Protein
HTH-type transcriptional regulator SarX
Organism
Staphylococcus aureus (strain bovine RF122 / ET3-1)
Function
Involved in the regulation of virulence genes. Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb. Binds directly to the agr promoter region (By similarity).
Similarity
Belongs to the SarA family.
Sequence
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNDDDISKFNALFEDVEQFLNI