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sacB

Gene
sacB
Protein
Capsular polysaccharide phosphotransferase SacB
Organism
Neisseria meningitidis serogroup A
Length
545 amino acids
Function
Part of a capsular biosynthesis operon and has been suggested to be the polymerase that links individual UDP-N-acetyl-D-mannosamine monomers. In serotype A the capsule is composed of repeated units of (alpha 1-6)-linked N-acetyl-D-mannosamine-1-phosphate. Non-polar disruption of this open reading frame prevented capsule synthesis.
Similarity
Belongs to the stealth family.
Mass
64.098 kDa
Sequence
MFILNNRKWRKLKRDPSAFFRDSKFNFLRYFSAKKFAKNFKNSSHIHKTNISKAQSNISSTLKENRKQDMLIPINFFNFEYIVKKLNNQNAIGVYILPSNLTLKPALCILESHKEDFLNKFLLTISSENLKLQYKFNGQIKNPKSVNEIWTDLFSIAHVDMKLSTDRTLSSSISQFWFRLEFCKEDKDFILFSTANRYSRKLWKHSIKNNQLFKEGIRNYSEISSLPYEEDHNFDIDLVFTWVNSEDKNWQELYKKYKPDFNSDATSTSRFLSRDELKFALRSWEMSGSFIRKIFIVSNCAPPAWLDLNNPKIQWVYHEEIMPQSALPTFSSHAIETSLHHIPGISNYFIYSNDDFLLTKPLNKDNFFYSNGIAKLRLEAWGNVNGECTEGEPDYLNGARNANTLLEKEFKKFTTKLHTHSPQSMRTDILFEMEKKYPEEFNRTLHNKFRSLDDIAVTGYLYHHYALLSGRALQSSDKTELVQQNHDFKKKLNNVVTLTKERNFDKLPLSVCINDGADSHLNEEWNVQVIKFLETLFPLPSSFEK
Protein
Capsular polysaccharide phosphotransferase SacB: sacB

Gene
sacB
Protein
Capsular polysaccharide phosphotransferase SacB
Organism
Neisseria meningitidis serogroup A
Length
545 amino acids
Function
May be the polymerase that links individual UDP-N-acetyl-D-mannosamine monomers. In serotype A the capsule is composed of repeated units of (alpha 1-6)-linked N-acetyl-D-mannosamine-1-phosphate (By similarity).
Similarity
Belongs to the stealth family.
Mass
64.134 kDa
Sequence
MFILNNRKWRKLKRDPSAFFRDSKFNFLRYFSAKKFAKNFKNSSHIHKTNISKAQSNISSTLKQNRKQDMLIPINFFNFEYIVKKLNNQNAIGVYILPSNLTLKPALCILESHKEDFLNKFLLTISSENLKLQYKFNGQIKNPKSVNEIWTDLFSIAHVDMKLSTDRTLSSSISQFWFRLEFCKEDKDFILFPTANRYSRKLWKHSIKNNQLFKEGIRNYSEISSLPYEEDHNFDIDLVFTWVNSEDKNWQELYKKYKPDFNSDATSTSRFLSRDELKFALRSWEMNGSFIRKIFIVSNCAPPAWLDLNNPKIQWVYHEEIMPQSALPTFSSHAIETSLHHIPGISNYFIYSNDDFLLTKPLNKDNFFYSNGIAKLRLEAWGNVNGECTEGEPDYLNGARNANTLLEKEFKKFTTKLHTHSPQSMRTDILFEMEKKYPEEFNRTLHNKFRSLDDIAVTGYLYHHYALLSGRALQSSDKTELVQQNHDFKKKLNNVVTLTKERNFDKLPLSVCINDGADSHLNEEWNVQVIKFLETLFPLPSSFEK
Protein
Capsular polysaccharide phosphotransferase SacB: sacB

Gene
sacB
Protein
Capsular polysaccharide phosphotransferase SacB
Organism
Neisseria meningitidis serogroup A
Length
545 amino acids
Function
May be the polymerase that links individual UDP-N-acetyl-D-mannosamine monomers. In serotype A the capsule is composed of repeated units of (alpha 1-6)-linked N-acetyl-D-mannosamine-1-phosphate (By similarity).
Similarity
Belongs to the stealth family.
Mass
64.13 kDa
Sequence
MFILNNRKWRKLKRDPSAFFRDSKFNFLRYFSAKKFAKNFKNSSHIHKTNISKAQSNISSTLKQNRKQDMLIPINFFNFEYIVKKLNNQNAIGVYILPSNLTLKPALCILESHKEDFLNKFLLTISSENLKLQYKFNGQIKNPKSVNEIWTDLFSIAHVDMKLSTDRTLSSSISQFWFRLEFCKEDKDFILFPTANRYSRKLWKHSIKNNQLFKEGIRNYSEISSLPYEEDHNFDIDLVFTWVNSEDKNWQELYKKYKPDFNSDATSTSRFLSRDELKFALRSWEMNGSFIRKIFIVSNCAPPAWLDLNNPKIQWVYHEEIMPQSALPTFSSHAIETSLHHIPGISNYFIYSNXDFLLTKPLNKDNFFYSNGIAKLRLEAWGNVNGECTEGEPDYLNGARNANTLLEKEFKKFTTKLHTHSPQSMRTDILFEMEKKYPEEFNRTLHNKFRSLDDIAVTGYLYHHYALLSGRALQSSDKTELVQQNHDFKKKLNNVVTLTKERNFDKLPLSVCINDGADSHLNEEWNVQVIKFLETLFPLPSSFEK
Protein
Capsular polysaccharide phosphotransferase SacB: sacB

Gene
sacB
Protein
Capsular polysaccharide phosphotransferase SacB
Organism
Neisseria meningitidis serogroup A
Length
545 amino acids
Function
May be the polymerase that links individual UDP-N-acetyl-D-mannosamine monomers. In serotype A the capsule is composed of repeated units of (alpha 1-6)-linked N-acetyl-D-mannosamine-1-phosphate (By similarity).
Similarity
Belongs to the stealth family.
Mass
64.135 kDa
Sequence
MFILNNRKWRKLKRDPSAFFRDSKFNFLRYFSAKKFAKNFKNSSHIHKTNISKAQSNISSTLKQNRKQDMLIPINFFNFEYIVKELNNQNAIGVYILPSNLTLKPALCILESHKEDFLNKFLLTISSENLKLQYKFNGQIKNPKSVNEIWTDLFSIAHVDMKLSTDRTLSSSISQFWFRLEFCKEDKDFILFPTANRYSRKLWKHSIKNNQLFKEGIRNYSEISSLPYEEDHNFDIDLVFTWVNSEDKNWQELYKKYKPDFNSDATSTSRFLSRDELKFALRSWEMNGSFIRKIFIVSNCAPPAWLDLNNPKIQWVYHEEIMPQSALPTFSSHAIETSLHHIPGISNYFIYSNDDFLLTKPLNKDNFFYSNGIAKLRLEAWGNVNGECTEGEPDYLNGARNANTLLEKEFKKFTTKLHTHSPQSMRTDILFEMEKKYPEEFNRTLHNKFRSLDDIAVTGYLYHHYALLSGRALQSSDKTELVQQNHDFKKKLNNVVTLTKERNFDKLPLSVCINDGADSHLNEEWNVQVIKFLETLFPLPSSFEK
Protein
Capsular polysaccharide phosphotransferase SacB: sacB

Gene
sacB
Protein
Capsular polysaccharide phosphotransferase SacB
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
545 amino acids
Function
May be the polymerase that links individual UDP-N-acetyl-D-mannosamine monomers. In serotype A the capsule is composed of repeated units of (alpha 1-6)-linked N-acetyl-D-mannosamine-1-phosphate (By similarity).
Similarity
Belongs to the stealth family.
Mass
64.134 kDa
Sequence
MFILNNRKWRKLKRDPSAFFRDSKFNFLRYFSAKKFAKNFKNSSHIHKTNISKAQSNISSTLKQNRKQDMLIPINFFNFEYIVKKLNNQNAIGVYILPSNLTLKPALCILESHKEDFLNKFLLTISSENLKLQYKFNGQIKNPKSVNEIWTDLFSIAHVDMKLSTDRTLSSSISQFWFRLEFCKEDKDFILFPTANRYSRKLWKHSIKNNQLFKEGIRNYSEISSLPYEEDHNFDIDLVFTWVNSEDKNWQELYKKYKPDFNSDATSTSRFLSRDELKFALRSWEMNGSFIRKIFIVSNCAPPAWLDLNNPKIQWVYHEEIMPQSALPTFSSHAIETSLHHIPGISNYFIYSNDDFLLTKPLNKDNFFYSNGIAKLRLEAWGNVNGECTEGEPDYLNGARNANTLLEKEFKKFTTKLHTHSPQSMRTDILFEMEKKYPEEFNRTLHNKFRSLDDIAVTGYLYHHYALLSGRALQSSDKTELVQQNHDFKKKLNNVVTLTKERNFDKLPLSVCINDGADSHLNEEWNVQVIKFLETLFPLPSSFEK
Protein
Capsular polysaccharide phosphotransferase SacB: sacB

Gene
sacB
Protein
Levansucrase
Organism
Bacillus subtilis (strain 168)
Length
473 amino acids
Similarity
Belongs to the glycosyl hydrolase 68 family.
Mass
52.971 kDa
Sequence
MNIKKFAKQATVLTFTTALLAGGATQAFAKETNQKPYKETYGISHITRHDMLQIPEQQKNEKYQVPEFDSSTIKNISSAKGLDVWDSWPLQNADGTVANYHGYHIVFALAGDPKNADDTSIYMFYQKVGETSIDSWKNAGRVFKDSDKFDANDSILKDQTQEWSGSATFTSDGKIRLFYTDFSGKHYGKQTLTTAQVNVSASDSSLNINGVEDYKSIFDGDGKTYQNVQQFIDEGNYSSGDNHTLRDPHYVEDKGHKYLVFEANTGTEDGYQGEESLFNKAYYGKSTSFFRQESQKLLQSDKKRTAELANGALGMIELNDDYTLKKVMKPLIASNTVTDEIERANVFKMNGKWYLFTDSRGSKMTIDGITSNDIYMLGYVSNSLTGPYKPLNKTGLVLKMDLDPNDVTFTYSHFAVPQAKGNNVVITSYMTNRGFYADKQSTFAPSFLLNIKGKKTSVVKDSILEQGQLTVNK
Protein
Levansucrase: sacB

Gene
sacB
Protein
Inactive levansucrase
Organism
Geobacillus stearothermophilus
Length
473 amino acids
Similarity
Belongs to the glycosyl hydrolase 68 family.
Mass
52.855 kDa
Sequence
MNIKKFAKQATVLTFTTALLAGGATQAFAKETNQKPYKETYGISHITRHDMLQIPEQQKNEKYQVPEFDSSTIKNISSAKGLDVWDSWPLQNADGTVANYHGYHIVFALAGDPKNADDTSIYMFYQKVGETSIDSWKTPGRVFKDSDKFDANDSILKDQTQEWSGSATFTSDGKIRLFYTDFSGKHYGKQTLTTAQVNVSASDSSLNINGVEDYKSIFDGDSKTYQNVQQFIDEGNYSSGDNHTLRDPHYVEDKGHKYLVFEANTGTEDGYQGEESLFNKAYYGKSTSFFRQESQKLLQSDKNRTAELANGALGMIELNDDYTLKKVMKPLIASNTVTDEIERANVFKMNGKWYLSTDSRGSQMTIDGITSNDIYMLGYVSNSLTGPYKPLNKTGLVLKMDLDPNDVTFTYSHFAVPQATGNNVVITSYMTNRGFYADKQSTFAPSFLLNIQGKKTSVVKASILDQGQLTVNQ
Protein
Inactive levansucrase: sacB

Gene
sacB
Protein
Levansucrase
Organism
Bacillus amyloliquefaciens
Length
472 amino acids
Similarity
Belongs to the glycosyl hydrolase 68 family.
Mass
52.859 kDa
Sequence
MNIKKIVKQATVLTFTTALLAGGATQAFAKENNQKAYKETYGVSHITRHDMLQIPKQQQNEKYQVPQFDQSTIKNIESAKGLDVWDSWPLQNADGTVAEYNGYHVVFALAGSPKDADDTSIYMFYQKVGDNSIDSWKNAGRVFKDSDKFDANDPILKDQTQEWSGSATFTSDGKIRLFYTDYSGKHYGKQSLTTAQVNVSKSDDTLKINGVEDHKTIFDGDGKTYQNVQQFIDEGNYTSGDNHTLRDPHYVEDKGHKYLVFEANTGTENGYQGEESLFNKAYYGGGTNFFRKESQKLQQSAKKRDAELANGALGIIELNNDYTLKKVMKPLITSNTVTDEIERANVFKMNGKWYLFTDSRGSKMTIDGINSNDIYMLGYVSNSLTGPYKPLNKTGLVLQMGLDPNDVTFTYSHFAVPQAKGNNVVITSYMTNRGFFEDKKATFGPSFLMNIKGNKTSVVKNSILEQGQLTVN
Protein
Levansucrase: sacB

Gene
sacB
Protein
Levansucrase
Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1)
Length
423 amino acids
Similarity
Belongs to the glycosyl hydrolase 68 family.
Mass
46.762 kDa
Sequence
MLNKAGIAEPSLWTRADAMKVHTDDPTATMPTIDYDFPVMTDKYWVWDTWPLRDINGQVVSFQGWSVIFALVADRTKYGWHNRNDGARIGYFYSRGGSNWIFGGHLLKDGANPRSWEWSGCTIMAPGTANSVEVFFTSVNDTPSESVPAQCKGYIYADDKSVWFDGFDKVTDLFQADGLYYADYAENNFWDFRDPHVFINPEDGKTYALFEGNVAMERGTVAVGEEEIGPVPPKTETPDGARYCAAAIGIAQALNEARTEWKLLPPLVTAFGVNDQTERPHVVFQNGLTYLFTISHHSTYADGLSGPDGVYGFVSENGIFGPYEPLNGSGLVLGNPSSQPYQAYSHYVMTNGLVTSFIDTIPSSDPNVYRYGGTLAPTIKLELVGHRSFVTEVKGYGYIPPQIEWLAEDESSNSAAALSLLNK
Protein
Levansucrase: sacB

Gene
sacB
Protein
Levansucrase
Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Length
423 amino acids
Similarity
Belongs to the glycosyl hydrolase 68 family.
Mass
46.762 kDa
Sequence
MLNKAGIAEPSLWTRADAMKVHTDDPTATMPTIDYDFPVMTDKYWVWDTWPLRDINGQVVSFQGWSVIFALVADRTKYGWHNRNDGARIGYFYSRGGSNWIFGGHLLKDGANPRSWEWSGCTIMAPGTANSVEVFFTSVNDTPSESVPAQCKGYIYADDKSVWFDGFDKVTDLFQADGLYYADYAENNFWDFRDPHVFINPEDGKTYALFEGNVAMERGTVAVGEEEIGPVPPKTETPDGARYCAAAIGIAQALNEARTEWKLLPPLVTAFGVNDQTERPHVVFQNGLTYLFTISHHSTYADGLSGPDGVYGFVSENGIFGPYEPLNGSGLVLGNPSSQPYQAYSHYVMTNGLVTSFIDTIPSSDPNVYRYGGTLAPTIKLELVGHRSFVTEVKGYGYIPPQIEWLAEDESSNSAAALSLLNK
Protein
Levansucrase: sacB

Gene
sacB
Protein
Levansucrase
Organism
Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 / CIP 78.65)
Length
415 amino acids
Similarity
Belongs to the glycosyl hydrolase 68 family.
Mass
45.939 kDa
Sequence
MTNLNYTPTIWTRADALKVNENDPTTTQPIVDADFPVMSDEVFIWDTMPLRSLDGTVVSVDGWSVIFTLTAQRNNNNSEYLDAEGNYDITSDWNNRHGRARICYWYSRTGKDWIFGGRVMAEGVSPTSREWAGTPILLNEDGDIDLYYTCVTPGATIAKVRGKVLTSEEGVTLAGFNEVKSLFSADGVYYQTESQNPYWNFRDPSPFIDPHDGKLYMVFEGNVAGERGSHVIGKQEMGTLPPGHRDVGNARYQAGCIGMAVAKDLSGDEWEILPPLVTAVGVNDQTERPHFVFQDGKYYLFTISHKFTYADGLTGPDGVYGFLSDNLTGPYSPMNGSGLVLGNPPSQPFQTYSHCVMPNGLVTSFIDNVPTSDGNYRIGGTEAPTVKIVLKGNRSFVERVFDYGYIPPMKNIILN
Protein
Levansucrase: sacB

Gene
sacB
Protein
Sucrose-specific phosphotransferase enzyme IIB component
Organism
Lactococcus lactis subsp. lactis
Length
40 amino acids
Function
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport.
Mass
4.483 kDa
Fragment
single
Sequence
MNHKQVAERILNAVGRDNIQGARHCATRLRLVLKDTGVID