSIAKKYQKRNLEFLDLIQEGALGLERGVEKFDPTLGYKFSTYAYWWIRQGITRAIAQQSRTIRLPIHMADKLNKIKCVQRELSQKLGYIAGVTEIAQALNLEPSQIREYLQLVRQPVSLDMRIGFEQDTQLQDLLKDDGMSPERYAERELLYQDIHNLLAKLTPQQKEVLILRFGLAGGCELTLVQISQRMGISRERVRQVEKQALTLLRRYGIDSRSYLAD

Gene
sigB
Protein
RNA polymerase sigma factor SigB
Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Length
329 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
Similarity
Belongs to the sigma-70 factor family.
Mass
37.35 kDa
Sequence
MTSPSDVEASTETVDRGSRRNQTNDNPSADLVRVYLNGIGKTALLNAEDEVELAQTIEVGLYAEYLLENSQEPLTRAMKRDLKVLVKEGRKARSHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYSKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLSRIKREMYQQLGREATNEELAEESGIEESKIEMLLRQSRDPVSLDMPVGADEEAPLGDFIEDSEATDAESAVVASLRHSDIRTVLDTLEQREQDVIRLRYGLDDGVPRTLDQIGRQFGLSRERVRQIEREVMSKLRDGARAEKLRAYAQ

Gene
sigB
Protein
RNA polymerase sigma factor SigB
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
323 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. A non-essential principal sigma factor that responds to cell envelope stress and hypoxia (By similarity).
Similarity
Belongs to the sigma-70 factor family.
Mass
36.343 kDa
Sequence
MADAPTRATTSRVDSDLDAQSPAADLVRVYLNGIGKTALLNAAGEVELAKRIEAGLYAEHLLETRKRLGENRKRDLAAVVRDGEAARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLARIKREMHQHLGREATDEELAAESGIPIDKINDLLEHSRDPVSLDMPVGSEEEAPLGDFIEDAEAMSAENAVIAELLHTDIRSVLATLDEREHQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQIERDVMSKLRHGERADRLRSYAS

Gene
sigB
Protein
RNA polymerase sigma factor SigB
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
323 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. A non-essential principal sigma factor that responds to cell envelope stress and hypoxia. Controls a regulon of about 40 genes, with another 100 genes expression being altered during SDS stress and about 50 gene being altered during diamide (oxidative) stress.
Similarity
Belongs to the sigma-70 factor family.
Mass
36.343 kDa
Sequence
MADAPTRATTSRVDSDLDAQSPAADLVRVYLNGIGKTALLNAAGEVELAKRIEAGLYAEHLLETRKRLGENRKRDLAAVVRDGEAARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLARIKREMHQHLGREATDEELAAESGIPIDKINDLLEHSRDPVSLDMPVGSEEEAPLGDFIEDAEAMSAENAVIAELLHTDIRSVLATLDEREHQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQIERDVMSKLRHGERADRLRSYAS

Gene
sigB
Protein
RNA polymerase sigma-B factor
Organism
Stigmatella aurantiaca (strain DW4/3-1)
Length
296 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
Similarity
Belongs to the sigma-70 factor family.
Mass
33.298 kDa
Sequence
MQISNDPSSHSGSLTMYLSEINQYGLLSVEEEQALARKFVKGDLAAGHRLVTSNLRFVVKVSYEYRSYGIKMSDLIQEGNIGLMKAVQKFDPDKGIRLISYAVWWIRAYIQNYILKSWSLVKLGTTQAQRKLFFSLARTRRELEKFGAGDGAVVNVDEIANKLNVKASEVREMEQRMGGRDLSLDAPMGEDGGNSHVDFVASAAAPQDDEFADKEEAGLINSRVHMALMRLDPRERFIIEQRVMNERPMTLKELGEHFGFSRERARQLEIRAKDKLKAELAALLAEVDPDAAAALQ

Gene
sigB
Protein
RNA polymerase sigma-B factor
Organism
Bacillus subtilis (strain 168)
Length
262 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon.
Similarity
Belongs to the sigma-70 factor family. SigB subfamily.
Mass
29.901 kDa
Sequence
MTQPSKTTKLTKDEVDRLISDYQTKQDEQAQETLVRVYTNLVDMLAKKYSKGKSFHEDLRQVGMIGLLGAIKRYDPVVGKSFEAFAIPTIIGEIKRFLRDKTWSVHVPRRIKELGPRIKMAVDQLTTETQRSPKVEEIAEFLDVSEEEVLETMEMGKSYQALSVDHSIEADSDGSTVTILDIVGSQEDGYERVNQQLMLQSVLHVLSDREKQIIDLTYIQNKSQKETGDILGISQMHVSRLQRKAVKKLREALIEDPSMELM

Gene
sigB
Protein
RNA polymerase sigma-B factor
Organism
Bacillus anthracis
Length
257 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
Similarity
Belongs to the sigma-70 factor family. SigB subfamily.
Mass
29.301 kDa
Sequence
MEIQSQPTNLTKEDVIKLIAEFQQNQCGEAQERLVDHYKNLVYSIAYRYSKGGPMHEDIIQVGMLGLLGAIRRYDYSIGNAFEPFAIPTIVGEIKKYLRDKTWGIHVPRRIKDLGGKIKLAIEELTDHLQRSPKIIEIADHLGLSEEEVLEIMDAKNNYRVSSLDDVVENASDGSSVARIESVGEVEQGYEQTERRLVLKDIFNVLNETEKSVIHYIFEENLNQKDTGERLGISQMHVSRIKRQAISKLKQAAFLDT

Gene
sigB
Protein
RNA polymerase sigma-B factor
Organism
Myxococcus xanthus
Length
246 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is essential for late-stage differentiation of M.xanthus.
Similarity
Belongs to the sigma-70 factor family.
Mass
27.841 kDa
Sequence
MVTANLRFVVKVAYEYRSYGIKMSDLIQEGNIGLMKAVQKFDPDKGIRLISYAVWWIRAYIQNYILKSWSLVKLGTTQAHGKLFFSLARTRRELEKFGSGDAAVNVDDIARRLHVKPGEVREMEQRMGGRDLSLDAPMGEDGGNSHVDFVVSAAAPQDDEFADKEEAGLINARVRAALMRLDPREPFIIEQRVMNERPMTLKELGEHFGFSRERARQLEIRAKDKLKSELAALMAEVDPEAVAAQQ