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rusA

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease rusA
Organism
Lactococcus phage r1t
Length
131 amino acids
Function
Endonuclease that resolves Holliday junction intermediates. Promotes DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity, though it can also cut branched DNA structures that lack the symmetry of Holliday junctions.
Similarity
Belongs to the RusA family.
Mass
16.001 kDa
Sequence
MKFEFEFELDKMPTTQQQKGIKKVKGKLQFYDRRGTNNYSLKAQLMKNKPKECFEKNVPLKLSVTFFYAIKQKKRWWQWKTSRPDLDNLMKNLQDYMTKLRYYSDDSQIVWLEAKKVNDEKNRIEIEITEV

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Aquifex aeolicus (strain VF5)
Length
126 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides.
Similarity
Belongs to the RusA family.
Mass
14.778 kDa
Sequence
MISEMEEIELYLSKLPVPKSNRYIRPKGGKVFKPPRVTNWEARAIWELREQFKGDAIDYEISVDITLILPNRRKRDIDNMLKSLWDVMEKAGVIKNDNLIFEVHTVKKIEKGKEGVIIKIRPFQSP

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease rusA
Organism
Enterobacteria phage 82
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates. Promotes DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity.
Similarity
Belongs to the RusA family.
Mass
13.885 kDa
Sequence
MNTYHITLPWPPSNNRYYRHNRGRTHISAEGQAYRDNVARIIKGSMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKASFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease rusA
Organism
Enterobacteria phage HK97
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates. Promotes DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity.
Similarity
Belongs to the RusA family.
Mass
14.067 kDa
Sequence
MNEYQFVLPYPPSLNTYWRRRGSQYYISDKGQKYRKDVQQIIRQLKLDIFTKSRLRIKVIADVPDSRRRDLDNILKGLLDSLIHAGFAEDDEQFDDIRVIRGVKVPGGRLGIKITELESV

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
Similarity
Belongs to the RusA family.
Mass
13.791 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRCRRDLDNLQKAAFDALTKAGFWLDDELVVDYRVVKMPVTKGGKLELTITELGDE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Escherichia coli O157:H7
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
Similarity
Belongs to the RusA family.
Mass
13.773 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHISAEGQAYRDNVARIIKGSMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGKLELTITELGNE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Escherichia coli O1:K1 / APEC
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
Similarity
Belongs to the RusA family.
Mass
13.846 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
Similarity
Belongs to the RusA family.
Mass
13.846 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
Similarity
Belongs to the RusA family.
Mass
13.846 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Escherichia coli (strain K12)
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.
Similarity
Belongs to the RusA family.
Mass
13.846 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Escherichia coli (strain UTI89 / UPEC)
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
Similarity
Belongs to the RusA family.
Mass
13.846 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE

Gene
rusA
Protein
Crossover junction endodeoxyribonuclease RusA
Organism
Shigella sonnei (strain Ss046)
Length
120 amino acids
Function
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
Similarity
Belongs to the RusA family.
Mass
13.89 kDa
Sequence
MNTYSITLPWPPSNNRYYRHNRGRTHISAEGQAYRDNVTRIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE