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senp8

Gene
senp8
Protein
Probable sentrin-specific protease 8
Organism
Dictyostelium discoideum
Length
243 amino acids
Function
Protease that catalyzes two essential functions in the nedd8 pathway: processing of full-length nedd8 to its mature form and deconjugation of nedd8 from targeted proteins.
Similarity
Belongs to the peptidase C48 family.
Mass
28.095 kDa
Sequence
MSDPLIVSYNDSAIYQSDINILKSNQWLNDSIISFYLEWLKDGGEDNKNKIPNQVLLLSPSVVFCCSFVESEQEIQLMFEQPLSLKTKEVIFFPLTNNRDPNVIGGGTHWSLLIFIKSLNKFIYYDSINSFNSSDAIFIISKFKFLLSSPPPKTNLKEFLINQKTPQQQNGYDCGLYVLSIIEELLKLIIKENENNKGEENKISYKDLLLSEFTNELLFKEITPNYIKDKRVEILNTILKLKK

Gene
Senp8
Protein
Sentrin-specific protease 8
Organism
Mus musculus
Length
221 amino acids
Function
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Similarity
Belongs to the peptidase C48 family.
Mass
25.057 kDa
Sequence
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVCFISPEVTQFIKCTSSPAEIAMFLEPLDLPHKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSIHAKQVAEKLKAFLGSKGDKLVFVEEKAPAQENSYDCGMYVICNTEALCQSLFRRQPESPLQLLTPTYITKKRGEWKDLIARLAKKNEVATEECS

Gene
Senp8
Protein
Sentrin-specific protease 8
Organism
Rattus norvegicus
Length
217 amino acids
Function
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Similarity
Belongs to the peptidase C48 family.
Mass
24.728 kDa
Sequence
MDPVVLSYMDSLLRQSDVSLLDPPNWLNDHIIGFAFEYFASSQFHDCSDHVCFISPEVTQFIKCTSSPAEIAMFLEPLDLPHKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSIHAKQVAEKLKAFLGSKGDKLVFVEEKAPAQQNSYDCGMYVICNTEALCQNLFRRQPESPLQLLTPTYITKKRGEWKDLIARLAKKNRSSY

Gene
SENP8
Protein
Sentrin-specific protease 8
Organism
Homo sapiens
Length
212 amino acids
Function
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Similarity
Belongs to the peptidase C48 family.
Mass
24.107 kDa
Sequence
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK