rumi

O-glucosyltransferase rumi

411 amino acids

Protein O-glucosyltransferase. Catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue found in the consensus sequence C-X-S-X-[PA]-C in epidermal growth factor-like repeats (PubMed:27428513). Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch.

Belongs to the glycosyltransferase 90 family.

47.735 kDa

MLINHLIVVLLISLVGTGGAEDDGLCSADQKSCAQSEPDQINEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGPKKDEL

rumi

O-glucosyltransferase rumi

409 amino acids

Protein O-glucosyltransferase. Catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue found in the consensus sequence C-X-S-X-[PA]-C in epidermal growth factor-like repeats. Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch.

Belongs to the glycosyltransferase 90 family.

47.314 kDa

MLINVVLIILLVGLNGKASGQNQGLCSPDENASCADSSDTQDEFSFNILRKIKKALASYQPCSSDANDANCSCHAAVIKSDLAPYKATGVSRQMIESSARYGTRYKIYEKRLYREENCMFPARCQGIEHFLLPLVATLPDMDLVINTRDYPQINMAWGNGAQGPILSFSKTKDHRDIMYPAWTFWAGGPATKLHPRGIGRWDLMREKLEKRAAAIPWSQKRELGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPPAGEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCQSLVFHVGDEWQEFFYDQLKPWVHYVPLKNYPSQQEYEELLTFFRKNDALAQEIAQRGRDFIWQHLRMKDIKCYWRRLLKSYVKLLTYEVQPEDQLIHIQPAKDEL