Protein
Succinate--CoA ligase [ADP-forming] subunit beta
Organism
Blastocystis sp. subtype 1 (strain ATCC 50177 / NandII)
Function
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family.
Sequence
MLRMAPKTVGAVRNLNIHEWQSKQLIQKYGGRAQSGEVAFSPERSRDIAKKLWNQFPGCKFVVKAQVLAGGRGKGHWEHGMQGGVKLAKTPEEVYEIANEMIGHKLITKQTGAKGINCNKVMVCGAVKILKEFYLSILLDRAMGCPVIIATSQGGMGIEEVAQKCPECLFKVPISVKNGPTNEQLVKLAKDLGLEGDLVQDCVDNVKALYQVFDKCDSTMVEINPLGVIETPTDEKVICCLDAKIAFDKDAAFRQKEIFALRDKSREDPRDVRASLADLNYVGLDGDIGCMVNGAGLAMATMDTINYFGGSAANFLDVGGNAKKEQITEALRILNSDKHVKSILINIFGGIMRCDVVAQGIMDAVREMKLDLPLVVRLEGTNVAKGKEILKSSGLNIIPANDLGDAAKKAVASLKH